1,981 research outputs found
Traffic Noise and the Hyperbolic Plane
We consider the problem of sound propagation in a wind. We note that the
rays, as in the absence of a wind, are given by Fermat's principle and show how
to map them to the trajectories of a charged particle moving in a magnetic
field on a curved space. For the specific case of sound propagating in a
stratified atmosphere with a small wind speed we show that the corresponding
particle moves in a constant magnetic field on the hyperbolic plane. In this
way we give a simple `straightedge and compass' method to estimate the
intensity of sound upwind and downwind. We construct Mach envelopes for moving
sources. Finally, we relate the problem to that of finding null geodesics in a
squashed anti-de Sitter spacetime and discuss the
symmetry of the problem from this point of view.Comment: Typos correcte
Validation, persuasion and recycling: capitalizing on the social ecology of newspaper use.
Journal ArticleTwo experiments used clinical validation to increase scrutiny of messages posted in public settings. The first experiment used a 2 (validation: no/yes) Ă 2 (persuasion: none/"it is important") factorial design to develop messages about newspaper recycling. The prompt (no validation/no persuasion) had little impact on newspaper recycling, but the other 3 signs all resulted in increased recycling while the signs were in place. After signs were removed, recycling remained significantly higher than baseline (marginally significant for validation/persuasion). At the end of the study, number of cognitions favoring recycling was significantly higher in the validation-only condition and was lower in the validation/persuasion condition. Experiment 2 tested whether signs would have more impact if they were sensitive to the social ecology of newspaper recycling; that is, readers' tendency to leave newspapers behind so others may read them. Messages based on a 2 (message: validation-only/validation plus persuasion) Ă 2 (ecology: no social ecology/social ecology) factorial design supported social ecology's importance. Furthermore, because of the increased sharing in the social ecology conditions, total numbers of newspapers used was significantly lower in those buildings. Validation only yielded sustained behavior change in both Experiments 1 and 2, supporting additional research on the question of whether validation can, by itself, lead to cognitive elaboration and self-persuasion. [ABSTRACT FROM AUTHOR
Superconductivity in hole-doped C60 from electronic correlations
We derive a model for the highest occupied molecular orbital band of a C60
crystal which includes on-site electron-electron interactions. The form of the
interactions are based on the icosahedral symmetry of the C60 molecule together
with a perturbative treatment of an isolated C60 molecule. Using this model we
do a mean-field calculation in two dimensions on the [100] surface of the
crystal. Due to the multi-band nature we find that electron-electron
interactions can have a profound effect on the density of states as a function
of doping. The doping dependence of the transition temperature can then be
qualitatively different from that expected from simple BCS theory based on the
density of states from band structure calculations
Observation of Parity Violation in the Omega-minus -> Lambda + K-minus Decay
The alpha decay parameter in the process Omega-minus -> Lambda + K-minus has
been measured from a sample of 4.50 million unpolarized Omega-minus decays
recorded by the HyperCP (E871) experiment at Fermilab and found to be [1.78 +/-
0.19(stat) +/- 0.16(syst)]{\times}10^{-2}. This is the first unambiguous
evidence for a nonzero alpha decay parameter, and hence parity violation, in
the Omega-minus -> Lambda + K-minus decay.Comment: 10 pages, 7 figure
Human and murine IFIT1 proteins do not restrict infection of negative-sense RNA viruses of the Orthomyxoviridae, Bunyaviridae, and Filoviridae families
UNLABELLED: Interferon-induced protein with tetratricopeptide repeats 1 (IFIT1) is a host protein with reported cell-intrinsic antiviral activity against several RNA viruses. The proposed basis for the activity against negative-sense RNA viruses is the binding to exposed 5\u27-triphosphates (5\u27-ppp) on the genome of viral RNA. However, recent studies reported relatively low binding affinities of IFIT1 for 5\u27-ppp RNA, suggesting that IFIT1 may not interact efficiently with this moiety under physiological conditions. To evaluate the ability of IFIT1 to have an impact on negative-sense RNA viruses, we infected Ifit1(-/-) and wild-type control mice and primary cells with four negative-sense RNA viruses (influenza A virus [IAV], La Crosse virus [LACV], Oropouche virus [OROV], and Ebola virus) corresponding to three distinct families. Unexpectedly, a lack of Ifit1 gene expression did not result in increased infection by any of these viruses in cell culture. Analogously, morbidity, mortality, and viral burdens in tissues were identical between Ifit1(-/-) and control mice after infection with IAV, LACV, or OROV. Finally, deletion of the human IFIT1 protein in A549 cells did not affect IAV replication or infection, and reciprocally, ectopic expression of IFIT1 in HEK293T cells did not inhibit IAV infection. To explain the lack of antiviral activity against IAV, we measured the binding affinity of IFIT1 for RNA oligonucleotides resembling the 5\u27 ends of IAV gene segments. The affinity for 5\u27-ppp RNA was approximately 10-fold lower than that for non-2\u27-O-methylated (cap 0) RNA oligonucleotides. Based on this analysis, we conclude that IFIT1 is not a dominant restriction factor against negative-sense RNA viruses.
IMPORTANCE: Negative-sense RNA viruses, including influenza virus and Ebola virus, have been responsible for some of the most deadly outbreaks in recent history. The host interferon response and induction of antiviral genes contribute to the control of infections by these viruses. IFIT1 is highly induced after virus infection and reportedly has antiviral activity against several RNA and DNA viruses. However, its role in restricting infection by negative-sense RNA viruses remains unclear. In this study, we evaluated the ability of IFIT1 to inhibit negative-sense RNA virus replication and pathogenesis both in vitro and in vivo. Detailed cell culture and animal studies demonstrated that IFIT1 is not a dominant restriction factor against three different families of negative-sense RNA viruses
Differences in plasma and peritoneal fluid proteomes identifies potential biomarkers associated with survival following strangulating small intestinal disease
DICER1 RNase IIIb domain mutations are infrequent in testicular germ cell tumours
Background: Testicular Germ Cell Tumours (TGCT) are the most frequently occurring malignancy in males from 15-45 years of age. They are derived from germ cells unable to undergo physiological maturation, although the genetic basis for this is poorly understood. A recent report showed that mutations in the RNase IIIb domain of DICER1, a micro-RNA (miRNA) processing enzyme, are common in non-epithelial ovarian cancers. DICER1 mutations were found in 60% of Sertoli-Leydig cell tumours, clustering in four codons encoding metal-binding sites. Additional analysis of 14 TGCT DNA samples identified one case that also contained a mutation at one of these sites. Findings. A number of previous studies have shown that DICER1 mutations are found in Q) within the RNase IIIb domain in one TGCT sample, which was predicted to disturb DICER1 function. Conclusion: Overall our findings suggest a mutation frequency in TGCTs of âŒ1%. We conclude therefore that hot-spot mutations, frequently seen in Sertoli-Leydig cell tumours, are not common in TGCTs
HyperCP: A high-rate spectrometer for the study of charged hyperon and kaon decays
The HyperCP experiment (Fermilab E871) was designed to search for rare
phenomena in the decays of charged strange particles, in particular CP
violation in and hyperon decays with a sensitivity of
. Intense charged secondary beams were produced by 800 GeV/c protons
and momentum-selected by a magnetic channel. Decay products were detected in a
large-acceptance, high-rate magnetic spectrometer using multiwire proportional
chambers, trigger hodoscopes, a hadronic calorimeter, and a muon-detection
system. Nearly identical acceptances and efficiencies for hyperons and
antihyperons decaying within an evacuated volume were achieved by reversing the
polarities of the channel and spectrometer magnets. A high-rate
data-acquisition system enabled 231 billion events to be recorded in twelve
months of data-taking.Comment: 107 pages, 45 Postscript figures, 14 tables, Elsevier LaTeX,
submitted to Nucl. Instrum. Meth.
Galactic cannibalism in the galaxy cluster C0337-2522 at z=0.59
According to the galactic cannibalism model, cD galaxies are formed in the
center of galaxy clusters by merging of massive galaxies and accretion of
smaller stellar systems: however, observational examples of the initial phases
of this process are lacking. We have identified a strong candidate for this
early stage of cD galaxy formation: a group of five elliptical galaxies in the
core of the X-ray cluster C0337-2522 at redshift z=0.59. With the aid of
numerical simulations, in which the galaxies are represented by N-body systems,
we study their dynamical evolution up to z=0; the cluster dark matter
distribution is also described as a N-body system. We find that a multiple
merging event in the considered group of galaxies will take place before z=0
and that the merger remnant preserves the Fundamental Plane and the
Faber-Jackson relations, while its behavior with respect to the Mbh-sigma
relation is quite sensitive to the details of black hole merging [abridged].Comment: 30 pages, 7 figures, MNRAS (accepted
Controlling quantum entanglement through photocounts
We present a protocol to generate and control quantum entanglement between
the states of two subsystems (the system ) by making measurements on
a third subsystem (the monitor ), interacting with . For
the sake of comparison we consider first an ideal, or instantaneous projective
measurement, as postulated by von Neumann. Then we compare it with the more
realistic or generalized measurement procedure based on photocounting on . Further we consider that the interaction term (between and
) contains a quantum nondemolition variable of and discuss
the possibility and limitations for reconstructing the initial state of from information acquired by photocounting on .Comment: 12 pages, 3 figures, accepted for publication in Phys. Rev
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