1-Meth­oxy-3-o-tolyl­bicyclo­[2.2.2]oct-5-ene-2,2-dicarbonitrile

In the title compound, C18H18N2O, the cyclo­hexene and cyclo­hexane rings of the bicyclo­[2.2.2]oct-5-ene unit adopt distorted boat conformations. In the crystal, mol­ecules exist as C—H⋯N hydrogen-bonded centrosymmetric R 2 2(14) dimers, which are further linked by C—H⋯π inter­actions

N-Cyano-7α-methoxy­carbonyl-6,14-endo-ethenotetra­hydro­northebaine

In the title compound (systematic name: methyl 17-cyano-3,6-dimeth­oxy-4,5α-ep­oxy-6,14-endo-ethenomorphinan-7-carboxyl­ate), C23H24N2O5, the dihydro­furan ring adopts a twist conformation, while the piperidine ring is in a chair conformation. The benzene-fused cyclo­hexene ring adopts an envelope conformation. An intra­molecular C—H⋯O hydrogen bond is observed. Inter­molecular C—H⋯N and C—H⋯O hydrogen bonds form C(5) chains along the a and b axes, respectively, and together they form a three-dimensional network

Dimethyl trans-3-(4-bromo­phen­yl)-2-methyl­isoxazolidine-4,5-dicarboxyl­ate

In the title compound, C14H16BrNO5, the isoxazolidine ring adopts an envelope conformation, with the N atom at the flap. In the crystal, inter­molecular C—H⋯N and C—H⋯O hydrogen bonds generate R 3 3(18) ring motifs which are fused into a ribbon-like structure extending along the b axis

9-(4-Methoxy­phen­yl)-3,3,6,6-tetra­methyl-3,4,6,7-tetra­hydro-2H-xanthene-1,8(5H,9H)-dione

In the mol­ecule of the title compound, C24H28O4, the three six-membered rings of the xanthene system are not planar, having envelope, boat and envelope conformations. In the crystal structure, C—H⋯O hydrogen bonds link the mol­ecules, generating centrosymmetric R 2 2(12), R 4 4(28) and R 2 2(16) ring motifs and forming a three-dimensional network

2-Methyl-3-(5-methyl-2-thien­yl)-5-phenyl­perhydro­pyrrolo[3,4-d]isoxazole-4,6-dione

In the mol­ecule of the title compound, C17H16N2O3S, the phenyl ring is oriented with respect to the thio­phene and succinimide rings at dihedral angles of 88.08 (3) and 57.81 (3)°, respectively; the dihedral angle between the thio­phene and succinimide rings is 35.69 (3)°. The isoxazole ring adopts an envelope conformation with the N atom at the flap position. In the crystal structure, inter­molecular C—H⋯O hydrogen bonds link the mol­ecules into infinite chains along the b axis. Weak C—H⋯π inter­actions may further stabilize the structure

7α-Methoxy­carbonyl-6,7,8,14-tetra­hydro-6,14-endo-ethenothebaine

In the mol­ecule of the title compound, C23H27NO5, the furan ring adopts an envelope conformation. Intra­molecular C—H⋯O inter­actions result in the formation of S(5) and S(6) motifs. In the crystal structure, weak inter­molecular C—H⋯O hydrogen bonds link the mol­ecules through C(6) and C(8) chains along the [100] and [010] directions, generating a two-dimensional network

4-[2-(2,2-Dimethyl-4,6-dioxo-1,3-dioxan-5-yl­idene)hydrazin-1-yl]benzo­nitrile

In the title compound, C13H11N3O4, the dioxane ring adopts an envelope conformation with the C atom bonded to the dimethyl group in the flap position [deviation = 0.613 (1) Å]. The nitrile group and the attached benzene ring are roughly coplanar [maximum deviation = 0.087 (1) Å]. An intra­molecular N—H⋯O hydrogen bond involving the hydrazinyl group generates an S(6) ring. The N—N and C—N bond lengths indicate that the compound may be a mixture of the azo and hydrazone tautomeric forms but the presence of the N-bound H atom supports the hydrazone form. The crystal structure is stabilized by weak inter­molecular C—H⋯O, C—H⋯N and C—H⋯π inter­actions

www.mdpi.org/molecules A Novel Synthesis of Bromobenzenes Using Molecular Bromine

Abstract: Certain substituted bromobenzenes have been synthesized in acceptable yields using a novel Sandmeyer type reaction. The reactions are relatively quick and possibly proceed via a radical mechanism