Adults with High-functioning Autism Process Web Pages With Similar Accuracy but Higher Cognitive Effort Compared to Controls

To accommodate the needs of web users with high-functioning autism, a designer's only option at present is to rely on guidelines that: i) have not been empirically evaluated and ii) do not account for the di erent levels of autism severity. Before designing effective interventions, we need to obtain an empirical understanding of the aspects that speci c user groups need support with. This has not yet been done for web users at the high ends of the autism spectrum, as often they appear to execute tasks effortlessly, without facing barriers related to their neurodiverse processing style. This paper investigates the accuracy and efficiency with which high-functioning web users with autism and a control group of neurotypical participants obtain information from web pages. Measures include answer correctness and a number of eye-tracking features. The results indicate similar levels of accuracy for the two groups at the expense of efficiency for the autism group, showing that the autism group invests more cognitive effort in order to achieve the same results as their neurotypical counterparts

Autism detection based on eye movement sequences on the web: a scanpath trend analysis approach

This is an accepted manuscript of an article published by ACM in W4A '20: Proceedings of the 17th International Web for All Conference on 20/04/2020, available online: https://doi.org/10.1145/3371300.3383340 The accepted version of the publication may differ from the final published version.Autism diagnostic procedure is a subjective, challenging and expensive procedure and relies on behavioral, historical and parental report information. In our previous, we proposed a machine learning classifier to be used as a potential screening tool or used in conjunction with other diagnostic methods, thus aiding established diagnostic methods. The classifier uses eye movements of people on web pages but it only considers non-sequential data. It achieves the best accuracy by combining data from several web pages and it has varying levels of accuracy on different web pages. In this present paper, we investigate whether it is possible to detect autism based on eye-movement sequences and achieve stable accuracy across different web pages to be not dependent on specific web pages. We used Scanpath Trend Analysis (STA) which is designed for identifying a trending path of a group of users on a web page based on their eye movements. We first identify trending paths of people with autism and neurotypical people. To detect whether or not a person has autism, we calculate the similarity of his/her path to the trending paths of people with autism and neurotypical people. If the path is more similar to the trending path of neurotypical people, we classify the person as a neurotypical person. Otherwise, we classify her/him as a person with autism. We systematically evaluate our approach with an eye-tracking dataset of 15 verbal and highly-independent people with autism and 15 neurotypical people on six web pages. Our evaluation shows that the STA approach performs better on individual web pages and provides more stable accuracy across different pages

The hospital building as project and matter of concern: the role of representations in negotiating patient room designs and bodies

Mock-ups, scale models and drawings are ubiquitous in building design processes, circulating between various stakeholders. They contribute to the gradual evolution of design, but what else can specific material forms of representations do for the building design and project? The full-scale model of a hospital single-bed room can be different in terms of detail and medium, but in what sense might it perform different and similar functions? The mobilization of multiple forms of representations and visualizations suggest that design materialization might have several important roles to play in negotiating the building design and project, including the exposition and resolution of controversy concerning size of spaces and bodies. The paper compares the use of two different forms of representation of the same imagined space—a single-bed room in a hospital, and produced for similar purposes—to ascertain what the optimum (or minimum) spatial requirements should be to allow effective care of patients. The first representations are physical mock-ups of a single-bed room for Danish hospitals where actual medical and logistical procedures are simulated using real equipment and real people. The second is a three-dimensional augmented reality model of a single-bed room for a new hospital in the UK, using a Cave Automatic Virtual Environment where the room is reproduced virtually at one-to-one scale, and which can be explored or navigated using head-tracker technology and a joystick controller. Drawing on Latour's concepts of matters of concern and matters of fact, we compare these two cases to provide insights into the way different media produce specific senses of the design or imagined space, with consequences for on-going design work, and for the settling of controversy over the sizes of spaces and bodies

Drug Mass Transfer Mechanism, Thermodynamics, and In Vitro Release Kinetics of Antioxidant-encapsulated Zeolite Microparticles as a Drug Carrier System

The aim of the present study was to develop a new vitamin E-zeolite drug carrier system, and investigate the mass transfer mechanism of the antioxidant encapsulation and release on/from the mineral matrix by thermodynamic and kinetics sorption/desorption experiments and mathematical modelling of the experimental data. The surface, morphological and spectral characteristics of the vitamin and the zeolite were determined by Boehm titration, SEM, FTIR and UV/Vis spectrophotometric analyses. Intraparticle diffusion was not the only rate-limiting mechanism, as the mixed-order kinetics model gave the highest regression coefficient (R2) and lowest SSE, MSE, RMSE, and AICC values. The thermodynamic study confirmed the endothermic nature of the spontaneous encapsulation process and increased degrees of randomness at the solid-liquid interface. The in vitro release results were best modelled by the zero-order and sigmoidal models. The results obtained are essential for the development of innovative vitamin E-carrier systems for application in human and veterinary medicine

Strategic investment in tuberculosis control in the Republic of Bulgaria

As Bulgaria transitions away from Global Fund grant, robust estimates of the comparative impact of the various response strategies under consideration are needed to ensure sustained effectiveness of the tuberculosis (TB) programme. We tailored an established mathematical model for TB control to the epidemic in Bulgaria to project the likely outcomes of seven intervention scenarios. Under existing programmatic conditions projected forward, the country's targets for achieving TB elimination in the coming decades will not be achieved. No interventions under consideration were predicted to accelerate the baseline projected reduction in epidemiological indicators significantly. Discontinuation of the 'Open Doors' program and activities of non-governmental organisations would result in a marked exacerbation of the epidemic (increasing incidence in 2035 by 6-8% relative to baseline conditions projected forward). Changing to a short course regimen for multidrug-resistant TB (MDR-TB) would substantially decrease MDR-TB mortality (by 21.6% in 2035 relative to baseline conditions projected forward). Changing to ambulatory care for eligible patients would not affect TB burden but would be markedly cost-saving. In conclusion, Bulgaria faces important challenges in transitioning to a primarily domestically-financed TB programme. The country should consider maintaining currently effective programs and shifting towards ambulatory care to ensure program sustainability

Materialising architecture for social care: brick walls and compromises in design for later life.

This article reports on an ethnography of architectural projects for later life social care in the UK. Informed by recent debates in material studies and ‘materialities of care’ we offer an analysis of a care home project that is sensitive to architectural materials that are not normally associated with care and wellbeing. Although the care home design project we focus on in this article was never built, we found that design discussions relating to both a curved brick wall and bricks more generally were significant to its architectural ‘making’. The curved wall and the bricks were used by the architects to encode quality and values of care into their design. This was explicit in the design narrative that was core to a successful tender submitted by a consortium comprising architects, developers, contractors, and a care provider to a local authority who commissioned the care home. However, as the project developed, initial consensus for the design features fractured. Using a materialised analysis, we document the tussles generated by the curved wall and the bricks and argue that mundane building materials can be important to, and yet marginalised within, the relations inherent within an ‘architectural care assemblage.’ During the design process we saw how decisions about materials are contentious and they act as a catalyst of negotiations that compromise ‘materialities of care.

Star Architecture as Socio-Material Assemblage

Taking inspiration from new materialism and assemblage, the chapter deals with star architects and iconic buildings as socio-material network effects that do not pre-exist action, but are enacted in practice, in the materiality of design crafting and city building. Star architects are here conceptualized as part of broader assemblages of actors and practices ‘making star architecture’ a reality, and the buildings they design are considered not just as unique and iconic objects, but dis-articulated as complex crafts mobilizing skills, technologies, materials, and forms of knowledge not necessarily ascribable to architecture. Overcoming narrow criticism focusing on the symbolic order of icons as unique creations and alienated repetitions of capitalist development, the chapter’s main aim is to widen the scope of critique by bridging culture and economy, symbolism and practicality, making star architecture available to a broad, fragmented arena of (potential) critics, unevenly equipped with critical tools and differentiated experiences

POSIWID and determinism in design for behaviour change

Copyright @ 2012 Social Services Research GroupWhen designing to influence behaviour for social or environmental benefit, does designers' intent matter? Or are the effects on behaviour more important, regardless of the intent involved? This brief paper explores -- in the context of design for behaviour change -- some treatments of design, intentionality, purpose and responsibility from a variety of fields, including Stafford Beer's "The purpose of a system is what it does" and Maurice Broady's perspective on determinism. The paper attempts to extract useful implications for designers working on behaviour-related problems, in terms of analytical or reflective questions to ask during the design process

On the Usefulness of Modern Animism: Co-Creating Architecture with Soils as Ontopolitical Practice

In opposition to the general understanding of animism as an irrational religious set of beliefs, the—secular—modern animism embodied in this practice of built and grown architecture is operative. It conceives of places—ecosystems—as beings with agency that we garden with to nurture and express their resilience. It is a useful ontology for ecological practice; this architectural animism is ontopolitical; it co-creates a common world. At a recent symposium, a number of projects were presented as architectural soils and to give a voice to these earthly beings, the method was to write a letter from them to me. This first letter with the response in this article forms the beginning of an animistic correspondence. The medium places the reader in a pluriverse, in between the multiple voices of various “actants.” The text is isomorphic to the embodied dialogue of this earthy practice. It is useful both to nurture societal awareness—empathy and care—towards these fragmentary ecosystemic beings, and as research method to conceive them, and our relationship