Green Building in the US and China: A law and economics perspective

The central question of this study is how instruments can be mixed to promote Green Building (GB). The following sub-questions will further answer the central question: (i) What does it mean to build green? (ii) Why do instrument mixes make sense? (iii) What are the instruments working for GB compliance? How do they work? (iv) What are the possible ways to instrument mixes for GB

Green building in China

Green buildings can play a role in helping countries meet their commitments under the Paris Agreement on Climate Change. Green building can provide an important contribution to sustainability, for example, by improving energy efficiency, by improving indoor air quality, and by effective waste treatment. In practice, we see that there is an increasing interest in various forms of green building. However, the existing literature has not identified the role of law in promoting green building. It is, moreover, striking that green building has taken off in a rather impressive manner in China. Although generally there are still huge environmental problems with which China is confronted, for many years already C

Reliability and validity of the Chinese post-discharge coping difficulty scale-parent form in parents of premature infants: a multicenter cross-sectional study

BackgroundThe measurement of the coping difficulties of parents of premature infants after discharge provides objective data for nurses to prepare infants for discharge. However, no Chinese scale has been developed to measure parents’ coping difficulties after their premature infants are discharged.AimTo translate the parent version of the Post-Discharge Coping Difficulty Scale (Ped-PDCDS) from English to Chinese and test the reliability and validity of the Chinese version in parents of premature infants.MethodsA multicenter cross-sectional study of 356 parents of premature infants was conducted. The scale was symmetrically translated. Validity was evaluated in terms of content, construct, discriminant, and convergent validities. Reliability was assessed in terms of internal consistency, split-half reliability, and test–retest reliability.ResultsThe Chinese Ped-PDCDS finally contained 11 items. Exploratory and confirmatory factor analyses results showed that the Chinese Ped-PDCDS had three dimensions, and the convergent and discriminant validities of the scale was satisfactory. The overall reliability, split-half reliability, and test–retest reliability of the scale was 0.85, 0.92, and 0.84, respectively.ConclusionThe Chinese Ped-PDCDS has adequate psychometric properties, and is an easy and appropriate instrument for measuring parents’ difficulty in coping with premature infants

Sciences of the USA 1418 -1421 ͉ PNAS

The discovery of the block-like structure of linkage disequilibrium (LD) in human populations holds the promise of delineating the etiology of common diseases. However, understanding the magnitude, mechanism, and utility of between-population LD sharing is critical for future genome-wide association studies. In this study, substantial LD sharing between six non-African populations was observed, although much less between African-American and non-African, based on 20,000 SNPs of chromosome 21. We also demonstrated the respective roles of recombination and demographic events in shaping LD sharing. Furthermore, we showed that the haplotype-tagged SNPs chosen from one population are portable to the others in East Asia. Therefore, we concluded that the magnitude of LD sharing between human populations justifies the use of representative populations for selecting haplotypetagged SNPs in genome-wide association studies of complex diseases. bottleneck ͉ genetic distance ͉ association study ͉ common disease ͉ genetic variant C omprehensive testing of the association between genetic variations in the human genome and common diseases holds the promise of delineating the genetic architecture of these diseases (1-5). Substantial sharing of the boundaries and specific haplotypes of linkage disequilibrium (LD) blocks between populations was observed (6). However, variations of haplotype and LD across populations were also reported, raising concerns on its practical hindrance for genomewide testing of association (7-9). Conflicting observations on the magnitude of LD sharing between human populations, therefore, call for a careful examination of the following three questions, which are fundamental in developing strategies for genomewide testing of association. First, measurement of LD sharing between populations should be made independent of the definition of LD blocks, which introduce inconsistent block boundaries (10). Second, the mechanisms that shape LD sharing between populations are yet to be fully explored although the roles of recombination hotspots and demographic events have been implicated To address the aforementioned questions, we typed Ͼ20,000 SNPs on chromosome 21 in seven populations: three representative continental populations [African-American (AFR), European (EUR), and Han Chinese (HAN)] and four other major East Asian (EA) populations. This design allows a close examination of LD sharing between continental groups as well as those within East Asia. In this report, we measured the LD sharing between populations independent of the definition of LD block; and we showed that bottleneck events play a critical role in shaping the LD sharing between Africans and nonAfricans, but much less so between non-Africans. An important question for applying HapMap results to disease studies is how tagSNPs selected from a HapMap population will be ported to disease studies performed in other populations. In this study, we showed that tagSNPs selected from representative continental populations are indeed portable to the others in the same continent for association studies, at least in East Asia, with reasonable efficiency. In addition, we proposed a simple guideline that allows a quick evaluation of the portability of tagSNPs between populations by typing a small number of SNPs. Results Overall 26,112 SNPs were selected and typed in this study, and the data from 19,060 SNPs passed the quality control criteria and were used for further analyses. The SNPs and quality control criteria for SNP selection are described in Materials and Methods. Seven world populations, including EUR, AFR, and five EA populations, were studied. The five EA populations, i.e., HAN, Miao (HMJ), Zhuang (CCY), Wa (WBM), and Uighur (UIG), represent five major linguistic families spoken in East Asia. Preservation of LD between populations, i.e., LD sharing (S, or S AB when the population A was given as reference), is measured by the proportion of SNP pairs in LD in one population (population A or the reference) that are also in LD in another (population B). In this study, LD sharing was estimated without invoking the inference of haplotype blocks; therefore, the measure is independent of the definition of haplotype blocks. LD between two loci was measured in r 2 (16). Detail for the measure of LD sharing is described in Materials and Methods. LD sharing between EAs ranges from 63-74% for r 2 Ն 0.1 and 70-84% for r 2 Ն 0.5 (se

2D Materials-based platforms for electroanalysis applications

A new class of nanomaterials called "2D materials" (2DMs) is attracting recently the electrochemical sensing field due to the unique physicochemical properties associated to their chemical structure, formed by ultra-thin layers. In this review, we summarize the recent advances in the electroanalysis area using 2DMs giving first a brief overview on the structure, synthesis and properties of these materials followed by the analysis of their advantages while used in the development of electrochemical sensors

Green building in China

Green buildings can play a role in helping countries meet their commitments under the Paris Agreement on Climate Change. Green building can provide an important contribution to sustainability, for example, by improving energy efficiency, by improving indoor air quality, and by effective waste treatment. In practice, we see that there is an increasing interest in various forms of green building. However, the existing literature has not identified the role of law in promoting green building. It is, moreover, striking that green building has taken off in a rather impressive manner in China. Although generally there are still huge environmental problems with which China is confronted, for many years already C