Carbon Monoxide Exposure and Human Health

The primary objective of this report is to provide detailed information on the health effects of carbon monoxide. With this information, the community can judge for itself what action is deemed necessary to maintain or improve the health of its residents

Tier One interventions at Tier Three

The DeKalb/Rockdale GNETS program has been implementing PBIS for over three years. The basis of our program are our tier one strategies, a token economy, points and levels system, and school-wide special events. Token economies and point systems are in place at both centers as well as our elementary and middle transition programs. The levels and school-wide special events are only implemented at the two centers. During this interactive presentation, our tier one interventions will be explained in detail and ways of adopting these strategies in various settings will be discussed. Implementation fidelity will also be discussed, along with teacher buy-in, and student buy-in. This presentation will provide realistic implementation strategies for tier one interventions across settings

Experimental compaction of anisotropic granular media

We report on experiments to measure the temporal and spatial evolution of packing arrangements of anisotropic and weakly confined granular material, using high-resolution $\gamma$-ray adsorption. In these experiments, the particle configurations start from an initially disordered, low-packing-fraction state and under vertical solicitations evolve to a dense state. We find that the packing fraction evolution is slowed by the grain anisotropy but, as for spherically shaped grains, can be well fitted by a stretched exponential. For a given type of grains, the characteristic times of relaxation and of convection are found to be of the same order of magnitude. On the contrary compaction mechanisms in the media strongly depend on the grain anisotropy.Comment: to appear in the european physical journal E (EPJE

A label-free mass spectrometry method for the quantification of protein isotypes

Successful quantitative mass spectrometry (MS) requires strategies to link the mass spectrometer response to the analyte abundance, with the response being dependent on more factors than just analyte abundance. Label-dependent strategies rely on the incorporation of an isotopically labeled internal standard into the sample. Current label-free strategies (performed without internal standards) are useful for analyzing samples that are unsuitable for isotopic labeling but are less accurate. Here we describe a label-free technique applicable to analysis of products from related genes (isotypes). This approach enables the invariant tryptic peptide sequences within the family to serve as “built-in” internal standards and the isotype-specific peptide sequences to report the amount of the various isotypes. A process of elimination segregates reliably trypsin-released standard and reporter peptides from unreliably released peptides. The specific MS response factors for these reporter and standard peptides can be determined using synthetic peptides. Analysis of HeLa tubulin digests revealed peptides from βI-, βII-, βIII-, βIVb-, and βV-tubulin, eight of which were suitable; along with five standard peptides for quantification of the β-tubulin isotypes. To show the utility of this method, we determined that βI-tubulin represented 77% and βIIItubulin represented 3.2% of the total HeLa β-tubulin

Functionality and the evolution of marginal stability in proteins: Inferences from lattice simulations

It has been known for some time that many proteins are marginally stable. This has inspired several explanations. Having noted that the functionality of many enzymes is correlated with subunit motion, flexibility, or general disorder, some have suggested that marginally stable proteins should have an evolutionary advantage over proteins of differing stability. Others have suggested that stability and functionality are contradictory qualities, and that selection for both criteria results in marginally stable proteins, optimised to satisfy the competing design pressures. While these explanations are plausible, recent research simulating the evolution of model proteins has shown that selection for stability, ignoring any aspects of functionality, can result in marginally stable proteins because of the underlying makeup of protein sequence-space. We extend this research by simulating the evolution of proteins, using a computational protein model that equates functionality with binding and catalysis. In the model, marginal stability is not required for ligand-binding functionality and we observe no competing design pressures. The resulting proteins are marginally stable, again demonstrating that neutral evolution is sufficient for explaining marginal stability in observed proteins

Pedagogical Considerations that May Encourage Character Development in a Distance Education Course

The aims espoused by institutions of higher education often entail the development of students’ character. Rarely, however, are these character development aims connected to the unique design and delivery of distance education programs, and the research literature that explores the moral and character development aspects of distance education is sparse. This case study examines instructor and student perceptions of approaches, instructional methods, and other factors that contributed to perceived character development in a fantasy literature distance education course. The findings indicate that the instructor and students perceived myriad kinds of character development and corresponding approaches and methods for bringing about such development in the context of the course. This article considers possible implications for character development in the context of distance education and directions for future research

The Phenomenon of Character Development in a Distance Education Course

Rarely are character development-related aims espoused by higher education reflected in the design and delivery of distance education programs. Further, literature exploring the character development aspects of distance education is sparse. This study finds that the instructor and students in a fantasy literature distance course perceived myriad kinds of character development related to performance, moral, relational, and spiritual character traits and strengths. This paper considers implications for character development in distance education and directions for future research

An Economic Analysis of Carbon Sequestration for Wheat and Grain Sorghum Production in Kansas

This study examined the economic potential with and without carbon credit payments of two crop and tillage systems in South Central Kansas that could reduce carbon dioxide emissions and sequester carbon in the soil. Experiment station cropping practices, yield data, and soil carbon data for continuously cropped wheat and grain sorghum produced with conventional tillage and no-tillage from1986 to 1995 were used to determine soil carbon changes and to develop enterprise budgets to determine expected net returns for a typical dryland farm in South Central Kansas. No-till had lower net returns because of lower yields and higher overall costs. Both crops produced under no-till had higher annual soil C gains than under conventional tillage. Carbon credit payments may be critical to induce farm managers to use cropping practices, such as no-till, that sequester soil carbon. The carbon credit payments needed will be highly dependent on cropping system production costs, especially herbicide costs, which substitute for tillage as a means of weed control. The C values estimated in this study that would provide an incentive to adopt no-tillage range from $0 to$95.991ton/year, depending upon the assumption about herbicide costs. In addition, if producers were compensated for other environmental benefits associated with no-till, carbon credits could be reduced.carbon credit value, carbon sequestration, grain sorghum, no-tillage, wheat, Crop Production/Industries,

Derived Carbon Credit Values for Carbon Sequestration: Do CO2 Emissions From Production Inputs Matter?

Environmental Economics and Policy,