Inherent Negative Refraction on Acoustic Branch of Two Dimensional Phononic Crystals

Guided by theoretical predictions, we have demonstrated experimentally the existence of negative refraction on the lowest two (acoustic) passbands (shear and longitudinal modes) of a simple two dimensional phononic crystal consisting of an isotropic stiff (aluminum) matrix and square- patterned isotropic compliant (PMMA) circular inclusions. At frequencies and wave vectors where the refraction is negative, the effective mass density and the effective stiffness tensors of the crystal can be positive-defnite, and that, this is an inherent property of phononic crystals with an isotropic stiff matrix containing periodically distributed isotropic compliant inclusions. The equi-frequency contours and energy ux vectors as fuctions of the phase-vector components, reveal a rich body of refractive properties that can be exploited to realize, for example, beam splitting, focusing, and frequency filtration on the lowest passbands of the crystal where the dissipation is the least. By proper selection of material and geometric parameters these phenomena can be realized at remarkably low frequencies (large wave lengths) using rather small simple two-phase unit cells. Keywords: Doubly periodic phononic crystals, acoustic branch negative refraction, beam splitting, focusing, imaging, frequency filtration at large wave length

Does TP53 increase the sensitivity of CA125 in early detection of ovarian cancer?

https://openworks.mdanderson.org/sumexp22/1149/thumbnail.jp

Expansion of Thaumarchaeota habitat range is correlated with horizontal transfer of ATPase operons.

Thaumarchaeota are responsible for a significant fraction of ammonia oxidation in the oceans and in soils that range from alkaline to acidic. However, the adaptive mechanisms underpinning their habitat expansion remain poorly understood. Here we show that expansion into acidic soils and the high pressures of the hadopelagic zone of the oceans is tightly linked to the acquisition of a variant of the energy-yielding ATPases via horizontal transfer. Whereas the ATPase genealogy of neutrophilic Thaumarchaeota is congruent with their organismal genealogy inferred from concatenated conserved proteins, a common clade of V-type ATPases unites phylogenetically distinct clades of acidophilic/acid-tolerant and piezophilic/piezotolerant species. A presumptive function of pumping cytoplasmic protons at low pH is consistent with the experimentally observed increased expression of the V-ATPase in an acid-tolerant thaumarchaeote at low pH. Consistently, heterologous expression of the thaumarchaeotal V-ATPase significantly increased the growth rate of E. coli at low pH. Its adaptive significance to growth in ocean trenches may relate to pressure-related changes in membrane structure in which this complex molecular machine must function. Together, our findings reveal that the habitat expansion of Thaumarchaeota is tightly correlated with extensive horizontal transfer of atp operons

Strangeness in the proton and N*(1535)

The newest progress on the study of the strangeness in the proton and in the lowest negative parity nucleon excited state $N^*(1535)$ is reviewed. Implications on the internal quark structure of the proton, $N^*(1535)$ and other baryons are discussed. The diquark cluster picture for the 5-quark components in baryons gives a natural explanation not only to the empirical indications for a positive strangeness magnetic moment $\mu_s$ and positive strangeness radius of the proton but also the longstanding mass-reverse problem of $N^*(1535)$, $N^*(1440)$ and $\Lambda^*(1405)$ resonances as well as the unusual decay pattern of the $N^*(1535)$ resonance. Evidence for possible existence of $N^*(1535)$'s ${1/2}^-$ SU(3) nonet partners in this picture is pointed out, and suggestion is made to search for these $1/2^-$ hyperon excited states under the well known $\Sigma^*(1385)$, $\Lambda^*(1520)$ and $\Xi^*(1530)$ peaks in various reactions.Comment: 6 pages, 2 figures, Plenary talk at 18th International IUPAP Conference on Few-Body Problems in Physics August 21-26. 2006 Santos SP Brazil; to be published in Nuclear Physics

A giant retroperitoneal lymphangioma in a patient with neurofibromatosis type 1

Neurofibromatosis type 1 (NF-1) is a genetically inherited disorder that may cause skin abnormalities and tumors that form on nerve tissues. These tumors can be small or large and can occur anywhere in the body, including the brain, spinal cord, or other peripheral nerves. Retroperitoneal lymphangiomas are very rare benign malformations of the lymphatic system. About 95% lymphangiomas occur in the skin and the subcutaneous tissues of the head, neck and axillary region and the remaining 5% appear in other parts of the body such as lungs, pleura, pericardium, liver, gallbladder, kidney, and the mesentery. Herein, we report the case of a giant retroperitoneal lymphangioma in a patient with NF-1 with a review of the literature

Sasa borealis leaves extract improves insulin resistance by modulating inflammatory cytokine secretion in high fat diet-induced obese C57/BL6J mice

Obesity is considered a mild inflammatory state, and the secretion of inflammation-related cytokines rises as adipose tissue expands. Inflammatory cytokines, including tumor necrosis factor-α (TNF-α), interlukin 6 (IL-6) and monocyte-chemoattractant protein 1 (MCP-1), are modulated by adipose tissue and known to play an important role in insulin resistance which is the common characteristics of obesity related disorders. In this study we analyzed the effects of Sasa borealis leaves extract on inflammatory cytokines and insulin resistance in diet induced obese C57/BL6J mice. The obese state was induced by a high fat diet for 20 weeks and then the mice were divided into two groups; obese control group (OBC, n = 7) and experimental group (OB-SBE, n = 7). The OBC group was fed a high fat diet and the OB-SBE group was fed a high fat diet containing 5% Sasa borealis leaves extract (SBE) for 12 weeks. We also used mice fed a standard diet as a normal control (NC, n = 7). The body weight and adipose tissue weight in the OB group were significantly higher than those in the NC group. The effects of the high fat diet were reduced by SBE treatments, and the body weight and adipose tissue deposition in the OB-SBE group were significantly decreased compared to the OBC group. The OBC group showed higher serum glucose and insulin levels which resulted in a significant increase of incremental area under the curve (IAUC) and HOMA-IR than the NC group. Also, serum leptin, TNF-α, and IL-6 levels were significantly higher in the OBC group than in the NC group. In contrast, the OB-SBE group showed a reversal in the metabolic defects, including a decrease in glucose, insulin, IAUC, HOMA-IR, TNF-α, IL-6 and leptin levels. These results suggest that BSE can suppress increased weight gain and/or fat deposition induced by a high fat diet and theses effects are accompanied by modulation of the inflammatory cytokines, TNF-α and IL-6 secretion resulting in improved insulin resistance