17,794 research outputs found
Agglomeration Economies: Population, Density, and Network Effects
This paper builds on the optimal city size literature by examining factors that influence location benefits and costs. Total population, population density, employment type, and networking are evaluated using ordinary least squares. Results indicate that population density may play a more significant role in predicting average location benefits and average location costs than population. 
Development of a parametric analysis microcomputer model for evaluating the thermodynamic performance of a reciprocating Brayton cycle engine
In this thesis, applicable data from research on IC engines have been adapted to PACE engine designs. Data from studies on heat transfer, friction, and pressure losses, in particular, have been used. Certain parameters which define operation and design characteristics appear to influence PACE engine performance very strongly. Some of the more critical parameters, notably friction and heat transfer coefficients, must be determined experimentally if accurate model results are to be expected. Pressure ratio, compressor RPM, and maximum combustor temperature, the independent operating parameters, also have a dramatic effect on engine performance. Other design or operating characteristics and working fluid properties are not controlled independently. These are dictated by the engine physical design configuration and operation, ambient conditions, and choice of fuel
CI emission in Ultra Luminous Infrared Galaxies as a molecular gas mass tracer
We present new sensitive wide-band measurements of the fine structure line
3^P_1 -> 3^P_0 (J=1-0, 492GHz) of neutral atomic carbon (CI) in the two typical
Ultra Luminous Infrared Galaxies NGC6240 and Arp220. We then use them along
with several other CI measurements in similar objects found in the literature
to estimate their global molecular gas content under the assumption of a full
CI-H_2 concomitance. We find excellent agreement between the H_2 gas mass
estimated with this method and the standard methods using 12^CO. This may
provide a new way to measure H_2 gas mass in galaxies, and one which may be
very valuable in ULIRGs since in such systems the bright 12^CO emission is
known to systematically overestimate the gas mass while their 13^CO emission is
usually very weak. At redshifts z>=1 the CI J=1-0 line shifts to much more
favorable atmospheric windows and can become a viable alternative tracer of the
H_2 gas fueling starburst events in the distant Universe.Comment: 11 pages, 2 figures. Accepted for publication in ApJ Letter
A DSMC investigation of gas flows in micro-channels with bends
Pressure-driven, implicit boundary conditions are implemented in an open source direct simulation Monte Carlo (DSMC) solver, and benchmarked against simple micro-channel flow cases found in the literature. DSMC simulations are then carried out of gas flows for varying degrees of rarefaction along micro-channels with both one and two ninety-degree bends. The results are compared to those from the equivalent straight micro-channel geometry. Away from the immediate bend regions, the pressure and Mach number profiles do not differ greatly from those in straight channels, indicating that there are no significant losses introduced when a bend is added to a micro-channel geometry. It is found that the inclusion of a bend in a micro-channel can increase the amount of mass that a channel can carry, and that adding a second bend produces a greater mass flux enhancement. This increase happens within a small range of Knudsen number (0.02 Knin 0.08). Velocity slip and shear stress profiles at the channel walls are presented for the Knudsen showing the largest mass flux enhancement
Increasing Spectrum for Broadband: What Are The Options?
The growth of wireless broadband is a bright spot in the U.S. economy, but a shortage of flexibly licensed spectrum rights could put a crimp on this expansion. Freeing up spectrum from other uses would allow greater expansion of wireless broadband and would bring substantial gains—likely in the hundreds of billions of dollars—for U.S. consumers, businesses, and the federal treasury. ... U.S. experience suggests that it takes at least six years, and possibly over a decade, to complete any large-scale reallocation of spectrum. Thus, for policymakers, the ?projected? need is actually here today. This paper makes three proposals to increase spectrum available for wireless broadband under a flexibly licensed, market-based regime.
Reliability-Based Design of Thermal Protection Systems with Support Vector Machines
The primary objective of this work was to develop a computationally efficient and accurate approach to reliability analysis of thermal protection systems using support vector machines. An adaptive sampling approach was introduced informs a iterative support vector machine approximation of the limit state function used for measuring reliability. The proposed sampling approach efficient adds samples along the limit state function until the reliability approximation is converged. This methodology is applied to two samples, mathematical functions to test and demonstrate the applicability. Then, the adaptive sampling-based support vector machine approach is applied to the reliability analysis of a thermal protection system. The results of all three problems highlight the potential capability of the new approach in terms of accuracy and computational saving in determining thermal protection system reliability
Calibration Probe Uncertainty and Validation for the Hypersonic Material Environmental Test System
This paper presents an uncertainty analysis of the stagnation-point calibration probe surface predictions for conditions that span the performance envelope of the Hypersonic Materials Environmental Test System facility located at NASA Langley Research Center. A second-order stochastic expansion was constructed over 47 uncertain parameters to evaluate the sensitivities, identify the most significant uncertain variables, and quantify the uncertainty in the stagnation-point heat flux and pressure predictions of the calibration probe for a low- and high-enthalpy test condition. A sensitivity analysis showed that measurement bias uncertainty is the most significant contributor to the stagnation-point pressure and heat flux variance for the low-enthalpy condition. For the high-enthalpy condition, a paradigm shift in sensitivities revealed the computational fluid dynamics model input uncertainty as the main contributor. A comparison between the prediction and measurement of the stagnation-point conditions under uncertainty showed that there was evidence of statistical disagreement. A validation metric was proposed and applied to the prediction uncertainty to account for the statistical disagreement when compared to the possible stagnation-point heat flux and pressure measurements
Mechanisms of Bacterial Extracellular Electron Exchange.
The biochemical mechanisms by which microbes interact with extracellular soluble metal ions and insoluble redox-active minerals have been the focus of intense research over the last three decades. The process presents two challenges to the microorganism; firstly electrons have to be transported at the cell surface, which in Gram negative bacteria presents an additional problem of electron transfer across the ~ 6 nm of the outer membrane. Secondly the electrons must be transferred to or from the terminal electron acceptors or donors. This review covers the known mechanisms that bacteria use to transport electrons across the cell envelope to external electron donors/acceptors. In Gram negative bacteria electron transfer across the outer membrane involves the use of an outer membrane β-barrel and cytochrome. These can be in the form of a porin-cytochrome protein, such as Cyc2 of Acidothiobacillus ferrioxydans, or a multiprotein porin-cytochrome complex like MtrCAB of Shewanella oneidensis MR-1. For mineral respiring organisms there is the additional challenge of transferring the electrons from the cell to mineral surface. For the strict anaerobe Geobacter sulfurreducens this requires electron transfer through conductive pili to associated cytochrome OmcS that directly reduces Fe(III)oxides, while the facultative anaerobe S. oneidensis MR-1 accomplishes mineral reduction through direct membrane contact, contact through filamentous extentions and soluble flavin shuttles, all of which require the outer membrane cytochromes MtrC and OmcA in addition to secreted flavin
Thinking territory historically.
BACKGROUND:
While the randomised controlled trial (RCT) is generally regarded as the design of
choice for assessing the effects of health care, within the social sciences there is
considerable debate about the relative suitability of RCTs and non-randomised
studies (NRSs) for evaluating public policy interventions.
// OBJECTIVES:
To determine whether RCTs lead to the same effect size and variance as NRSs of
similar policy interventions; and whether these findings can be explained by other
factors associated with the interventions or their evaluation.
// METHODS:
Analyses of methodological studies, empirical reviews, and individual health and
social services studies investigated the relationship between randomisation and
effect size of policy interventions by:
1) Comparing controlled trials that are identical in all respects other than the use of
randomisation by 'breaking' the randomisation in a trial to create non-randomised
trials (re-sampling studies).
2) Comparing randomised and non-randomised arms of controlled trials mounted
simultaneously in the field (replication studies).
3) Comparing similar controlled trials drawn from systematic reviews that include
both randomised and non-randomised studies (structured narrative reviews and
sensitivity analyses within meta-analyses).
4) Investigating associations between randomisation and effect size using a pool of
more diverse RCTs and NRSs within broadly similar areas (meta-epidemiology).
// RESULTS:
Prior methodological reviews and meta-analyses of existing reviews comparing
effects from RCTs and nRCTs suggested that effect sizes from RCTs and nRCTs
may indeed differ in some circumstances and that these differences may well be
associated with factors confounded with design.
Re-sampling studies offer no evidence that the absence of randomisation directly
influences the effect size of policy interventions in a systematic way. No consistent
explanations were found for randomisation being associated with changes in effect
sizes of policy interventions in field trials
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