Introducing a new risk factor for Lumbar Disc Herniation in females : vertical angle of the sacral curvature

Kanat, Ayhan/0000-0002-8189-2877WOS: 000313134700003PubMed: 23323164Objective : To characterize the importance of the vertical angle of the sacral curvature (VASC) in lumbar disc herniations. Methods : Morphological data derived from lumbar sagittal MRI imaging. the statistical significance of the findings are discussed. the angles of 60 female patients with lumbar disc herniations (LDH) were compared with the 34 female patients without LDH. Results : 128 of the 185 patients met our inclusion criteria. the vertical angle of sacral curvature is statistically significantly bigger in females with lumbar disc herniations when compared to subjects in control group, 28.32 and 25.4, respectively. (p=0.034<0.05). Same difference was not seen in males. Conclusion : the vertical angle of sagittal sacral curvature may be another risk factor in females with lumbar disc herniations

A newborn with moderate hemophilia A with severe intracranial and extracranial hemorrhage: A case report

Intracranial hemorrhage among term newborns is a rare clinical condition with high morbidity and mortality. Although major bleeding is relatively uncommon, the incidence of intracranial hemorrhage in hemophilic children is higher during the first few days of life than at any other stage in childhood, which relates to the trauma of delive ry. Here, we reported a newborn case diagnosed with moderate hemophilia A, without the presence of a positive family history of hemophilia and presenting with intracranial and extracranial hemorrhage and we aimed to emphasize that the early diagnosis and replacement therapy carries an essential importance

The Influence of Orientalism in the 18th and 19th Century Opera Librettos

This study aims to trace the change and transformation of meaning and influence of orientalism and in the West from the 18th century through the 19th century in the operas where both content and visual codes were penetrated in the subtlest way, which first evolved geographically and politically, then diplomatically and culturally, and finally the purpose of domination by the West. While opera librettos embodied orientalism visually, the evolving content of orientalism shaped the operas. From this viewpoint, this study discusses the interaction between the East and the West in the 18th century, and the reflection of the historical memory in the performing arts in the 19th century, in which the attempts for domination emerged. In this context, ‘Tamerlano’ Opera by George Frederick Händel and the ‘Abduction from the Seraglio’ Opera by Wolfgang Amadeus Mozart in the 18th century are looked through, and ‘Aida’ Opera by Giuseppe Verdi in the 19th century is construed subsequently

Interesting negative correlation between transorbital optic nerve sheath diameter and Evans' index values; can it be predictive for failure of endoscopic third ventriculostomy?

Background: Currently, Endoscopic third ventriculostomy (ETV) is one of the commonly used surgical options for the treatment of non-communicating hydrocephalus but reported success rates from ETV vary considerably, and a reliable noninvasive means to detect the efficacy of ETV is still lacking. In this study, the changes in Evans's Index and the transorbital optic nerve sheath (ONSD) diameter measurement after endoscopic third ventriculostomy were compared. Methods: Preoperative and early postoperative ultrasonographic ONSD measurement and preoperative and postoperative 3 months Evans' index of patients with hydrocephalus on whom ETVs were performed between 1 February 2018 and 23 May 2022 and analyzed. Results: The chart of 8 male and 2 female patients was analyzed. Their median age at presentation was 5.3 years (range 1 - 14 years). Mean ONSD values were 5.66 mms in the preoperative period, which was decreased to a mean of 4.17 mms in the early postoperative period. The Evans' index was 0.5320 in the preoperative period; however, it decreased to 0.4460 in the postoperative 3rd months. The preoperative and early postoperative mean ONSD values and Evans' Index of patients were significantly different. Interestingly, a negative correlation was also observed between ONSD values and Evans' index. Conclusions: ONSD measurement and Evans' index have been commonly used after ETV procedures In pediatric patients with hydrocephalus. Still, there is an unexplained negative correlation between ONSD and Evans' index values. This study indicates that the two measures (Evans's index and ONSD) should be considered when performing follow-up examinations in patients after ETV

Frontal sinus asymmetry: Is it an effect of cranial asymmetry? X-ray analysis of 469 normal adult human frontal sinus

Kanat, Ayhan/0000-0002-8189-2877WOS: 000218657400011PubMed: 26752894Background and Aims: There is no study in the literature that investigates an asymmetric morphological feature of the frontal sinus (FS). Materials and Methods: Four hundred and sixty-nine consecutive direct X-rays of FSs were analyzed for the asymmetry between the right and left sides. When an asymmetry in the height and contour of the FS existed, this difference was quantified. Results: of the 469 patients, X-rays of 402 patients (85.7%), there was an asymmetry between right and left sides of the FS. of these 235 (50.1%) were dominant on the left side, whereas 167 (35.6%) were dominant on the right, the sinuses of remaining 67 patients (14.3%) was symmetric. Statistical Analysis: the comparisons between parameters were performed using Wilkinson signed rank test. the relationship between handedness and sinus asymmetrywas also examined by two proportions test. There is statistically significant difference between the dominance of left and right FS. Conclusions: Hemispheric dominance may have some effect (s) of on sinus asymmetry of the human cranium. Surgeons sometimes enter the cranium through the FS and knowledge of asymmetric FS is important to minimize surgical complications

Effects of Metoprolol on Experimental Spinal Cord Ischemia-Reperfusion Injury in Rats

Aim: The aim of this study was to investigate the neuroprotective effect of metoprolol and its efficacy in reducing lipidperoxidation levels in the spinal cord ischemia-reperfusion model in rats.Material and Methods: Twenty (20) Sprague-Dawley female rats weighing between 220 gr and 280 gr were randomlydivided into 3 groups. Only laparotomy was performed in the control group, and the aorta abdominalis was revealed. Inthe groups other than the control group, clip compression was applied to the aorta abdominalis for 45 minutes. Theischemia group was not given any medication. Metoprolol was administered intraperitoneally at 0.5 mg/kg to themetoprolol group. Motor examination was made according to Tarlov scale at the 1st and 24th hours and then, spinalcords of all rat models were removed. Spinal cord tissue samples were collected for histopathological examination andfor determining malondialdehyde (MDA) level. All rats were sacrificed by draining blood after their motorexaminations.Results: According to motor examination findings at the 1st and 24th hours, metoprolol resulted in a statisticallysignificant improvement in recovery (p=0.045). Histopathological examinations revealed that metoprolol contributed toneurological recovery by reducing neuronal necrosis. MDA levels, which is an indicator of lipid peroxidation, weresignificantly lower in the metoprolol group when compared to the ischemia group (p=0.001).Conclusion: Metoprolol was found to be significantly effective in reducing and/or preventing spinal cord ischemiareperfusion injury

Efficient and accurate electromagnetic analysis of three-dimensional nano-optical structures

We present computational analysis of optical nanostructures, including but not limited to frequency-selective surfaces, metamaterials, nanoantennas, nanowires, and photonic crystals. A rigorous implementation based on surface integral equations and the multilevel fast multipole algorithm is developed for the analysis of such three-dimensional complex structures, without resorting to infinity, self-similarity, periodicity or homogeneity assumptions. The developed simulation environment provides accurate analysis of nanooptical structures to expand our knowledge on these important components of the state-of-the-art technology