687 research outputs found
Effect of a poloxamer 407-based thermosensitive gel on minimization of thermal injury to diaphragm during microwave ablation of the liver.
AIM: To assess the insulating effect of a poloxamer 407 (P407)-based gel during microwave ablation of liver adjacent to the diaphragm.
METHODS: We prepared serial dilutions of P407, and 22.5% (w/w) concentration was identified as suitable for ablation procedures. Subsequently, microwave ablations were performed on the livers of 24 rabbits (gel, saline, control groups, n = 8 in each). The P407 solution and 0.9% normal saline were injected into the potential space between the diaphragm and liver in experimental groups. No barriers were applied to the controls. After microwave ablations, the frequency, size and degree of thermal injury were compared histologically among the three groups. Subsequently, another 8 rabbits were injected with the P407 solution and microwave ablation was performed. The levels of alanine aminotransferase (ALT), aspartate aminotransferase (AST), blood urea nitrogen (BUN) and creatinine (Cr) in serum were tested at 1 d before microwave ablation and 3 and 7 d after operation.
RESULTS: In vivo ablation thermal injury to the adjacent diaphragm was evaluated in the control, saline and 22.5% P407 gel groups (P = 0.001-0.040). However, there was no significant difference in the volume of ablation zone among the three groups (P \u3e 0.05). Moreover, there were no statistical differences among the preoperative and postoperative gel groups according to the levels of ALT, AST, BUN and Cr in serum (all P \u3e 0.05).
CONCLUSION: Twenty-two point five percent P407 gel could be a more effective choice during microwave ablation of hepatic tumors adjacent to the diaphragm. Further studies for clinical translation are warranted
Aptamer–drug conjugate: targeted delivery of doxorubicin in a HER3 aptamer-functionalized liposomal delivery system reduces cardiotoxicity
Evidence of a resonant structure in the cross section between 4.05 and 4.60 GeV
The cross section of the process for
center-of-mass energies from 4.05 to 4.60~GeV is measured precisely using data
samples collected with the BESIII detector operating at the BEPCII storage
ring.
Two enhancements are clearly visible in the cross section around 4.23 and
4.40~GeV.
Using several models to describe the dressed cross section yields stable
parameters for the first enhancement, which has a mass of 4228.6 \pm 4.1 \pm
6.3 \un{MeV}/c^2 and a width of 77.0 \pm 6.8 \pm 6.3 \un{MeV}, where the
first uncertainties are statistical and the second ones are systematic.
Our resonant mass is consistent with previous observations of the
state and the theoretical prediction of a molecule.
This result is the first observation of associated with an
open-charm final state.
Fits with three resonance functions with additional , ,
, , or a new resonance, do not show significant
contributions from either of these resonances. The second enhancement is not
from a single known resonance. It could contain contributions from
and other resonances, and a detailed amplitude analysis is required to better
understand this enhancement
Study of and and
We study the decays of and to the final states
and based on a single
baryon tag method using data samples of
and events collected with
the BESIII detector at the BEPCII collider. The decays to
are observed for the first time. The
measured branching fractions of and
are in good agreement with, and much
more precise, than the previously published results. The angular parameters for
these decays are also measured for the first time. The measured angular decay
parameter for , , is found to be negative, different to the other
decay processes in this measurement. In addition, the "12\% rule" and isospin
symmetry in the and and
systems are tested.Comment: 11 pages, 7 figures. This version is consistent with paper published
in Phys.Lett. B770 (2017) 217-22
Measurements of absolute hadronic branching fractions of baryon
Using of collisions recorded at
with the BESIII detector, we report first measurements
of absolute hadronic branching fractions of Cabibbo-favored decays of the
baryon with a double-tag technique. A global least-square
fitter is utilized to improve the measured precision. Among the measurements
for twelve decay modes, the branching fraction for
is determined to be
, where the first uncertainty is statistical and the
second is systematic. In addition, the measurements of the branching fractions
of the other eleven Cabbibo-favored hadronic decay modes are significantly
improved
Observation of near = 4.42 and 4.6 GeV
Based on data samples collected with the BESIII detector operating at the
BEPCII storage ring at center-of-mass energies 4.4 GeV, the
processes are observed for the first
time. With an integrated luminosity of near 4.42
GeV, a significant signal is found, and the cross section is
measured to be (20.9 \pm 3.2 \pm 2.5)\pb. With near 4.6 GeV, a clear signal is seen, and the cross section is
measured to be (9.5 \pm 2.1 \pm 1.3) \pb, while evidence is found for an
signal. The first errors are statistical and the second are
systematic. Due to low luminosity or low cross section at other energies, no
significant signals are observed. In the cross section, an
enhancement is seen around 4.42 GeV. Fitting the cross section
with a coherent sum of the Breit-Wigner function and a phase space
term, the branching fraction is
obtained to be of the order of .Comment: 7 pages, 3 figure
Improved measurement of the absolute branching fraction of
By analyzing 2.93 fb of data collected at GeV with the
BESIII detector, we measure the absolute branching fraction , which is consistent with previous measurements within
uncertainties but with significantly improved precision. Combining the Particle
Data Group values of , , and the lifetimes of the and
mesons with the value of measured in this work, we determine the following ratios of
partial widths: and .Comment: 9 pages; 8 figure
Determination of the number of events with inclusive decays
A measurement of the number of events collected with the BESIII
detector in 2009 and 2012 is performed using inclusive decays of the .
The number of events taken in 2009 is recalculated to be
, which is in good agreement with the previous
measurement, but with significantly improved precision due to improvements in
the BESIII software. The number of events taken in 2012 is determined
to be . In total, the number of events
collected with the BESIII detector is measured to be , where the uncertainty is dominated by systematic effects and the
statistical uncertainty is negligible.Comment: 10 pages, 6 figure
Observation of radiative decay and evidence for
A search for radiative decays of the -wave spin singlet charmonium
resonance is performed based on events
collected with the BESIII detector operating at the BEPCII storage ring. Events
of the reaction channels and are
observed with a statistical significance of and ,
respectively, for the first time. The branching fractions of and are measured to be
and , respectively, where the first errors are
statistical and the second are systematic uncertainties.Comment: 7 pages, 2 figure
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