Penta-hepta defect chaos in a model for rotating hexagonal convection

In a model for rotating non-Boussinesq convection with mean flow we identify a regime of spatio-temporal chaos that is based on a hexagonal planform and is sustained by the {\it induced nucleation} of dislocations by penta-hepta defects. The probability distribution function for the number of defects deviates substantially from the usually observed Poisson-type distribution. It implies strong correlations between the defects inthe form of density-dependent creation and annihilation rates of defects. We extract these rates from the distribution function and also directly from the defect dynamics.Comment: 4 pages, 5 figures, submitted to PR

Global Citizenship and Business Education, Part 1: Antecedents and Foundations

Whereas national sovereignty persists as the primary form of political organization, the interconnectedness of today's world implies that any citizen's rights and obligations are no longer confined within national boundaries while many societal issues require global civic responses. Thus, business leaders need to be educated on the skills and values that characterize global citizenship in order for them to be accountable and act accordingly. This article traces the historical foundations of the concept of global citizenship, its definition and legitimacy. We also list the major skills and values that global citizens must possess in order to act accordingly

Global Citizenship and Business Education, Part 2: The Role of Business Schools

Over the last decade we have seen increased demands for full stakeholder models in global decision-making and greater emphasis by accrediting agencies that business schools show their commitment to societal ends. The COVID-19 pandemic has brought these issues to the fore. We trace early developments in how business schools dealt with these demands and analyze the data from the Aspen Institute's survey of business schools' commitment to global citizenship programs. We then review more recent efforts and report on several institutional and collaborative efforts to promote a global citizenship agenda among business schools and their curricula

Probing galaxy evolution through the internal colour gradients, the Kormendy relations and the Photometric Plane of cluster galaxies at z~0.2

We present a detailed analysis of the photometric properties of galaxies in the cluster \A2163B at redshift z~0.2. R-, I- and K-band structural parameters, (half light radius r_e, mean surface brightness _e within r_e and Sersic index n) are derived for N~60 galaxies, and are used to study their internal colour gradients. For the first time, we use the slopes of optical-NIR Kormendy relations to study colour gradients as a function of galaxy size, and we derive the Photometric Plane at z~0.2 in the K band. Colour gradients are negligible at optical wavelengths, and are negative in the optical-NIR, implying a metallicity gradient in galaxies of ~0.2 dex per radial decade. The analysis of the Kormendy relation suggests that its slope increases from the optical to the NIR, implying that colour gradients do not vary or even do become less steep in more massive galaxies. Such a result is not simply accomodated within a monolithic collapse scenario, while it can be well understood within a hierarchical merging framework. Finally, we derive the first NIR Photometric Plane at z~0.2, accounting for both the correlations on the measurement uncertainties and the selection effects. The Photometric Plane at z~0.2 is consistent with that at z~0, with an intrinsic scatter significantly smaller than the Kormendy relation but larger than the Fundamental Plane.Comment: 18 pages, 12 figures, A&A in pres

朝鮮民画とその現代的表現についての考察

多摩美術大学201

Polyglutamine-expanded androgen receptor interferes with TFEB to elicit autophagy defects in SBMA.

Macroautophagy (hereafter autophagy) is a key pathway in neurodegeneration. Despite protective actions, autophagy may contribute to neuron demise when dysregulated. Here we consider X-linked spinal and bulbar muscular atrophy (SBMA), a repeat disorder caused by polyglutamine-expanded androgen receptor (polyQ-AR). We found that polyQ-AR reduced long-term protein turnover and impaired autophagic flux in motor neuron-like cells. Ultrastructural analysis of SBMA mice revealed a block in autophagy pathway progression. We examined the transcriptional regulation of autophagy and observed a functionally significant physical interaction between transcription factor EB (TFEB) and AR. Normal AR promoted, but polyQ-AR interfered with, TFEB transactivation. To evaluate physiological relevance, we reprogrammed patient fibroblasts to induced pluripotent stem cells and then to neuronal precursor cells (NPCs). We compared multiple SBMA NPC lines and documented the metabolic and autophagic flux defects that could be rescued by TFEB. Our results indicate that polyQ-AR diminishes TFEB function to impair autophagy and promote SBMA pathogenesis

Physico-chemical characterization of polyamide NF/RO membranes: Insight from streaming current measurements

International audienceTangential streaming current measurements were performed to investigate the surface charge properties and the charge formation mechanism of various NF/RO membranes. Unlike what is usually done in electrokinetic studies of membranes, experiments were conducted with degassed background solutions under a controlled atmosphere by means of nitrogen gas in order to get accurate electrokinetic measurements even in the basic range of pH. It was demonstrated that the streaming current technique implemented with these rigorous experimental conditions is a reliable tool to verify the presence of an additional coating on a commercial TFC membrane. It was also shown that these electrokinetic measurements allow a more clear discrimination between coated and uncoated membranes than the ATR-FTIR technique. Moreover, experiments performed with and without a nitrogen environment revealed specific adsorption of bicarbonate and carbonate ions coming from the dissolution of carbon dioxide in the air onto the surface of RO polyamide membranes containing hexafluoroalcohol functional groups