Sonography and Magnetic Resonance Imaging Characteristics of Testicular Adrenal Rest Tumors

Summary Background: The aim of this study was to describe the gray-scale and color Doppler ultrasonography (US) and magnetic resonance (MR) imaging features of testicular adrenal rest tumors (TART) in patients with congenital adrenal hyperplasia. Material/Methods Forty-one patients with congenital adrenal hyperplasia were evaluated by gray-scale and color Doppler ultrasonography. Totally eighteen adrenal rest tumors in 9 patients were diagnosed TART on US and MR imaging. Gray-scale and color Doppler US and MR findings of the patients were documented. Results: A total of eighteen masses were evaluated in nine patients. The mean age of these patients was 14.3±4.5 (range 10.1–23.3) years. US revealed hypoechoic lesions around the mediastinum testis with hypervascularity dispersing in ten patients and hypovascularity in two patients. In six patients, the lesions were hyperechoic with poor vascularity. Lesions exhibited homogeneous (n=8) and heterogeneous (n=10). Testicular microlithiasis was present in 4 of 9 patients with TART. Doppler ultrasound showed normal testicular vessels passing through the mass which were undisturbed, not displaced and not change in caliber. MRI features were the following: all lesions were hypointense on T2- and hyperintense (n=12) and isointense (n=6) on T1-weighted images. All masses revealed homogeneous contrast enhancement on postcontrast T1-weighted images. Conclusions: Ultrasonography and MRI are good methods for detecting and monitoring TART. US is the first preferable modality because it is quick and cheap than MRI. Bilateral mostly hypoechoic lesions depicted around the mediastinum testis with no mass effect is highly suggestive for the diagnosis of testicular adrenal rest tissues on ultrasonography. Normal testicular vessels coursing through the lesions undisturbed and not change in caliber is described specific for this kind of tumors

Outcomes of high-risk breast lesions diagnosed using image-guided core needle biopsy: results from a multicenter retrospective study

PURPOSEThe clinical management of high-risk lesions using image-guided biopsy is challenging. This study aimed to evaluate the rates at which such lesions were upgraded to malignancy and identify possible predictive factors for upgrading high-risk lesions.METHODSThis retrospective multicenter analysis included 1.343 patients diagnosed with high-risk lesions using an image-guided core needle or vacuum-assisted biopsy (VAB). Only patients managed using an excisional biopsy or with at least one year of documented radiological follow-up were included. For each, the Breast Imaging Reporting and Data System (BI-RADS) category, number of samples, needle thickness, and lesion size were correlated with malignancy upgrade rates in different histologic subtypes. Pearson’s chi-squared test, the Fisher–Freeman–Halton test, and Fisher’s exact test were used for the statistical analyses.RESULTSThe overall upgrade rate was 20.6%, with the highest rates in the subtypes of intraductal papilloma (IP) with atypia (44.7%; 55/123), followed by atypical ductal hyperplasia (ADH) (38.4%; 144/375), lobular neoplasia (LN) (12.7%; 7/55), papilloma without atypia (9.4%; 58/611), flat epithelial atypia (FEA) (8.7%; 10/114), and radial scars (RSs) (4.6%; 3/65). There was a significant relationship between the upgrade rate and BI-RADS category, number of samples, and lesion size Lesion size was the most predictive factor for an upgrade in all subtypes.CONCLUSIONADH and atypical IP showed considerable upgrade rates to malignancy, requiring surgical excision. The LN, IP without atypia, pure FEA, and RS subtypes showed lower malignancy rates when the BI-RADS category was lower and in smaller lesions that had been adequately sampled using VAB. After being discussed in a multidisciplinary meeting, these cases could be managed with follow-up instead of excision

“Residual calcifications after neoadjuvant chemotherapy: Comparison of the accuracies of MG and MRI in predicting pathological residual tumor according to molecular subtypes”

“Residualcalcificationsafterneoadjuvantchemotherapy:Comparisonoftheaccuraciesof MGandMRIinpredictingpathologicalresidualtumoraccordingtomolecularsubtypes

A great mimicker of Bone Secondaries: Brown Tumors, presenting with a Degenerative Lumber Disc like pain

This report presents an adult patient suffering from sacroiliitis like low back pain, lumbosacral radiculopathy and elbow swelling. Multimodality imaging revealed multiple lytic bone lesions located in supra acetabular iliac bone, sacrum, and distal end of radius. Painful numerous lesions due to the extension to the articular surfaces are not expected for Brown tumors. Less than ten cases with multiple Brown tumor due to primary hyperparathyroidism has been reported. Although Brown tumors are mostly diagnosed incidentally, this case would awake the physicians about rheumatological symptoms in the presentation of Brown tumors. Since Brown tumors are non-touch bone lesions that are expected to regress after parathyroid adenoma removal, it is important to distinguish Brown tumors from the giant cell tumors

DİŞ HEKİMLİĞİ ÖĞRENCİLERİ ARASINDA PREKLİNİK DERSLERİ SIRASINDA MEYDANA GELEN MESLEKİ YARALANMALARIN ARAŞTIRILMASI

Diş hekimliği fakültelerinde, klinik öncesi eğitimi sırasında öğrencilerin yaşadığı mesleki yaralanmaları raporetmeleri, bu raporlara göre problemlerin tespit edilmesi ve bu konularda öğrencilerin eğitilmesi son dereceönemlidir. Bu nedenle, bu çalışmada diş hekimliği öğrencilerinin klinik öncesi eğitim dersleri sırasında maruz kaldıkları farklı yaralanmaların belirlenmesi amaçlandı. Birinci, ikinci ve üçüncü sınıf diş hekimliği öğrencilerine, klinik öncesi eğitim dersleri boyunca yaşadıkları yaralanmaların türü, yaralanma sayısı ve hangiklinik öncesi eğitim dersinde meydana geldiği ile ilgiliisimsiz anketleri doldurmaları istendi. Anket bulgularının tanımlayıcı istatistikleri yapıldı. Öğrencilerin %63.4’ü en az bir kez klinik öncesi eğitim derslerindeyaralandıklarını bildirdi. Öğrencilerin % 8’i ise beş defadan fazla yaralandığını bildirdi. En sık karşılaşılanyaralanmanın, ispirto ocağı ile meydana gelen yanıkdurumu olduğu, en fazla yaralanmanın ise endodontiklinik öncesi eğitim derslerinde meydana geldiği tespitedildi. Öğrencilerin %12.1’inin hepatit B aşısı olduğubelirlendi. Öğrencilerin sadece % 14.3’ünün yaralanmasonrasında durumu sorumlu öğretim üyesine bildirdiğigörüldü. Bu çalışmanın bulgularına göre, klinik öncesieğitim sırasında, öğrencilerde yaralanma görülme sıklığı yüksek bulundu. Yaralanmayı bildirme oranı ise oldukça düşüktür. Bu bilgilerin elde edilmesi, gelecektebu tür yaralanmaların sayısını azaltmak adına gerekliönlemlerin alınması ve öğrencilerin bu konu ile ilgilifarkındalıklarının artırılması için yararlı olabilir.Anahtar kelimeler: Diş hekimliği öğrencileri, eğitim,meslek yaralanmaları.&nbsp;</p