Diagnostic Capability of Peripapillary Retinal Volume Measurements in Glaucoma

Purpose: To determine the diagnostic capability of spectral domain optical coherence tomography peripapillary retinal volume (RV) measurements. Materials and Methods: A total of 156 patients, 89 primary open-angle glaucoma and 67 normal subjects, were recruited. Spectral domain optical coherence tomography peripapillary RV was calculated for 4 quadrants using 3 annuli of varying scan circle diameters: outer circumpapillary annuli of circular grids 1, 2, and 3 (OCA1, OCA2, OCA3). Area under the receiver operating characteristic curves and pairwise comparisons of receiver operating characteristic (ROC) curves were performed to determine which quadrants were best for diagnosing primary open-angle glaucoma. The pairwise comparisons of the best ROC curves for RV and retinal nerve fiber layer (RNFL) were performed. The artifact rates were analyzed. Results: Pairwise comparisons showed that the smaller annuli OCA1 and OCA2 had better diagnostic performance than the largest annulus OCA3 (P<0.05 for all quadrants). OCA1 and OCA2 had similar diagnostic performance, except for the inferior quadrant which was better for OCA1 (P=0.0033). The pairwise comparisons of the best ROC curves for RV and RNFL were not statistically significant. RV measurements had lower rates of artifacts at 7.4% while RNFL measurements had higher rates at 42.9%. Conclusions: Peripapillary RV measurements have excellent ability for diagnosing not only glaucoma patients but also a subset of early glaucoma patients. The inferior quadrant of peripapillary annulus OCA1 demonstrated the best diagnostic capability for both glaucoma and early glaucoma. The diagnostic ability of RV is comparable with that of RNFL parameters in glaucoma but with lower artifact rates. © 2017 Wolters Kluwer Health, Inc. All rights reserved

A small place, by Jamaica Kincaid: envisioning literary tourism in Antigua

This work departs from a reading of the novelistic essay A small place (1988), by Jamaica Kincaid, to analyse the representation of the tourism industry and of tourists in Antigua (the author's birthplace). From there, we present Kincaid's text as ?tourist literature? (Hendrix, 2014), also aiming to contribute to the examination of tourism-centred literary texts. Within the context of literature and tourism studies as well as comparative studies, this paper examines Kincaid's literary text in order to consider the promotion of literary tourism in Antigua. This example is then considered in light of recent contributions from literary tourism, space production, community-based tourism, mass tourism as well as responsible and sustainable tourism. Literary heritage as a resource for the tourism industry could bring tourists and locals closer and conspire to break down barriers between the largely dark-skinned hosts and the white tourists in Antigua

Poverty and Well-being in Post-Apartheid South Africa: An Overview of Data, Outcomes and Policy

WP 2006-03 January 2006This is an overview of poverty and well-being in the first decade of post-apartheid South Africa. It is an introduction to a volume that brings together some of the most prominent academic research done on this topic for the 10-year review process in South Africa. This overview highlights three key aspects of the picture that the detailed research paints. First, data quality and comparability has been a constant issue in arriving at a consensus among analysts on the outcomes for households and individuals in postapartheid South Africa. Second, while the outcomes on unemployment, poverty and inequality are indeed bad, the outcomes on social indicators and access to public services are much more encouraging. Third, the prospects for rapid and sustained economic growth, without which poverty and well-being cannot be addressed in the long run, are themselves negatively affected by increasing inequality, poverty and unemployment

Trends in poverty and inequality since the political transition

Using a constructed data series and another data series based on the All Media and Products surveys (AMPS), this paper explores trends in poverty and income distribution over the post-transition period. To steer clear of an unduly optimistic conclusion, assumptions are chosen that would tend to show the least decline in poverty. Whilst there were no strong trends in poverty for the period 1995 to 2000, both data series show a considerable decline in poverty after 2000, particularly in the period 2002-2004. Poverty dominance testing shows that this decline is independent of the poverty line chosen or whether the poverty headcount, the poverty ratio or the poverty severity ratio are used as measure. We find likely explanations for this strong and robust decline in poverty in the massive expansion of the social grant system as well as possibly in improved job creation in recent years. Whilst the collective income of the poor (using our definition of poverty) was only R27 billion in 2000, the grants (in constant 2000 Rand values) have expanded by R22 billion since. Even if the grants were not well targeted at the poor (and in the past they have been), a large proportion of this spending must have reached the poor, thus leaving little doubt that poverty must have declined substantially

Magnetic trapping of atomic nitrogen (N14) and cotrapping of NH (X Σ-3)

We observe magnetic trapping of atomic nitrogen (N14) and cotrapping of ground-state imidogen (N14 H, X Σ-3). Both are loaded directly from a room-temperature beam via buffer gas cooling. We trap approximately 1× 1011 N14 atoms at a peak density of 5× 1011 cm-3 at 550 mK. The 12±4 s 1/e lifetime of atomic nitrogen in the trap is consistent with a model for loss of atoms over the edge of the trap in the presence of helium buffer gas. Cotrapping of N14 and N14 H is accomplished, with 108 NH trapped molecules at a peak density of 108 cm-3. © 2008 The American Physical Society

Determinants of foreign direct investment in Ghana

Produced in association with Ghana UniversityAvailable from British Library Document Supply Centre-DSC:m01/27805 / BLDSC - British Library Document Supply CentreSIGLEGBUnited Kingdo

Diagnostic Capability of Peripapillary Retinal Volume Measurements in Glaucoma.

PURPOSE: To determine the diagnostic capability of spectral domain optical coherence tomography peripapillary retinal volume (RV) measurements. MATERIALS AND METHODS: A total of 156 patients, 89 primary open-angle glaucoma and 67 normal subjects, were recruited. Spectral domain optical coherence tomography peripapillary RV was calculated for 4 quadrants using 3 annuli of varying scan circle diameters: outer circumpapillary annuli of circular grids 1, 2, and 3 (OCA1, OCA2, OCA3). Area under the receiver operating characteristic curves and pairwise comparisons of receiver operating characteristic (ROC) curves were performed to determine which quadrants were best for diagnosing primary open-angle glaucoma. The pairwise comparisons of the best ROC curves for RV and retinal nerve fiber layer (RNFL) were performed. The artifact rates were analyzed. RESULTS: Pairwise comparisons showed that the smaller annuli OCA1 and OCA2 had better diagnostic performance than the largest annulus OCA3 (P<0.05 for all quadrants). OCA1 and OCA2 had similar diagnostic performance, except for the inferior quadrant which was better for OCA1 (P=0.0033). The pairwise comparisons of the best ROC curves for RV and RNFL were not statistically significant. RV measurements had lower rates of artifacts at 7.4% while RNFL measurements had higher rates at 42.9%. CONCLUSIONS: Peripapillary RV measurements have excellent ability for diagnosing not only glaucoma patients but also a subset of early glaucoma patients. The inferior quadrant of peripapillary annulus OCA1 demonstrated the best diagnostic capability for both glaucoma and early glaucoma. The diagnostic ability of RV is comparable with that of RNFL parameters in glaucoma but with lower artifact rates