1001 Caras : aprender a través del arte en el aula de 3 años

Este artículo recoge la experiencia en un Centro Educativo de la Sierra de Madrid, llevada a cabo con un grupo de primero de Educación Infantil (3 años).\ud Se trata de un proyecto globalizado enmarcado dentro de una pedagogía\ud activa en el que todas las áreas se entremezclan: expresión oral, educación artística, conocimiento del medio¿\ud El punto de partida es un cuadro de la segunda mitad del siglo XVIII: «Retrato\ud femenino»atribuido a un seguidor de Antón Van Dyck.\ud El proyecto se estructura en tres momentos: antes, durante y después de la visita al Gabinete Artístico donde se encuentra el cuadro escogido.This article shows an experience developed in a school located in the Sierra de Madrid area with children aged three (1st grade Early Children Education). The experience is a global project framed within an active pedagogy, in which all areas are entwined: oral expression, arts education, environment knowledge,\ud etc. The main resource has been a painting from the 2nd half of the 18th century titled «Feminine Portrait», attributed to a follower of the Flemish painter Anton Van\ud Dyck. The project is divided into three stages: before, during, and after the visit to an\ud art gallery, named El Gabinete Artístico, where the chosen painting is shown

Momentum and energy preserving integrators for nonholonomic dynamics

In this paper, we propose a geometric integrator for nonholonomic mechanical systems. It can be applied to discrete Lagrangian systems specified through a discrete Lagrangian defined on QxQ, where Q is the configuration manifold, and a (generally nonintegrable) distribution in TQ. In the proposed method, a discretization of the constraints is not required. We show that the method preserves the discrete nonholonomic momentum map, and also that the nonholonomic constraints are preserved in average. We study in particular the case where Q has a Lie group structure and the discrete Lagrangian and/or nonholonomic constraints have various invariance properties, and show that the method is also energy-preserving in some important cases.Comment: 18 pages, 6 figures; v2: example and figures added, minor correction to example 2; v3: added section on nonholonomic Stoermer-Verlet metho

Non-polymeric Microspheres for the Therapeutic Use of Estrogens: An Innovative Technology

Non-polymeric microspheres are stable-shaped particles constituted by crystalline organic compounds. This technology allows controlled release of parental products that has its prime value on estrogen therapy. The structure is a non-polymeric crystalline microsphere that uses a low solubility fatty acid, cholesterol as a carrier. Cholesterol is a waxy lipid, a substance that is insoluble in water and has been recognized as safe as excipient by FDA for the manufacturing of drugs. Cholesterol is a lipid present in the cell membrane and subcellular organelles of tissues and serves as the building block for all steroid hormones including cortisol, aldosterone, estrogen, and testosterone; therefore, this fatty acid provides better biocompatibility than polymers. The use of cholesterol as a low solubility carrier was used to develop a first of its kind, parental HT product for the management of menopausal symptoms carrying estrogen microspheres in an aqueous suspension, which would allow an extended estrogen release maintaining plasmatic therapeutic concentrations. Estradiol doses would be up to 30 times lower than that provided by oral and transdermal routes fulfilling current recommendations regarding the use of a low dose and the nonoral route. Both intramuscular monthly administered formulations of E/P non-polymeric microspheres had favorable pharmacokinetic and safety profiles, suggesting this route as an interesting, novel, and suitable way of treating menopause-related symptoms

Diversity of large and medium mammals in Juchitan, Isthmus of Tehuantepec, Oaxaca, Mexico

El istmo de Tehuantepec en Oaxaca, México, es una de las regiones más importantes del país desde el punto de vista zoogeográfico, ya que alberga una gran cantidad de especies endémicas neotropicales. Entre septiembre de 2007 y agosto de 2008, se realizó un muestreo de mamíferos de talla mediana y grande en el municipio de Juchitán, y comparamos su diversidad en dos zonas con distintos niveles de impacto antropogénico definido de acuerdo con las estimaciones de las actividades humanas, la densidad de ganado y la degradación del hábitat. Se obtuvieron 167 registros de 18 especies, con una representatividad del 79% según el modelo de acumulación de especies en ambas zonas. La mayor riqueza de especies y la diversidad alfa se registraron en la zona conservada, mientras que la zona perturbada presenta la mitad de la diversidad encontrada en la zona conservada. Se observó un fuerte intercambio de especies entre ambas zonas. Dos especies, Urocyon cinereoargenteus (n = 52) y Didelphis virginiana (n = 42), tuvieron el mayor número de registros. En ambas zonas, la mayor abundancia relativa se observó durante la época de lluvias. La degradación del hábitat y las actividades humanas al parecer afectan a la diversidad de especies de mamíferos en la región.La diversidad de los mamíferos de talla grande y mediana en Juchitán, istmo de Tehuantepec, Oaxaca, México El istmo de Tehuantepec en Oaxaca, México, es una de las regiones más importantes del país desde el punto de vista zoogeográfico, ya que alberga una gran cantidad de especies endémicas neotropicales. Entre septiembre de 2007 y agosto de 2008, se realizó un muestreo de mamíferos de talla mediana y grande en el municipio de Juchitán, y comparamos su diversidad en dos zonas con distintos niveles de impacto antropogénico definido de acuerdo con las estimaciones de las actividades humanas, la densidad de ganado y la degradación del hábitat. Se obtuvieron 167 registros de 18 especies, con una representatividad del 79% según el modelo de acumulación de especies en ambas zonas. La mayor riqueza de especies y la diversidad alfa se registraron en la zona conservada, mientras que la zona perturbada presenta la mitad de la diversidad encontrada en la zona conservada. Se observó un fuerte intercambio de especies entre ambas zonas. Dos especies, Urocyon cinereoargenteus (n = 52) y Didelphis virginiana (n = 42), tuvieron el mayor número de registros. En ambas zonas, la mayor abundancia relativa se observó durante la época de lluvias. La degradación del hábitat y las actividades humanas al parecer afectan a la diversidad de especies de mamíferos en la región.The Isthmus of Tehuantepec in Oaxaca, Mexico, is one of the country’s most important regions from a zoogeographical perspective due to the large number of endemic Neotropical species found there. Between September 2007 and August 2008, we sampled medium–sized and large mammals in the Juchitan municipality and compared their diversity in two areas with distinct levels of anthropogenic impact, defined according to estimates of human activities, livestock density and habitat degradation, We obtained 167 records of 18 species, with a 79% representation according to species accumulation models in both areas. The highest species richness and alpha diversity were recorded in the preserved area, whereas the disturbed area exhibited half the diversity found in the preserved area. A high interchange of species was also observed between zones. The two species with the largest number of records were Urocyon cinereoargenteus (n = 52) and Didelphis virginiana (n = 42). In both areas, the highest relative abundance occurred during the rainy season. Habitat degradation and human activities seem to affect the diversity of mammal species in the region

Reliable and randomized data distribution strategies for large scale storage systems

The ever-growing amount of data requires highly scalable storage solutions. The most flexible approach is to use storage pools that can be expanded and scaled down by adding or removing storage devices. To make this approach usable, it is necessary to provide a solution to locate data items in such a dynamic environment. This paper presents and evaluates the Random Slicing strategy, which incorporates lessons learned from table-based, rule-based, and pseudo-randomized hashing strategies and is able to provide a simple and efficient strategy that scales up to handle exascale data. Random Slicing keeps a small table with information about previous storage system insert and remove operations, drastically reducing the required amount of randomness while delivering a perfect load distribution.Peer ReviewedPostprint (author’s final draft