176 research outputs found

    Who Drops out? A Study of Secondary School Dropouts in Connecticut

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    The purpose of the study was to investigate the relationships between the dropout pattern and student characteristics such as gender, ethnicity and grade level among exited students from grade 7 to grade 12. The study included 57,709 students from grades 7-12 in the 2006-2007 school year in Connecticut. A logistic regression analysis was conducted to examine demographic factors related to student dropout pattern. This study provides empirical evidence of identifying secondary school students in Connecticut who were more likely to drop out. Identifying the groups of high risk students would help practitioners and policy makers to develop prevention programs or make interventions to reduce student attrition at the early stage, and thus, to close the achievement gap among these groups

    Remarks on the Qin-Ma Parametrization of Quark Mixing Matrix

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    Recently, Qin and Ma (QM) have advocated a new Wolfenstein-like parametrization of the quark mixing matrix based on the triminimal expansion of the Cabibbo-Kobayashi-Maskawa (CKM) parametrization. The CP-odd phase in the QM parametrization is around 9090^\circ just as that in the CKM parametrization. We point out that the QM parametrization can be readily obtained from the Wolfenstein parametrization after appropriate phase redefinition for quark fields and that the phase δ\delta in both QM and CKM parametrizations is related to the unitarity angles α\alpha, β\beta and γ\gamma, namely, δ=β+γ\delta= \beta+\gamma or πα\pi-\alpha. We show that both QM and Wolfenstein parametrizations can be deduced from the CKM and Chau-Keung-Maiani ones. By deriving the QM parametrization from the Fritzsch-Xing (FX) parametrization of the quark mixing matrix, we find that the phase of the FX form is in the vicinity of 270-270^\circ and hence sinδ1\sin\delta\approx 1. We discuss the seeming discrepancy between the Wolfenstein and QM parametrizations at the high order of λVus\lambda\approx |V_{us}|.Comment: 8 pages, a shortened version accepted by PL

    Vortex-line liquid phases: Longitudinal superconductivity in the lattice London model

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    We study the vortex-line lattice and liquid phases of a clean type-II superconductor by means of Monte Carlo simulations of the lattice London model. Motivated by a recent controversy regarding the presence, within this model, of a vortex-liquid regime with longitudinal superconducting coherence over long length scales, we directly compare two different ways to calculate the longitudinal coherence. For an isotropic superconductor, we interpret our results in terms of a temperature regime within the liquid phase in which longitudinal superconducting coherence extends over length scales larger than the system thickness studied. We note that this regime disappears in the moderately anisotropic case due to a proliferation, close to the flux-line lattice melting temperature, of vortex loops between the layers.Comment: 8 pages, Revtex, with eps figures. To appear in Phys. Rev.

    Mass measurements of neutron-deficient Y, Zr, and Nb isotopes and their impact on rp and νp nucleosynthesis processes

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    © 2018 The Authors. Published by Elsevier B.V. This manuscript is made available under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International licence (CC BY-NC-ND 4.0). For further details please see: https://creativecommons.org/licenses/by-nc-nd/4.0/Using isochronous mass spectrometry at the experimental storage ring CSRe in Lanzhou, the masses of 82Zr and 84Nb were measured for the first time with an uncertainty of ∼10 keV, and the masses of 79Y, 81Zr, and 83Nb were re-determined with a higher precision. The latter are significantly less bound than their literature values. Our new and accurate masses remove the irregularities of the mass surface in this region of the nuclear chart. Our results do not support the predicted island of pronounced low α separation energies for neutron-deficient Mo and Tc isotopes, making the formation of Zr–Nb cycle in the rp-process unlikely. The new proton separation energy of 83Nb was determined to be 490(400) keV smaller than that in the Atomic Mass Evaluation 2012. This partly removes the overproduction of the p-nucleus 84Sr relative to the neutron-deficient molybdenum isotopes in the previous νp-process simulations.Peer reviewe

    Unitary limit and quantum interference effect in disordered two-dimensional crystals with nearly half-filled bands

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    Based on the self-consistent TT-matrix approximation, the quantum interference (QI) effect is studied with the diagrammatic technique in weakly-disordered two-dimensional crystals with nearly half-filled bands. In addition to the usual 0-mode cooperon and diffuson, there exist π\pi-mode cooperon and diffuson in the unitary limit due to the particle-hole symmetry. The diffusive π\pi-modes are gapped by the deviation from the exactly-nested Fermi surface. The conductivity diagrams with the gapped π\pi-mode cooperon or diffuson are found to give rise to unconventional features of the QI effect. Besides the inelastic scattering, the thermal fluctuation is shown to be also an important dephasing mechanism in the QI processes related with the diffusive π\pi-modes. In the proximity of the nesting case, a power-law anti-localization effect appears due to the π\pi-mode diffuson. For large deviation from the nested Fermi surface, this anti-localization effect is suppressed, and the conductivity remains to have the usual logarithmic weak-localization correction contributed by the 0-mode cooperon. As a result, the dc conductivity in the unitary limit becomes a non-monotonic function of the temperature or the sample size, which is quite different from the prediction of the usual weak-localization theory.Comment: 21 pages, 4 figure

    Highly connected 3D chromatin networks established by an oncogenic fusion protein shape tumor cell identity.

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    Cell fate transitions observed in embryonic development involve changes in three-dimensional genomic organization that provide proper lineage specification. Whether similar events occur within tumor cells and contribute to cancer evolution remains largely unexplored. We modeled this process in the pediatric cancer Ewing sarcoma and investigated high-resolution looping and large-scale nuclear conformation changes associated with the oncogenic fusion protein EWS-FLI1. We show that chromatin interactions in tumor cells are dominated by highly connected looping hubs centered on EWS-FLI1 binding sites, which directly control the activity of linked enhancers and promoters to establish oncogenic expression programs. Conversely, EWS-FLI1 depletion led to the disassembly of these looping networks and a widespread nuclear reorganization through the establishment of new looping patterns and large-scale compartment configuration matching those observed in mesenchymal stem cells, a candidate Ewing sarcoma progenitor. Our data demonstrate that major architectural features of nuclear organization in cancer cells can depend on single oncogenes and are readily reversed to reestablish latent differentiation programs

    Charmless BsPP,PV,VVB_s\to PP, PV, VV Decays Based on the six-quark Effective Hamiltonian with Strong Phase Effects II

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    We provide a systematic study of charmless BsPP,PV,VVB_s \to PP, PV, VV decays (PP and VV denote pseudoscalar and vector mesons, respectively) based on an approximate six-quark operator effective Hamiltonian from QCD. The calculation of the relevant hard-scattering kernels is carried out, the resulting transition form factors are consistent with the results of QCD sum rule calculations. By taking into account important classes of power corrections involving "chirally-enhanced" terms and the vertex corrections as well as weak annihilation contributions with non-trivial strong phase, we present predictions for the branching ratios and CP asymmetries of BsB_s decays into PP, PV and VV final states, and also for the corresponding polarization observables in VV final states. It is found that the weak annihilation contributions with non-trivial strong phase have remarkable effects on the observables in the color-suppressed and penguin-dominated decay modes. In addition, we discuss the SU(3) flavor symmetry and show that the symmetry relations are generally respected

    The chromatin landscape of primary synovial sarcoma organoids is linked to specific epigenetic mechanisms and dependencies.

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    Synovial sarcoma (SyS) is an aggressive mesenchymal malignancy invariably associated with the chromosomal translocation t(X:18; p11:q11), which results in the in-frame fusion of the BAF complex gene SS18 to one of three SSX genes. Fusion of SS18 to SSX generates an aberrant transcriptional regulator, which, in permissive cells, drives tumor development by initiating major chromatin remodeling events that disrupt the balance between BAF-mediated gene activation and polycomb-dependent repression. Here, we developed SyS organoids and performed genome-wide epigenomic profiling of these models and mesenchymal precursors to define SyS-specific chromatin remodeling mechanisms and dependencies. We show that SS18-SSX induces broad BAF domains at its binding sites, which oppose polycomb repressor complex (PRC) 2 activity, while facilitating recruitment of a non-canonical (nc)PRC1 variant. Along with the uncoupling of polycomb complexes, we observed H3K27me3 eviction, H2AK119ub deposition and the establishment of de novo active regulatory elements that drive SyS identity. These alterations are completely reversible upon SS18-SSX depletion and are associated with vulnerability to USP7 loss, a core member of ncPRC1.1. Using the power of primary tumor organoids, our work helps define the mechanisms of epigenetic dysregulation on which SyS cells are dependent

    Phenomenological Analysis of B->PP Decays with QCD Factorization

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    In this paper, we study nonleptonic charmless B decays to two light pseudoscalar mesons within the frame of QCD factorization, including the contributions from the chirally enhanced power corrections and weak annihilation. Predictions for the CP-averaged branching ratios and CP-violating asymmetries are given. Within the reasonable range of the parameters, we find that our predictions for the branching ratios of B -> PP are consistent with the present experimental data. But because of the logarithmic divergences at the endpoints in the hard spectator scatterings and weak annihilation, there are still large uncertainties in these predictions.Comment: 34 pages, 5 figures. to appear in PR
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