Non-Market Valuation of Open Space and Other Amenities Associated with Retention of Lands in Agricultural Use

The most productive farmland in southcentral Alaska is currently under intense development pressure due to rapid population increases and consequential increases in demand for suburban housing. This study utilizes a contingent valuation iterative bidding game to estimate the willingness of Matanuska-Susitna Borough residents to pay to preserve open space and other historical/environmental amenities associated with farming activities. Determinants of consumer behavior are addressed as well as total benefits and costs of various posited development scenarios. This information may be useful to policymakers assessing actions designed to purchase development rights from Matanuska-Susitna farmers

Capital and Punishment: Resource Scarcity Increases Endorsement of the Death Penalty

Faced with punishing severe offenders, why do some prefer imprisonment whereas others impose death? Previous research exploring death penalty attitudes has primarily focused on individual and cultural factors. Adopting a functional perspective, we propose that environmental features may also shape our punishment strategies. Individuals are attuned to the availability of resources within their environments. Due to heightened concerns with the costliness of repeated offending, we hypothesize that individuals tend toward elimination-focused punishments during times of perceived scarcity. Using global and United States data sets (studies 1 and 2), we find that indicators of resource scarcity predict the presence of capital punishment. In two experiments (studies 3 and 4), we find that activating concerns about scarcity causes people to increase their endorsement for capital punishment, and this effect is statistically mediated by a reduced willingness to risk repeated offenses. Perceived resource scarcity shapes our punishment preferences, with important policy implications

Deracialization and Democracy

The United States suffers the conthiued costs of mahitainhig a racial hierarchy. Enhanced diversity and growhig realization of the economic costs of that hierarchy could lead to democratic pressure for reform. Yet, in the U.S., elites on the radical right seek to entrench themselves in power through the constriction of voting power and the strategic use of the racial hierarchy as a political tool. This Article traces the anti-democratic efforts of the radical right to limit the political power of the nation\u27s enhanced diversity, and to utilize archaic governance measures to entrench themselves politically, regardless of the costs of allowing the racial hierarchy to continue to fester. Antidemocratic efforts to limit voting power to assure non-democratic governance and outcomes recently scored significant success as recounted in this Article. The anti-democratic contrivances to limit the power of enhanced diversity requires comparable countermeasures to vindicate the core value of expanded democracy that find its roots in our history and in the Constitution\u27s trajectory towards ever greater democratic governance. This Article surveys countermeasures that could lead to the preservation and even expansion of democratic governance. It concludes that only through a renewed pursuit of expansive voting rights can we restore our democracy and move the nation away from its racist past

Targeting lymphatic vessel functions through tyrosine kinases

The lymphatic vascular system is actively involved in tissue fluid homeostasis, immune surveillance and fatty acid transport. Pathological conditions can arise from injury to the lymphatics, or they can be recruited in the context of cancer to facilitate metastasis. Protein tyrosine kinases are central players in signal transduction networks and regulation of cell behavior. In the lymphatic endothelium, tyrosine kinases are involved in processes such as the maintenance of existing lymphatic vessels, growth and maturation of new vessels and modulation of their identity and function. As such, they are attractive targets for both existing inhibitors and the development of new inhibitors which affect lymphangiogenesis in pathological states such as cancer. RNAi screening provides an opportunity to identify the functional role of tyrosine kinases in the lymphatics. This review will discuss the role of tyrosine kinases in lymphatic biology and the potential use of inhibitors for anti-lymphangiogenic therapy

Watershed Management Planning for the Murrells Inlet Estuary using GIS: Delineation, Assessment, Identification, and Solutions for Fecal Coliform Loading,

2014 S.C. Water Resources Conference - Informing Strategic Water Planning to Address Natural Resource, Community and Economic Challenge

Culture for Sale? An Exploratory Study of the Crow Fair

This paper describes an ethnographically-oriented participant-observation study conducted during the annual Crow Fair, held in south central Montana. Data collected included audio-recorded interviews with participants, participant observations, photographic and video recordings. Narrative interviews were transcribed and analyzed using the constant comparison method. Multiple data sources improved the veracity of this study through triangulation, and four themes emerged from the data: commercialization, alcohol abuse, spirituality, and community. The researchers discuss these themes and their conclusions regarding the selling of Native American culture as a form of cultural transmission. Theme analysis revealed the researchers recognized that the principal researcher had changed his view of the Crow Fair as being frivolous to having a deeper purpose and meaning to participants

Transcription factor redundancy and tissue-specific regulation: Evidence from functional and physical network connectivity

Two major transcriptional regulators of Caenorhabditis elegans bodywall muscle (BWM) differentiation, hlh-1 and unc-120, are expressed in muscle where they are known to bind and regulate several well-studied muscle-specific genes. Simultaneously mutating both factors profoundly inhibits formation of contractile BWM. These observations were consistent with a simple network model in which the muscle regulatory factors drive tissue-specific transcription by binding selectively near muscle-specific targets to activate them. We tested this model by measuring the number, identity, and tissue-specificity of functional regulatory targets for each factor. Some joint regulatory targets (218) are BWM-specific and enriched for nearby HLH-1 binding. However, contrary to the simple model, the majority of genes regulated by one or both muscle factors are also expressed significantly in non-BWM tissues. We also mapped global factor occupancy by HLH-1, and created a genetic interaction map that identifies hlh-1 collaborating transcription factors. HLH-1 binding did not predict proximate regulatory action overall, despite enrichment for binding among BWM-specific positive regulatory targets of hlh-1. We conclude that these tissue-specific factors contribute much more broadly to the transcriptional output of muscle tissue than previously thought, offering a partial explanation for widespread HLH-1 occupancy. We also identify a novel regulatory connection between the BWM-specific hlh-1 network and the hlh-8/twist nonstriated muscle network. Finally, our results suggest a molecular basis for synthetic lethality in which hlh-1 and unc-120 mutant phenotypes are mutually buffered by joint additive regulation of essential target genes, with additional buffering suggested via newly identified hlh-1 interacting factors