113 research outputs found
Multiscale simulation models of Xe bubble formation in irradiated Mo
Multiscale simulation models for Xe bubble
nucleation and growth in irradiated Mo were developed
that consist Ab-initio calculations of the interatomic
potentials for the Mo and Xe-Mo systems, atomistic MD
simulations of the kinetic rate coefficients of radiation
defects, and nucleation mechanisms of Xe bubbles in Mo.
Simulations of various Xe concentrations, temperatures
and pressures were carried out. A critical concentration of
Xe atoms was determined at which the nucleation occurs
spontaneously
Hepatoprotective effect of basil (Ocimum basilicum L.) on CCl4-induced liver fibrosis in rats
The hepatoprotective effect of basil (Ocimum basilicum) extract against liver fibrosis-induced by carbon tetrachloride (CCl4) was studied in rats. Rats were allocated into five groups: Group I (control group); Group II [CCl4 group; rats were injected subcutaneously with CCl4 (1 ml/kg b.w.) twice weekly for 4 weeks (phenobarbital, 350 mg/L, was added to the drinking water throughout the experiment)]; Group III received daily oral doses of basil extract of 200 mg/kg b.w. along with CCl4 and phenobarbital for 6 weeks; Groups IV and V rats were treated with phenobarbital and CCl4 for 6 weeks then treated daily with oral dose of 200 mg/kg b.w basil extract, or by 300 mg/kg b.w dimethyl diphenyl bicarboxylate (DDB), respectively for 6 weeks. Basil-treatment significantly reduced the liver content of hydroxyproline and significantly increased the activity of hyaluronidase (HAase). The hepatic activity of superoxide dismutase (SOD) was stimulated while the lipid peroxidation was significantly reduced by the effect of basil extract. Treatment with CCl4 significantly increased the activities of transaminases [aspartate aminotransferase (AST), alanine aminotransferase (ALT)], and alkaline phosphatase (ALP). These activities were significantly decreased by basil extract. The higher levels of serum urea and creatinine in CCl4 group were significantly guarded by the protection of basil.Key words: Carbon tetrachloride, liver fibrosis, antioxidant, Ocimum basilicum, dimethyl diphenyl bicarboxylate
A New Multiscale Approach to Nuclear Fuel Simulations: Atomistic Validation of Kinetic Method
A key issue for fuel behavior codes is their sensitivity to values of various materials properties, many of which have large uncertainties or have not been measured. Kinetic mesoscale models, such as those developed at Argonne National Laboratory within the past decade, are directly comparable to data obtained from in-reactor experiments. In the present paper, a new multiscale concept is proposed that consists of using atomistic simulation methods to verify the kinetic approach. The new concept includes kinetic rate-equations for radiation damage, energetics and kinetics of defects, and gas/defect-driven swelling of fuels as a function of temperature and burnup. The quantum and classical atomistic simulation methods are applied to increase our understanding of radiation damage and defect formation and growth processes and to calculate the probabilities of elemental processes and reactions that are applicable to irradiated nuclear materials
Performance of crossbred dairy Friesian calves fed two levels of Saccharomyces cerevisiae: Intake, digestion, ruminal fermentation, blood parameters and faecal pathogenic bacteria
11 páginas, 6 tablas.The effect of feeding two levels of Saccharomyces cerevisiae on the performance of crossbred Friesian calves was investigated. Twenty-four neonatal male Friesian × Baladi calves (35·5 ± 0·25 kg of initial body weight) were randomly assigned in a completely randomized design into three experimental groups for 90 days (eight calves per group). Calves fed their diets without yeast (S. cerevisiae) were considered as Control, while the diets of other calves were supplemented daily either with 2·5 g (YL diet) or with 5 g (YH diet) of yeast per calf. Calves fed the YH diet showed increased feed intake, while dry matter and fibre digestibilities were increased in calves fed YH and YL diets. Calves fed YL and YH diets showed lower ruminal ammonia-N and higher total volatile fatty acids, acetate and propionate concentrations than Control calves. Both YH and YL calves showed increased plasma concentrations of total protein, globulin and glucose and decreased cholesterol and triglycerides concentrations. Calves' final weight and daily gain were increased with S. cerevisiae yeast supplemented diets. After 42 days of experiment, Clostridium spp., Escherichia coli and Enterobacteria spp. counts were down to undetectable levels in the faeces of calves fed S. cerevisiae additive. It could be concluded that adding S. cerevisiae to milk-fed calves increased feed utilization and improved pre-weaned calf performance and health status, reducing faecal pathogenic bacteria. Copyright © Cambridge University Press 2016.Peer reviewe
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Modeling the Nuclear Fuel Cycle
The Advanced Fuel Cycle Initiative is developing a system dynamics model as part of their broad systems analysis of future nuclear energy in the United States. The model will be used to analyze and compare various proposed technology deployment scenarios. The model will also give a better understanding of the linkages between the various components of the nuclear fuel cycle that includes uranium resources, reactor number and mix, nuclear fuel type and waste management. Each of these components is tightly connected to the nuclear fuel cycle but usually analyzed in isolation of the other parts. This model will attempt to bridge these components into a single model for analysis. This work is part of a multi-national laboratory effort between Argonne National Laboratory, Idaho National Laboratory and United States Department of Energy. This paper summarizes the basics of the system dynamics model and looks at some results from the model
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Ion beam modifications of near-surface compositions in ternary alloys
Changes in the surface and subsurface compositions of ternary alloys during elevated-temperature sputtering with inert-gas ions were investigated. Theoretically, a comprehensive kinetic model which includes all the basic processes, such as preferential sputtering, displacement mixing, Gibbsian segregation, radiation-enhanced diffusion and radiation-induced segregation, was developed. This phenomenological approach enabled to predict the effects of each individual process or of a combination of processes on the compositional modification in model alloys. Experimentally, measurements of compositional changes at the surface of a Ag-40at%Au -- 20at%Cu alloy during 3-keV Ne{sup +} bombardment at various temperatures were made, using ion scattering spectroscopy. These measurements were interpreted on the basis of the results of theoretical modeling. 8 refs., 2 figs
The suppression of MAPK/NOX/MMP signaling prompts renoprotection conferred by prenatal naproxen in weaning preeclamptic rats
Although nonsteroidal antiinflammatory drugs (NSAIDs) are frequently used for fever and pain during pregnancy, their possible interaction with perinatal renal injury induced by preeclampsia (PE) has not been addressed. Here, studies were undertaken in the N(gamma)-nitro-l-arginine methyl ester (l-NAME) PE model to assess the influence of gestational NSAIDs on renal damage in weaning dams. PE-evoked increments and decrements in urine protein and creatinine clearance, respectively, were intensified by celecoxib and weakened by diclofenac or naproxen. Naproxen also improved renal cloudy swelling, necrosis, and reduced glomerular area evoked by PE. The concomitant rises in renal expression of markers of oxidative stress (NOX2/4), extracellular matrix metaloproteinase deposition (MMP9), and prostanoids (PGE2, PGF2α, TXA2) were all more effectively reduced by naproxen compared with celecoxib or diclofenac. Western blotting showed tripled expression of mitogen-activated protein kinases (MAPKs; p-p38, p-JNK1, p-ERK1, p-ERK2) in PE kidneys that was overturned by all NSAIDs, with naproxen producing the largest drop in p-ERK2 expression. The PE-provoked elevation in renal expression of autophagic marker LC3 was reduced by naproxen and diclofenac, but not celecoxib. The data suggests superior effect for naproxen over other NSAIDs in rectifying preeclamptic renal injury and predisposing inflammatory, oxidative, autophagic, and fibrotic signals
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VISION -- A Dynamic Model of the Nuclear Fuel Cycle
The Advanced Fuel Cycle Initiative’s (AFCI) fundamental objective is to provide technology options that – if implemented – would enable long-term growth of nuclear power while improving sustainability and energy security. The AFCI organization structure consists of four areas; Systems Analysis, Fuels, Separations and Transmutations. The Systems Analysis Working Group is tasked with bridging the program technical areas and providing the models, tools, and analyses required to assess the feasibility of design and deploy¬ment options and inform key decision makers. An integral part of the Systems Analysis tool set is the development of a system level model that can be used to examine the implications of the different mixes of reactors, implications of fuel reprocessing, impact of deployment technologies, as well as potential “exit” or “off ramp” approaches to phase out technologies, waste management issues and long-term repository needs. The Verifiable Fuel Cycle Simulation Model (VISION) is a computer-based simulation model that allows performing dynamic simulations of fuel cycles to quantify infrastructure requirements and identify key trade-offs between alternatives. VISION is intended to serve as a broad systems analysis and study tool applicable to work conducted as part of the AFCI (including costs estimates) and Generation IV reactor development studies
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VISION - Verifiable Fuel Cycle Simulation of Nuclear Fuel Cycle Dynamics
The U.S. DOE Advanced Fuel Cycle Initiative’s (AFCI) fundamental objective is to provide technology options that - if implemented - would enable long-term growth of nuclear power while improving sustainability and energy security. The AFCI organization structure consists of four areas; Systems Analysis, Fuels, Separations and Transmutations. The Systems Analysis Working Group is tasked with bridging the program technical areas and providing the models, tools, and analyses required to assess the feasibility of design and deployment options and inform key decision makers. An integral part of the Systems Analysis tool set is the development of a system level model that can be used to examine the implications of the different mixes of reactors, implications of fuel reprocessing, impact of deployment technologies, as well as potential "exit" or "off ramp" approaches to phase out technologies, waste management issues and long-term repository needs. The Verifiable Fuel Cycle Simulation Model (VISION) is a computer-based simulation model that allows performing dynamic simulations of fuel cycles to quantify infrastructure requirements and identify key trade-offs between alternatives. It is based on the current AFCI system analysis tool "DYMOND-US" functionalities in addition to economics, isotopic decay, and other new functionalities. VISION is intended to serve as a broad systems analysis and study tool applicable to work conducted as part of the AFCI and Generation IV reactor development studies
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Material accountancy in an electrometallurgical Fuel Conditioning Facility
The Fuel Conditioning Facility (FCF) treats spent nuclear fuel using an electrometallurgical process that separates the uranium from the fission products, sodium thermal bond and cladding materials. Material accountancy is necessary at FCF for two reasons: first, it provides a mechanism for detecting a potential loss of nuclear material for safeguards and security; second, it provides a periodic check of inventories to ensure that processes and material are under control. By weighing material entering and leaving a process, and using sampling results to determine composition, an inventory difference (ID) results when the measured inventory is compared to the predicted inventory. The ID and its uncertainty, based on error propagation, determines the degree of assurance that an operation proceeded according to expectations. FCF uses the ID calculation in two ways: closeout, which is the ID and uncertainty for a particular operational step, and material accountancy, which determines an ID and its associated uncertainty for a material balance area through several operational steps. Material accountancy over the whole facility for a specified time period assists in detecting diversion of nuclear material. Data from depleted uranium operations are presented to illustrate the method used in FCF
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