Osmanlı Dönemi Botanik Ressamlığı ile Günümüz Sanat, Tasarım ve Bilimsel Resimlemeye Yansımaları

Tarih boyu bitkilerin insan sağlığı üzerindeki olumlu etkileri tıp ilmiyle uğraşan bilim adamlarının gündeminde olmuştur. Bitkilerden elde edilen ilaç ve destekleyici gıdalar geçmişten günümüze aktarılarak bu konuda oldukça geniş bir kütüphanenin oluşmasına da zemin hazırlamıştır. Günümüzde Avrupa ülkelerinde Avisenna olarak bilinen İbn-i Sina’nın kitapları sonradan Batı medeniyeti üniversitelerinde ders kitabı olarak okutulmaya başlanmıştır. Bunun dışında, Ali Bin Abbas, Ammar Musuli, Ali bin İsa, Ebû Bekir er-Razi, İbn-i Nefis, Akşemsettin Hz, İbn-i Hâtip, Abbâs Vesîm Efendi gibi dünyaca ünlü Müslüman bilim adamları ve hekimleri tıp alanında ve insanlığın her yönden gelişmesine katkıda bulunan pek çok bilimsel eserler kaleme almışlardır. Osmanlı döneminde de pek çok tıp alimi eserleriyle insanlığın hizmetine değerli eserler kazandırmışlardır. Osmanlı döneminin son dönemine gelen botanik ressamlığı her ne kadar titiz ve sıkı çalışmaların neticesi olarak ortaya çıkarılmışsa da ne yazık ki Cumhuriyet Dönemi sonrası gerekli ilgiyi görememiştir. Son yıllarda ülkemizde pek çok sanat kursunda botanik ressamlığı dersi verilse de halen bu konuda hazırlanmış eser sayısı diğer sanatlarla kıyaslandığında, sınırlıdır. Araştırma Osmanlı Döneminde yapılmış olan botanik konulu bilimsel eserler ile günümüz botanik ressamlığının sanat ve tasarım açısından incelenmesi için yapılmıştır

Tissue mimicking phantoms for microwave brain stroke imaging

Within the past decade, once limited biomedical application of microwave imaging started to expand from the breast cancer imaging to imaging of other anomalies. One such anomaly is the brain stroke where the application of microwave imaging is two folds. One application is the identifying the source of stroke that is to categorize whether the stroke stems from blockage (ischemic) or bleeding (hemorrhagic). The other possible application is the continuous imaging of the progression of hemorrhagic stroke during the post-acute stage. In this work, a phantom for emulating the dielectric properties of the lossy brain tissue is given for testing of the microwave devices for continuous monitoring. The recipe is simple and is composed by mixing carboxymethyl cellulose, ethylene glycol, and deionized water. The recipe is simple, has viscose texture, and can be easily composed. Dielectric property measurements and comparison with the literature data is given in this paperThis project has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie grant agreement No 750346

Diagnosis of Periprosthetic Joint Infection: The Utility of Biomarkers in 2023

Periprosthetic joint infection (PJI) is a rare yet devastating complication following total joint arthroplasty (TJA). Early and accurate diagnosis of PJI is paramount in order to maximize the chances of successful treatment. However, we are yet to identify a single “gold standard” test for the diagnosis of PJI. As a result, the diagnosis of PJI is often challenging. Currently, the 2018 ICM definition of PJI is the only validated diagnostic criteria available. This article will review the importance of serum and synovial biomarkers in the diagnosis of PJI. In addition, it will provide a brief overview of the emerging modalities for the identification of infections in this setting

A Primary Leiomyosarcoma of the Thyroid Gland: A Case and Literature Review

Introduction: We want to present a rare case of Primary leiomyosarcoma of the thyroid (PLT) gland and review the literature on PLT including the differential diagnoses, pathology, and alternative treatment strategies.Presentation of Case: A 56-year-old man who underwent left side total thyroidectomy with diagnosis of substernal goiter. On pathologic examination, three different pathology clinics had a common opinion that this was a grade 3 pleomorphic sarcoma of thyroid itself. Positron Emission Tomography (PET/CT) obtained one month after surgery displayed no distant metastases. Loco regional radiotherapy (RT) to the thyroid bed was delivered up to a dose of 59.4 Gray (Gy) in 1.8 Gy daily fractions. PET/CT obtained three months after RT showed bilateral multiple lung metastases without loco regional recurrence. The patient received 6 courses of doxorubicin and cyclophosphamide based chemotherapy. A new PET/CT scan showed only two metabolically active metastases on both lungs. Because of disappearance of small metastases, the patient underwent sequential bilateral metastasectomy in one month interval. Pathology results verified the metastases of PLT. The patient is still alive without any signs of disease 6 years after RT and he is the only long surviving case reported up to now.Conclusion: The treatment protocols for PLT have not been well established yet, because of their rareness and poor prognosis. We believe that our case may be directive for PLT treatment

Analysis of October 23 (Mw 7.2) and November 9 (Mw 5.6), 2011 Van Earthquakes Using Long-Term GNSS Time Series

The eastern Anatolia provides one of the best examples of an area of rapid deformation and intense contraction that is the consequence of an active continental collision between the Arabian and Eurasian plates leading to large and devastating earthquakes. The latest evidence of the active tectonism in the region is revealed by two remarkable seismic events; Van-Tabanli (Mw 7.2, October 23, 2011) and Van-Edremit (Mw 5.6, November 9, 2011) earthquakes. The study of the earthquake cycle and observation of geodetic and seismic deformation in this region is very important to hazard assessments. In this study, the inter-seismic, co-seismic, and post-seismic movements caused by the above-mentioned earthquakes were investigated using the time series of 2300 days of Global Navigation Satellite Systems (GNSS) observations of the local stations selected from the network of the Continuously Operating Reference Stations, Turkey (CORS-TR). For the inter-seismic period, approximately 1100 daily data were obtained from 21 CORS-TR stations (prior to the earthquakes between October 1, 2008 and October 23, 2011) and evaluated using the GAMIT/GLOBK software. The behaviour of these stations was investigated by processing 1 Hz data from the GNSS stations during the earthquakes on the GAMIT/TRACK software. In addition to October 23 and November 9, the GNSS data on one day before and after the earthquakes was assessed to determine co-seismic deformations. During the October 23 earthquake, hanging-wall deformation of about 60 mm was detected in the SW direction at the MURA station. However, at the VAAN station, deformation of 200 mm (value predicted by time series) was observed in the footwall block in the NW direction. There were not any significant changes at the stations during the November 9 earthquake. For the post-seismic period, the GNSS data from 2012 to 2015 was evaluated. According to the observations, post-seismic deformation continued at the stations close to the epicenter of the earthquake.Anatolia oriental provee uno de los mejores ejemplos de un área de rápida deformación e intensa contracción, consecuencia de una colisión continental activa entre la placa Arábiga y la Euroasiática, lo que causa grandes y devastadores terremotos. Dos notables terremotos son evidencia de la actividad tectónica de la región: los terremotos Van-Tabanli (7.2 Mw. 23 de octubre de 2011) y Van-Edremit (5.6 Mw, 9 de noviembre de 2011). El estudio del ciclo sísmico y la observación de las deformaciones geodésicas y sísmicas en esta región es fundamental para la evaluación de riesgo. En este estudio, se investiga las fases inter-, co- y post-sísmicas asociados a estos terremotos a través de 2300 días de observaciones del Sistema Global de Navegación por Satélite (GNSS, por sus siglas en inglés) de estaciones locales seleccionadas de la red de Estaciones de Referencia de Funcionamiento Continuo en Turquía (CORS-TR). Para el periodo intersísmico se obtuvieron aproximadamente 1100 datos diarios de 21 estaciones CORS-TR (anteriores a los terremotos entre el 1 de octubre de 2008 y el 23 de octubre de 2011) y evaluados con el software GAMIT/GBLOK. El comportamiento co-sísmico fue investigado procesando datos de 1 Hz de las estaciones GNSS durante los terremotos en el software GAMIT/TRACK. Adicionalmente se evaluaron datos del GNSS un día antes y un día después de los terremotos para determinar las deformaciones cosísmicas. Durante el terremoto del 23 de octubre, en el bloque colgante se detectó una deformación de 60 mm en dirección SW (estación MURA). En la estación VAAN en el bloque yacente se observó una deformación de 200 mm en dirección NW (valor predicho por series temporales). Durtante el terremoto del 9 de Noviembre no se observó cambios significativos. Para la fase post-sísmica se evaluaron los datos de la GNSS del 2012 al 2015. Según las observaciones, la deformación postsísmica continuó en las estaciones cercanas al epicentro del terremoto

Acylated and Desacylated Ghrelin, Preptin, Leptin, and Nesfatin-1 Peptide Changes Related to the Body Mass Index

This study examines the levels of acylated and desacylated ghrelin, preptin, leptin, and nesfatin-1 peptide changes related to the body mass index (BMI). The subjects were allocated to 5 groups depending on their BMIs as follows: Group I (BMI 40 kg/m2). Serum acylated and desacylated ghrelin, preptin, and leptin levels were measured by the enzyme-linked immunosorbent assay (ELISA) and nesfatin-1 was measured by the enzyme immunoassay (EIA). Desacylated ghrelin levels showed a gradual and statistically significant drop from Group I to Group V, while preptin and leptin levels exhibited a gradual and significant increase from Group I to Group IV. Serum nesfatin-1 levels gradually, but not significantly, increased from Group I to Group III and showed a significant decrease in Groups IV and V. In conclusion, leptin, preptin, and acylated ghrelin (AG) levels increased with higher BMI, whereas desacylated ghrelin (DAG) decreased and nesfatin-1 showed no clear relationship to BMI

Incidence, hospital costs and in-hospital mortality rates of surgically treated patients with traumatic cranial epidural hematoma

Background: In this study, the patients who were operated in two clinics due to traumatic cranial epidural hematoma (EDH) were assessed retrospectively and the factors that increase the costs were tried to be revealed through conducting cost analyses. Methods: The patients who were operated between 2010 and 2016 with the diagnosis of EDH were assessed in terms of age, sex, trauma etiology, Glasgow coma scale (GCS) at admission, the period from trauma to hospital arrival, trauma-related injury in other organs, the localization of hematoma, the size of hematoma, length of stay in the intensive care unit (ICU), length of antibiotherapy administration, number of consultations conducted, total cost of in-hospital treatments of the patients and prognosis. Results: Distribution of GCS were, between 13-15 in 18 (36%) patients, 9-13 in 23 (46%) patients and 3-8 in 9 (18%) patients. The reasons for emergency department admissions were fall from high in 29 (58%) patients, assault in 11 (22%) patients and motor vehicle accident in 10 (20%) patients. The average cost per ICU stay was 2838 $(range=343-20571$). The average cost per surgical treatment was 314 $. ICU care was approximately 9 times more expensive than surgical treatment costs. The mortality rate of the study cohort was 14% (7 patients). Conclusion: The prolonged period of stay in the ICU, antibiotherapy and repeat head CTs increase the costs for patients who are surgically treated for EDH

Aktivna deformacija Zemljine površine utvrđena preciznim nivelmanskim premjerom u Afyon-Akşehir grabenu u Zapadnoj Anadoliji u Turskoj

In the actively deforming region of western Anatolia, crustal deformation is accommodated by destructive earthquakes and a variety of aseismic events. In this study, we investigated the 2016–2017 aseismic sequence located in the Bolvadin Fault, one of the segments of the Akşehir-Simav Fault System of western Anatolia by analysing surface deformation derived from detailed geological mapping. Our findings suggest that surface deformation in the Bolvadin Fault is accommodated by aseismic episodes. During the field studies in the Bolvadin area, progressive surface deformations, such as surface faults and earth fissures with a length of 800 meters to 3 kilometres and strike of N15°E to N70°E were mapped on a 1/5000 scale. Furthermore, a levelling network was established to calculate the vertical displacements and deformation rate along the surface deformations. Precision level measurements were undertaken in 2016 and 2017. On the routes to the NW of the Bolvadin settlement, a vertical deformation rate of 30 mm/yr was detected in the period of 2016–2017, and a large deformation rate of 40 mm/yr was detected in the same period.Aktivna deformacija Zemljine kore se u regiji Zapadne Anadolije kompenzira razornim potresima i drugim seizmičkim događajima. U ovom smo radu na temelju detaljnog geološkog kartiranja analizirali deformaciju površine kako bismo proučili niza seizmičkih događaja u razdoblju 2016.–2017. na lokaciji rasjeda Bolvadin, jednoga od segmenata rasjednoga sustava Akşehir-Simav u Zapadnoj Anadoliji. Naši rezultati ukazuju na to da se površinska deformacije kompenzira tijekom aseizmičkih epizoda. Tijekom terenskih istraživanja u području Bolvadin, progresivne su površinske deformacije, poput površinskih rasjeda ili pukotina duljina od 800 m do 3 km, pružanja N15°E do N70°E, kartirane u mjerilu 1:5 000. Nadalje, uspostavljena je nivelmanska mreža kako bi se izmjerila brzina pomaka i deformacija. Precizna nivelmanska mjerenja izvedena su 2016. i 2017. godine. Na pravcima usmjerenima SZ od naselja Bolvadin, ustanovljena je brzina vertikalne deformacije od 30 mm/god., a u istom je razdoblju izmjerena i velika brzina deformacije od 40 mm/god

Incidence, hospital costs and in-hospital mortality rates of surgically treated patients with traumatic cranial epidural hematoma

Background: In this study, the patients who were operated in two clinics due to traumatic cranial epidural hematoma (EDH) were assessed retrospectively and the factors that increase the costs were tried to be revealed through conducting cost analyses.Methods: The patients who were operated between 2010 and 2016 with the diagnosis of EDH were assessed in terms of age, sex, trauma etiology, Glasgow coma scale (GCS) at admission, the period from trauma to hospital arrival, trauma-related injury in other organs, the localization of hematoma, the size of hematoma, length of stay in the intensive care unit (ICU), length of antibiotherapy administration, number of consultations conducted, total cost of in-hospital treatments of the patients and prognosis.Results: Distribution of GCS were, between 13-15 in 18 (36%) patients, 9-13 in 23 (46%) patients and 3-8 in 9 (18%) patients. The reasons for emergency department admissions were fall from high in 29 (58%) patients, assault in 11 (22%) patients and motor vehicle accident in 10 (20%) patients. The average cost per ICU stay was 2838 $(range=343-20571$). The average cost per surgical treatment was 314 $. ICU care was approximately 9 times more expensive than surgical treatment costs. The mortality rate of the study cohort was 14% (7 patients).Conclusion: The prolonged period of stay in the ICU, antibiotherapy and repeat head CTs increase the costs for patients who are surgically treated for EDH

“The Lolelaplap (Marshall Islands) in Us: Sailing West to East (Ralik→Ratak) to These Our Atolls (Aelon Kein Ad) Ad Jolet Jen Anij (Our Blessed Inheritance from God)”

This paper discusses the expansion of Oceania through a Marshallese indigenous lens as a focal point. It explains that decolonizing methodologies allows reclaiming of space for mental liberation and reassurement of constitutional rights. It highlights similar occurrences of decolonization practices meeting resistance in the 21st century all while strengthening the human right argument that no human deserves any less than their fellow human brothers and sisters. It argues that an indigenous imagery can only be viewed through an indigenous lens where the researches’ level of purity is retained and unfiltered. It nevertheless argues that Marshallese ethnolinguistics reveal the same cultural practices in America, Judeo-Christianity, and Oceania thus dictating the reality that “we are the same not withstanding one stays here and one there (Bedbedjin Bedbedjen, Bedbedjinma wot Kwe)”. It further explains the importance in these similarities and how Marshallese spirituality predates introduced American Judeo-Christianity despite the latter attempting to marginalize the former. It concludes by stating that Marshallese contributions on the global stage are rooted in that culture of love (IaKwe) which is echoed by the custom(s) revealing the significance of Marshallese validation academically, spiritually, economically, & socially to prevent institutionalized discrimination. This paper ends stating that the agency to know one’s self and how one should fit in the world, is a human right in itself and Marshallese are entitled to this sense of self worth through knowing thy self by thy self where real thinking takes place in one’s own mind as we all live our own lives