12 research outputs found

    Influence and Optimization of Packet Loss on the Internet-Based Geographically Distributed Test Platform for Fuel Cell Electric Vehicle Powertrain Systems

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    In view of recent developments in fuel cell electric vehicle powertrain systems, Internet-based geographically distributed test platforms for fuel cell electric vehicle powertrain systems become a development and validation trend. Due to the involvement of remote connection and the Internet, simulation with connected models can suffer great uncertainty because of packet loss. Such a test platform, including packet loss characteristics, was built using MATLAB/Simulink for use in this paper. The simulation analysis results show that packet loss affects the stability of the whole test system. The impact on vehicle speed is mainly concentrated in the later stage of simulation. Aiming at reducing the effect of packet loss caused by Internet, a robust model predictive compensator was designed. Under this compensator, the stability of the system is greatly improved compared to the system without a compensator

    Partial Order Optimum Likelihood (POOL): Maximum Likelihood Prediction of Protein Active Site Residues Using 3D Structure and Sequence Properties

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    A new monotonicity-constrained maximum likelihood approach, called Partial Order Optimum Likelihood (POOL), is presented and applied to the problem of functional site prediction in protein 3D structures, an important current challenge in genomics. The input consists of electrostatic and geometric properties derived from the 3D structure of the query protein alone. Sequence-based conservation information, where available, may also be incorporated. Electrostatics features from THEMATICS are combined with multidimensional isotonic regression to form maximum likelihood estimates of probabilities that specific residues belong to an active site. This allows likelihood ranking of all ionizable residues in a given protein based on THEMATICS features. The corresponding ROC curves and statistical significance tests demonstrate that this method outperforms prior THEMATICS-based methods, which in turn have been shown previously to outperform other 3D-structure-based methods for identifying active site residues. Then it is shown that the addition of one simple geometric property, the size rank of the cleft in which a given residue is contained, yields improved performance. Extension of the method to include predictions of non-ionizable residues is achieved through the introduction of environment variables. This extension results in even better performance than THEMATICS alone and constitutes to date the best functional site predictor based on 3D structure only, achieving nearly the same level of performance as methods that use both 3D structure and sequence alignment data. Finally, the method also easily incorporates such sequence alignment data, and when this information is included, the resulting method is shown to outperform the best current methods using any combination of sequence alignments and 3D structures. Included is an analysis demonstrating that when THEMATICS features, cleft size rank, and alignment-based conservation scores are used individually or in combination THEMATICS features represent the single most important component of such classifiers

    Chinese Community and Leaders’ Sponsorship for Singapore Schools: Case Studies of the Chinese High School and Raffles Institution

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    The Cultural Legacies of Chinese Schools in Singapore and Malaysia61-79United Kingdo

    Chinese Community and Leaders’ Sponsorship for Singapore Schools – Case Studies of the Chinese High School and Raffles Institution

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    The Cultural Legacies of Chinese Schools in Singapore and Malaysia61-79London & New Yor

    Transparency of a Geographically Distributed Test Platform for Fuel Cell Electric Vehicle Powertrain Systems Based on X-in-the-Loop Approach

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    X-in-the-loop is a new vehicle development and validation method for increasingly complex vehicle systems, which integrates the driver and the environment. In view of recent developments in fuel cell electric vehicle powertrain systems, Tongji University and Karlsruhe Institute of Technology have jointly developed a set of distributed test platforms based on the X-in-the-loop approach. This platform contains models and test equipment for a fuel cell electric vehicle powertrain system. Due to the involvement of remote connection and the Internet, test with connected test benches will suffer great uncertainty cause of signal transfer delay. To figure out this uncertainty, the concept of transparency is introduced. Four parameters were selected as transparency parameters in this distributed test platform. These include vehicle speed, fuel cell output power, battery output power, and electric motor torque under several different configuration settings. With the help of transparency theory and statistical methodology, especially Analysis of Variance (ANOVA), the transparency of these four parameters was established, vehicle speed, electric motor torque, battery power, and fuel cell power are affected by network state, the degree of influence is enhanced in turn. Using new defined parametric and non-parametric methods, this paper identifies the statistical significance and the transparency limitations caused by Internet under these several configurations. These methods will generate inputs for developer setting the distributed test configuration. These results will contribute to optimize the process of geographically distributed validation and joint development

    Insights into the formation of chiral second sphere coordination complexes with aromatic tris amines: combined single crystal X-ray crystallography and molecular modeling analyses

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    Bulky methyl groups on the central aromatic ring in chiral isostructural second sphere coordination adducts are crucial for the induction of chirality.</p
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