On polynomially integrable domains in Euclidean spaces

Let $D$ be a bounded domain in $\mathbb R^n,$ with smooth boundary. Denote $V_D(\omega,t), \ \omega \in S^{n-1}, t \in \mathbb R,$ the Radon transform of the characteristic function $\chi_{D}$ of the domain $D,$ i.e., the $(n-1)-$ dimensional volume of the intersection $D$ with the hyperplane $\{x \in \mathbb R^n: =t \}.$ If the domain $D$ is an ellipsoid, then the function $V_D$ is algebraic and if, in addition, the dimension $n$ is odd, then $V(\omega,t)$ is a polynomial with respect to $t.$ Whether odd-dimensional ellipsoids are the only bounded smooth domains with such a property? The article is devoted to partial verification and discussion of this question

Climate-Smart Cocoa in Ghana: How Ecological Modernisation Discourse Risks Side-Lining Cocoa Smallholders

Climate-smart agriculture (CSA) aims to transform and reorient farming systems to decrease greenhouse gas emissions, boost adaptive capacity, and improve productivity while supporting incomes and, ostensibly, food security. In Ghana—the world's second biggest cocoa producer—the cocoa sector is challenged by increasing global cocoa demand, climate change impacts, as well as mounting consumer pressure over cocoa's deforestation. Climate-smart cocoa (CSC) has emerged to address these challenges as well as to improve smallholder incomes. As with CSA more widely, there are concerns that CSC discourses will override the interests of cocoa smallholders, and lead to inequitable outcomes. To better understand if and how the implementation of CSC in Ghana can meet its lofty ambitions, we examine (1) the dominant CSC discourses as perceived by stakeholders, and their reflection in policy and practice, and (2) subsequent implications for cocoa smallholders through an equity lens. Through semi-structured interviews and focus group discussions with key stakeholders in Ghana's cocoa sector, we find overwhelming consensus for an ecological modernisation discourse with the promise of a “triple win” narrative that simultaneously stops deforestation, supports climate mitigation and adaptation, and increases smallholder livelihoods. Moreover, we find that implementing CSC on the ground has generally converged around “sustainable intensification” and private-sector-led partnerships that aspire to generate a “win-win” for environment and productivity objectives, but potentially at the expense of delivering equitable outcomes that serve smallholders' interests. We find that the success of CSC and the overly-simplistic sustainable intensification narrative is constrained by the lack of clear tree tenure rights, complexities around optimal shade trees levels, potential rebound effects regarding deforestation, and the risks of agrochemical-dependence. More positively, local governance mechanisms such as Ghana's Community Resource Management Area Mechanisms (CREMAs) may give cocoa smallholders a stronger voice to shape policy. However, we caution that the discursive power of dominant private sector actors may risk side-lining equity which could prove detrimental to the long-term wellbeing of Ghana's ~800,000 cocoa smallholders

Revisiting the relationships between human well-being and ecosystems in dynamic social-ecological systems: Implications for stewardship and development

This is the final version. Available from Cambridge University Press via the DOI in this record.Non-technical summary We argue that the ways in which we as humans derive well-being from nature - for example by harvesting firewood, selling fish or enjoying natural beauty - feed back into how we behave towards the environment. This feedback is mediated by institutions (rules, regulations) and by individual capacities to act. Understanding these relationships can guide better interventions for sustainably improving well-being and alleviating poverty. However, more attention needs to be paid to how experience-related benefits from nature influence attitudes and actions towards the environment, and how these relationships can be reflected in more environmentally sustainable development projects. Technical summary In the broad literatures that address the linked challenge of maintaining ecosystem integrity while addressing poverty and inequality, there is still a need to investigate how linkages and feedbacks between ecosystem services and well-being can be taken into account to ensure environmental sustainability and improved livelihoods. We present a conceptual model towards a dynamic and reciprocal understanding of the feedbacks between human well-being and ecosystems. The conceptual model highlights three mechanisms through which people derive benefits from ecosystems (use, money and experience), and illustrates how these benefits can affect values, attitudes and actions towards ecosystems. Institutions and agency determine access to and distribution of benefits and costs, and also present barriers or enabling factors for individual or collective action. The conceptual model synthesises insights from existing but mostly separate bodies of literature on well-being and the benefits humans derive from ecosystems, and reveals gaps and areas for future research. Two case studies illustrate how recognizing the full feedback loop between how ecosystems support human well-being and how people behave towards those ecosystems, as well as intervention points within the loop, can guide better action for sustainable poverty alleviation and stewardship of the biosphere.Swedish Research CouncilSwedish Research Counci

Search for electromagnetic properties of the neutrinos at the LHC

Exclusive production of neutrinos via photon-photon fusion provides an excellent opportunity to probe electromagnetic properties of the neutrinos at the LHC. We explore the potential of processes pp-> p gamma gamma p -> p nu anti-nu p and pp -> p gamma gamma p -> p nu anti-nu Z p to probe neutrino-photon and neutrino-two photon couplings. We show that these reactions provide more than seven orders of magnitude improvement in neutrino-two photon couplings compared to LEP limits.Comment: 11 pages, 4 tables, New backgrounds have been adde

HPV infection and immunochemical detection of cell-cycle markers in verrucous carcinoma of the penis

Penile verrucous carcinoma is a rare disease and little is known of its aetiology or pathogenesis. In this study we examined cell-cycle proteins expression and correlation with human papillomavirus infection in a series of 15 pure penile verrucous carcinomas from a single centre. Of 148 penile tumours, 15 (10%) were diagnosed as pure verrucous carcinomas. The expression of the cell-cycle-associated proteins p53, p21, RB, p16INK4A and Ki67 were examined by immunohistochemistry. Human papillomavirus infection was determined by polymerase chain reaction to identify a wide range of virus types. The expression of p16INK4A and Ki67 was significantly lower in verrucous carcinoma than in usual type squamous cell carcinoma, whereas the expression of p53, p21 and RB was not significantly different. p53 showed basal expression in contrast to usual type squamous cell carcinoma. Human papillomavirus infection was present in only 3 out of 13 verrucous carcinomas. Unique low-risk, high-risk and mixed viral infections were observed in each of the three cases. In conclusion, lower levels of p16INK4A and Ki67 expressions differentiate penile verrucous carcinoma from usual type squamous cell carcinoma. The low Ki67 index reflects the slow-growing nature of verrucous tumours. The low level of p16INK4A expression and human papillomavirus detection suggests that penile verrucous carcinoma pathogenesis is unrelated to human papillomavirus infection and the oncogenes and tumour suppressor genes classically altered by virus infection.Peer reviewedFinal Accepted Versio

Marital Status and Mortality among Middle Age and Elderly Men and Women in Urban Shanghai

Previous studies have suggested that marital status is associated with mortality, but few studies have been conducted in China where increasing aging population and divorce rates may have major impact on health and total mortality.We examined the association of marital status with mortality using data from the Shanghai Women's Health Study (1996–2009) and Shanghai Men's Health Study (2002–2009), two population-based cohort studies of 74,942 women aged 40–70 years and 61,500 men aged 40–74 years at the study enrollment. Deaths were identified by biennial home visits and record linkage with the vital statistics registry. Marital status was categorized as married, never married, divorced, widowed, and all unmarried categories combined. Cox regression models were used to derive hazard ratios (HR) and 95% confidence interval (CI).Unmarried and widowed women had an increased all-cause HR = 1.11, 95% CI: 1.03, 1.21 and HR = 1.10, 95% CI: 1.02, 1.20 respectively) and cancer (HR = 1.17, 95% CI: 1.04, 1.32 and HR = 1.18, 95% CI: 1.04, 1.34 respectively) mortality. Never married women had excess all-cause mortality (HR = 1.46, 95% CI: 1.03, 2.09). Divorce was associated with elevated cardiovascular disease (CVD) mortality in women (HR = 1.47, 95% CI: 1.01, 2.13) and elevated all-cause mortality (HR = 2.45, 95% CI: 1.55, 3.86) in men. Amongst men, not being married was associated with excess all-cause (HR = 1.45, 95% CI: 1.12, 1.88) and CVD (HR = 1.65, 95% CI: 1.07, 2.54) mortality.Marriage is associated with decreased all cause mortality and CVD mortality, in particular, among both Chinese men and women

Interleukin-1 polymorphisms associated with increased risk of gastric cancer

Helicobacter pylori infection is associated with a variety of clinical outcomes including gastric cancer and duodenal ulcer disease. The reasons for this variation are not clear, but the gastric physiological response is influenced by the severity and anatomical distribution of gastritis induced by H. pylori. Thus, individuals with gastritis predominantly localized to the antrum retain normal (or even high) acid secretion, whereas individuals with extensive corpus gastritis develop hypochlorhydria and gastric atrophy, which are presumptive precursors of gastric cancer. Here we report that interleukin-1 gene cluster polymorphisms suspected of enhancing production of interleukin-1-beta are associated with an increased risk of both hypochlorhydria induced by H. pylori and gastric cancer. Two of these polymorphism are in near-complete linkage disequilibrium and one is a TATA-box polymorphism that markedly affects DNA-protein interactions in vitro. The association with disease may be explained by the biological properties of interleukin-1-beta, which is an important pro-inflammatory cytokine and a powerful inhibitor of gastric acid secretion. Host genetic factors that affect interleukin-1-beta may determine why some individuals infected with H. pylori develop gastric cancer while others do no