The relationship between the preferences of the oral glucose screening test and the levels of health literacy and perinatal anxiety of pregnancy

Peer reviewedPublisher PD

Accumulation of Oxidized Low-Density Lipoprotein in Psoriatic Skin and Changes of Plasma Lipid Levels in Psoriatic Patients

Background. Psoriasis is a chronic inflammatory skin disease characterized by an accelerated turnover of epidermal cells and an incomplete differentiation in epidermis with lesion. However, the exact etiology of psoriasis is unknown. Abnormalities in essential fatty acid metabolism, free radical generation, lipid peroxidation, and release of lymphokines have been proposed. Objective. Our purpose was to evaluate the plasma lipids and oxidized low-density lipoprotein accumulation in psoriatic skin lesion in order to ascertain the possible participation of oxidative stress and oxidative modification of lipids in pathogenesis of psoriasis. Methods. The study group included 84 patients with psoriasis, and 40 sex- and age-matched healthy volunteers. Blood lipid profile was determined. Psoriatic and nonlesional skin samples of psoriatic patients were evaluated for the presence of oxidized low-density lipoprotein by using an immune-fluorescent staining method. Results. The mean levels of lipids (total cholesterol, triglyceride, and LDL cholesterol) in patients with psoriasis were found to be significantly higher than those of healthy subjects. Psoriatic skins were shown positive oxidized low-density lipoprotein staining. There was no staining in nonlesional skin samples of the same individuals. Conclusion. Lipid peroxidation mediated by free radicals is believed to be one of the important causes of cell membrane destruction and cell damage. This study shows for the first time the accumulation of oxidized low-density lipoprotein in psoriatic skin lesion. We believe that accumulation of ox-LDL in psoriatic skin may have an important role in the immune-inflammatory events that result in progressive skin damage

Relation of age and sex with carotid intima media thickness in healthy children

Background/aim: To investigate the age- and sex-associated carotid intima media thickness (cIMT) changes in healthy children to determine the age- and sex-specific normal range of values for childhood. Materials and methods: This study examined 91 healthy school-age children aged 7-15 years prospectively. Standardized sonographic cIMT measurements and analyses were performed. Body mass index and blood pressure were obtained, and atherosclerotic risk factors were investigated. Age- and sex-specific cIMT measurements for different age groups were calculated and the relation with sex was investigated. Results: Regarding the total study group, mean cIMT measurements for age groups 7-9, 10-12, and 13-15 years were 4.1 ± 0.5 mm, 4.4 ± 0.6 mm, and 4.6 ± 0.4 mm, respectively. cIMT did not differ between boys and girls in the same age group. Age related analyses showed significant variations among the age groups with positive correlation between cIMT and age. Conclusion: Our results suggest that age-related physiologic thickening of the carotid artery intima-media occurs not only in adults but also in children and that sex is not a factor for cIMT differences in childhood. © TÜBİTAK

Normal Doğumda Öğrenci Hemşireler ve Klinik Hemşireler Tarafından Verilen Bakımın Anne Memnuniyetine Etkisi

Amaç: Bu araştırma öğrenci hemşireler ve klinik hemşirelerinin normal doğum yapan annelere doğum salonunda verdikleri hemşirelik bakımının anne memnuniyet düzeyine etkisini belirlemek amacıyla yapılmıştır. Yöntem: Araştırmanın verileri anket formu, Normal Doğumda Anne Memnuniyetini Değerlendirme Ölçeği ve Newcastle Hemşirelik Bakımı Memnuniyet Ölçeği ile toplanmıştır. Verilerin değerlendirilmesinde bağımsız gruplar için t testi ve korelasyon analizi kullanılmıştır. Bulgular: Öğrenci hemşirelerden bakım alan annelerin memnuniyetleri klinik hemşirelerinden bakım alan gruba göre daha yüksek olup gruplar arasındaki fark istatistiksel olarak anlamlıdır (p<0.05). Aynı şekilde Annelerin Doğum Memnuniyeti ve Newcastle Hemşirelik Bakım ölçeğinden aldıkları puanlar arasında pozitif yönde anlamlı bir ilişki belirlenmiştir. Sonuç: Doğum eylemi ve doğum sonu dönemde hasta merkezli yaklaşımla annelerin kendisi ve bebeğiyle ilgili bakım gereksinimleri ve beklentilerinin öğrenci hemşire tarafından birebir karşılanması annelerin memnuniyetini arttırmıştır