4,895 research outputs found
TRUSTWORTHINESS AS AN ECONOMIC ASSET
The evaluation of trust in economic decision making remains on the periphery of mainstream economic analysis and teaching. Yet business managers use trustworthiness in daily exchanges to create competitive advantages for their firms. An exploratory empirical test of Barney and HansenÂ’s three levels of trust (weak, semistrong, and strong) and Lewicki and BunkerÂ’s portfolio of governance mechanisms revealed that strong-form trust exists in day-to-day business relationships along with other governance mechanisms. Identity-based transactions were more prevalent than were weak trust market exchanges in important economic transactions.Institutional and Behavioral Economics, International Relations/Trade,
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Tofacitinib in the management of active psoriatic arthritis: patient selection and perspectives.
Tofacitinib is an oral Janus kinase inhibitor approved for the treatment of psoriatic arthritis (PsA). It provides an alternative option for patients who have had an inadequate response and tolerance to other disease modifying antirheumatic drugs (DMARDs). It has demonstrated comparable efficacy to biologics, is effective in the management of treatment resistant disease, and is reported to improve enthesitis, dactylitis, and radiographic progression. Tofacitinib is also associated with an increased risk of serious infections, malignancy, and laboratory abnormalities. There is currently a large armamentarium of therapies for psoriatic arthritis, and choosing among treatments can be challenging. Due to this wide selection, a thorough assessment of psoriatic disease phenotype, patient preference, disease presentation, and comorbidities is critical. This review addresses key considerations in patient selection for the treatment of PsA with tofacitinib
Chapter The representation of the sun in Paulo Mendes da Rocha and Decio Tozzi architectural drawings
The 43rd UID conference, held in Genova, takes up the theme of ‘Dialogues’ as practice and debate on many fundamental topics in our social life, especially in these complex and not yet resolved times. The city of Genova offers the opportunity to ponder on the value of comparison and on the possibilities for the community, naturally focused on the aspects that concern us, as professors, researchers, disseminators of knowledge, or on all the possibile meanings of the discipline of representation and its dialogue with ‘others’, which we have broadly catalogued in three macro areas: History, Semiotics, Science / Technology. Therefore, “dialogue” as a profitable exchange based on a common language, without which it is impossible to comprehend and understand one another; and the graphic sign that connotes the conference is the precise transcription of this concept: the title ‘translated’ into signs, derived from the visual alphabet designed for the visual identity of the UID since 2017. There are many topics which refer to three macro sessions: - Witnessing (signs and history) - Communicating (signs and semiotics) - Experimenting (signs and sciences) Thanks to the different points of view, an exceptional resource of our disciplinary area, we want to try to outline the prevailing theoretical-operational synergies, the collaborative lines of an instrumental nature, the recent updates of the repertoires of images that attest and nourish the relations among representation, history, semiotics, sciences
Changes to women’s childbirth plans during the COVID-19 pandemic and posttraumatic stress symptoms:a cross-national study
Improving bankruptcy prediction in micro-entities by using nonlinear effects and non-financial variables
The use of non-parametric methodologies, the introduction of non-financial variables,
and the development of models geared towards the homogeneous characteristics of
corporate sub-populations have recently experienced a surge of interest in the bankruptcy
literature. However, no research on default prediction has yet focused on micro-entities
(MEs), despite such firms’ importance in the global economy. This paper builds the first
bankruptcy model especially designed for MEs by using a wide set of accounts from 1999
to 2008 and applying artificial neural networks (ANNs). Our findings show that ANNs
outperform the traditional logistic regression (LR) models. In addition, we also report
that, thanks to the introduction of non-financial predictors related to age, the delay
in filing accounts, legal action by creditors to recover unpaid debts, and the ownership
features of the company, the improvement with respect to the use of solely financial
information is 3.6%, which is even higher than the improvement that involves the use
of the best ANN (2.6%)
Dinâmica do fluxo de conhecimento entre firmas localizadas em sistemas locais de produção: proximidade geográfica, relações verticais e aprendizagem por interação
XX Encontro Nacional de Economia Política: desenvolvimento Latino-Americano, Integração e Inserção Internacional - UNILA, Foz do Iguaçu, 26 a 29 de maio de 2015O objetivo central do artigo é compreender o padrão de geração de
inovações de fi rmas localizadas em Sistemas Locais de Produção a
partir da análise das relações que estabelecem com os demais atores
desses sistemas. Ao privilegiar-se aqui as relações verticais – entre as
fi rmas e seus clientes e fornecedores do local e extra-local - entende-
se que o presente estudo contribui para a literatura desse campo de
estudo. Foram objeto de estudo dois grupos de fi rmas de um mesmo
segmento produtivo – o de máquinas para calçados -, pertencentes
a dois Sistemas Locais de Produção (SLP) de calçados, o do Vale do
Rio dos Sinos no Brasil e o de Vigevano na Itália. Como referencial
teórico e analítico utilizou-se a literatura neo-schumpeteriana que
explicita que a inovação envolve mudanças contínuas e progressivas
por meio de diferentes processos de aprendizagem. Em termos
metodológicos, destaca-se que as fi rmas dos dois SLP investigados
foram alvo de entrevistas presenciais realizadas com base em um
questionário estruturado. Pode-se destacar que, comparativamente
às relações horizontais, verifi cou-se que as relações verticais entre
as fi rmas produtoras de maquinário para calçados e seus clientes e
fornecedores são mais frequentes em ambos os sistemas produtivos
analisados. Dentre os aprendizados externos às fi rmas, foi o learning-
by-interaction aquele mais ressaltado e que encontra-se, assim, como
um elemento explicativo da dinâmica de geração de inovações. A
proximidade geográfi ca em ambos os sistemas analisados importa
no estabelecimento das redes de conhecimento entre os atores-chave
no processo inovativo. Por fi m, os achados da pesquisa de campo
vão ao encontro das características do padrão setorial de segmentos
produtores de equipamentos e maquinário, identificados como
specialised suppliersBanco Nacional de Desenvolvimento Econômico e Social (BNDES); Usina Hidrelétrica de Itaipu (ITAIPU); Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) e Universidade Federal da Integração Latino-Americana (UNILA
Personalidad de las marcas de ropa en la comunidad LGBT: un estudio empírico para Bogotá
60 páginasTeniendo en cuenta el momento actual en el que se encuentra la sociedad, en donde hay nuevos segmentos de mercado que ie exigen a las marcas transformarse para cumplir sus necesidades, el mercado conformado por la comunidad LGTB representa una oportunidad de crecimiento para las empresas, pues son personas en su mayoría con alto poder adquisitivo, que el no tener conformada una familia con hijos les permite tener mayor libertad financiera, en la cual gran parte de su salario es destinado para la compra de ropa y entretenimiento. Este trabajo, denominado “PERSONALIDAD DE LAS MARCAS DE ROPA EN LA COMUNIDAD LGBT EN BOGOTÁ", explora todo el entorno de la comunidad LGBT, sus características demográficas, gustos, tendencias, marcas favoritas, y demás factores que inciden en su frecuencia de compra. Para analizar todos estos aspectos, partimos desde la definición del concepto de personalidad de marca realizada por la autora Jennifer Aaker, v de las dimensiones para medirla, las cuales nos permitieron establecer cuál es la personalidad que tiene una marca y a qué clase de arquetipo pertenece.Keep in mind the current situation of society, where there are new market segments that require brands to transform to meet their needs, the LGTB market represents a growth opportunity for companies, as they are mostly people with high purchasing power, with childless families which allows them to have a greater financial freedom, and much of their salary is used for the purchase of clothing and entertainment. This work, called "PERSONALITY OF CLOTHING BRANDS IN THE LGBT COMMUNITY IN BOGOTÁ", explores the whole setting of the LGBT community in this city, its demographic characteristics, tastes, trends, favorite brands, and other factors that influence their purchase frequency. To analyze all these aspects, we start from the definition of the concept of Brand Personality by the author Jennifer Aaker, and of the dimensions to measure it, which allowed us to establish to which personality and archetype a brand belongs to.Magíster en MercadeoMaestrí
Perspectives on Mechanisms Supporting Neuronal Polarity From Small Animals to Humans
Axon-dendrite formation is a crucial milestone in the life history of neurons. During this process, historically referred as “the establishment of polarity,” newborn neurons undergo biochemical, morphological and functional transformations to generate the axonal and dendritic domains, which are the basis of neuronal wiring and connectivity. Since the implementation of primary cultures of rat hippocampal neurons by Gary Banker and Max Cowan in 1977, the community of neurobiologists has made significant achievements in decoding signals that trigger axo-dendritic specification. External and internal cues able to switch on/off signaling pathways controlling gene expression, protein stability, the assembly of the polarity complex (i.e., PAR3-PAR6-aPKC), cytoskeleton remodeling and vesicle trafficking contribute to shape the morphology of neurons. Currently, the culture of hippocampal neurons coexists with alternative model systems to study neuronal polarization in several species, from single-cell to whole-organisms. For instance, in vivo approaches using C. elegans and D. melanogaster, as well as in situ imaging in rodents, have refined our knowledge by incorporating new variables in the polarity equation, such as the influence of the tissue, glia-neuron interactions and three-dimensional development. Nowadays, we have the unique opportunity of studying neurons differentiated from human induced pluripotent stem cells (hiPSCs), and test hypotheses previously originated in small animals and propose new ones perhaps specific for humans. Thus, this article will attempt to review critical mechanisms controlling polarization compiled over decades, highlighting points to be considered in new experimental systems, such as hiPSC neurons and human brain organoids.Fil: Wilson Rodriguez, Carlos. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Centro Cientifico Tecnologico Conicet - Cordoba. Instituto de Investigacion Medica Mercedes y Martin Ferreyra. Grupo Vinculado Centro de Investigacion En Medicina Traslacional Severo R. Amuchastegui - Cimetsa | Universidad Nacional de Cordoba. Instituto de Investigacion Medica Mercedes y Martin Ferreyra. Grupo Vinculado Centro de Investigacion En Medicina Traslacional Severo R. Amuchastegui - Cimetsa | Instituto de Investigacion Medica Mercedes y Martin Ferreyra. Instituto de Investigacion Medica Mercedes y Martin Ferreyra. Grupo Vinculado Centro de Investigacion En Medicina Traslacional Severo R. Amuchastegui - Cimetsa.; ArgentinaFil: Moyano, Ana Lis. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Centro Cientifico Tecnologico Conicet - Cordoba. Instituto de Investigacion Medica Mercedes y Martin Ferreyra. Grupo Vinculado Centro de Investigacion En Medicina Traslacional Severo R. Amuchastegui - Cimetsa | Universidad Nacional de Cordoba. Instituto de Investigacion Medica Mercedes y Martin Ferreyra. Grupo Vinculado Centro de Investigacion En Medicina Traslacional Severo R. Amuchastegui - Cimetsa | Instituto de Investigacion Medica Mercedes y Martin Ferreyra. Instituto de Investigacion Medica Mercedes y Martin Ferreyra. Grupo Vinculado Centro de Investigacion En Medicina Traslacional Severo R. Amuchastegui - Cimetsa.; ArgentinaFil: Caceres, Alfredo Oscar. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Centro Cientifico Tecnologico Conicet - Cordoba. Instituto de Investigacion Medica Mercedes y Martin Ferreyra. Grupo Vinculado Centro de Investigacion En Medicina Traslacional Severo R. Amuchastegui - Cimetsa | Universidad Nacional de Cordoba. Instituto de Investigacion Medica Mercedes y Martin Ferreyra. Grupo Vinculado Centro de Investigacion En Medicina Traslacional Severo R. Amuchastegui - Cimetsa | Instituto de Investigacion Medica Mercedes y Martin Ferreyra. Instituto de Investigacion Medica Mercedes y Martin Ferreyra. Grupo Vinculado Centro de Investigacion En Medicina Traslacional Severo R. Amuchastegui - Cimetsa.; Argentin
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A flexible organic reflectance oximeter array.
Transmission-mode pulse oximetry, the optical method for determining oxygen saturation in blood, is limited to only tissues that can be transilluminated, such as the earlobes and the fingers. The existing sensor configuration provides only single-point measurements, lacking 2D oxygenation mapping capability. Here, we demonstrate a flexible and printed sensor array composed of organic light-emitting diodes and organic photodiodes, which senses reflected light from tissue to determine the oxygen saturation. We use the reflectance oximeter array beyond the conventional sensing locations. The sensor is implemented to measure oxygen saturation on the forehead with 1.1% mean error and to create 2D oxygenation maps of adult forearms under pressure-cuff-induced ischemia. In addition, we present mathematical models to determine oxygenation in the presence and absence of a pulsatile arterial blood signal. The mechanical flexibility, 2D oxygenation mapping capability, and the ability to place the sensor in various locations make the reflectance oximeter array promising for medical sensing applications such as monitoring of real-time chronic medical conditions as well as postsurgery recovery management of tissues, organs, and wounds
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