Proactive, Not Reactive: Evolving Elm Management in the Nation\u27s Capital

Washington D.C. is home to many historic elm corridors managed in close partnership between numerous urban forestry stakeholders. In recent years, the city\u27s elms have been used as part of streetscape revitalization initiatives due to their quick-growing nature. The use of a popular Ulmus americana cultivar, Princeton, has brought about notable challenges in urban tree management. From the nursery to the tree box and even ten years later, these elms have required consistent attention in order to adequately train the form to achieve a sustainable canopy while minimizing structural defects. Two such plantings are explored, both with hand-selected trees from the same stock and nursery. These serve to highlight the differences between traditional urban forestry plantings and those under constant and careful scrutiny

Efficiency studies in dairy farming, Bulletin, no. 275

The Bulletin is a publication of the New Hampshire Agricultural Experiment Station, College of Life Sciences and Agriculture, University of New Hampshire, Durham, New Hampshire

Criminal and Noncriminal Psychopathy: The Devil is in the Detail

Brooks, NS ORCiD: 0000-0003-1784-099XPsychopathy is prevalent and problematic in criminal populations, but is also found to be present in noncriminal populations. In 1992, Robert Hare declared that psychopaths may also “be found in the boardroom”, which has since been followed by an interest in the issue of noncriminal, or even successful, psychopathy. In this chapter, the paradox of criminal and noncriminal psychopathy is discussed with specific attention given to the similarities and differences that account for psychopathic personality across contexts. That psychopathy is a condition typified by a constellation of traits and behaviours requires wider research across diverse populations, and thus the streams of research related to criminal and noncriminal psychopathy are presented and the implications of these contrasting streams are explored

Sea level: measuring the bounding surfaces of the ocean

The practical need to understand sea level along the coasts, such as for safe navigation given the spatially variable tides, has resulted in tide gauge observations having the distinction of being some of the longest instrumental ocean records. Archives of these records, along with geological constraints, have allowed us to identify the century-scale rise in global sea level. Additional data sources, particularly satellite altimetry missions, have helped us to better identify the rates and causes of sea level rise and the mechanisms leading to spatial variability in the observed rates. Analysis of all of the data reveals the need for long-term and stable observation systems to assess accurately the regional changes as well as to improve our ability to estimate future changes in sea level. While information from many scientific disciplines is needed to understand sea level change, this paper focuses on contributions from geodesy and the role of the ocean’s bounding surfaces: the sea surface and the Earth’s crust

Vertical land movements and sea level changes on South Georgia, South Atlantic Ocean: Results from 7 years of geodetic and oceanographic observations on a remote island

South Georgia Island in the South Atlantic Ocean, is a small remote land mass that supports various ground-based instrumental observations (Global Navigation Satellite System (GNSS), tide gauge, meteorological and seismic) in an otherwise largely under sampled oceanic region. Moreover, the South Atlantic Ocean plays an important role in global ocean circulation, con-necting the deep thermohaline circulation of the North Atlantic and Indian Oceans, whilst also linking to the Antarctic Circumpolar Current in the South, where the lack of continental barriers allows a free exchange of water between the major ocean basins. Hence, South Georgia po-tentially lies within a region susceptible to climatic changes before these can be felt further afield. In 2013 and 2014 a total of five GNSS stations were installed covering the area of the main island (approximately 170 x 50 km) with two of those being located close to the King Edward Point (KEP) Research Station and the GLOSS tide gauge (ID 187). Furthermore, precise levelling campaigns in 2013, 2014, 2017 and 2020 supported the analysis of local ground instabilities near the tide gauge. Through these activities the tide gauge datum within the Permanent Ser-vice for Mean Sea Level (PSMSL) has been established, which in turn, makes the derived KEP mean sea level (MSL) record highly valuable for long-term studies and satellite altimetry cali-brations. In this study, we will present the vertical land movement estimates from seven years of GNSS observations, five precise levelling campaigns, and will discuss their impact on the sea level record from the KEP tide gauge and nearby satellite altimetry sea surface heights. Our results confirm uplift all over South Georgia Island while the area at KEP and particularly the jetty with tide gauge are subsiding relative to the rest of the island. Using this information we correct the MSL record for the vertical land movements and investigate its signals together with those from nearby satellite altimetry tracks

Human and murine clonal CD8+ T cell expansions arise during tuberculosis because of TCR selection

The immune system can recognize virtually any antigen, yet T cell responses against several pathogens, including Mycobacterium tuberculosis, are restricted to a limited number of immunodominant epitopes. The host factors that affect immunodominance are incompletely understood. Whether immunodominant epitopes elicit protective CD8+ T cell responses or instead act as decoys to subvert immunity and allow pathogens to establish chronic infection is unknown. Here we show that anatomically distinct human granulomas contain clonally expanded CD8+ T cells with overlapping T cell receptor (TCR) repertoires. Similarly, the murine CD8+ T cell response against M. tuberculosis is dominated by TB10.44-11-specific T cells with extreme TCRß bias. Using a retro genic model of TB10.44-11-specific CD8+ Tcells, we show that TCR dominance can arise because of competition between clonotypes driven by differences in affinity. Finally, we demonstrate that TB10.4-specific CD8+ T cells mediate protection against tuberculosis, which requires interferon-? production and TAP1-dependent antigen presentation in vivo. Our study of how immunodominance, biased TCR repertoires, and protection are inter-related, provides a new way to measure the quality of T cell immunity, which if applied to vaccine evaluation, could enhance our understanding of how to elicit protective T cell immunity.This work was supported by the Portuguese Foundation for Science and Technology individual fellowship (CNA) www.fct.pt, a National Institutes of Health Grant R01 AI106725 (SMB) www.nih.gov, and a Center for AIDS Research Grant P30 AI 060354 (SMB) www.nih.gov. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript

Recent Change—North Sea

This chapter discusses past and ongoing change in the following physical variables within the North Sea: temperature, salinity and stratification; currents and circulation; mean sea level; and extreme sea levels. Also considered are carbon dioxide; pH and nutrients; oxygen; suspended particulate matter and turbidity; coastal erosion, sedimentation and morphology; and sea ice. The distinctive character of the Wadden Sea is addressed, with a particular focus on nutrients and sediments. This chapter covers the past 200 years and focuses on the historical development of evidence (measurements, process understanding and models), the form, duration and accuracy of the evidence available, and what the evidence shows in terms of the state and trends in the respective variables. Much work has focused on detecting long-term change in the North Sea region, either from measurements or with models. Attempts to attribute such changes to, for example, anthropogenic forcing are still missing for the North Sea. Studies are urgently needed to assess consistency between observed changes and current expectations, in order to increase the level of confidence in projections of expected future conditions

Towards improving the safety and diagnostic yield of stereotactic biopsy in a single centre

Background: Previously, we reported on our single centre results regarding the diagnostic yield of stereotactic needle biopsies of brain lesions. The yield then (1996-2006) was 89.4%. In the present study, we review and evaluate our experience with intraoperative frozen-section histopathologic diagnosis on-demand in order to improve the diagnostic yield. Methods: