991 research outputs found

    Convergence and multiplicities for the Lempert function

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    Given a domain Ω⊂C\Omega \subset \mathbb C, the Lempert function is a functional on the space Hol (\D,\Omega) of analytic disks with values in Ω\Omega, depending on a set of poles in Ω\Omega. We generalize its definition to the case where poles have multiplicities given by local indicators (in the sense of Rashkovskii's work) to obtain a function which still dominates the corresponding Green function, behaves relatively well under limits, and is monotonic with respect to the indicators. In particular, this is an improvement over the previous generalization used by the same authors to find an example of a set of poles in the bidisk so that the (usual) Green and Lempert functions differ.Comment: 24 pages; many typos corrected thanks to the referee of Arkiv for Matemati

    Development and validation of two self-reported tools for insulin resistance and hypertension risk assessment in a European cohort : the Feel4Diabetes-study

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    Early identification of type 2 diabetes mellitus (T2DM) and hypertension (HTN) risk may improve prevention and promote public health. Implementation of self-reported scores for risk assessment provides an alternative cost-effective tool. The study aimed to develop and validate two easy-to-apply screening tools identifying high-risk individuals for insulin resistance (IR) and HTN in a European cohort. Sociodemographic, lifestyle, anthropometric and clinical data obtained from 1581 and 1350 adults (baseline data from the Feel4Diabetes-study) were used for the European IR and the European HTN risk assessment index respectively. Body mass index, waist circumference, sex, age, breakfast consumption, alcohol, legumes and sugary drinks intake, physical activity and sedentary behavior were significantly correlated with Homeostatic Model Assessment of IR (HOMA-IR) and/or HTN and incorporated in the two models. For the IR index, the Area Under the Curve (AUC), sensitivity and specificity for identifying individuals above the 75th and 95th of HOMA-IR percentiles were 0.768 (95%CI: 0.721–0.815), 0.720 and 0.691 and 0.828 (95%CI: 0.766–0.890), 0.696 and 0.778 respectively. For the HTN index, the AUC, sensitivity and specificity were 0.778 (95%CI: 0.680–0.876), 0.667 and 0.797. The developed risk assessment tools are easy-to-apply, valid, and low-cost, identifying European adults at high risk for developing T2DM or having HTN

    STOVE: Seed treatments for organic vegetable production

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    The aim of the EU-financed research project „STOVE“ (Seed Treatments for Organic Vegetable Production) is to evaluate different methods potentially suited for seed treatment of vegetables in organic farming regarding their efficacy, to optimise these methods, and where feasible to combine them with each other. Scientists from seven European research institutions and a producer of organic vegetable seeds carry out the project

    Making Code Voting Secure against Insider Threats using Unconditionally Secure MIX Schemes and Human PSMT Protocols

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    Code voting was introduced by Chaum as a solution for using a possibly infected-by-malware device to cast a vote in an electronic voting application. Chaum's work on code voting assumed voting codes are physically delivered to voters using the mail system, implicitly requiring to trust the mail system. This is not necessarily a valid assumption to make - especially if the mail system cannot be trusted. When conspiring with the recipient of the cast ballots, privacy is broken. It is clear to the public that when it comes to privacy, computers and "secure" communication over the Internet cannot fully be trusted. This emphasizes the importance of using: (1) Unconditional security for secure network communication. (2) Reduce reliance on untrusted computers. In this paper we explore how to remove the mail system trust assumption in code voting. We use PSMT protocols (SCN 2012) where with the help of visual aids, humans can carry out mod  10\mod 10 addition correctly with a 99\% degree of accuracy. We introduce an unconditionally secure MIX based on the combinatorics of set systems. Given that end users of our proposed voting scheme construction are humans we \emph{cannot use} classical Secure Multi Party Computation protocols. Our solutions are for both single and multi-seat elections achieving: \begin{enumerate}[i)] \item An anonymous and perfectly secure communication network secure against a tt-bounded passive adversary used to deliver voting, \item The end step of the protocol can be handled by a human to evade the threat of malware. \end{enumerate} We do not focus on active adversaries

    Estimating preharvest density, adult sex ratio, and fecundity of white-tailed deer using noninvasive sampling techniques

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    Adult sex ratio and fecundity (juveniles per female) are key population parameters in sustainable wildlife management, but inferring these requires abundance estimates of at least three age/sex classes of the population (male and female adults and juveniles). Prior to harvest, we used an array of 36 wildlife camera traps during 2 and 3 weeks in the early autumn of 2016 and 2017, respectively. We recorded white-tailed deer adult males, adult females, and fawns from the pictures. Simultaneously, we collected fecal DNA (fDNA) from 92 20 m x 20 m plots placed in 23 clusters of four plots between the camera traps. We identified individuals from fDNA samples with microsatellite markers and estimated the total sex ratio and population density using spatial capture-recapture (SCR). The fDNA-SCR analysis concluded equal sex ratio in the first year and female bias in the second year, and no difference in space use between sexes (fawns and adults combined). Camera information was analyzed in a spatial capture (SC) framework assuming an informative prior for animals' space use, either (a) as estimated by fDNA-SCR (same for all age/sex classes), (b) as assumed from the literature (space use of adult males larger than adult females and fawns), or (c) by inferring adult male space use from individually identified males from the camera pictures. These various SC approaches produced plausible inferences on fecundity, but also inferred total density to be lower than the estimate provided by fDNA-SCR in one of the study years. SC approaches where adult male and female were allowed to differ in their space use suggested the population had a female-biased adult sex ratio. In conclusion, SC approaches allowed estimating the preharvest population parameters of interest and provided conservative density estimates

    The extent of neuroradiological findings in COVID-19 shows correlation with blood biomarkers, Glasgow coma scale score and days in intensive care

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    Background and purpose: A wide range of neuroradiological findings has been reported in patients with coronavirus disease 2019 (COVID-19), ranging from subcortical white matter changes to infarcts, haemorrhages and focal contrast media enhancement. These have been descriptively but inconsistently reported and correlations with clinical findings and biomarkers have been difficult to extract from the literature. The purpose of this study was to quantify the extents of neuroradiological findings in a cohort of patients with COVID-19 and neurological symptoms, and to investigate correlations with clinical findings, duration of intensive care and biomarkers in blood. Material and methods: Patients with positive SARS-CoV-2 and at least one new-onset neurological symptom were included from April until July 2020. Nineteen patients were examined regarding clinical symptoms, biomarkers in blood and MRI of the brain. In order to quantify the MRI findings, a semi-quantitative neuroradiological severity scale was constructed a priori, and applied to the MR images by two specialists in neuroradiology. Results and conclusions: The score from the severity scale correlated significantly with blood biomarkers of CNS injury (glial fibrillary acidic protein, total-tau, ubiquitin carboxyl-terminal hydrolase L1) and inflammation (C-reactive protein), Glasgow Coma Scale score, and the number of days spent in intensive care. The underlying radiological assessments had inter-rater agreements of 90.5%/86% (for assessments with 2/3 alternatives). Total intraclass correlation was 0.80. Previously reported neuroradiological findings in COVID-19 have been diverse and heterogenous. In this study, the extent of findings in MRI examination of the brain, quantified using a structured report, shows correlation with relevant biomarkers

    Maternal sleep quality during pregnancy is associated with neonatal auditory ERPs

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    Poor maternal sleep quality during pregnancy may act as a prenatal stress factor for the fetus and associate with neonate neurocognition, for example via fetal programming. The impacts of worsened maternal sleep on neonatal development and, more specifically on neonatal auditory brain responses, have not been studied. A total of 155 mother-neonate dyads drawn from the FinnBrain Birth Cohort Study participated in our study including maternal self-report questionnaires on sleep at gestational week 24 and an event-related potential (ERP) measurement among 1-2-day-old neonates. For sleep quality assessment, the Basic Nordic Sleep Questionnaire (BNSQ) was used and calculated scores for (1) insomnia, (2) subjective sleep loss and (3) sleepiness were formed and applied in the analyses. In the auditory ERP protocol, three emotionally uttered pseudo words (in happy, angry and sad valence) were presented among neutrally uttered pseudo words. To study the relations between prenatal maternal sleep quality and auditory emotion-related ERP responses, mixed-effects regression models were computed for early (100-200 ms) and late (300-500 ms) ERP response time-windows. All of the selected BNSQ scores were associated with neonatal ERP responses for happy and angry emotion stimuli (sleep loss and sleepiness in the early, and insomnia, sleep loss and sleepiness in the late time-window). For sad stimuli, only maternal sleep loss predicted the neonatal ERP response in the late time-window, likely because the overall ERP was weakest in the sad condition. We conclude that maternal sleep quality during pregnancy is associated with changes in neonatal auditory ERP responses.Peer reviewe

    The Combined Roles of Moral Emotion and Moral Rules in Explaining Acts of Violence Using a Situational Action Theory Perspective

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    The roles of shame and guilt, and their relationships to empathy, have not been modeled adequately as key factors in moral decision-making in the study of violence. The role of moral emotion has been neglected in existing criminological research and this study seeks to develop current explanations of the comprehensive myriad of factors that play a role in moral crime decision-making. This research will test the different roles of empathy, shame, and guilt in violence decision-making using a situational action theory (SAT) perspective. Data taken from the Peterborough Adolescent and Young Adult Development Study (PADS+), a longitudinal study with a large representative sample, provide quantitative questionnaire indices to enable comparison of a persistent and frequent violent offender subsample (N = 48) with the remaining PADS+ study sample (N = 607). A striking majority of violent offenders report that they do not think it is wrong to commit violence, and do not care about it, that is, they lack shame and guilt, and report that violence comes as a morally acceptable and natural action alternative. Furthermore, violent offenders do not register the predicament of their victims; there is a distinct lack of empathy. This article demonstrates a key finding which has rarely been explored to date; regression analyses reveal an interaction effect whereby individuals with weak shame and guilt, combined specifically with weak moral rules, are more likely to commit acts of violence. The study findings provide strong support for the SAT of the role of weak morality in violence decision-making. To reduce the possibility of crime being seen as an action alternative, moral development programs should be developed and administered in childhood
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