938 research outputs found

    Sustainability Planning as Paradigm Change

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    The theme of the next issue of Urban Planning will be Paradigm Shifts. To make the link between “sustainability” and “paradigm change,” the following commentary analyzes the former concept as a main example of the latter. Although it is often applied to rather modest planning initiatives, “sustainability” can be seen as requiring shifts in cognitive paradigm that are transformational, radical, and not yet fully appreciated by most of those who use the term. Specifically, this term implies a proactive, results-oriented approach (e.g. initiatives to actually meet GHG reduction targets), a long-term viewpoint (e.g. planning for 50 or 100+ years in the future), and a holistic or ecological mindset able to understand dynamic, evolving systems. This last change is the most difficult and requires thinking across scales of action, across time frames, across issue areas and goals (e.g. the “Three E’s” of environment, economy, and social equity), and across communities. It also means integrating different types of actions into a broader program of social change. Though challenging, these cognitive shifts can lead to radically different outcomes than past urban planning

    Accessus ad auctores: Medieval Introductions to the Authors (Codex latinus monacensis 19475)

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    Medieval commentaries typically included an accessus, a standardized introduction to an author or book. In the twelfth century these introductions were anthologised, referred to now as Accessus ad auctores. They served as the first handbooks of literary criticism. The earliest and most comprehensive example, Bayerische Staatsbibliothek, Clm 19475, saec. XII, is presented here for the first time in a faithful critical edition, with a new translation and explanatory notes addressing different aspects of the text. This book\u27s aim is to present an accurate version of the text while respecting the arrangement and integrity of the anthology as a whole, and includes previously unpublished material from the anthology.https://scholarworks.wmich.edu/mip_teamssc/1002/thumbnail.jp

    A Carbon-Neutral California: Social Ecology and Prospects for 2050 GHG Reduction

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    How might a large jurisdiction approach carbon neutrality by 2050, and what initiatives might increase the chances of success? This article explores these questions using California as a case study. Current trends as well as multiple modeling studies show that existing policy directions for the state will not be sufficient. Additional initiatives appear needed to accelerate adoption of electric vehicles, reduce driving, reach 100 percent renewable electricity, convert existing buildings to zero-net-carbon status, change diet, and reduce consumption. The state’s social ecology does not currently support such changes. Consequently, planners and other professionals need to consider strategic actions to change social ecology as well as climate policy. Potential steps to do this include raising the price of carbon; revising the state’s tax system so as to increase public sector capacity; developing a stronger framework of incentives, mandates, and technical support between levels of government; and expanding educational and social marketing programs aimed at behavior change. A main implication of this analysis is that in many contexts worldwide sustainability planners should consider action on both policy and social ecology levels to maximize chances of success

    A Carbon-Neutral California: Social Ecology and Prospects for 2050 GHG Reduction

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    How might a large jurisdiction approach carbon neutrality by 2050, and what initiatives might increase the chances of success? This article explores these questions using California as a case study. Current trends as well as multiple modeling studies show that existing policy directions for the state will not be sufficient. Additional initiatives appear needed to accelerate adoption of electric vehicles, reduce driving, reach 100 percent renewable electricity, convert existing buildings to zero-net-carbon status, change diet, and reduce consumption. The state’s social ecology does not currently support such changes. Consequently, planners and other professionals need to consider strategic actions to change social ecology as well as climate policy. Potential steps to do this include raising the price of carbon; revising the state’s tax system so as to increase public sector capacity; developing a stronger framework of incentives, mandates, and technical support between levels of government; and expanding educational and social marketing programs aimed at behavior change. A main implication of this analysis is that in many contexts worldwide sustainability planners should consider action on both policy and social ecology levels to maximize chances of success

    Cerebrospinal fluid levels of extracellular heat shock protein 72: A potential biomarker for bacterial meningitis in children

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    Extracellular heat shock protein 72 (Hsp72) is an endogenous danger signal and potential biomarker for critical illness in children. We hypothesized that elevated levels of extracellular Hsp72 in the cerebrospinal fluid (CSF) of children with suspected meningitis could predict bacterial meningitis. We measured extracellular Hsp72 levels in the CSF of 31 critically ill children with suspected meningitis via a commercially available enzyme-linked immunosorbent assay. Fourteen had bacterial meningitis based on CSF pleocytosis and bacterial growth in either blood or CSF culture. Seventeen children with negative cultures comprised the control group. CSF Hsp72 was significantly elevated in children with bacterial meningitis compared to controls. Importantly, CSF Hsp72 levels did not correlate with the CSF white blood cell count. On receiver operator characteristic analysis, using a cut-off of 8.1 ng/mL, CSF Hsp72 has a sensitivity of 79% and a specificity of 94% for predicting bacterial meningitis. We therefore conclude that CSF extracellular Hsp72 levels are elevated in critically ill children with bacterial meningitis versus controls. Hsp72 potentially offers clinicians improved diagnostic information in distinguishing bacterial meningitis from other processes

    Gold Country: the politics of landscape in exurban El Dorado County, California

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    Low-density exurban landscapes threaten ecosystems and pose challenges for urban and regional planning, especially in nations with relatively weak rural land use regulation like the United States. Growth management efforts in such areas have generally been difficult due to strong pro-development forces and cultures of landowner rights. This article explores the political ecology of planning in one such exurban place, El Dorado County in the Sierra Nevada foothills east of Sacramento, California. Through review of historical documents, news articles, over a dozen interviews with knowledgeable local actors, and GIS analysis of growth patterns, we discuss how a demobilization of local planning develops through dynamics of power, fear, distrust, and antagonism. We explore some possible strategies for developing stronger local planning mechanisms, including more collaborative planning, better articulation of alternative growth models, and strengthened state and regional planning frameworks. Keywords: Exurbia, political ecology, urban planning, landscape, cultural geography, California

    Heitt Mjölnir: a heated miniature triaxial apparatus for 4D synchrotron microtomography

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    Third- and fourth-generation synchrotron light sources with high fluxes and beam energies enable the use of innovative X-ray translucent experimental apparatus. These experimental devices access geologically relevant conditions whilst enabling in situ characterization using the spatial and temporal resolutions accessible at imaging beamlines. Here, Heitt Mjölnir is introduced, a heated miniature triaxial rig based on the design of Mjölnir, but covering a wider temperature range and larger sample volume at similar pressure capacities. This device is designed to investigate coupled thermal, chemical, hydraulic and mechanical processes from grain to centimetre scales using cylindrical samples of 10 mm × 20 mm (diameter × length). Heitt Mjölnir can simultaneously reach confining (hydraulic) pressures of 30 MPa and 500 MPa of axial stress with independently controlled sample pore fluid pressure < 30 MPa. This internally heated apparatus operates to temperatures up to 573 K with a minimal vertical thermal gradient in the sample of <0.3 K mm−1. This new apparatus has been deployed in operando studies at the TOMCAT (Swiss Light Source), I12 JEEP (Diamond Light Source) and PSICHÉ (Synchrotron SOLEIL) beamlines for 4D X-ray microtomography with scan intervals of a few minutes. Heitt Mjölnir is portable and modular, allowing a wide range of 4D characterizations of low-grade metamorphism and deformational processes. It enables spatially and temporally resolved fluid–rock interaction studies at conditions of crustal reservoirs and is suitable for characterization of material properties in geothermal, carbonation or subsurface gas storage applications. Technical drawings and an operation guide are included in this publication

    Observations of SN 2017ein Reveal Shock Breakout Emission and A Massive Progenitor Star for a Type Ic Supernova

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    We present optical and ultraviolet observations of nearby type Ic supernova SN 2017ein as well as detailed analysis of its progenitor properties from both the early-time observations and the prediscovery Hubble Space Telescope (HST) images. The optical light curves started from within one day to \sim275 days after explosion, and optical spectra range from \sim2 days to \sim90 days after explosion. Compared to other normal SNe Ic like SN 2007gr and SN 2013ge, \mbox{SN 2017ein} seems to have more prominent C{\footnotesize II} absorption and higher expansion velocities in early phases, suggestive of relatively lower ejecta mass. The earliest photometry obtained for \mbox{SN 2017ein} show indications of shock cooling. The best-fit obtained by including a shock cooling component gives an estimate of the envelope mass as \sim0.02 M_{\odot} and stellar radius as 8±\pm4 R_{\odot}. Examining the pre-explosion images taken with the HST WFPC2, we find that the SN position coincides with a luminous and blue point-like source, with an extinction-corrected absolute magnitude of MV_V\sim-8.2 mag and MI_I\sim-7.7 mag.Comparisons of the observations to the theoretical models indicate that the counterpart source was either a single WR star or a binary with whose members had high initial masses, or a young compact star cluster. To further distinguish between different scenarios requires revisiting the site of the progenitor with HST after the SN fades away.Comment: 28 pages, 19 figures; accepted for publication in The Astrophysical Journa

    Common single nucleotide polymorphisms in genes related to immune function and risk of papillary thyroid cancer

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    Accumulating evidence suggests that alterations in immune function may be important in the etiology of papillary thyroid cancer (PTC). To identify genetic markers in immune-related pathways, we evaluated 3,985 tag single nucleotide polymorphisms (SNPs) in 230 candidate gene regions (adhesion-extravasation-migration, arachidonic acid metabolism/eicosanoid signaling, complement and coagulation cascade, cytokine signaling, innate pathogen detection and antimicrobials, leukocyte signaling, TNF/NF-kB pathway or other) in a case-control study of 344 PTC cases and 452 controls. We used logistic regression models to estimate odds ratios (OR) and calculate one degree of freedom P values of linear trend (P(SNP-trend)) for the association between genotype (common homozygous, heterozygous, variant homozygous) and risk of PTC. To correct for multiple comparisons, we applied the false discovery rate method (FDR). Gene region- and pathway-level associations (P(Region) and P(Pathway)) were assessed by combining individual P(SNP-trend) values using the adaptive rank truncated product method. Two SNPs (rs6115, rs6112) in the SERPINA5 gene were significantly associated with risk of PTC (P(SNP-FDR)/P(SNP-trend) = 0.02/6×10(−6) and P(SNP-FDR)/P(SNP-trend) = 0.04/2×10(−5), respectively). These associations were independent of a history of autoimmune thyroiditis (OR = 6.4; 95% confidence interval: 3.0–13.4). At the gene region level, SERPINA5 was suggestively associated with risk of PTC (P(Region-FDR)/P(Region = )0.07/0.0003). Overall, the complement and coagulation cascade pathway was the most significant pathway (P(Pathway) = 0.02) associated with PTC risk largely due to the strong effect of SERPINA5. Our results require replication but suggest that the SERPINA5 gene, which codes for the protein C inhibitor involved in many biological processes including inflammation, may be a new susceptibility locus for PTC

    Agricultural mitigation and adaptation to climate change in Yolo County, CA

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    This place‐based case study in an agricultural county in California’s Central Valley focused on the period of 2010–2050, and dealt with biophysical and socioeconomic issues related to both mitigation of greenhouse gas (GHG) emissions and to adaptation to an uncertain climate. In the past 100 years, changes in crop acreage has been more related to crop price and availability of irrigation water than to growing degree days during summer, and in fact, summer temperatures have increased less than winter temperatures. Econometric analysis indicated that warmer winters, as projected by Geophysical Fluid Dynamics Laboratory‐Bias Corrected Constructed Analog during 2035–2050, could result in less wheat acreage, more alfalfa and tomato acreage, and slight effects on tree and vine crops. The Water Evaluation and Planning (WEAP) model showed that these econometric projections did not reduce irrigation demand under either the B1 or A2 scenarios, but a diverse, water‐efficient cropping pattern combined with improved irrigation technology reduced demand to 12 percent below the historic mean. Collaboration during development of Yolo County’s Climate Action Plan showed that nitrous oxide (mainly from nitrogen fertilizers) was the main source (≅40 percent) of agricultural emissions. Emissions from cropland and rangeland were several orders of magnitude lower than urbanized land per unit area. A survey distributed to 570 farmers and ranchers achieved a 34 percent response rate. Farmers concerned about climate change were more likely to implement water conservation practices, and adopt voluntary GHG mitigation practices. Use of the urban growth model (UPlan) showed that channeling much or all future urban development into existing urban areas will increase ecosystem services by preserving agricultural land and open space, immensely reducing the Yolo County’s GHG emissions, and greatly enhancing agricultural sustainability
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