2,190 research outputs found
When Deaf Parents Adopt Deaf Children: An Investigation of the Concept of Adoptive Parent Entitlement in Deaf Adopted Families
The literature on Deaf people as parents in the past two decades is presented from both a culturally affirmative and a medical/pathological perspective (Jones, 1995; Lane, 1992, 1993; Meadow-Orlans, 1997; Spencer, Bodner-Johnson & Gutfreund, 1992), with the latter being more prevalent. It is rare to find an article that portrays Deaf people as highly competent and successful parents. It is even rarer to find an article that shows positive outcomes when Deaf parents adopt children (Shettle, 1997; White, 1997). The purpose of this qualitative study was to explore the experiences of adoptive parenthood from the viewpoint of seven Deaf mothers who shared their experiences in parenting a Deaf adopted child and their perceptions and recommendations to the adoption professionals they worked with
Body surface temperature responses to food restriction in wild and captive great tits
During winter at temperate and high latitudes, the low ambient temperatures, limited food supplies and short foraging periods mean small passerines show behavioural, morphological and physiological adaptations to reduce the risk of facing energy shortages. Peripheral tissues vasoconstrict in low ambient temperatures to reduce heat loss and cold injury. Peripheral vasoconstriction has been observed with food restriction in captivity but has yet to be explored in free-ranging animals. We experimentally food restricted both wild and captive great tits (Parus major) during winter months and measured surface temperatures of the bill and eye region using thermal imaging, to investigate whether birds show rapid local heterothermic responses, which may reduce their thermoregulatory costs when facing a perceived imminent food shortage. Our results of a continuously filmed wild population showed that bill temperature was immediately reduced in response to food restriction compared with when food was available ad libitum, an apparent autonomic response. Such immediacy implies a ‘pre-emptive’ response before the bird experiences any shortfalls in energy reserves. We also demonstrate temporal variation in vasoconstriction of the bill, with bill temperature gradually rising throughout the food restriction after the initial drop. Eye-region temperature in the wild birds remained at similar levels throughout food restriction compared with unrestricted birds, possibly reflecting the need to maintain steady circulation to the central nervous and visual systems. Our findings provide evidence that birds selectively allow the bill to cool when a predictable food supply is suddenly disrupted, probably as a means of minimising depletion of body reserves for a perceived future shortage in energy.</p
Transcriptional Regulation of Genes Involved in Zinc Uptake, Sequestration and Redistribution Following Foliar Zinc Application to Medicago sativa
Zinc (Zn) is an essential micronutrient for plants and animals, and Zn deficiency is a
widespread problem for agricultural production. Although many studies have been performed on
biofortification of staple crops with Zn, few studies have focused on forages. Here, the molecular
mechanisms of Zn transport in alfalfa (Medicago sativa L.) were investigated following foliar Zn
applications. Zinc uptake and redistribution between shoot and root were determined following
application of six Zn doses to leaves. Twelve putative genes encoding proteins involved in Zn
transport (MsZIP1-7, MsZIF1, MsMTP1, MsYSL1, MsHMA4, and MsNAS1) were identified and
changes in their expression following Zn application were quantified using newly designed RT-qPCR
assays. These assays are the first designed specifically for alfalfa and resulted in being more efficient
than the ones already available for Medicago truncatula (i.e., MtZIP1-7 and MtMTP1). Shoot and
root Zn concentration was increased following foliar Zn applications 0.1 mg plant1. Increased
expression of MsZIP2, MsHMA4, and MsNAS1 in shoots, and of MsZIP2 and MsHMA4 in roots was
observed with the largest Zn dose (10 mg Zn plant1). By contrast, MsZIP3 was downregulated in
shoots at Zn doses 0.1 mg plant1. Three functional gene modules, involved in Zn uptake by cells,
vacuolar Zn sequestration, and Zn redistribution within the plant, were identified. These results will
inform genetic engineering strategies aimed at increasing the efficiency of crop Zn biofortification
Assessment of urinary deoxynivalenol biomarkers in UK children and adolescents
© 2018 by the authors. Licensee MDPI, Basel, Switzerland. Deoxynivalenol (DON), the mycotoxin produced mainly by Fusarium graminearum and found in contaminated cereal-based foodstuff, has been consistently detected in body fluids in adults. Available data in children and adolescents are scarce. This study assessed urinary DON concentrations in children aged 3–9 years (n = 40) and adolescents aged 10–17 years (n = 39) in the UK. Morning urine samples were collected over two consecutive days and analysed for free DON (un-metabolised form), DON-glucuronides (DON-GlcA), deepoxy deoxynivalenol (DOM-1), and total DON (sum of free DON, DON-GlcA, and DOM-1). Total DON was detected in the urine of > 95% of children and adolescents on both days. Mean total DON concentrations (ng/mg creatinine) were 41.6 and 21.0 for children and adolescents, respectively. The greatest total DON levels were obtained in female children on both days (214 and 219 ng/mg creatinine on days 1 and 2, respectively). Free DON and DON-GlcA were detected in most urine specimens, whereas DOM-1 was not present in any sample. Estimation of dietary DON exposure suggested that 33–63% of children and 5–46% of adolescents exceeded current guidance regarding the maximum provisional tolerable daily intake (PMTDI) for DON. Although moderate mean urinary DON concentrations were shown, the high detection frequency of urinary DON, the maximum biomarker concentrations, and estimated dietary DON exposure are concerning
Advancing Administrative Supports for Research Development
Research intensive universities have raised the bar for all academic units, expecting them to increase research grants and contracts to support knowledge creation and scholarship. Similarly, performance requirements for faculty have changed, with annual reviews and tenure and promotion decisions weighting obtaining grants along with publication of scholarly products, teaching effectiveness, and service to the school, university and community. These expectations compel Deans and Directors of schools of social work to undertake new roles related to research development and administrative capacity building in order to help faculty and their units succeed.
Social work schools and departments must stay or become strategically positioned in their university or college, even as the context for research development has been dramatically altered as colleges and universities invest in the nanosciences or bio- technology rather than the social sciences. A 20 million that a robust research enterprise that a few schools of social work enjoy.
This paper highlights some of the opportunities, barriers, challenges, as well as stepping stones to success in the process of building research supports and infrastructures. Drawing upon presentations at recent meetings of the National Association of Deans and Directors of Schools of Social Work (NADD) that have been organized by the Institute of Social Work Research (IASWR), we feature several examples of approaches advancing supports for research development. Brief scenarios illustrating efforts underway at several schools depict challenging and often rewarding research capacity building endeavors. This paper presents the perspective of several Deans and Directors in the development of administrative research supports. The paper also features one model for a supportive research administration structure in the pre- and post-award environment
Synthetic high-density lipoprotein nanodisks for targeted withalongolide delivery to adrenocortical carcinoma
The Size and Shape of Voids in Three-Dimensional Galaxy Surveys
The sizes and shapes of voids in a galaxy survey depend not only on the
physics of structure formation, but also on the sampling density of the survey
and on the algorithm used to define voids. Using an N-body simulation with a
CDM power spectrum, we study the properties of voids in samples with different
number densities of galaxies, both in redshift space and in real space. When
voids are defined as regions totally empty of galaxies, their characteristic
volume is strongly dependent on sampling density; when they are defined as
regions whose density is 0.2 times the mean galaxy density, the dependence is
less strong. We compare two void-finding algorithms, one in which voids are
nonoverlapping spheres, and one, based on the algorithm of Aikio and Mahonen,
which does not predefine the shape of a void. Regardless of the algorithm
chosen, the characteristic void size is larger in redshift space than in real
space, and is larger for low sampling densities than for high sampling
densities. We define an elongation statistic Q which measures the tendency of
voids to be stretched or squashed along the line of sight. Using this
statistic, we find that at sufficiently high sampling densities (comparable to
the number densities of galaxies brighter than L_*), large voids tend to be
slightly elongated along the line of sight in redshift space.Comment: LaTex, 21 pages (including 7 figures), ApJ, submitte
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