Noise source identification on large generator units

Abstract unavailable please refer to PD

Attitudes towards parental presence at induction of anaesthesia

No Abstract

To Blink or Not to Blink: Fine Cognitive Tuning of the Defensive Peripersonal Space

The blink reflex elicited by the electrical stimulation of the median nerve at the wrist (hand blink reflex, HBR) is a subcortical, defensive response that is enhanced when the stimulated hand is inside the peripersonal space of the face. Such enhancement results from a tonic, topdown modulation of the excitability of the brainstem interneurons mediating the HBR. Here we aim to (1) characterize the somatotopical specificity of this top down modulation and (2) investigate the effect of cognitive expectations on such modulation. Experiment 1 showed that the somatotopical specificity of the HBR enhancement is not only heterosegmental, but also partially homosegmental, i.e. the enhancement is greater for the HBR elicited by stimulation of the hand located inside the peripersonal space of the face, as compared to the HBR elicited by the stimulation of the other hand, always kept far from the face. Experiment 2 showed that the top-down modulation of the HBR is triggered only when the participants expect to receive stimuli on the hand placed inside the peripersonal space of the face, and is thus strongly dependent on cognitive expectations. Taken together, these findings indicate a fine somatotopical and cognitive tuning of the excitability of brainstem circuits subserving the HBR, whose strength is adjusted depending on the context in a purposeful manner

Are we teaching our students what they need to know about ageing? Results from the National Survey of Undergraduate Teaching in Ageing and Geriatric Medicine

Introduction - Learning about ageing and the appropriate management of older patients is important for all doctors. This survey set out to evaluate what medical undergraduates in the UK are taught about ageing and geriatric medicine and how this teaching is delivered. Methods – An electronic questionnaire was developed and sent to the 28/31 UK medical schools which agreed to participate. Results – Full responses were received from 17 schools. 8/21 learning objectives were recorded as taught, and none were examined, across every school surveyed. Elder abuse and terminology and classification of health were taught in only 8/17 and 2/17 schools respectively. Pressure ulcers were taught about in 14/17 schools but taught formally in only 7 of these and examined in only 9. With regard to bio- and socio- gerontology, only 9/17 schools reported teaching in social ageing, 7/17 in cellular ageing and 9/17 in the physiology of ageing. Discussion – Even allowing for the suboptimal response rate, this study presents significant cause for concern with UK undergraduate education related to ageing. The failure to teach comprehensively on elder abuse and pressure sores, in particular, may be significantly to the detriment of older patients

Species reintroduction and community-level consequences in dynamically simulated ecosystems

Global biodiversity, and its associated ecosystem services, are threatened due to species extinctions. Reintroducing locally extinct species may be a partial solution to this problem. However, the success and possible consequences of any artificial reintroduction will depend on its ecological community, and the reaction of that community to the species' extinction and reintroduction. Mathematical models can offer useful insights by identifying the key features of communities and reintroduced species most likely to result in successful reintroductions. Here we simulated extinctions and reintroductions for a range of theoretical food webs generated using an established bioenergetics model. This allows the probability of successful reintroductions to be quantified as a function of two important ecological factors: the connectance of the food web, and of the time between extinctions and reintroductions. Reintroduction success is measured across an ensemble of 1796 simulated communities, with connnectances of 0.05, 0.15 and 0.3, using three criteria: presence of the reintroduced species in the final community, unchanged species richness in the final community compared to the pre-extinction persistent community and the complete restoration of the community (including both species richness and equilibrium biomass distributions). Although only 12 reintroduced species fail to re-establish according to minimal criteria, the process of extinction and reintroduction frequently has a large effect on the community composition. Increasing time to reintroduction increases both the probability of species loss, and equilibrium biomass change in the community. Proportionally, these community-level impacts occur more frequently when the reintroduced species is a primary producer or top predator. These results indicate that ignoring broader measures of reintroduction success could seriously underestimate the impact of reintroductions on the ecological community. These quantitative results can be compared to empirical literature and may help reveal which factors are most important to the success of reintroductions

Molten Salt Fuel Cycle Requirements for ADTT Applications

The operation of an ADT system with the associated nuclear reactions has a profound effect upon the chemistry of the fuel - especially with regards to container compatibility and the chemical separations that may be required. The container can be protected by maintaining the redox chemistry within a relatively narrow, non-corrosive window. Neutron economy as well as other factors require a sophisticated regime of fission product separations. Neither of these control requirements has been demonstrated on the scale or degree of sophistication necessary to support an ADT device. We review the present situation with respect to fluoride salts, and focus on the critical issues in these areas which must be addressed. One requirement for advancement in this area - a supply of suitable materials - will soon be fulfilled by the remediation of ORNL�s Molten Salt Reactor Experiment, and the removal of a total of 11,000 kg of enriched (Li-7 > 99.9%) coolant, flush, and fuel salts

Lowest observed surface and weld losses in fused silica fibres for gravitational wave detectors

High purity fused silica has become the cornerstone choice for use in the final monolithic stage of the mirror suspensions in the gravitational wave observatories Advanced LIGO (aLIGO) and Advanced Virgo (AdV). The ultra-low thermal noise contributed by these suspensions is one of the key improvements that permitted the Nobel prize winning first direct measurement of gravitational waves in 2015. This paper outlines the first in situ study undertaken to analyse the thermal noise of the final monolithic stage of the aLIGO Hanford detector mirror suspensions. We analysed short operational periods of this detector, when high excitation of the transverse 'violin' modes of the silica suspension fibres occurred. This allowed detailed measurements of the Q-factor of violin modes up to order 8 of individual fibres on separate masses. We demonstrate the highest silica fibre violin mode Q-factors yet measured of up to 2 × 109. From finite element modelling, the dominant surface and weld losses have been calculated to be a factor of 3 to 4 better than previously accepted, and as a result, we demonstrate that the level of noise in the aLIGO final stage silica suspensions is around 30%–40% better than previously estimated between frequencies of 10–500 Hz. This leads to an increase in the estimated event rate by a factor of 2 for aLIGO, if suspension thermal noise became the main limitation to the sensitivity of the detector

Review of ORNL`s MSR technology and status

The current status of molten salt reactor development is discussed with reference to the experience from the Oak Ridge Molten Salt Reactor Experiment. Assessment of the future for this reactor system is reviewed with consideration of both advantages and disadvantages. Application of this concept to ADTT (accelerator driven transmutation technology) needs appears to be feasible by drawing on the MSRE experience. Key chemical considerations remain as: solubility, redox behavior, and chemical activity and their importance to ADTT planning is briefly explained. Priorities in the future development of molten salts for these applications are listed, with the foremost being the acceptance of the 2LiF-BeF{sub 2} solvent system. 8 refs, 2 figs

Compensation between meridional flow components of the Atlantic MOC at 26°N

From ten years of observations of the Atlantic meridional overturning circulation (MOC) at 26° N (2004–2014), we revisit the question of flow compensation between components of the circulation. Contrasting with early results from the observations, transport variations of the Florida Current (FC) and upper mid-ocean (UMO) transports (top 1000 m east of the Bahamas) are now found to compensate on sub-annual timescales. The observed compensation between the FC and UMO transports is associated with horizontal circulation and means that this part of the correlated variability does not project onto the MOC. A deep baroclinic response to wind-forcing (Ekman transport) is also found in the lower North Atlantic Deep Water (LNADW; 3000–5000 m) transport. In contrast, co-variability between Ekman and the LNADW transports does contribute to overturning. On longer timescales, the southward UMO transport has continued to strengthen, resulting in a continued decline of the MOC. Most of this interannual variability of the MOC can be traced to changes in isopycnal displacements on the western boundary, within the top 1000 m and below 2000 m. Substantial trends are observed in isopycnal displacements in the deep ocean, underscoring the importance of deep boundary measurements to capture the variability of the Atlantic MOC