D7-Brane Chaotic Inflation

We analyze string-theoretic large-field inflation in the regime of spontaneously-broken supergravity with conventional moduli stabilization by fluxes and non-perturbative effects. The main ingredient is a shift-symmetric Kahler potential, supplemented by flux-induced shift symmetry breaking in the superpotential. The central technical observation is that all these features are present for D7-brane position moduli in Type IIB orientifolds, allowing for a realization of the axion monodromy proposal in a controlled string theory compactification. On the one hand, in the large complex structure regime the D7-brane position moduli inherit a shift symmetry from their mirror-dual Type IIA Wilson lines. On the other hand, the Type IIB flux superpotential generically breaks this shift symmetry and allows, by appealing to the large flux discretuum, to tune the relevant coefficients to be small. The shift-symmetric direction in D7-brane moduli space can then play the role of the inflaton: While the D7-brane circles a certain trajectory on the Calabi-Yau many times, the corresponding F-term energy density grows only very slowly, thanks to the above-mentioned tuning of the flux. Thus, the large-field inflationary trajectory can be realized in a regime where Kahler, complex structure and other brane moduli are stabilized in a conventional manner, as we demonstrate using the example of the Large Volume Scenario.Comment: 8 pages, 2 figures; v2: references adde

Justice Without Partiality : Women and the Law in Colonial Maryland, 1648-1715

What was the legal status of women in early colonial Maryland? This is the central question answered by this dissertation. Women, as exemplified through a series of case studies, understood the law and interacted with the nascent Maryland legal system. Each of the cases in the following chapters is slightly different. Each case examined in this dissertation illustrates how much independent legal agency women in the colony demonstrated. Throughout the seventeenth century, Maryland women appeared before the colony\u27s Provincial and county courts as witnesses, plaintiffs, defendants, and attorneys in criminal and civil trials. Women further entered their personal cattle marks, claimed land, and sued other colonists. This study asserts that they improved their social standing through these interactions with the courts. By exerting this much legal knowledge, they created an important place for themselves in Maryland society. Historians have begun to question the interpretation that Southern women were restricted to the home as housewives and mothers. The research in this dissertation illustrates that the female role in Maryland\u27s legal system refutes this assumption specifically about Maryland women. Studies of Maryland, whether of society, women, or the law, are numerically fewer than studies of other colonies. This includes the other southern colonies. Nevertheless, in the past twenty years, there has been a historiographical shift toward rehabilitating the role women had in society. This dissertation contributes to that trend by illustrating women\u27s agency outside of the household. Maryland was unique. As the first British colony to allow all Christians freedom of conscience, Maryland had a society that allowed rights for a variety of people. Extending from this point, the Maryland legal structure in the early colonial period allowed women many rights. As the system developed, women learned to understand how to use and abuse the legal system. This is evident in the four categories of crimes in this dissertation. Witchcraft, violent crimes, sexual offenses, and property offenses all involved females in different capacities. It was this experience with these varied cases that helped women from 1648 through 1715 carve out a place for themselves in society

Peer Prediction without a Common Prior

Reputation mechanisms at online opinion forums, such as Amazon Reviews, elicit ratings from users about their experience with different products. Crowdsourcing applications, such as image tagging on Amazon Mechanical Turk, elicit votes from users as to whether or not a job was duly completed. An important property in both settings is that the feedback received from users (agents) is truthful. The peer prediction method introduced by Miller et al. [2005] is a prominent theoretical mechanism for the truthful elicitation of reports. However, a significant obstacle to its application is that it critically depends on the assumption of a common prior amongst both the agents and the mechanism. In this paper, we develop a peer prediction mechanism for settings where the agents hold subjective and private beliefs about the state of the world and the likelihood of a positive signal given a particular state. Our shadow peer prediction mechanism exploits temporal structure in order to elicit two reports, a belief report and then a signal report, and it provides strict incentives for truthful reporting as long as the effect an agent's signal has on her posterior belief is bounded away from zero. Alternatively, this technical requirement on beliefs can be dispensed with by a modification in which the second report is a belief report rather than a signal report.Engineering and Applied Science

A Robust Bayesian Truth Serum for Small Populations

Peer prediction mechanisms allow the truthful elicitation of private signals (e.g., experiences, or opinions) in regard to a true world state when this ground truth is unobservable. The original peer prediction method is incentive compatible for any number of agents n >= 2, but relies on a common prior, shared by all agents and the mechanism. The Bayesian Truth Serum (BTS) relaxes this assumption. While BTS still assumes that agents share a common prior, this prior need not be known to the mechanism. However, BTS is only incentive compatible for a large enough number of agents, and the particular number of agents required is uncertain because it depends on this private prior. In this paper, we present a robust BTS for the elicitation of binary information which is incentive compatible for every n >= 3, taking advantage of a particularity of the quadratic scoring rule. The robust BTS is the first peer prediction mechanism to provide strict incentive compatibility for every n >= 3 without relying on knowledge of the common prior. Moreover, and in contrast to the original BTS, our mechanism is numerically robust and ex post individually rational.Engineering and Applied Science

Soft X-ray Excess in the Coma Cluster from a Cosmic Axion Background

We show that the soft X-ray excess in the Coma cluster can be explained by a cosmic background of relativistic axions converting into photons in the cluster magnetic field. We provide a detailed self-contained review of the cluster soft X-ray excess, the proposed astrophysical explanations and the problems they face, and explain how a 0.1-1 keV axion background naturally arises at reheating in many string theory models of the early universe. We study the morphology of the soft excess by numerically propagating axions through stochastic, multi-scale magnetic field models that are consistent with observations of Faraday rotation measures from Coma. By comparing to ROSAT observations of the 0.2-0.4 keV soft excess, we find that the overall excess luminosity is easily reproduced for $g_{a\gamma\gamma} \sim 2 \times 10^{-13}$ GeV$^{-1}$. The resulting morphology is highly sensitive to the magnetic field power spectrum. For Gaussian magnetic field models, the observed soft excess morphology prefers magnetic field spectra with most power in coherence lengths on ${\cal O}(3 {\rm ~kpc})$ scales over those with most power on ${\cal O}(12 {\rm ~kpc})$ scales. Within this scenario, we bound the mean energy of the axion background to $50\, {\rm eV}\lesssim \langle E_a \rangle \lesssim 250\, {\rm eV}$, the axion mass to $m_a \lesssim 10^{-12}\,\hbox{eV}$, and derive a lower bound on the axion-photon coupling $g_{a\gamma\gamma} \gtrsim \sqrt{0.5/\Delta N_{\rm eff}}\, 1.4 \times 10^{-13}$ GeV$^{-1}$.Comment: 43 pages, 11 figure

Current challenges in de novo plant genome sequencing and assembly

ABSTRACT: Genome sequencing is now affordable, but assembling plant genomes de novo remains challenging. We assess the state of the art of assembly and review the best practices for the community

Dwelling on the Negative: Incentivizing Effort in Peer Prediction

Agents are asked to rank two objects in a setting where effort is costly and agents differ in quality (which is the probability that they can identify the correct, ground truth, ranking). We study simple output-agreement mechanisms that pay an agent in the case she agrees with the report of another, and potentially penalizes for disagreement through a negative payment. Assuming access to a quality oracle, able to determine whether an agent's quality is above a given threshold, we design a payment scheme that aligns incentives so that agents whose quality is above this threshold participate and invest effort. Precluding negative payments leads the expected cost of this quality-oracle mechanism to increase by a factor of 2 to 5 relative to allowing both positive and negative payments. Dropping the assumption about access to a quality oracle, we further show that negative payments can be used to make agents with quality lower than the quality threshold choose to not to participate, while those above continue to participate and invest effort. Through the appropriate choice of payments, any design threshold can be achieved. This self-selection mechanism has the same expected cost as the cost-minimal quality-oracle mechanism, and thus when using the self-selection mechanism, perfect screening comes for free.Engineering and Applied Science

Combined use of dermoscopy, reflectance confocal microscopy and ex-vivo gene expression profiling to detect a micro-melanoma less than 1 mm in diameter

.Micro-melanomas, or melanomas < 2 mm in diameter, are increasingly reported making screening methods like the ABCD(E) acronym outdated. Early detection of melanoma remains the utmost important prognostic factor, therefore understanding how to utilize different diagnostic tools is necessary to optimize detection of melanoma at its earliest, most treatable stage. Using a combination of imaging and molecular techniques, we detected and confirmed a micro-melanoma in situ measuring 0.65 mm in diamete

Ku-band high efficiency GaAs MMIC power amplifiers

The development of Ku-band high efficiency GaAs MMIC power amplifiers is examined. Three amplifier modules operating over the 13 to 15 GHz frequency range are to be developed. The first MMIC is a 1 W variable power amplifier (VPA) with 35 percent efficiency. On-chip digital gain control is to be provided. The second MMIC is a medium power amplifier (MPA) with an output power goal of 1 W and 40 percent power-added efficiency. The third MMIC is a high power amplifier (HPA) with 4 W output power goal and 40 percent power-added efficiency. An output power of 0.36 W/mm with 49 percent efficiency was obtained on an ion implanted single gate MESFET at 15 GHz. On a dual gate MESFET, an output power of 0.42 W/mm with 27 percent efficiency was obtained. A mask set was designed that includes single stage, two stage, and three stage single gate amplifiers. A single stage 600 micron amplifier produced 0.4 W/mm output power with 40 percent efficiency at 14 GHz. A four stage dual gate amplifier generated 500 mW of output power with 20 dB gain at 17 GHz. A four-bit digital-to-analog converter was designed and fabricated which has an output swing of -3 V to +/- 1 V