The Effect of Donor Age on Recipient Kidney Graft Function

Purpose: End-stage renal disease (ESRD) is a highly morbid and mortal condition. Renal transplantation is the most favorable and preferred solution of this disease. Age is an important factor that can effects the success of transplantation. In this study, we investigated the effect of donor age on the outcomes of kidney transplantation. Materials and Methods: 101 ESRD patients who underwent live or cadaveric kidney transplantation were included and analyzed retrospectively in this study. We reviewed age, sex and body mass index (BMI) of the donors and age, sex, BMI, length of stay, estimated glomerular filtration rate (eGFR) and serum creatinine measurements of the recipients were recorded. Recipient serum creatinine levels were determined at intervals up to 18 months after transplantation. Results: Donors were divided into 3 groups according to age (50 years (n:34). There was no statistically significant difference between the groups in terms of donor's gender, BMI, living/cadaveric ratio, and recipient's gender, age, and BMI (p>0.05). Length of hospital stay of recipients whose donor <40 years old were statistically significantly lower compared to other age groups (p:0.001). From the 1st month to the 18th month, a statistically significant decrease in GFR and an increase in serum creatinine were observed as the donor age increased (p<0.05). Conclusion: Donor age is an important factor for the graft survival and for the allocation procedures it should be kept in mind

“The Lolelaplap (Marshall Islands) in Us: Sailing West to East (Ralik→Ratak) to These Our Atolls (Aelon Kein Ad) Ad Jolet Jen Anij (Our Blessed Inheritance from God)”

This paper discusses the expansion of Oceania through a Marshallese indigenous lens as a focal point. It explains that decolonizing methodologies allows reclaiming of space for mental liberation and reassurement of constitutional rights. It highlights similar occurrences of decolonization practices meeting resistance in the 21st century all while strengthening the human right argument that no human deserves any less than their fellow human brothers and sisters. It argues that an indigenous imagery can only be viewed through an indigenous lens where the researches’ level of purity is retained and unfiltered. It nevertheless argues that Marshallese ethnolinguistics reveal the same cultural practices in America, Judeo-Christianity, and Oceania thus dictating the reality that “we are the same not withstanding one stays here and one there (Bedbedjin Bedbedjen, Bedbedjinma wot Kwe)”. It further explains the importance in these similarities and how Marshallese spirituality predates introduced American Judeo-Christianity despite the latter attempting to marginalize the former. It concludes by stating that Marshallese contributions on the global stage are rooted in that culture of love (IaKwe) which is echoed by the custom(s) revealing the significance of Marshallese validation academically, spiritually, economically, & socially to prevent institutionalized discrimination. This paper ends stating that the agency to know one’s self and how one should fit in the world, is a human right in itself and Marshallese are entitled to this sense of self worth through knowing thy self by thy self where real thinking takes place in one’s own mind as we all live our own lives

Impact of opioid-free analgesia on pain severity and patient satisfaction after discharge from surgery: multispecialty, prospective cohort study in 25 countries

Background: Balancing opioid stewardship and the need for adequate analgesia following discharge after surgery is challenging. This study aimed to compare the outcomes for patients discharged with opioid versus opioid-free analgesia after common surgical procedures.Methods: This international, multicentre, prospective cohort study collected data from patients undergoing common acute and elective general surgical, urological, gynaecological, and orthopaedic procedures. The primary outcomes were patient-reported time in severe pain measured on a numerical analogue scale from 0 to 100% and patient-reported satisfaction with pain relief during the first week following discharge. Data were collected by in-hospital chart review and patient telephone interview 1 week after discharge.Results: The study recruited 4273 patients from 144 centres in 25 countries; 1311 patients (30.7%) were prescribed opioid analgesia at discharge. Patients reported being in severe pain for 10 (i.q.r. 1-30)% of the first week after discharge and rated satisfaction with analgesia as 90 (i.q.r. 80-100) of 100. After adjustment for confounders, opioid analgesia on discharge was independently associated with increased pain severity (risk ratio 1.52, 95% c.i. 1.31 to 1.76; P &lt; 0.001) and re-presentation to healthcare providers owing to side-effects of medication (OR 2.38, 95% c.i. 1.36 to 4.17; P = 0.004), but not with satisfaction with analgesia (beta coefficient 0.92, 95% c.i. -1.52 to 3.36; P = 0.468) compared with opioid-free analgesia. Although opioid prescribing varied greatly between high-income and low- and middle-income countries, patient-reported outcomes did not.Conclusion: Opioid analgesia prescription on surgical discharge is associated with a higher risk of re-presentation owing to side-effects of medication and increased patient-reported pain, but not with changes in patient-reported satisfaction. Opioid-free discharge analgesia should be adopted routinely

Unusual Location of Primary Hydatid Cyst: Soft Tissue Mass in the Parapharyngeal Region

Hydatid cyst is a cyclozoonotic infection caused by the cestode Echinococcus granulosus. Hydatid cyst in the head and neck region is very rare, even in countries where echinococcus infestation is endemic. We report the case of a 17-year-old male patient presenting with a hydatid cyst in the parapharyngeal and neck region. There was no pulmonary or hepatic involvement. The definitive therapy comprised excision of the cystic mass and postoperative medical treatment

Adaçayı (Salvia Officinalis) Bitkisinin Farklı Nem Düzeylerinde Fiziko-Mekanik Özelliklerinin Belirlenmesi

Adaçayı (Salvia Officinalis) ülkemizde yaygın olarak üretilen tibbi aromatik bitkiler içerisinde yer almaktadır. Adaçayı (Salvia Officinalis) ile ilgili tarımsal mekanizasyon uygulamaları yeterli değildir. Bu uygulamaları arttırmak için bitkiye ait fiziko-mekanik özelliklerin bilinmesi gerekmektedir. Bu çalışmada, adaçayı (Salvia Officinalis) bitkisinin üç farklı nem düzeyinde (%8.4, %11.5% ve %16.2 (k.b)), boyutları, projeksiyon alanı yapraklarının saptan kopma kuvveti, yaprak/sap oranı, uçucu yağ miktarı gibi bazı fiziko-mekanik özellikleri belirlenmiştir. Bu özellikler adaçayı (Salvia Officinalis) bitkisi için harmanlama ve ayırma düzenlerinin geliştirilmesinde önemli özelliklerdir. Araştırılan özelliklerin çoğu nem artışına bağlı olarak artmaktadır. Uçucu yağ içeriği nem düzeyinin artmasına bağlı olarak azalmıştır. Nem içeriğinin adaçayının fiziko-mekanik özellikleri üzerine etkisi önemli bulunmuştur. Yaprak kopma kuvveti 4.3 N ve 6.5 N arasında değişmektedir

Congenital hairy polyp of the soft palate

Hairy polyp is an unusual developmental malformation that is most frequently seen as a pedunculated tumor in the neonate. They are benign lesions containing elements of both ectodermal and mesodermal origin. The symptoms of hairy polyps relate both to their location and their size. Larger lesions produce symptoms due to feeding difficulties and airway obstruction while smaller lesions cause intermittent symptoms resulting from a ball-valve type of obstruction

Microstructural Evolution and Mechanical Properties in Directionally Solidified Sn-10.2 Sb Peritectic Alloy at a Constant Temperature Gradient

WOS: 000374233300015The Sn-10.2 Sb (mass fraction) peritectic alloy was prepared using a vacuum melting furnace and a hot filling furnace. The samples were directionally solidified upwards at steady state conditions with a constant temperature gradient (G = 4.5 +/- 0.2 K. mm(-1)) under different growth velocities (V = 13.3-266.7 mu m. s(-1)) in a Bridgman-type directional solidification apparatus. The effects of the growth velocity (V) on the dendritic spacings were investigated. Primary dendrite arm spacing (PDAS) of a phase in directionally solidified Sn-10.2 Sb peritectic alloy was measured on the longitudinal and transverse sections of 4 mm diameter cylindrical samples. Secondary dendrite arm spacing (SDAS) was measured on the longitudinal section. The experimental results show that the measured PDAS (lambda(IL),lambda(IT)) and SDAS (lambda(2)) decrease with increasing growth velocity. The dependence of PDAS, SDAS, microhardness (HV) and compressive strength (sigma(c)) on the growth velocity were determined by using a linear regression analysis. The experimental results were compared with the previous experimental results and the results of the experimental models.Erciyes University Scientific Research Project Unit [FBT-07-18]This project was financially supported by the Erciyes University Scientific Research Project Unit under contract No: FBT-07-18

Tongue Reduction in Beckwith-Wiedemann Syndrome With CO2 Laser

Beckwith-Wiedemann syndrome is a congenital syndrome with some anomaly in overgrowth. Most common manifestations are exomphalos, macroglossia, gigantism, and visceromegaly. Overgrowth in tongue's size caused clinical symptoms such as dysphagia, speech disorder, strong in chewing, upper-airway obstruction, and psychological problems with appearance. Cold surgical techniques are commonly used in treating macroglossia. We presented tongue reduction with laser and its early result on a child with Beckwith-Wiedemann syndrome for macroglossia