24 research outputs found

    Nano and picosecond magnetization dynamics of weakly coupled CoFe/Cr/NiFe trilayers studied by a multitechnique approach

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    We present results on the magnetization dynamics in heterostructures of the CoFe/Cr/NiFe type. We have employed a combination of different layer-selective methods covering a broad range from quasistatic hysteresis measurements by x-ray magnetic circular dichroism (XMCD), over time-resolved photoemission electron microscopy (PEEM) at subnanosecond timescales to high-frequency ferromagnetic resonance (FMR) experiments. With increasing driving frequency, we found a different influence of the coupling between the two ferromagnetic layers on the dynamic behavior. Employing the spatial resolution of the PEEM method, we have been able to discern various dynamic responses in different regions of the sample that could be attributed to magnetodynamic processes with a different degree of coupling. In conjunction with the complementary FMR and XMCD measurements, we attribute the inhomogeneous influence of interlayer coupling to a shift from domain-wall-motion-dominated dynamics at low frequencies to precession-dominated dynamics at higher frequencies

    Testicular large B‐cell lymphoma is genetically similar to PCNSL and distinct from nodal DLBCL

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    Abstract Testicular large B‐cell lymphoma (TLBCL) is an infrequent and aggressive lymphoma arising in an immune‐privileged site and has recently been recognized as a distinct entity from diffuse large B‐cell lymphoma (DLBCL). We describe the genetic features of TLBCL and compare them with published series of nodal DLBCL and primary large B‐cell lymphomas of the CNS (PCNSL). We collected 61 patients with TLBCL. We performed targeted next‐generation sequencing, copy number arrays, and fluorescent in situ hybridization to assess chromosomal rearrangements in 40 cases with available material. Seventy percent of the cases showed localized stages. BCL6 rearrangements were detected in 36% of cases, and no concomitant BCL2 and MYC rearrangements were found. TLBCL had fewer copy number alterations (p < 0.04) but more somatic variants (p < 0.02) than nodal DLBCL and had more frequent 18q21.32‐q23 (BCL2) gains and 6q and 9p21.3 (CDKN2A/B) deletions. PIM1, MYD88L265P, CD79B, TBL1XR1, MEF2B, CIITA, EP300, and ETV6 mutations were more frequent in TLBCL, and BCL10 mutations in nodal DLBCL. There were no major genetic differences between TLBCL and PCNSL. Localized or disseminated TLBCL displayed similar genomic profiles. Using LymphGen, the majority of cases were classified as MCD. However, we observed a subgroup of patients classified as BN2, both in localized and disseminated TLBCL, suggesting a degree of genetic heterogeneity in the TLBCL genetic profile. TLBCL has a distinctive genetic profile similar to PCNSL, supporting its recognition as a separate entity from DLBCL and might provide information to devise targeted therapeutic approaches

    The NA49 Data Acquisition System

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    NA49 is a fixed-target, heavy-ion experiment at the 200 GeV/nucleon Pb beam of the SPS at CERN, expected to take data in late 1994. Because of the unprecedented number of charged particles (up to 2000) emerging from a single Pb-induced nuclear reaction at these energies, the demands on various parts of the experimental setup are extreme. For the data acquisition system a burst input data rate of 750 Mbyte/sec from more than 150,000 electronic channels has to be buffered and compressed to allow the recording of events to magnetic media at rates around 15 Mbyte/sec with reasonable effort and cost. © 1994 IEEE

    Physiognomic and chemical characters in wood as palaeoclimate proxies

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