Replacing the Social Security Tax with a Value-Added Tax: Policy Perspectives

On October 22, 1979, Representative Al Ullman (D-Ore.), then Chairman of the House Ways and Means Committee, introduced the Tax Restructuring Act of 1979, which would have lowered the rates of the individual income, corporate income and social security taxes along with certain other tax benefits and would have replaced the lost revenues from such reductions with the revenues from a 10% value-added tax (VAT). The introduction of the bill followed a speech delivered by Sen. Russell B. Long (D-La.), then Chairman of the Senate Finance Committee, at the 1978 Tulane Tax Institute, in which he advocated an overhaul of the tax system similar to the proposals contained in Ullman\u27s bill. Although there was nothing particularly novel in the proposals of Long and Ullman, the mere fact that the two members of Congress with the most influence over tax legislation were advocating a major overhaul of the entire tax system was enough to spark a lively debate on the merits of substituting a value-added tax for part or all of the components making up the present federal tax system in the United States

The Ursinus Weekly, May 6, 1940

Speaker Clinchy shows threat of ideology clash • Open house program includes track meet, exhibits, exams • Penn invites three to bicentennial this fall • Seniors revolutionize program of Class Day • Le Art\u27s Ambassadors to play for May hop • King\u27s daughters is feature of Mothers\u27 Day entertainment • The lovable Sycamore family comes to Ursinus • Dubuque wins contest • Lantern deadline announced • Review of Ursinus athletic program • Counseling system used aids student adjustment • Placement tests indicate high ranking of Ursinus freshmen • Application of three tests to educational institutions should precede matriculation • Ursinus graduates win med. school success • Lookin\u27 at Ursinus and where we live • Footprints is novel theme featured as Ruby makes earliest debut in years • French, German clubs to give joint doggie roast and sing • Phys Ed. Club elects • Manuscript Club elects Shisler • Varsity acquires wins from Leb. Valley, Swarthmore; J.V.\u27s lose to Brown Prep • Raban breaks Ursinus record as bears lose • Over 500 compete in scholastic meet here • Racqueteers top Swarthmore co-eds; men lose to F. and M. • Hillegass, Wood elected heads of forum group • Showalter inducted into office at banquet of student council • Dr. Stoner to address pre-meds. on Tuesday • Mauchly attends Washington convention of physics society • Bruehl talks to Newman Club • Tau Sig\u27s exhibit hobbies • Dr. Russell Sturgis discusses cultural aspects of sciences • Fraternity election resultshttps://digitalcommons.ursinus.edu/weekly/1843/thumbnail.jp

Evaluating alternative gait strategies using evolutionary robotics

Evolutionary robitics is a branch of artificial intelligence concerned with the automatic generation of autonomous robots. Usually the form of the robit is predefined an various computational techniques are used to control the machine's behaviour. One aspect is the spontaneous generation of walking in legged robots and this can be used to investigate the mechanical requiements for efficient walking in bipeds. This paper demonstrates a bipedal simulator that spontaneously generates walking and running gaits. The model can be customized to represent a range of hominoid morphologies and used to predict performance paramets such as preferred speed and metabolic energy cost. Because it does not require any motion capture data it is particularly suitable for investigating locomotion in fossil animals. The predictoins for modern humans are highly accurate in terms of energy cost for a given speend and thus the values predicted for other bipeds are likely to be good estimates. To illustrate this the cost of transport is calculated for Australopithecus afarensis. The model allows the degree of maximum extension at the knee to be varied causing the model to adopt walking gaits varying from chimpanzee-like to human=like. The energy costs associated with these gait choices can thus be calculated and this information used to evaluate possible locomotor strategies in early hominid

Effects of Electromagnetic Fields on Fish and Invertebrates

In this progress report, we describe the preliminary experiments conducted with three fish and one invertebrate species to determine the effects of exposure to electromagnetic fields. During fiscal year 2010, experiments were conducted with coho salmon (Onchrohychus kisutch), California halibut (Paralicthys californicus), Atlantic halibut (Hippoglossus hippoglossus), and Dungeness crab (Cancer magister). The work described supports Task 2.1.3: Effects on Aquatic Organisms, Subtask 2.1.3.1: Electromagnetic Fields

Public Response to Community Mitigation Measures for Pandemic Influenza

Results from a national survey indicated that most persons would follow public health officials’ guidelines

Concert recording 2018-11-13

[Track 1]. Douzes etudes pour Caisse Claire. No. 1 / Jacques Delecluse -- [Track 2]. Ghost garden / Adam Hopper -- [Track 3]. Rotation no. 4 / Eric Sammut -- [Track 4]. Nine French-American rudimental solos. No. 6 / Unknown -- [Track 5]. Advanced studies for snare drum. No. 3 / Mitchell Peters -- [Track 6]. Tempest / Todd Ukena -- [Track 7]. Excerpt from Northern lights / Eric Ewazen -- [Track 8]. Caleidoscópio / Gene Koschinksi -- [Track 9]. Advanced studies for snare drum. No. 1 / Peters -- [Track 10]. Sweet dreams from Album for the young / Tchaikovsky arranged by L.H. Stevens -- [Track 11]. Furioso and valse in D minor / Earl Hatch -- [Track 12]. Pratt\u27s taps / William Schinstine -- [Track 13]. Max / J.C. Combs -- [Track 14]. Raga no. 1 / William Cahn -- [Track 15]. Sechs Miniaturen. No. 3 / Matthias Schmitt -- [Track 16]. Eden / Adam Miller -- [Track 17]. Four pieces for timpani. Mvts. 3 & 4 / John Bergamo -- [Track 18]. Swerve / Gene Kaschinski -- [Track 19]. White knuckle stroll / Casey Cangelosi -- [Track 20]. Evergreen / Benjamin Finley -- [Track 21]. Time remembered / Branden Steinmetz

Concert recording 2019-04-16

[Track 1]. Rotation #2 / Eric Sammut -- [Track 2]. Pines of Rome mvt 1 / Ottorino Respighi -- [Track 3]. Chart #2 / Fernando Valencia -- [Track 4]. Chopstakovich / Jesse Sieff -- [Track 5]. Drei Skizzen mvt. III / Matthias Schmitt -- [Track 6]. Sonata no. 1 for G in violoncello. Prelude [Track 7]. Sarabande [Track 8]. Courante / J.S. Bach -- [Track 9]. #1 from Douze Etudes / Jacques Delecluse -- [Track 10]. The offering / Michael Burritt -- [Track 11]. Prelude and blues / Ney Rosauro -- [Track 12]. Danny boy / traditional arranged by Brian Mueller -- [Track 13]. Ransom / Mark Ford -- [Track 14]. Sonata for timpani mvt III / John Beck -- [Track 15]. Dr. Gradus ad Parnassum / Claude Debussy arranged by Paul Bissell -- [Track 16]. Etude #1 / Vic Firth -- [Track 17]. Highlights from Northern lights / Eric Ewazen -- [Track 18]. Jesus loves me / Chad Floyd -- [Track 19]. Faded lines / Andrea Venet - [Track 20]. Triplets / George Hamilton Green arranged by Bob Becker -- [Track 21]. Girlfriends medley / Bob Becker -- [Track 22]. Selections from Oru Secu. Guaguancó [Track 23]. Guarapachangueo / Traditional trans. Valencia

Phase II Study of Bortezomib and Pegylated Liposomal Doxorubicin in the Treatment of Metastatic Breast Cancer

Based on preclinical studies and a phase I trial of the combination of bortezomib and pegylated liposomal doxorubicin (PLD), which both showed activity in breast cancer, we conducted a phase II study of this regimen in patients with metastatic breast cancer

TBCRC 019: A phase II trial of nanoparticle albumin-bound paclitaxel with or without the anti-death receptor 5 monoclonal antibody tigatuzumab in patients with triple negative breast cancer

Purpose: Tigatuzumab (TIG), an agonistic anti-DR5 antibody, triggers apoptosis in DR5+ human tumor cells without crosslinking. TIG has strong in vitro/in vivo activity against basal-like breast cancer cells enhanced by chemotherapy agents. This study evaluates activity of TIG and chemotherapy in patients with metastatic triple-negative breast cancer (TNBC). Experimental Design: Randomized 2:1 phase II trial of albumin-bound paclitaxel (nab-PAC) ± TIG in patients with TNBC stratified by prior chemotherapy. Patients received nab-PAC weekly × 3 ± TIG every other week, every 28 days. Primary objective was within-arm objective response rate (ORR). Secondary objectives were safety, progression-free survival (PFS), clinical benefit, and TIG immunogenicity. Metastatic research biopsies were required. Results: Among 64 patients (60 treated; TIG/nab-PAC n = 39 and nab-PAC n = 21), there were 3 complete remissions (CR), 8 partial remissions (PR; 1 almost CR), 11 stable diseases (SD), and 17 progressive diseases (PD) in the TIG/nab-PAC arm (ORR, 28%), and no CRs, 8 PRs, 4 SDs, and 9 PDs in the nab-PAC arm (ORR, 38%). There was a numerical increase in CRs and several patients had prolonged PFS (1,025+, 781, 672, 460, 334) in the TIG/nab-PAC arm. Grade 3 toxicities were 28% and 29%, respectively, with no grade 4–5. Exploratory analysis suggests an association of ROCK1 gene pathway activation with efficacy in the TIG/nab-PAC arm. Conclusions: ORR and PFS were similar in both. Preclinical activity of TIG in basal-like breast cancer and prolonged PFS in few patients in the combination arm support further investigation of anti-DR5 agents. ROCK pathway activation merits further evaluation