Gamma-ray burst early optical afterglows: implications for the initial Lorentz factor and the central engine

Early optical afterglows have been observed from GRB 990123, GRB 021004, and GRB 021211, which reveal rich emission features attributed to reverse shocks. It is expected that Swift will discover many more early afterglows. Here we investigate in a unified manner both the forward and the reverse external shock emission components, and introduce a straightforward recipe for directly constraining the initial Lorentz factor of the fireball using early optical afterglow data. The scheme is largely independent of the shock microphysics. We identify two types of combinations of the reverse and forward shock emission, and explore their parameter regimes. We also discuss a possible diagnostic for magnetized ejecta. There is evidence that the central engine of GRB 990123 is strongly magnetized.Comment: emulateapj style, 6 pages, 1 figure. Expanded version accepted for publication in ApJ Part

Life Tables of Bactrocera cucurbitae (Coquillett) (Diptera: Tephritidae): with a Mathematical Invalidation for Applying the Jackknife Technique to the Net Reproductive Rate

Life table data for the melon fly, Bactrocera cucurbitae (Coquillett), reared on cucumber (Cucumis sativus L.) were collected under laboratory and simulated field conditions. Means and standard errors of life table parameters were estimated for two replicates using the jackknife technique. At 25ºC, the intrinsic rates of increase (_r_) found for the two replicates were 0.1354 and 0.1002 day-1, and the net reproductive rates (_R_~0~) were 206.3 and 66.0 offspring, respectively. When the cucumbers kept under simulated field conditions were covered with leaves, the _r_ and _R_~0~ for the two replicates were 0.0935 and 0.0909 day-1, 17.5 and 11.4 offspring, respectively. However, when similar cucumbers were left uncovered, the _r_ and _R_~0~ for the two replicates were 0.1043 and 0.0904 day-1, and 27.7 and 10.1 offspring, respectively. Our results revealed that considerable variability between replicates in both laboratory and field conditions is possible; this variability should be taken into consideration in data collection and application of life tables. Mathematical analysis has demonstrated that applying the jackknife technique results in unrealistic pseudo-_R_~0~ and overestimation of its variance. We suggest that the jackknife technique should not be used for the estimation of variability of _R_~0~

Mechanistic Basis for Control of Early Embryonic Development by a 5’ tRNA Fragment

Ancestral environmental conditions can instruct offspring development, although the mechanism(s) underlying such transgenerational epigenetic inheritance is unclear. In murine models focused on paternal dietary effects, we and others have identified tRNA fragments (tRFs) in mature sperm as potential carriers of epigenetic information. In our search for molecular targets of specific tRFs, we observed that altering the level of 5’-tRF Glycine-GCC (tRF-GG) in mouse embryonic stem cells (mESCs) and preimplantation embryos modulates the expression of the endogenous retrovirus MERV-L and genes regulated by MERV-L. Intriguingly, transient derepression of MERV-L is associated with totipotency of two-cell stage embryos and a subset of two-cell-like mESCs. Here, I reveal the mechanistic basis for tRF-GG regulation of MERV-L. I show that tRF-GG supports the production of numerous small nuclear RNAs associated with the Cajal body, in mouse and human embryonic stem cells. In particular, tRF-GG modulates the levels of U7 snRNA to ensure an adequate supply of histone proteins. This in turn safeguards heterochromatin-mediated transcriptional repression of MERV-L elements. Importantly, tRF-GG effects on histone mRNA levels, activity of a histone 3’UTR reporter, and expression of MERV-L associated transcripts can all be suppressed by appropriate manipulation of U7 RNA levels. I also show that hnRNPF and H bind directly to tRF-GG, and display a stark overlap of in vivo functions to tRF-GG. Together, this data uncovers a conserved mechanism for a 5’ tRNA fragment in the fine-tuning of a regulatory cascade to modulate global chromatin organization during pre-implantation development

Understanding molecular representations in machine learning: The role of uniqueness and target similarity

The predictive accuracy of Machine Learning (ML) models of molecular properties depends on the choice of the molecular representation. Based on the postulates of quantum mechanics, we introduce a hierarchy of representations which meet uniqueness and target similarity criteria. To systematically control target similarity, we rely on interatomic many body expansions, as implemented in universal force-fields, including Bonding, Angular, and higher order terms (BA). Addition of higher order contributions systematically increases similarity to the true potential energy and predictive accuracy of the resulting ML models. We report numerical evidence for the performance of BAML models trained on molecular properties pre-calculated at electron-correlated and density functional theory level of theory for thousands of small organic molecules. Properties studied include enthalpies and free energies of atomization, heatcapacity, zero-point vibrational energies, dipole-moment, polarizability, HOMO/LUMO energies and gap, ionization potential, electron affinity, and electronic excitations. After training, BAML predicts energies or electronic properties of out-of-sample molecules with unprecedented accuracy and speed

Early photon-shock interaction in stellar wind: sub-GeV photon flash and high energy neutrino emission from long GRBs

For gamma-ray bursts (GRBs) born in a stellar wind, as the reverse shock crosses the ejecta, usually the shocked regions are still precipitated by the prompt MeV \gamma-ray emission. Because of the tight overlapping of the MeV photon flow with the shocked regions, the optical depth for the GeV photons produced in the shocks is very large. These high energy photons are absorbed by the MeV photon flow and generate relativistic e^\pm pairs. These pairs re-scatter the soft X-ray photons from the forward shock as well as the prompt \gamma-ray photons and power detectable high energy emission, significant part of which is in the sub-GeV energy range. Since the total energy contained in the forward shock region and the reverse shock region are comparable, the predicted sub-GeV emission is independent on whether the GRB ejecta are magnetized (in which case the reverse shock IC and synchrotron self-Compton emission is suppressed). As a result, a sub-GeV flash is a generic signature for the GRB wind model, and it should be typically detectable by the future {\em Gamma-Ray Large Area Telescope} (GLAST). Overlapping also influence neutrino emission. Besides the 10^{15} \sim 10^{17} eV neutrino emission powered by the interaction of the shock accelerated protons with the synchrotron photons in both the forward and reverse shock regions, there comes another $10^{14}$eV neutrino emission component powered by protons interacting with the MeV photon flow. This last component has a similar spectrum to the one generated in the internal shock phase, but the typical energy is slightly lower.Comment: 7 pages, accepted for publication in Ap

Spin interference and Fano effect in electron transport through a mesoscopic ring side-coupled with a quantum dot

We investigate the electron transport through a mesoscopic ring side-coupled with a quantum dot(QD) in the presence of Rashba spin-orbit(SO) interaction. It is shown that both the Fano resonance and the spin interference effects play important roles in the electron transport properties. As the QD level is around the Fermi energy, the total conductance shows typical Fano resonance line shape. By applying an electrical gate voltage to the QD, the total transmission through the system can be strongly modulated. By threading the mesoscopic ring with a magnetic flux, the time-reversal symmetry of the system is broken, and a spin polarized current can be obtained even though the incident current is unpolarized.Comment: 5 pages, 5 figure

A comprehensive analysis of Swift/XRT data: I. Apparent spectral evolution of GRB X-ray tails

An early steep decay component following the prompt GRBs is commonly observed in {\em Swift} XRT light curves, which is regarded as the tail emission of the prompt gamma-rays. Prompted by the observed strong spectral evolution in the tails of GRBs 060218 and 060614, we present a systematic time-resolved spectral analysis for the {\em Swift} GRB tails detected between 2005 February and 2007 January. We select a sample of 44 tails that are bright enough to perform time-resolved spectral analyses. Among them 11 tails are smooth and without superimposing significant flares, and their spectra have no significant temporal evolution. We suggest that these tails are dominated by the curvature effect of the prompt gamma-rays due to delay of propagation of photons from large angles with respect to the line of sight . More interestingly, 33 tails show clear hard-to-soft spectral evolution, with 16 of them being smooth tails directly following the prompt GRBs,while the others being superimposed with large flares. We focus on the 16 clean, smooth tails and consider three toy models to interpret the spectral evolution. The curvature effect of a structured jet and a model invoking superposition of the curvature effect tail and a putative underlying soft emission component cannot explain all the data. The third model, which invokes an evolving exponential spectrum, seems to reproduce both the lightcurve and the spectral evolution of all the bursts, including GRBs 060218 and 060614. More detailed physical models are called for to understand the apparent evolution effect.Comment: 13 pages in emulateapj style,6 figures, 1 table, expanded version, matched to published version, ApJ, 2007, in press. This is the first paper of a series. Paper II see arXiv:0705.1373 (ApJ,2007, in press