741 research outputs found
What really matters? The elusive quality of the material in feminist thought
The concept of the 'material' was the focus of much feminist work in the 1970s. It has always been a deeply contested one, even for feminists working within a broadly materialist paradigm of the social. Materialist feminists stretched the concept of the material beyond the narrowly economic in their attempts to develop a social ontology of gender and sexuality. Nonetheless, the quality of the social asserted by an expanded sense of the material - its 'materiality' - remains ambiguous. New terminologies of materiality and materialization have been developed within post-structuralist feminist thought and the literature on embodiment. The quality of 'materiality' is no longer asserted - as in materialist feminisms - but is problematized through an implicit deferral of ontology in these more contemporary usages, forcing us to interrogate the limits of both materialist and post-structuralist forms of constructionism. What really matters is how these newer terminologies of 'materiality' and 'materialization' induce us to develop a fuller social ontology of gender and sexuality; one that weaves together social, cultural, experiential and embodied practices
Predicting the timing and potential of the spring emergence of overwintered populations of Heliothis spp
The current state of knowledge dealing with the prediction of the overwintering population and spring emergence of Heliothis spp., a serious pest of numerous crops is surveyed. Current literature is reviewed in detail. Temperature and day length are the primary factors which program H. spp. larva for possible diapause. Although studies on the interaction of temperature and day length are reported, the complete diapause induction process is not identified sufficiently to allow accurate prediction of diapause timing. Mortality during diapause is reported as highly variable. The factors causing mortality are identified, but only a few are quantified. The spring emergence of overwintering H. spp. adults and mathematical models which predict the timing of emergence are reviewed. Timing predictions compare favorably to observed field data; however, prediction of actual numbers of emerging moths is not possible. The potential for use of spring emergence predictions in pest management applications, as an early warning of potential crop damage, are excellent. Research requirements to develop such an early warning system are discussed
Conformation of Circular DNA in 2 Dimensions
The conformation of circular DNA molecules of various lengths adsorbed in a
2D conformation on a mica surface is studied. The results confirm the
conjecture that the critical exponent is topologically invariant and
equal to the SAW value (in the present case ), and that the topology
and dimensionality of the system strongly influences the cross-over between the
rigid regime and the self-avoiding regime at a scale .
Additionally, the bond correlation function scales with the molecular length
as predicted. For molecular lengths , circular DNA behaves
like a stiff molecule with approximately elliptic shape.Comment: 4 pages, 5 figure
Cooperative kinking at distant sites in mechanically stressed DNA
In cells, DNA is routinely subjected to significant levels of bending and twisting. In some cases, such as under physiological levels of supercoiling, DNA can be so highly strained, that it transitions into non-canonical structural conformations that are capable of relieving mechanical stress within the template. DNA minicircles offer a robust model system to study stress-induced DNA structures. Using DNA minicircles on the order of 100âbp in size, we have been able to control the bending and torsional stresses within a looped DNA construct. Through a combination of cryo-EM image reconstructions, Bal31 sensitivity assays and Brownian dynamics simulations, we have been able to analyze the effects of biologically relevant underwinding-induced kinks in DNA on the overall shape of DNA minicircles. Our results indicate that strongly underwound DNA minicircles, which mimic the physical behavior of small regulatory DNA loops, minimize their free energy by undergoing sequential, cooperative kinking at two sites that are located about 180° apart along the periphery of the minicircle. This novel form of structural cooperativity in DNA demonstrates that bending strain can localize hyperflexible kinks within the DNA template, which in turn reduces the energetic cost to tightly loop DN
The social geography of childcare: 'making up' the middle class child
Childcare is a condensate of disparate social forces and social processes. It is gendered and classed. It is subject to an excess of policy and political discourse. It is increasingly a focus for commercial exploitation. This is a paper reporting on work in progress in an ESRC funded research project (R000239232) on the choice and provision of pre-school childcare by middle class (service class) families in two contrasting London locations. Drawing on recent work in class analysis the paper examines the relationships between childcare choice, middle class fractions and locality. It suggests that on the evidence of the findings to date, there is some evidence of systematic differences between fractions in terms of values, perspectives and preferences for childcare, but a more powerful case for intra-class similarities, particularly when it comes to putting preferences into practice in the 'making up of a middle class child' through care and education
Plastic zone evolution during fatigue crack growth: Digital image correlation coupled with finite elements method
International audienceNonlinearities effects at the crack tip, due to the elastic-plastic material behavior , impact the crack growth rate and path. This paper is devoted to the study of the plastic zone evolution in the crack tip region. The methodology relies on coupling an elastic-plastic Finite Elements Method (FEM) model and experimental displacements measured by Digital Image Correlation (DIC). These latter are introduced as Dirichlet boundary conditions in the finite elements analysis. The considered FEM domain is constant, i.e. the same mesh with a centered crack is moved to each new crack tip position deduced from DIC. The new boundary conditions are updated and the residual stresses and plastic strains of the former computation are interpolated and actualized on the mesh shifted to the new crack tip position in order to incorporate them in the numerical model. The coupling method allowed applying experimental boundary conditions in order to be as close as possible to real experimental conditions and to observe the plasticity evolution from small to large scale yielding conditions. A fatigue test was conducted to validate the proposed approach. The identification residues are proved to be lower than those obtained with an experimental displacements projection onto Williams' series basis, which is a method commonly used with DIC. The coupling results present an attractive similarity with Irwin's model regardless of the crack length. Thus, the definition of the mask needed for the displacements fields projection on Williams' model can be deduced with a reliable estimate of Irwin's plastic radius
Fractal Dimension and Localization of DNA Knots
The scaling properties of DNA knots of different complexities were studied by
atomic force microscope. Following two different protocols DNA knots are
adsorbed onto a mica surface in regimes of (i) strong binding, that induces a
kinetic trapping of the three-dimensional (3D) configuration, and of (ii) weak
binding, that permits (partial) relaxation on the surface. In (i) the gyration
radius of the adsorbed DNA knot scales with the 3D Flory exponent within error. In (ii), we find , a value between the 3D
and 2D () exponents, indicating an incomplete 2D relaxation or a
different polymer universality class. Compelling evidence is also presented for
the localization of the knot crossings in 2D.Comment: 4 pages, 3 figure
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