Face-on accretion onto a protoplanetary disc

Globular clusters (GCs) are known to harbor multiple stellar populations. To explain these observations Bastian et al. suggested a scenario in which a second population is formed by the accretion of enriched material onto the low-mass stars in the initial GC population. The idea is that the low-mass, pre-main sequence stars sweep up gas expelled by the massive stars of the same generation into their protoplanetary disc as they move through the GC core. We perform simulations with 2 different smoothed particle hydrodynamics codes to investigate if a low-mass star surrounded by a protoplanetary disc can accrete the amount of enriched material required in this scenario. We focus on the gas loading rate onto the disc and star as well as on the lifetime of the disc. We find that the gas loading rate is a factor of 2 smaller than the geometric rate, because the effective cross section of the disc is smaller than its surface area. The loading rate is consistent for both codes, irrespective of resolution. The disc gains mass in the high resolution runs, but loses angular momentum on a time scale of 10^4 yrs. Two effects determine the loss of (specific) angular momentum in our simulations: 1) continuous ram pressure stripping and 2) accretion of material with no azimuthal angular momentum. Our study and previous work suggest that the former, dominant process is mainly caused by numerical rather than physical effects, while the latter is not. The latter process causes the disc to become more compact, increasing the surface density profile at smaller radii. The disc size is determined in the first place by the ram pressure when the flow first hits the disc. Further evolution is governed by the decrease in the specific angular momentum of the disc. We conclude that the size and lifetime of the disc are probably not sufficient to accrete the amount of mass required in Bastian et al.'s scenario.Comment: Accepted for publication in A&A, 15 pages, 5 figures, 4 table

Fast But Not Furious. When Sped Up Bit Rate of Information Drives Rule Induction

The language abilities of young and adult learners range from memorizing specific items to finding statistical regularities between them (item-bound generalization) and generalizing rules to novel instances (category-based generalization). Both external factors, such as input variability, and internal factors, such as cognitive limitations, have been shown to drive these abilities. However, the exact dynamics between these factors and circumstances under which rule induction emerges remain largely underspecified. Here, we extend our information-theoretic model (Radulescu et al., 2019), based on Shannon’s noisy-channel coding theory, which adds into the “formula” for rule induction the crucial dimension of time: the rate of encoding information by a time-sensitive mechanism. The goal of this study is to test the channel capacity-based hypothesis of our model: if the input entropy per second is higher than the maximum rate of information transmission (bits/second), which is determined by the channel capacity, the encoding method moves gradually from item-bound generalization to a more efficient category-based generalization, so as to avoid exceeding the channel capacity. We ran two artificial grammar experiments with adults, in which we sped up the bit rate of information transmission, crucially not by an arbitrary amount but by a factor calculated using the channel capacity formula on previous data. We found that increased bit rate of information transmission in a repetition-based XXY grammar drove the tendency of learners toward category-based generalization, as predicted by our model. Conversely, we found that increased bit rate of information transmission in complex non-adjacent dependency aXb grammar impeded the item-bound generalization of the specific a_b frames, and led to poorer learning, at least judging by our accuracy assessment method. This finding could show that, since increasing the bit rate of information precipitates a change from item-bound to category-based generalization, it impedes the item-bound generalization of the specific a_b frames, and that it facilitates category-based generalization both for the intervening Xs and possibly for a/b categories. Thus, sped up bit rate does not mean that an unrestrainedly increasing bit rate drives rule induction in any context, or grammar. Rather, it is the specific dynamics between the input entropy and the maximum rate of information transmission

A Quasi-Universal Nonword Repetition Task as a Diagnostic Tool for Bilingual Children Learning Dutch as a Second Language.

PURPOSE: This study evaluated a newly developed quasi-universal nonword repetition task (Q-U NWRT) as a diagnostic tool for bilingual children with language impairment (LI) who have Dutch as a 2nd language. The Q-U NWRT was designed to be minimally influenced by knowledge of 1 specific language in contrast to a language-specific NWRT with which it was compared. METHOD: One hundred twenty monolingual and bilingual children with and without LI participated (30 per group). A mixed-design analysis of variance was used to investigate the effects of LI and bilingualism on the NWRTs. Receiver operating characteristic analyses were conducted to evaluate the instruments' diagnostic value. RESULTS: Large negative effects of LI were found on both NWRTs, whereas negative effects of bilingualism only occurred on the language-specific NWRT. Both instruments had high clinical accuracy in the monolingual group, but only the Q-U NWRT had high clinical accuracy in the bilingual group. CONCLUSIONS: This study indicates that the Q-U NWRT is a promising diagnostic tool to help identify LI in bilingual children learning Dutch as a 2nd language. The instrument was clinically accurate in both a monolingual and bilingual group of children and seems better able to disentangle LI from language disadvantage than more language-specific measures

Increased maternal TSH and decreased maternal FT4 are associated with a higher operative delivery rate in low-risk pregnancies:A prospective cohort study

Background:  The increasing number of operative deliveries is a topic of major concern in modern obstetrics. Maternal thyroid function is of known influence on many obstetric parameters. Our objective was to investigate a possible relation between maternal thyroid function, and operative deliveries. Secondary aim was to explore whether thyroid function was related to specific reasons for operative deliveries. Methods:  In this prospective cohort study, low-risk Caucasian women, pregnant of a single cephalic fetus were included. Women with known auto-immune disease, a pre-labour Caesarean section, induction of labour, breech presentation or preterm delivery were excluded. In all trimesters of pregnancy the thyroid function was assessed. Differences in mean TSH and FT4 were assessed using t-test. Mean TSH and FT4 levels for operative deliveries were determined by one way ANOVA. Repeated measurement analyses were performed (ANOVA), adjusting for BMI, partiy, maternal age and gestational age at delivery. Results:  In total 872 women were included, of which 699 (80.2 %) had a spontaneous delivery. At 36 weeks gestation women who had an operative delivery had a significantly higher mean TSH (1.63mIU/L versus 1.46mIU/L, p = 0.025) and lower mean FT4 (12.9pmol/L versus 13.3pmol/L, p = 0.007)) compared to women who had a spontaneous delivery. Mean TSH was significantly higher (p = 0.026) and mean FT4 significantly lower (p = 0.030) throughout pregnancy for women with an operative delivery due to failure to progress in second stage of labour, compared to women with a spontaneous delivery or operative delivery for other reasons. Conclusion:  Increased TSH and decreased FT4 seem to be associated with more operative vaginal deliveries and Caesarean sections. After adjusting for several confounders the association remained for operative deliveries due to failure to progress in second stage of labour, possibly to be explained by less efficient uterine action

Integrated voltage—current monitoring and control of gas metal arc weld magnetic ball-jointed open source 3-D printer

To provide process optimization of metal fabricating self-replicating rapid prototyper (RepRap) 3-D printers requires a low-cost sensor and data logger system to measure current (I) and voltage (V) of the gas metal arc welders (GMAW). This paper builds on previous open-source hardware development to provide a real-time measurement of welder I-V where the measuring circuit is connected to two analog inputs of the Arduino that is used to control the 3-D printer itself. Franklin firmware accessed through a web interface that is used to control the printer allows storing the measured values and downloading those stored readings to the user’s computer. To test this custom current and voltage monitoring device this study reports on its use on an upgraded all metal RepRap during the printing of aluminum alloy (ER1100, ER4043, ER4943, ER4047, and ER5356). The voltage and current data were analyzed on a per alloy basis and also layer-by-layer in order to evaluate the device’s efficacy as a monitoring device for 3-D printing and the results of the integrated design are discussed

Free and open-source control software for 3-D motion and processing

RepRap 3-D printers and their derivatives using conventional firmware are limited by: 1) requiring technical knowledge, 2) poor resilience with unreliable hardware, and 3) poor integration in complicated systems. In this paper, a new control system called Franklin, for CNC machines in general and 3-D printers specifically, is presented that enables web-based three dimensional control of additive, subtractive and analytical tools from any Internet connected device. Franklin can be set up and controlled entirely from a web interface; it uses a custom protocol which allows it to continue printing when the connection is temporarily lost, and allows communication with scripts

Components for a guidance document on groundwaterprotection

To improve the protection of the groundwater quality, policy should be more focused on local conditions, such as soil and groundwater. To increase this focus RIVM has proposed a generic framework for a groundwater protection policy that can be elaborated for each site in an area dossier. This dossier contains all relevant information on what measures can be developed on the basis of the desired effects. In the effort to achieve more uniformity and effectiveness in the Dutch groundwater protection policy, the Ministry of Housing, Spatial Planning and the Environment (VROM) is planning to derive a guidance document on groundwater protection. On commission of VROM, RIVM has elaborated several components to be used in describing policy, such as the risks of contamination with pathogens, the use of pesticides, the use of energy storage systems and actions on old contaminations. Additionally, RIVM has charted the legal demands set down by the new Water Framework Directive for the protection of industrial (private) abstractions for human consumption, such as the production of soda.Om de kwaliteit van het grondwater beter te kunnen beschermen moet het beleid meer worden toegespitst op lokale omstandigheden, zoals de natuurlijke opbouw van de bodem. Daarom pleit het RIVM voor het opstellen van een algemeen geldend kader voor grondwaterbeschermingsbeleid, dat per locatie nader kan worden uitgewerkt in een gebiedsdossier. Een gebiedsdossier bevat alle relevante informatie op basis waarvan een pakket maatregelen wordt ontwikkeld, gebaseerd op de gewenste effecten. Om meer uniformiteit en effectiviteit in het grondwaterbeschermingsbeleid te brengen is VROM van plan om in de komende jaren een Leidraad Grondwaterbescherming op te stellen. Het RIVM heeft in opdracht van het Ministerie van VROM een aantal van deze lacunes uitgewerkt, zoals de risico's van microbiologische besmetting, het gebruik van pesticiden, het toepassen van bodemenergiesystemen en het omgaan met van oudsher ontstane bodemverontreinigingen. Daarnaast heeft het instituut de juridische consequenties in beeld gebracht van de invoering van de Europese Kaderrichtlijn Water voor de bescherming van industriele grondwateronttrekkingen voor menselijke consumptie, zoals de productie van frisdranken

The Role of RUNX2 in Osteosarcoma Oncogenesis

Osteosarcoma is an aggressive but ill-understood cancer of bone that predominantly affects adolescents. Its rarity and biological heterogeneity have limited studies of its molecular basis. In recent years, an important role has emerged for the RUNX2 “platform protein” in osteosarcoma oncogenesis. RUNX proteins are DNA-binding transcription factors that regulate the expression of multiple genes involved in cellular differentiation and cell-cycle progression. RUNX2 is genetically essential for developing bone and osteoblast maturation. Studies of osteosarcoma tumours have revealed that the RUNX2 DNA copy number together with RNA and protein levels are highly elevated in osteosarcoma tumors. The protein is also important for metastatic bone disease of prostate and breast cancers, while RUNX2 may have both tumor suppressive and oncogenic roles in bone morphogenesis. This paper provides a synopsis of the current understanding of the functions of RUNX2 and its potential role in osteosarcoma and suggests directions for future study