388 research outputs found
Textures and Vortices in d-Wave Fermi Condensates in Atomic Gases
Fundamental properties of superfluids with d-wave pairing symmetry are
investigated theoretically. We consider neutral atomic Fermi gases in a
harmonic trap, the Cooper pairing being produced by a Feshbach resonance via a
d-wave interaction channel. A Ginzburg-Landau (GL) functional is constructed
which is symmetry constrained for five component order parameters (OPs). We
find stable OP textures and vortices for all the three phases which are known
to be the energy minimum of the GL functional; the ferromagnetic, polar and
cyclic phases both at rest and under rotation. In particular, we touch upon the
stability conditions for a non-Abelian fractional 1/3-vortex in the cyclic
phase under rotation. It is proposed how to create the intriguing 1/3-vortex
experimentally in atomic gases via optical means.Comment: 10 pages, 6 figure
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Murine obscurin and Obsl1 have functionally redundant roles in sarcolemmal integrity, sarcoplasmic reticulum organization, and muscle metabolism.
Biological roles of obscurin and its close homolog Obsl1 (obscurin-like 1) have been enigmatic. While obscurin is highly expressed in striated muscles, Obsl1 is found ubiquitously. Accordingly, obscurin mutations have been linked to myopathies, whereas mutations in Obsl1 result in 3M-growth syndrome. To further study unique and redundant functions of these closely related proteins, we generated and characterized Obsl1 knockouts. Global Obsl1 knockouts are embryonically lethal. In contrast, skeletal muscle-specific Obsl1 knockouts show a benign phenotype similar to obscurin knockouts. Only deletion of both proteins and removal of their functional redundancy revealed their roles for sarcolemmal stability and sarcoplasmic reticulum organization. To gain unbiased insights into changes to the muscle proteome, we analyzed tibialis anterior and soleus muscles by mass spectrometry, uncovering additional changes to the muscle metabolism. Our analyses suggest that all obscurin protein family members play functions for muscle membrane systems
Patient Awareness and Approval for an Opt-Out Genomic Biorepository
Aim: In this study, we sought to assess patient awareness and perceptions of an opt-out biorepository. Materials & methods: We conducted exit interviews with adult patients and parents of pediatric patients having their blood drawn as part of their clinical care at Vanderbilt University Medical Center (TN, USA). Results: 32.9% of all patients and parents of pediatric patients report having heard of the opt-out biorepository, while 92.4% approve of this research effort based on a brief description. Awareness that leftover blood could be used for research increased among adult patients during the study period, from 34.3 to 50.0%. Conclusion: These findings will inform ongoing assessments of the suitability of opt-out and opt-in methods as alternatives to written informed consent for inclusion in a biorepository
Optical Technologies for UV Remote Sensing Instruments
Over the last decade significant advances in technology have made possible development of instruments with substantially improved efficiency in the UV spectral region. In the area of optical coatings and materials, the importance of recent developments in chemical vapor deposited (CVD) silicon carbide (SiC) mirrors, SiC films, and multilayer coatings in the context of ultraviolet instrumentation design are discussed. For example, the development of chemically vapor deposited (CVD) silicon carbide (SiC) mirrors, with high ultraviolet (UV) reflectance and low scatter surfaces, provides the opportunity to extend higher spectral/spatial resolution capability into the 50-nm region. Optical coatings for normal incidence diffraction gratings are particularly important for the evolution of efficient extreme ultraviolet (EUV) spectrographs. SiC films are important for optimizing the spectrograph performance in the 90 nm spectral region. The performance evaluation of the flight optical components for the Solar Ultraviolet Measurements of Emitted Radiation (SUMER) instrument, a spectroscopic instrument to fly aboard the Solar and Heliospheric Observatory (SOHO) mission, designed to study dynamic processes, temperatures, and densities in the plasma of the upper atmosphere of the Sun in the wavelength range from 50 nm to 160 nm, is discussed. The optical components were evaluated for imaging and scatter in the UV. The performance evaluation of SOHO/CDS (Coronal Diagnostic Spectrometer) flight gratings tested for spectral resolution and scatter in the DGEF is reviewed and preliminary results on resolution and scatter testing of Space Telescope Imaging Spectrograph (STIS) technology development diffraction gratings are presented
Determining the Extent of Pioneer Mangrove Acidification on Intertidal Oyster Reefs
The Indian River Lagoon (IRL) stretches 251 kilometers along Florida’s east coast and is one of the most biodiverse estuaries in North America. Mosquito Lagoon, the northernmost portion of the IRL, is home to mangroves and intertidal oyster reefs that provide numerous ecosystem services. These two habitats are overlapping as climate change drives mangroves poleward. Scientists have documented mangrove expansion and the transition of oyster reef habitat to mangrove islands. Past studies have shown large, adult mangrove stands drive soil acidification. The goal of this study was to understand if stand-alone, or pioneer, Rhizophora mangle (red mangroves) and Avicennia germinans (black mangroves) acidify intertidal Crassostrea virginica (eastern oyster) reef sediment. We collected porewater (i.e., water within sediment) and measured pH with a portable pH meter. Porewater pH was sampled from 0 to 1 meter away from pioneer mangroves in 20 cm increments. Closest to the mangrove trunk, reef sediment pH was significantly more acidic (mean pH of 7.18 for R. mangle and 7.02 for A. germinans) compared to oyster reef-only control areas with a mean pH of 7.44 (p-value \u3c 0.001 for both mangrove species). By 1 meter away from the mangrove trunk, the pH for both mangrove species was no longer significantly different from the control areas (p-value = 1.0), indicating mangrove-driven acidification has a localized effect on oyster reef sediments. Acidification weakens oyster shells, and by understanding the extent of mangroves’ acidic effects on oyster reefs, resource managers can use this information to protect declining oyster reef habitat
Atlanta Youth Count 2018 Community Report: The Prevalence of Sex and Labor Trafficking Among Homeless Youth in Metro Atlanta
The 2018 Atlanta Youth Count (AYC18) was a follow-up study to the 2015 Atlanta Youth Count and Needs Assessment (AYCNA), expanded in 2018 to specifically address sex and labor trafficking among youth experiencing homelessness in metro Atlanta. The goals of this project were to: 1) provide metro Atlanta service providers, policymakers, and youth advocates with practical information on the size, nature, and needs of the homeless, precariously housed, and runaway youth in our community who are involved in various forms of sex and labor trafficking; 2) collect information that can be used to develop and refine policies, programs, and interventions to help these youth in our community; and 3) encourage a community-wide dialogue about the needs and social determinants of youth homelessness and human trafficking. This study was funded by the National Institute of Justice and was conducted in partnership with local service providers, advocates, researchers, and students.
This document is the official public Human Trafficking Report and provides an overview of the study methodology and key findings, including the research team’s official estimates of the prevalence of trafficking among homeless youth in metro Atlanta, as well as a description of key characteristics of the population derived from the survey data collected. Members of the research team are continuing to analyze and use the data to improve the public’s and policymakers’ understanding of youth homelessness and trafficking and to guide community - based efforts to improve services for these young people
Generation of vortices and observation of Quantum Turbulence in an oscillating Bose-Einstein Condensate
We report on the experimental observation of vortex formation and production
of tangled vortex distribution in an atomic BEC of Rb-87 atoms submitted to an
external oscillatory perturbation. The oscillatory perturbations start by
exciting quadrupolar and scissors modes of the condensate. Then regular
vortices are observed finally evolving to a vortex tangle configuration. The
vortex tangle is a signature of the presence of a turbulent regime in the
cloud. We also show that this turbulent cloud has suppression of the aspect
ratio inversion typically observed in quantum degenerate bosonic gases during
free expansion.Comment: to appear in JLTP - QFS 200
Treatment of Septic arthritis of the coxofemoral joint in 12 foals
Objective:
To describe the clinical signs, surgical treatment, and outcome of septic arthritis of the coxofemoral joint in foals.
Study Design:
Retrospective clinical study.
Sample Population:
Foals (n = 12) with confirmed sepsis of the coxofemoral joint.
Methods:
Lameness was localized to the coxofemoral joint based on physical examination. Sepsis was confirmed by cytological analysis of synovial fluid obtained under ultrasonographic guidance, during general anesthesia or standing sedation. Intra-articular analgesia was used as an adjunct diagnostic modality in 2 foals. Surgical lavage of the affected joint was performed via arthroscopy or needle lavage, with repeated lavage performed in 7 foals.
Results:
Synovial fluid contained 4.4 to 173 × 109/L white blood cells (WBCs), and 38-63 g/L total protein. Cultures were positive in 10/12 foals. Isolated organisms included Salmonella spp., Streptococcus spp., Rhodococcus spp., Enterococcus spp., Escherichia spp., Staphylococcus spp., Acinetobacter spp., Methicillin-resistant Staphylococcus aureus and Bacillus spp. Ten foals were discharged from hospital (83%). One of these was euthanized 15 days later due to chronic intestinal salmonellosis and renal failure, and 9 foals survived with no residual lameness detected 1 year after discharge from hospital.
Conclusions:
Sepsis of the coxofermoral joint can be effectively treated with a combination of arthroscopic lavage and the use of systemic and local antimicrobials
Effects of three oral analgesics on postoperative pain following root canal preparation: a controlled clinical trial
Aim To compare the effects of single doses of three oral medications on postoperative pain following instrumentation of root canals in teeth with irreversible pulpitis. Methodology In this double‐blind clinical trial, 100 patients who had anterior or premolar teeth with irreversible pulpitis without any signs and symptoms of acute or chronic apical periodontitis and moderate to severe pain were divided by balanced block random allocation into four groups of 25 each, a control group receiving a placebo medication, and three experimental groups receiving a single dose of either Tramadol (100 mg), Novafen (325 mg of paracetamol, 200 mg ibuprofen and 40 mg caffeine anhydrous) or Naproxen (500 mg) immediately after the first appointment where the pulp was removed, and the canals were fully prepared. The intensity of pain was scored based on 10‐point VAS before and after treatment for up to 24 h postoperatively. Data were submitted to repeated analysis of variance. Results At the 6, 12 and 24 h postoperative intervals after drug administration, the intensity of pain was significantly lower in the experimental groups than in the placebo group ( P 0.05). Conclusion A single oral dose of Naproxen, Novafen and Tramadol taken immediately after treatment reduced postoperative pain following pulpectomy and root canal preparation of teeth with irreversible pulpitis.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/89451/1/j.1365-2591.2011.01950.x.pd
Optical dipole traps and atomic waveguides based on Bessel light beams
We theoretically investigate the use of Bessel light beams generated using
axicons for creating optical dipole traps for cold atoms and atomic
waveguiding. Zeroth-order Bessel beams can be used to produce highly elongated
dipole traps allowing for the study of one-dimensional trapped gases and
realization of a Tonks gas of impentrable bosons. First-order Bessel beams are
shown to be able to produce tight confined atomic waveguides over centimeter
distances.Comment: 20 pages, 5 figures, to appear in Phys. Rev.
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