105 research outputs found

    Long-term monitoring of geodynamic surface deformation using SAR interferometry

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    Thesis (Ph.D.) University of Alaska Fairbanks, 2014Synthetic Aperture Radar Interferometry (InSAR) is a powerful tool to measure surface deformation and is well suited for surveying active volcanoes using historical and existing satellites. However, the value and applicability of InSAR for geodynamic monitoring problems is limited by the influence of temporal decorrelation and electromagnetic path delay variations in the atmosphere, both of which reduce the sensitivity and accuracy of the technique. The aim of this PhD thesis research is: how to optimize the quantity and quality of deformation signals extracted from InSAR stacks that contain only a low number of images in order to facilitate volcano monitoring and the study of their geophysical signatures. In particular, the focus is on methods of mitigating atmospheric artifacts in interferograms by combining time-series InSAR techniques and external atmospheric delay maps derived by Numerical Weather Prediction (NWP) models. In the first chapter of the thesis, the potential of the NWP Weather Research & Forecasting (WRF) model for InSAR data correction has been studied extensively. Forecasted atmospheric delays derived from operational High Resolution Rapid Refresh for the Alaska region (HRRRAK) products have been compared to radiosonding measurements in the first chapter. The result suggests that the HRRR-AK operational products are a good data source for correcting atmospheric delays in spaceborne geodetic radar observations, if the geophysical signal to be observed is larger than 20 mm. In the second chapter, an advanced method for integrating NWP products into the time series InSAR workflow is developed. The efficiency of the algorithm is tested via simulated data experiments, which demonstrate the method outperforms other more conventional methods. In Chapter 3, a geophysical case study is performed by applying the developed algorithm to the active volcanoes of Unimak Island Alaska (Westdahl, Fisher and Shishaldin) for long term volcano deformation monitoring. The volcano source location at Westdahl is determined to be approx. 7 km below sea level and approx. 3.5 km north of the Westdahl peak. This study demonstrates that Fisher caldera has had continuous subsidence over more than 10 years and there is no evident deformation signal around Shishaldin peak.Chapter 1. Performance of the High Resolution Atmospheric Model HRRR-AK for Correcting Geodetic Observations from Spaceborne Radars -- Chapter 2. Robust atmospheric filtering of InSAR data based on numerical weather prediction models -- Chapter 3. Subtle motion long term monitoring of Unimak Island from 2003 to 2010 by advanced time series SAR interferometry -- Chapter 4. Conclusion and future work

    Fault slip of the 2022 Mw6.7 Menyuan, China earthquake observed by InSAR, and its tectonic implications

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    In this article the ascending and descending Sentinel-1A satellite data are used to investigate the coseismic slip model of the 2022 Mw6.7 Menyuan earthquake in Qinghai, China. The optimal slip model indicates that this event ruptured two fault segments. The main rupture concentrated on the western Lenglongling fault (LLLF) with a purely left-lateral striking-slip motion. A small part of the eastern Tuolaishan fault (TLSF) section was also ruptured, and the motion on it is mainly oblique slip at depth, with an obvious thrust component. Combined with the rupture characteristics of historical events, GPS velocity map, and slip rate studies, we suggest that the TLSF–LLLF junction is a demarcation point where the deformation partitioning pattern has changed. Along the whole LLLF segment, the oblique convergence has completely partitioned into slip on the purely strike-slipping LLLF and thrusting faults in the north. The TLSF segment accommodates a fraction of compressional shortening, which compensates for the discrepancy in the left-lateral slip rate between the LLLF and TLSF. Such transformation in the strain partitioning pattern is likely to be determined by the geometric relationship between the fault strike and the direction of regional block movement

    ACQ: Improving Generative Data-free Quantization Via Attention Correction

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    Data-free quantization aims to achieve model quantization without accessing any authentic sample. It is significant in an application-oriented context involving data privacy. Converting noise vectors into synthetic samples through a generator is a popular data-free quantization method, which is called generative data-free quantization. However, there is a difference in attention between synthetic samples and authentic samples. This is always ignored and restricts the quantization performance. First, since synthetic samples of the same class are prone to have homogenous attention, the quantized network can only learn limited modes of attention. Second, synthetic samples in eval mode and training mode exhibit different attention. Hence, the batch-normalization statistics matching tends to be inaccurate. ACQ is proposed in this paper to fix the attention of synthetic samples. An attention center position-condition generator is established regarding the homogenization of intra-class attention. Restricted by the attention center matching loss, the attention center position is treated as the generator's condition input to guide synthetic samples in obtaining diverse attention. Moreover, we design adversarial loss of paired synthetic samples under the same condition to prevent the generator from paying overmuch attention to the condition, which may result in mode collapse. To improve the attention similarity of synthetic samples in different network modes, we introduce a consistency penalty to guarantee accurate BN statistics matching. The experimental results demonstrate that ACQ effectively improves the attention problems of synthetic samples. Under various training settings, ACQ achieves the best quantization performance. For the 4-bit quantization of Resnet18 and Resnet50, ACQ reaches 67.55% and 72.23% accuracy, respectively

    A Fine Velocity and Strain Rate Field of Present-Day Crustal Motion of the Northeastern Tibetan Plateau Inverted Jointly by InSAR and GPS

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    Interferometric synthetic aperture radar (InSAR) data from 6 Envisat ASAR descending tracks; spanning the 2003⁻2010 period; was used to measure interseismic strain accumulation across the Northeastern Tibetan Plateau. Mean line-of-sight (LOS) ratemaps are computed by stacking atmospheric-corrected and orbital-corrected interferograms. The ratemaps from one track with different atmospheric-corrected results or two parallel; partially overlapping tracks; show a consistent pattern of left-lateral motion across the fault; which demonstrates the MERIS and ECMWF atmospheric correction works satisfactorily for small stain measurement of this region; even with a limited number of interferograms. By combining the measurements of InSAR and GPS; a fine crustal deformation velocity and strain rate field was estimated on discrete points with irregular density depending on the fault location; which revealed that the present-day slip rate on the Haiyuan fault system varies little from west to east. A change (2⁻3 mm/year) in line-of-sight (LOS) deformation rate across the fault is observed from the Jinqianghe segment to its eastern end. Inversion from the cross-fault InSAR profiles gave a shallow locking depth of 3⁻6 km on the main rupture of the 1920 earthquake. We therefore infer that the middle-lower part of the seismogenic layer on the 1920 rupture is not yet fully locked since the 1920 large earthquake. Benefit from high spatial resolution InSAR data; a low strain accumulation zone with high strain rates on its two ends was detected; which corresponds to the creeping segment; i.e., the Laohushan fault segment. Contrary to the previous knowledge of squeezing structure; an abnormal tension zone is disclosed from the direction map of principal stress; which is consistent with the recent geological study. The distribution of principal stress also showed that the expanding frontier of the northeastern plateau has crossed the Liupan Shan fault zone; even arrived at the northeast area of the Xiaoguan Shan. This result agrees with the deep seismic reflection profile

    PO-209 Effects of aerobic exercise on oxidant/anti-oxidant indexes and gut microbiota in young obese volunteers

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      Objective The mean body mass index (BMI) and the prevalence of obese and overweight individuals increasing substantially worldwide during the previous three decades. Variation in gut microorganisms might play an important role in the pathogenesis of obesity, but the mechanisms by which gut microbiota promote metabolic disturbances are not well understood. Exercise is associated with altered gut microbial composition, but few studies have investigated whether the gut microbiota and associated metabolites are modulated by exercise training in humans. We explored the impact of 8 weeks aerobic exercise on serum oxidant and anti-oxidant indexes and gut microbiota. Methods All 40 young male volunteers are enrolled in the study, the lean ones (n=11), which BMI≤22 are as control group. And the obese ones (n=29), which BMI > 28 participated in the 8 weeks aerobic exercise. The body weight and BMI of each volunteers were recorded. The serum malondialdehyde (MDA), superoxide dismutase (SOD), glutathione peroxidase (GPx) and total antioxidant capacity (TAOC) were measured by ELISA. The composition and diversity of gut microbiota were analyzed with 16S rDNA sequencing. Results ① Compared with the control, the level of serum GPx, SOD and TAOC decreased significantly (P < 0.001), and the MDA increased significantly (P < 0.001) in the obese group. After the 8 weeks aerobic exercise intervention, the MDA level decreased significantly (P<0.01), the TAOC level increased significantly (P < 0.01), and there were no significant changes in the level of GPX and SOD. ② Compared with the control, the ratio of Bifidobacteriaceae, Alcaligenaceae, Erysipelotrichaceae, and Verrucomicrobiaceae decreased significantly(p<0.05) in the obese group, and the ratio of Ruminococcaceae, Helicobacteraceae increased significantly (P<0.05). After the 8 weeks aerobic exercise intervention, the ratio of Bifidobacteriaceae, Alcaligenaceae increased significantly (P<0.05),and the ratio of Ruminococcaceae reduced remarkably (p<0.05). The ACE index was significantly increased after the intervention (P < 0.05). ③ Through the correlation analysis of the data above, there was a certain correlation between the serum oxidant/anti-oxidant indexes and gut microbiota composition. After the aerobic exercise, there was a positive correlation between MDA and Ruminococcaceae、TAOC and Bifdobacteriace (P<0.05);a negative correlation between MDA and Bifdobacteriace、TAOC and Ruminococcaceae (P<0.05). After 8 weeks of aerobic exercise, MDA level was negatively correlated with ACE index (r=-0.466,P<0.05). Conclusions ① Compared with the control, there was a significant increase of serum oxidation index and the serum anti-oxidation index dropped significantly among the obese subjects, which indicated that the accumulation of serum free radicals might be one of the causes of obesity. The 8 weeks aerobic exercise intervention can enhance the antioxidant capacity effectively. ② Compared with the control, the proportion of Bifidobacteriaceae in the obese group was significantly decreased, and the proportion of the bacteria with direct correlation to obesity, such as Ruminococcaceae increased significantly. 8 weeks aerobic exercise could inverse these changes among the obese subjects, suggested that the improvement of body phenotype of obese subjects was closely related to the effective regulation of their gut microbiota structure.The change of ACE index indicated that aerobic exercise could increase the diversity of gut microbiota. ③ Combined the correlation analysis of gut microbiota diversity index showed that there were tight correlation between the serum oxidant/anti-oxidant indexes and the gut microbiota composition and structure. It might caused metabolic disorders and eventually increased fat accumulation and changed the host body phenotype.     &nbsp

    Comparison of small baseline interferometric SAR processors for estimating ground deformation

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    The small Baseline Synthetic Aperture Radar (SAR) Interferometry (SBI) technique has been widely and successfully applied in various ground deformation monitoring applications. Over the last decade, a variety of SBI algorithms have been developed based on the same fundamental concepts. Recently developed SBI toolboxes provide an open environment for researchers to apply different SBI methods for various purposes. However, there has been no thorough discussion that compares the particular characteristics of different SBI methods and their corresponding performance in ground deformation reconstruction. Thus, two SBI toolboxes that implement a total of four SBI algorithms were selected for comparison. This study discusses and summarizes the main differences, pros and cons of these four SBI implementations, which could help users to choose a suitable SBI method for their specific application. The study focuses on exploring the suitability of each SBI module under various data set conditions, including small/large number of interferograms, the presence or absence of larger time gaps, urban/vegetation ground coverage, and temporally regular/irregular ground displacement with multiple spatial scales. Within this paper we discuss the corresponding theoretical background of each SBI method. We present a performance analysis of these SBI modules based on two real data sets characterized by different environmental and surface deformation conditions. The study shows that all four SBI processors are capable of generating similar ground deformation results when the data set has sufficient temporal sampling and a stable ground backscatter mechanism like urban area. Strengths and limitations of different SBI processors were analyzed based on data set configuration and environmental conditions and are summarized in this paper to guide future users of SBI techniques

    The 5th International Conference on Biomedical Engineering and Biotechnology (ICBEB 2016)

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    Hypoxic TAM-derived exosomal miR-155-5p promotes RCC progression through HuR-dependent IGF1R/AKT/PI3K pathway

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    Abstract Hypoxic tumor-associated macrophages (TAMs) are related to poor prognosis of patients with clear cell renal cell carcinoma (ccRCC). Exosomes are small lipid-bilayer vesicles that implicated in tumor progression and metastasis. However, whether hypoxic TAM-derived exosomes affect RCC progression within the hypoxic tumor microenvironment has not been elucidated. GSE analysis identified miR-155-5p was upregulated in RCC. Moreover, we quantified levels of miR-155-5p using RT-qPCR, performed immunohistochemical staining in 79 pairs of primary RCC specimens and related them to clinicopathological parameters. Higher miR-155-5p levels were related to more CD163 + TAM infiltration and elevated HIF-1a expression in our cohort. In the in vitro studies, we initially purified and characterized the exosomes from the supernatant of TAMs subjected to normoxia or hypoxia, and then transfected antagomiR-155-5p or control into these TAMs to produce corresponding exosomes. Gain and loss-of-function studies further investigated the effect of transferred hypoxic exosomal miR-155-5p on the cross-talk between TAMs and RCC cells in xenograft model and in vitro co-culture experiments. The results of RNA immunoprecipitation analyses elucidated that miR-155-5p could directly interact with human antigen R (HuR), thus increasing IGF1R mRNA stability. Mechanistically, hypoxic TAM-Exo transferred miR-155-5p promoted RCC progression partially through activating IGF1R/PI3K/AKT cascades. Taken together, transfer of miR-155-5p from hypoxic TAMs by exosomes to renal cancer cells explains the oncogenic manner, in which M2 macrophages confer the malignant phenotype to RCC cells by enhancing HuR-mediated mRNA stability of IGF1R
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