160 research outputs found

    Ordovician chitinous hydroids from Hudson Strait, District of Franklin, Northwest Territories

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    Chitinous hydroids are documented for the first time from the Upper Ordovician of Eastern Canada, and for the fourth time from North American rocks. One hydrosome branch segment is provisionally attributed to Rhabdohydra Kozlowski. The excellent three dimensional preservation shows the periderm is layered and vesiculate. Periderm thinning, present in Recent chitinous hydroids, is also noted for Ordovician hydroids. RÉSUMÉ Une premiére signalisation, d'hydro ides chitineuses dans l’Ordovicien sup iérieur de l'Est du Canada vient s'ajouter aux trois documents deja issus de roches nord-ameiicaines. Un segment de rameau hydrosomal est rapporte' avec r iéserve au genre Rhabdohydra Kozlowski. line excellente conservation dans ses trois dimensions d iémontre que le p iériderme est vésiculeux et constitu ié de plusieurs couches. L'amincissement du p iériderme, ph iénom iène connu des hydroides chitineuses actuelles, se manifeste aussi chez les hydroides ordoviciennes

    Utilizing Gene Tree Variation to Identify Candidate Effector Genes in Zymoseptoria tritici

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    Zymoseptoria tritici is a host-specific, necrotrophic pathogen of wheat. Infection by Z. tritici is characterized by its extended latent period, which typically lasts two weeks, and is followed by extensive host cell death and rapid proliferation of fungal biomass. This work characterizes the level of genomic variation in 13 isolates for which we have measured virulence on 11 wheat cultivars with differential resistance genes. Between the reference isolate, IPO323, and the 13 Australian isolates we identified over 800,000 single nucleotide polymorphisms, of which ~10% had an effect on the coding regions of the genome. Furthermore we identified over 1700 probable presence/absence polymorphisms in genes across the Australian isolates using de novo assembly. Finally, we developed a gene tree sorting method that quickly identifies groups of isolates within a single gene alignment whose sequence haplotypes correspond with virulence scores on a single wheat cultivar. Using this method we have identified <100 candidate effector genes whose gene sequence correlates with virulence towards a wheat cultivar carrying a major resistance gene

    External vs. Innate: Sources of Resiliency Among Emerging Adults, Black Gay and Bisexual Men

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    The purpose of this research was to examine the main sources and origins of resiliency that are present among Black gay and bisexual men. Resiliency refers to one’s response to adversity and ability to positively adapt to difficult situations. Twenty participants ranging in age between 18-25 years old (M = 22.8 years, SD = 1.7 years) participated in a semi-structured interview. Participants indicated varying sources of resiliency, which they utilize to encounter hardships. Innate sources (i.e., I was born this way) and external sources (i.e., music, my grandmother’s spirit) were conveyed by participants as mechanisms to overcome adversity. The current findings seek to increase social understanding of the means through which these emerging adults overcome adversity, in effort to decrease social marginalization, stigmatization, and discrimination

    2-Amino-4,5,6,7-tetra­hydro­benzo[b]thio­phene-3-carbonitrile

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    The title compound, C9H10N2S, was synthesized according to Gewald procedures by the reaction of cyclo­hexa­none with malonitrile and sulfur in the presence morpholine. The cyclo­hexane ring adopts a half-chair conformation and the thio­phene ring is essentially planar (r.m.s. deviation = 0.05 Å). The crystal packing is stabilized by two inter­molecular N—H⋯N hydrogen bonds, which link the mol­ecules into centrosymmetric rings with graph-set motif R 2 2(12)

    Crafting communities: promoting inclusion, empowerment, and learning between older women

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    While social policy and planning documents are replete with ominous warnings about the cost of an ageing population, this article tells a different story about the productive and self-sustaining networks that exist among older women in the community who do craftwork. From our research conducted in Victoria, Australia during 2007&ndash;2008 we discovered a resilient and committed group of older women quietly and steadily contributing to community fundraising, building social networks, and providing learning opportunities to each other in diverse ways. Through our conversations with nine craftswomen we have been able to articulate clear links between the theory and models commonly espoused in the community development literature and the life-enriching practices used in organising informal community craft group activities. From our interviews with the older women we provide evidence of sustained participation, the generation of social capital, and the fostering of life-long learning. While none of the women we spoke to were trained in community development and did not use language commonly associated with feminist ideology, the relationship between the informal group work with principles of empowerment and self-efficacy were unmistakeable. We conclude with a discussion of the implications of our findings for critical social work practice.<br /

    Effect of Impurities on Pentacene Thin Film Growth for Field-Effect Transistors

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    Pentacenequinone (PnQ) impurities have been introduced into a pentacene source material at number densities from 0.001 to 0.474 to quantify the relative effects of impurity content and grain boundary structure on transport in pentacene thin-film transistors. Atomic force microscopy (AFM) and electrical measurements of top-contact pentacene thin-film transistors have been employed to directly correlate initial structure and final film structures, with the device mobility as a function of added impurity content. The results reveal a factor four decrease in mobility without significant changes in film morphology for source PnQ number fractions below ~0.008. For these low concentrations, the impurity thus directly influences transport, either as homogeneously distributed defects or by concentration at the otherwise-unchanged grain boundaries. For larger impurity concentrations, the continuing strong decrease in mobility is correlated with decreasing grain size, indicating an impurity-induced increase in the nucleation of grains during early stages of film growth.Comment: 18 pages, 4 Figures, 1 Tabl

    Super-silent FRET Sensor Enables Live Cell Imaging and Flow Cytometric Stratification of Intracellular Serine Protease Activity in Neutrophils

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    Abstract Serine proteases are released by neutrophils to act primarily as antimicrobial proteins but excessive and unbalanced serine protease activity results in serious host tissue damage. Here the synthesis of a novel chemical sensor based on a multi-branched fluorescence quencher is reported. It is super-silent, exhibiting no fluorescence until de-quenched by the exemplar serine protease human neutrophil elastase, rapidly enters human neutrophils, and is inhibited by serine protease inhibitors. This sensor allows live imaging of intracellular serine protease activity within human neutrophils and demonstrates that the unique combination of a multivalent scaffold combined with a FRET peptide represents a novel and efficient strategy to generate super-silent sensors that permit the visualisation of intracellular proteases and may enable point of care whole blood profiling of neutrophils
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