106 research outputs found
Video Laparoscopic Cholecystectomy : the last diagnostic step or the first Surgical procedure to prevent Cancer? A review of incidental Galbladder Cancer
Letter graphs and geometric grid classes of permutations: Characterization and recognition.
In this paper, we reveal an intriguing relationship between two seemingly unrelated notions: letter graphs and geometric grid classes of permutations. An important property common for both of them is well-quasi-orderability, implying, in a non-constructive way, a polynomial-time recognition of geometric grid classes of permutations and -letter graphs for a fixed . However, explicit algorithms are available only for . In this paper, we present the first explicit polynomial-time algorithm for the recognition of 3-letter graphs over a cyclic decoder. It is based on a structural characterization of graphs in this clas
Diagnostic accuracy of procalcitonin in critically ill immunocompromised patients
<p>Abstract</p> <p>Background</p> <p>Recognizing infection is crucial in immunocompromised patients with organ dysfunction. Our objective was to assess the diagnostic accuracy of procalcitonin (PCT) in critically ill immunocompromised patients.</p> <p>Methods</p> <p>This prospective, observational study included patients with suspected sepsis. Patients were classified into one of three diagnostic groups: no infection, bacterial sepsis, and nonbacterial sepsis.</p> <p>Results</p> <p>We included 119 patients with a median age of 54 years (interquartile range [IQR], 42-68 years). The general severity (SAPSII) and organ dysfunction (LOD) scores on day 1 were 45 (35-62.7) and 4 (2-6), respectively, and overall hospital mortality was 32.8%. Causes of immunodepression were hematological disorders (64 patients, 53.8%), HIV infection (31 patients, 26%), and solid cancers (26 patients, 21.8%). Bacterial sepsis was diagnosed in 58 patients and nonbacterial infections in nine patients (7.6%); 52 patients (43.7%) had no infection. PCT concentrations on the first ICU day were higher in the group with bacterial sepsis (4.42 [1.60-22.14] vs. 0.26 [0.09-1.26] ng/ml in patients without bacterial infection, <it>P </it>< 0.0001). PCT concentrations on day 1 that were > 0.5 ng/ml had 100% sensitivity but only 63% specificity for diagnosing bacterial sepsis. The area under the receiver operating characteristic (ROC) curve was 0.851 (0.78-0.92). In multivariate analyses, PCT concentrations > 0.5 ng/ml on day 1 independently predicted bacterial sepsis (odds ratio, 8.6; 95% confidence interval, 2.53-29.3; <it>P </it>= 0.0006). PCT concentrations were not significantly correlated with hospital mortality.</p> <p>Conclusion</p> <p>Despite limited specificity in critically ill immunocompromised patients, PCT concentrations may help to rule out bacterial infection.</p
On a Clique-Based Integer Programming Formulation of Vertex Colouring with Applications in Course Timetabling
Vertex colouring is a well-known problem in combinatorial optimisation, whose
alternative integer programming formulations have recently attracted
considerable attention. This paper briefly surveys seven known formulations of
vertex colouring and introduces a formulation of vertex colouring using a
suitable clique partition of the graph. This formulation is applicable in
timetabling applications, where such a clique partition of the conflict graph
is given implicitly. In contrast with some alternatives, the presented
formulation can also be easily extended to accommodate complex performance
indicators (``soft constraints'') imposed in a number of real-life course
timetabling applications. Its performance depends on the quality of the clique
partition, but encouraging empirical results for the Udine Course Timetabling
problem are reported
The effect of temperature on the phenotypic features and the maceration ability of Dickeya solani strains isolated in Finland, Israel and Poland
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