What can mathematical models bring to the control of equine influenza?

Mathematical modelling of infectious disease is increasingly regarded as an important tool in the development of disease prevention and control measures. This article brings together key findings from various modelling studies conducted over the past 10 years that are of relevance to those on the front line of the battle against equine influenza

PRESERVATIVE TREATMENT OF TASMANIAN PLANTATION EUCALYPTUS NITENS USING SUPERCRITICAL FLUIDS

Short rotation plantation forests in Tasmania, Australia, are dominated by Eucalyptus nitens (common name: shining gum). These forests were primarily planted to provide material for pulp and paper production, but the timber is increasingly sought after for higher value and more enduring applications. Plantation E. nitens has a high proportion of low durability heartwood that resists penetration by conventional fluid preservatives. This limits its use to indoor applications. One approach to overcoming the refractory nature of E. nitens is to modify the treatment fluid. We investigated the use of supercritical carbon dioxide to deliver biocides deep into the wood. Timbers varying in thickness from 19 to 35 mm and 900 mm long were treated with a multicomponent biocide under supercritical conditions in a commercial facility in Denmark. The resulting timber was cut into zones inward from the surface. Wood from these zones was ground and extracted for HPLC analysis for tebuconazole and propiconazole. Preservative was detected in the inner portion of every sample examined, indicating that the process resulted in treatment throughout the boards, with concentrations meeting and on average exceeding the targeted amounts

The role of IL-6 in skin fibrosis and cutaneous wound healing

The timely resolution of wound healing is critical for restoring the skin as a protective barrier. The switch from a proinflammatory to a reparative microenvironment must be tightly regulated. Interleukin (IL)-6 is a key modulator of the inflammatory and reparative process: it is involved in the differentiation, activation, and proliferation of leukocytes, endothelial cells, keratinocytes, and fibroblasts. This review examines the role of IL-6 in the healing of cutaneous wounds, and how dysregulation of IL-6 signaling can lead to either fibrosis or a failure to heal. The role of an IL-6/TGF-β feedback loop is discussed in the context of fibrogenesis, while IL-6 expression and responses in advanced age, diabetes, and obesity is outlined regarding the development of chronic wounds. Current research on therapies that modulate IL-6 is explored. Here, we consider IL-6′s diverse impact on cutaneous wound healing

DO Leonis - a new eclipsing cataclysmic variable

Photometric and spectroscopic observations of DO Leo have been obtained using the McDonald Observatory high-speed CCD photometer and a conventional two-channel photoelectric photometer. The data reveal eclipses that are approximately 1.5 m deep. A total of nine eclipses were observed in February and March 1988 and in April 1989. These data were used to establish an orbital period of 0.2345147(2) d. A low-resolution optical spectrum reveals significant He II 4686 emission in addition to the characteristic Balmer and He I emission lines

What can mathematical models bring to the control of equine influenza?

Mathematical modelling of infectious disease is increasingly regarded as an important tool in the development of disease prevention and control measures. This article brings together key findings from various modelling studies conducted over the past 10 years that are of relevance to those on the front line of the battle against equine influenza

Magnetic core studies at LBNL and LLNL

The objective of this work is to minimize the cost of the materials and maximize the performance of magnetic cores, a major cost component of a Heavy-Ion-Fusion, HIF, induction accelerator driver. This includes selection of the alloy for cost and performance, and maximizing the performance of each alloy evaluated. The two major performance parameters are the magnetic flux swing and the energy loss. The volt seconds of the cores, obtained from the flux swing with Faraday's Law, determines the beam energy and duration. Core losses from forming domains and moving their boundaries are a major factor in determining the efficiency of an induction accelerator

Sensitivity of deexcitation energies of superdeformed secondary minima to the density dependence of symmetry energy with the relativistic mean-field theory

The relationship between deexcitation energies of superdeformed secondary minima relative to ground states and the density dependence of the symmetry energy is investigated for heavy nuclei using the relativistic mean field (RMF) model. It is shown that the deexcitation energies of superdeformed secondary minima are sensitive to differences in the symmetry energy that are mimicked by the isoscalar-isovector coupling included in the model. With deliberate investigations on a few Hg isotopes that have data of deexcitation energies, we find that the description for the deexcitation energies can be improved due to the softening of the symmetry energy. Further, we have investigated deexcitation energies of odd-odd heavy nuclei that are nearly independent of pairing correlations, and have discussed the possible extraction of the constraint on the density dependence of the symmetry energy with the measurement of deexcitation energies of these nuclei.Comment: 14 pages, 3 figure

Dark Matter signals from Draco and Willman 1: Prospects for MAGIC II and CTA

The next generation of ground-based Imaging Air Cherenkov Telescopes (IACTs) will play an important role in indirect dark matter searches. In this article, we consider two particularly promising candidate sources for dark matter annihilation signals, the nearby dwarf galaxies Draco and Willman 1, and study the prospects of detecting such a signal for the soon-operating MAGIC II telescope system as well as for the planned installation of CTA, taking special care of describing the experimental features that affect the detectional prospects. For the first time in such a study, we fully take into account the effect of internal bremsstrahlung, which has recently been shown to considerably enhance, in some cases, the gamma-ray flux at the high energies where Atmospheric Cherenkov Telescopes operate, thus leading to significantly harder annihilation spectra than traditionally considered. While the detection of the spectral features introduced by internal bremsstrahlung would constitute a smoking gun signature for dark matter annihilation, we find that for most models the overall flux still remains at a level that will be challenging to detect unless one adopts rather (though by no means overly) optimistic astrophysical assumptions about the distribution of dark matter in the dwarfs.Comment: 10 pages, 4 figures, minor changes, matches the published version (JCAP

Activity and Rotation of Nearby Field M Dwarfs in the TESS Southern Continuous Viewing Zone

The evolution of magnetism in late-type dwarfs remains murky, as we can only weakly predict levels of activity for M dwarfs of a given mass and age. We report results from our spectroscopic survey of M dwarfs in the Southern Continuous Viewing Zone (CVZ) of the Transiting Exoplanet Survey Satellite (TESS). As the TESS CVZs overlap with those of the James Webb Space Telescope, our targets constitute a legacy sample for studies of nearby M dwarfs. For 122 stars, we obtained at least one R ≈ 2000 optical spectrum with which we measure chromospheric Hα emission, a proxy for magnetic field strength. The fraction of active stars is consistent with what is expected for field M dwarfs; as in previous studies, we find that late-type M dwarfs remain active for longer than their early-type counterparts. While the TESS light curves for ≈20% of our targets show modulations consistent with rotation, TESS systematics are not well enough understood for confident measurements of rotation periods (P rot) longer than half the length of an observing sector. We report periods for 12 stars for which we measure P rot ≲ 15 days or find confirmation for the TESS-derived P rot in the literature. Our sample of 21 P rot, which includes periods from the literature, is consistent with our targets being spun-down field stars. Finally, we examine the Hα-to-bolometric luminosity distribution for our sample. Two stars are rotating fast enough to be magnetically saturated, but are not, hinting at the possibility that fast rotators may appear inactive in Hα