10 research outputs found
A high purity measurement of Rb​ at SLD
- Author
- Publication venue
- Publication date
- 04/07/1996
- Field of study
Precision measurement of Rb can provide important information about the Standard Model and beyond. SLD has developed a new method for measuring Rb with very high purity. This measurement has the lowest systematic error reported to date and future measurements using this method will likely have the lowest total uncertainty. This paper will be divided into the five sections: introduction, hardware, topological vertexing tag method, results and conclusions. The introduction will discuss the importance of Rb and the problems with other measurement techniques. The hardware section will give a brief description of the SLC/SLD system concentrating on its advantages over LEP. An outlook towards the future of SLD Rb measurements will be included in the conclusions
Multiple novel prostate cancer susceptibility signals identified by fine-mapping of known risk loci among Europeans
- Author
- Abbasi Z
- Abdul-Hamid M Akhlil
- Abel Paul D
- Abrams Paul H
- Adab Fawzi A
- Adamson Andrew
- Adeyoju A
- Adolfson Jan
- Afzal Naveed
- Ahiaku Ernest K N
- Ahmed Munir
- Al Sudani Mohammed L
- Al-Samarraie Amir S M
- Al-Samerraie [Unknown]
- Al-Singary Waleed
- Al-Sudani [Unknown]
- Alcock Christopher
- Alexander Kimberly
- Ali Zulfiqar
- Almond David J
- Alonzi Roberto
- Aly Markus
- Amin Al Olama Ali
- Anderson John
- Andrews Henry
- Andrews Steven
- Anjum Iqbal
- Anson Ken
- Anyamene Nicola A
- Apakama Ike
- Aparcia F
- Archbold J A A
- Arndt Volker
- Ash D
- Ashford Richard F U
- Auvinen Anssi
- Azzabi A
- Badenoch David
- Bahl Amit
- Bailey Karen
- Bailey M J
- Ball Andrew J
- Banerjee G
- Barber Jim
- Barber N
- Baria [Unknown]
- Barnes Douglas G
- Barros-Silva Joao
- Barwell Julian
- Bashir J
- Basu Pradip
- Bates Christopher A
- Batra Jyotsna
- Bax N A
- Baxter-Smith D
- Bdesha Amar
- Beacock Christopher J M
- Beaney Ronald P
- Beard Ralph
- Beatty John D
- Beck Rupert
- Beese Gail
- Beesley Sharon
- Bell C Richard W
- Bellringer James
- Benlloch Garcia Sara
- Benson Richard
- Beresford [Unknown]
- Bevis Christopher R A
- Bhana Rajanee
- Bhanot S
- Bhatnagar A
- Bhatt R I
- Birch Brian
- Birtle Alison
- Bishop M
- Biyani C Shekhar
- Blacklock A R E
- Blades Rosemary
- Bliss Peter
- Bloomfield David J
- Boddy S
- Bollina Prasad
- Bonnington Sue
- Booth C M
- Bose Pradeep
- Bott Michael C
- Bottomley David
- Boucher Nigel R
- Bowen J
- Bower Mark
- Bowsher W G
- Boyd P J R
- Bradshaw Lynne
- Bramble F James
- Brenner Hermann
- Brewster Simon F
- Briggs Tim
- Brock Cathryn
- Brock Sue
- Bromage Stephen
- Broms Michael
- Brough Richard
- Brown Andrew A
- Brown Paul
- Brown Paul M
- Brown Richard
- Brown Stephen
- Browning Tony J
- Bryan N
- Burgess Neil A
- Burns-Cox Nicholas
- Butterbach Katja
- Butterworth Paul C
- Cahill D
- Callaghan P S
- Calleary John
- Calleja M
- Calman Frances
- Camilleri Philip
- Campbell Alister
- Cannon Andrea
- Cannon-Albright Lisa
- Carnell Dawn M
- Carr T W
- Carter Adam C
- Carter Charles J M
- Carter Simon
- Castle Bruce M
- Catto James
- Cavalli-Bjoerkman Carin
- Chadwick David
- Chahal Rohit
- Chakraborti P
- Chappell [Unknown]
- Charig C
- Chetiyawardana Anula D
- Chilton Christopher
- Chinegwundoh F I
- Chong Irene
- Choudhury Ananya
- Chow Wai-Man
- Christmas Timothy J
- Christova Svetlana
- Churn Mark J
- Cieza-Borrella Clara
- Clarke Noel W
- Clavijo-Eisele Jorge
- Clements Judith A
- Coe M
- Coetzee Gerhard A
- Cohen N P
- Coker C
- Cole David J
- Cole O
- Cole Trevor
- Collins Angus
- Collins Gerald
- Collinson Matthew
- Conn I
- Connell C
- Conti David V
- Cook Audrey
- Cook Margaret
- Cooke Peter
- Cooksey Graeme
- Coombs L
- Cooper Debbie
- Copland Robert F
- Cornaby Andrew J
- Cornford P A
- Corolis [Unknown]
- Corr John
- Costello C B
- Coull Mrs N
- Cowan Richard
- Cox Angela
- Cox Robert
- Coyle C
- Crew Jeremy
- Crisp John C
- Cross W
- Cruger Dorthe
- Crundwell Malcolm
- Cummings [Unknown]
- Cybulski Cezary
- Dadaev Tokhir
- Dahar Nazeer
- Daniel Francis N
- Darrad J
- Daruwala Pallon
- Das Gautam
- Datta Shibendra
- Davidson S
- Davies Joseph
- Davis Michael
- Davison Owen W
- Dawkins Guy
- Dawson Chris
- De Bolla Alan R
- Dearnaley David
- Desai Ken M
- Deutsch George P
- Dick John
- Dickinson Andrew J
- Dickson Jeanette
- Dikov Tihomir
- Dinneen Michael
- Dixit Sanjay
- Dobbs H Jane
- Doble A
- Doble Andrew
- Dodds David
- Doherty Alan
- Donaldson P
- Donovan Jenny L
- Dooldeniya M
- Douglas S Fiona
- Down Liz
- Drake [Unknown]
- Duchesne Gill M
- Duffy Peter
- Dunn Michael
- Dunsmuir W D
- Durkan Garrett
- Durrani Sajid K
- Easton Douglas
- Eaton Alan C
- Eccles Diane
- Eckert Allison
- Eddy B
- Eden C D
- Edwards J
- Eeles Rosalind A
- El-Modir A
- Elkabir Jeremy
- Elliott Emma
- Elliott P Tony
- Ellis B W
- Ellis R
- Elves Andrew W S
- Elwell Christine
- Emberton Mark
- Emmerson Louise
- England Roland C D
- Errington R D
- Evans D Gareth
- Falconer Alison
- Fawcett Derek
- Featherston C
- Featherstone Carolyn J
- Feggetter Jeremy
- Ferguson C
- Fermont D
- Ferro Michael
- Fisher Cyril
- Fitzgerald Liesel
- Fitzgerlad Liesel M
- Fletcher Matthew
- Folkes A
- Ford Trevor F
- Foster Paul W
- Franks Kevin N
- Freedman Mathew
- Frim Olivera
- Gale Joanna
- Gallegos Christopher
- Gelister James S
- George Anne
- Ghana [Unknown]
- Gibbs Stephanie
- Gilbert Hugh
- Giles Graham G
- Gillatt David
- Glaholm John
- Glass Jonathan M
- Glenister James
- Goode Thomas D
- Gordon E M
- Govindasami Koveela
- Gower Richard L
- Graham John
- Green Damian
- Greenland Jonathan
- Grieve Robert
- Griffiths Thomas R L
- Gronberg Henrik
- Gujral Sandy
- Gupta Nishi
- Gurun Riza Murat
- Gustafsson Sven
- Guy Michelle
- Guy Peter J
- Haiman Christopher A
- Haldar Neil
- Halder N
- Haley James
- Hamdy F C
- Hamdy Freddie
- Hamilton C
- Hammonds John
- Hampson S J
- Hanbury Damien C
- Hardman P D John
- Harland Stephen J
- Harney John M
- Harper Peter
- Harris D
- Harris Sarah
- Harrison G S M
- Harriss D R
- Harvey-Hills N
- Hawkyard Simon
- Hazel Steve
- Hazelett Dennis J
- Heath Catherine M
- Heathcote Peter
- Hehir Michael
- Hellawell Giles O
- Henderson Brian E
- Hendry David
- Henley Mike
- Henrique Rui
- Henry Ann
- Herbert Pippa
- Herkommer Kathleen
- Hetherington John
- Hickish Tamas
- Hicks James A
- Hilman Serena
- Hindley Richard
- Hindmarsh John R
- Hines John
- Hingorani M
- Ho Edwin T S
- Hodgson Shirley
- Hoffman U
- Holden David
- Holding Peter
- Hollingdale A
- Hollins Graham W
- Holmes Simon A V
- Holt Sarah
- Hopper John L
- Horan Gail
- Horwich Alan
- Hoskin Peter
- Howell Graham P
- Howson Joanne
- Hrouda D
- Huddart Robert
- Hudson Liz
- Hughes Michael
- Hughes Owen
- Hughes Rob
- Humber Caroline
- Iacovou John W
- Ibrahim A
- Inglis John A
- Irving Stuart
- Irwin C
- Iversen Peter
- Izatt Louise
- Izegbu Victor
- Jameel Basharat
- James Michael J
- James N
- James R Lester
- Javle Pradip
- Jenkins P
- Jhavar Sameer
- Johansson Jan-Erik
- Jones Chris R
- Jones David A
- Jones Gareth
- Jones Mandy
- Joseph J
- Joss Shelagh
- Jugurnauth-Little Sara
- Kachakova Darina
- Kaisary Amir
- Kaliski Alexandre L
- Kaneva Radka
- Kapur G
- Karim O
- Karlsson Ami
- Karp Stephen J
- Kedda Mary-Anne
- Keeley F X
- Kelkar Anand R
- Kelleher J P
- Kelly John
- Kenwrick Sue
- Kerr Kris
- Key Tim J
- Khan F
- Khaw Kay-Tee
- Khoo Vincent
- Kibel Adam S
- Kierzek Andrzej
- Kimber Rachel M
- Kinder R
- Kirby Roger S
- Kirk David
- Kirkbride Peter
- Kirollos Magdi M
- Klarskov Peter
- Kluzniak Wojciech
- Kockelbergh Roger
- Koenig Philip C W C
- Kooiman Gordon G
- Koreich O
- Kote-Jarai Zsofia
- Koupparis Anthony
- Kourah Mohamed
- Kraus Sigurd
- Kujala Paula
- Kujawa Magda L
- Kulkarni Ravi
- Kumar M
- Kumar Rajeev
- Kunkler Ian H
- Kynaston H
- Kynaston Howard
- Lachlan Katherine L
- Laing Robert
- Lalloo Fiona
- Lancashire M
- Lane Athene
- Langley Stephen E M
- Laniado Marc
- Larner T R
- Lau Maurice W
- Lawrence W T
- Lawson Anne
- Le Roux Pieter J
- Leader Mary
- Lee A
- Lee J O
- Lee L
- Lemburger R John
- Lennon Teresa
- Leone Priscilla
- Leongamornlert Daniel
- Lester Jason
- Leung Hing
- Lewis D Christopher
- Lewis J
- Li Qiuyan
- Lim Hui-Yi
- Lin Hui-Yi
- Liston Thomas
- Livni Naomi
- Livsey Jacqueline
- Lloyd S
- Locke Imogen
- Lodge Richard
- Logue John
- Longmuir Mark
- Lophatananon Artitaya
- Lophatonanon Artitaya
- Lubinski Jan
- Lucas Malcolm G
- Luedeke Manuel
- Luscombe C J
- Lydon Anna
- Lynch Michael
- Lynn Naing N K
- Lyons Norma
- MacDermott James P A
- Macdonagh Ruaraidh P
- Macdonald [Unknown]
- Madaan Sanjeev
- Madhava Kudingila R
- Maeaettaenen Liisa
- Maguire Joseph
- Maher E R
- Mahmood Rana
- Maia Sofia
- Maier Christiane
- Mair Graeme H M
- Malone Greg
- Malone Peter R
- Mangar Stephen A
- Mantle Mark
- Mark I
- Marsden Gemma
- Mason M D
- Mason Malcolm
- Mason Robert
- Matanhelia [Unknown]
- Matenhelia Shyam
- Matthews Philip N
- McAleese J
- McBride Donna
- Mcdonnell Shannon K
- McDonnell Shannon K
- McFarlane Jonathan
- McGrath [Unknown]
- McIlhenny Craig
- McInerney Paul
- McIntosh Gregor
- McKinna F
- McLaren Duncan
- McLarty Esther
- McMenemin Rhona
- McNeill Alan
- McNicholas T A
- Meddings Robert N
- Mee A David
- Melcher Lucinda
- Memon [Unknown]
- Menzes Pravin
- Michael Agnieszka
- Miller Marek
- Mills Robert
- Mitchell S
- Mitev Vanio
- Mithal Natasha
- Mitkova Atanaska
- Mitra Anita
- Mobb Gillian E
- Moffat Leslie E F
- Mokete [Unknown]
- Money-Kyrle Julian
- Montgomery Bruce
- Moody Hilary
- Moody Martin P
- Morgan Angela
- Morley Roland
- Morris Sean B
- Morrison Patrick
- Mort Diana
- Mostafid Amir H
- Motiwala Hanif
- Mufti Gulzar
- Muir Gordon
- Muir Kenneth
- Mumtaz Faiz
- Murphy Michael
- Murray Alexandra
- Murray Keith W
- Murrell Shirley
- Murtola Teemu
- Muthukumar D
- Naerger Harry
- Namasivayam Siva
- Nargund Vinod
- Nawrocki [Unknown]
- Neal David E
- Neilson Donald
- Nethersell A
- Newby Jacqueline C
- Newman Hugh
- Newton R
- Nielsen Sune F
- Nordestgaard Børge G
- O'Boyle P J
- O'Brien J
- O'Brien Tim S
- O'Donnell H
- O'Donoghue E
- O'Donoghue Neil
- O'Reilly P
- O'Rourke J S
- O'Sullivan Joe
- O'Sullivan Patricia
- Oakley Neil
- Ogden Chris
- Ohja Hemant
- Oliver Tim
- Omara Tracy
- Ong Eng K
- Osborn David
- Ostler Peter
- Owen J
- Palfrey Edward
- Panades Miguel
- Panakis Niki
- Pancharatnam M
- Pandha Hardev
- Pantelides Michalakis L
- Panwar U
- Parikh Omi
- Park Hyun
- Park Jong Y
- Parker Chris
- Parker Christopher H
- Parys Bohdan T
- Pascoe Sarah
- Pashayan Nora
- Patel Anup
- Paterson Joan
- Pathack S
- Pati Jhumur
- Patterson Helen
- Pattu [Unknown]
- Paul A
- Paul Alan
- Paulo Paula
- Payne Heather
- Peake David
- Pedersen John
- Pedley I
- Pengelly A
- Peracha Amjad M
- Perry Matthew
- Persad Raj
- Peters John
- Pharoah Paul
- Philp N H
- Philp T
- Pickering Lisa M
- Pigott Katharine
- Pinto Pedro
- Plail R
- Plowman P Nicholas
- Pocock Richard D
- Pope A J
- Popert Rick
- Popov Elenko
- Porter Tim
- Potter John M
- Pow-Sang Julio
- Powell Christopher
- Powell Philip
- Powles Thomas B
- Prasad Krishna
- Prasad Seshadri Sri
- Prejbisz J W
- Prescott Stephen
- Protheroe Andrew
- Qureshi Khaver N
- Raby Nigel
- Radlein Selina
- Ragavan Narasimhan
- Raju Palaniappa G S
- Ramachandra Prakash B
- Raman R
- Rane Abhay
- Rankin Julia
- Rao Y
- Ratan Hari L
- Ravi Ramachandran
- Ravishankar K
- Read [Unknown]
- Reddy Paul J
- Rimington Peter R
- Rinckleb Antje
- Rincon Maria
- Riska Shaun
- Ritchie Peter A
- Roberts J Trevor
- Robertson Andrew
- Robinson Angus
- Robinson Anne C
- Robinson Lee Q
- Rochester Mark A
- Roder Andreas
- Rogers P B
- Rosario Derek
- Rosenbaum Tomas P
- Rothwell Neil
- Rowbotham Carl
- Rowe [Unknown]
- Rowley Kathryn
- Ruddy Deborah
- Rundle John
- Russell John M
- Ryan P G
- Sabharwal A
- Saggar Anand K
- Samanci Ali
- Sangar Vijay K
- Santos Joana
- Saunders Edward J
- Saunders Pamela
- Sawyer Emma J
- Saxby M F
- Schaid Daniel J
- Schleutker Johanna
- Schumacher Fredrick
- Schwaibold Hartwig
- Scoble John E
- Scrase Christopher
- Selim [Unknown]
- Sellers Thomas
- Sells Henry
- Sethia Krishna K
- Severi Gianluca
- Shackley David C
- Shaffer [Unknown]
- Shah Nihil
- Shakespeare D
- Shanley Sue
- Sharma Neerah K
- Sheehan Denise J
- Sherwin Elizabeth
- Shum Poh Lin
- Side Lucy
- Sidek Norma
- Signorello Lisa B
- Sikora Karol
- Simcock R
- Sinclair Andrew M
- Singh Pravin
- Siva M
- Slavov Chavdar
- Smith James
- Smith Michael F
- Sokal Michael
- Sole Graham M
- Southey Melissa C
- Speakman Mark J
- Spiers Alexander
- Spurdle Amanda
- Sreenivasan Thiagarajan
- Srihari Narayanan N
- Srinivasan [Unknown]
- Sriram Rajagopalan
- Staffurth John N
- Stanford Janet L
- Stattin Paer
- Stegmaier Christa
- Stephens Sarah
- Stewart D
- Stockdale Andrew
- Stott Mark A
- Stower M J
- Strachan John R
- Stuart Nicholas S A
- Sugden Elaine
- Summerton Duncan
- Sundar Santhanam
- Sundaram S K
- Suresh Gokarakonda
- Susnerwala Shabbir
- Swami Kuchibhotla S
- Symons Stephanie J
- Syndikus Isabel
- Taari Kimmo
- Tahir Saad
- Tammela Teuvo L
- Tammela Teuvo L J
- Tanquay J
- Taylor J W
- Taylor John W
- Teixeira Manuel R
- Terry T
- Thibodeau Stephen N
- Thomas Robert J
- Thomas Stephen A
- Thompson Alan
- Thompson Pauline
- Thomson Alastair H
- Thurston A
- Tidball Sarah
- Tillmans Lori
- Tilsley Owen
- Tindall Stuart F
- Tipples K
- Tong [Unknown]
- Toussi Hamid
- Toy Elizabeth W
- Travis Ruth C
- Trembath Richard C
- Tulloch David N
- Turner Kevin J
- Turner Megan
- Tweedle James
- Tymrakiewicz Malgorzata
- Tyrell C J
- Umez-Eronini N
- Urwin Graeme H
- Vale Justin A
- Van As [Unknown]
- Van As Nicholas
- Vasanthan Subramaniam
- Vesey Sean
- Vilarino-Varela Maria
- Violet John
- Virdi Jaspal
- Viñuela Ana
- Vlahova Aleksandrina
- Vogel Walther
- Wade Robert
- Wahlfors Tiina
- Waite Katherine
- Walker E M
- Walker Roger
- Wallace David M A
- Wallinder Hans
- Wang Liang
- Watkin Nicholas A
- Watson M E
- Waxman J H
- Waymont Brian
- Weaver Andrew
- Webb Ralph J
- Wedderburn Andrew
- Weischer Maren
- Wells Paula
- Wemyss-Holden G D
- Weston P M T
- Wheatley Duncan
- Whelan P
- Whillis D
- Whitmore Ian
- Wiklund Fredrik
- Wilde Adam D
- Wiles Vicki
- Wilkins Marie
- Wilkinson Rosemary
- Williams John H
- Williams Simon
- Willis Michael
- Wills Michael I
- Wilson J R
- Wilson Richard
- Winkler Mathias H
- Wise Marcus
- Wokozorczyk Dominika
- Wokołorczyk Dominika
- Wood Glenn
- Woodhams Simon
- Woodhouse C
- Woodward Cathryn
- Woolf [Unknown]
- Woolfenden K A
- Worlding Jane
- Wright Mark
- Wu Huihai
- WYLIE [Unknown]
- Wylie James P
- Wynne Chris
- Yeadon Trina
- Zachariah Babu
- Zang Angelika
- Zarkar A
- Zheng Wei
- Publication venue
- 'Oxford University Press (OUP)'
- Publication date
- 01/01/2015
- Field of study
Genome-wide association studies (GWAS) have identified numerous common prostate cancer (PrCa) susceptibility loci. We have
fine-mapped 64 GWAS regions known at the conclusion of the iCOGS study using large-scale genotyping and imputation in
25 723 PrCa cases and 26 274 controls of European ancestry. We detected evidence for multiple independent signals at 16
regions, 12 of which contained additional newly identified significant associations. A single signal comprising a spectrum of
correlated variation was observed at 39 regions; 35 of which are now described by a novel more significantly associated lead SNP,
while the originally reported variant remained as the lead SNP only in 4 regions. We also confirmed two association signals in
Europeans that had been previously reported only in East-Asian GWAS. Based on statistical evidence and linkage disequilibrium
(LD) structure, we have curated and narrowed down the list of the most likely candidate causal variants for each region.
Functional annotation using data from ENCODE filtered for PrCa cell lines and eQTL analysis demonstrated significant
enrichment for overlap with bio-features within this set. By incorporating the novel risk variants identified here alongside the
refined data for existing association signals, we estimate that these loci now explain ∼38.9% of the familial relative risk of PrCa,
an 8.9% improvement over the previously reported GWAS tag SNPs. This suggests that a significant fraction of the heritability of
PrCa may have been hidden during the discovery phase of GWAS, in particular due to the presence of multiple independent
signals within the same regio
Effect of placebo on ambulatory blood pressure monitoring in children
- Author
- B Williams
- C Gimpel
- C Hadtstein
- E Lurbe
- E Urbina
- EA Saleh
- G Mancia
- H Punzi
- IA Khan
- Janice Sullivan
- Jeffrey Blumer
- JM Neutel
- JM Sorof
- JM Sorof
- JM Sorof
- JT Flynn
- Karen Redwine
- Ke Yan
- KL McNiece
- Laura James
- Lee Howard
- M Antal
- P Kardas
- PB Smith
- Pippa Simpson
- RA Preston
- Robert Ward
- S Genovesi
- S Matsuoka
- S Stabouli
- Shun-Hwa Li
- TG Pickering
- Thomas Wells
- Y Tanigawara
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
What Constitutes Evidence for Copyright Policy?
- Author
- A Gowers
- Bengt-Ake Lundvall
- C Waelde
- Charlotte Waelde
- Christian Handke
- D C Washington
- D Mendis
- D Secchi
- Davide Secchi
- E Abrahamson
- E Derclaye
- Estelle Derclaye
- F Homberg
- G Tullock
- H G Wells
- Hasan Bakhshi
- I Hargreaves
- Ipo
- J C Fromer
- J Griffin
- J Karaganis
- J M Keynes
- Jeremy M Silver
- Joost Poort
- Kris Erickson
- L Bently
- Lilian Edwards
- Linda Humphries
- M Favale
- M Kretschmer
- M Kretschmer
- M Kretschmer
- M Kretschmer
- Martin Kretschmer
- N Gilbert
- P Davies
- P Schlesinger
- P Schlesinger
- Paul J. Heald
- Philip Schlesinger
- Pippa Hall
- Pricewaterhousecoopers
- R B Kline
- R F
- R Hooper
- R Hooper
- R Jacob
- R Thaler
- R Towse
- R Towse
- Robin Jacob
- Ruth Towse
- S Siwek
- S Stokes
- S Weston
- Sons Mumford
- Storify Twitter
- Thomas Hoehn
- W Brueggemann
- W Page
- Whitford
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2013
- Field of study
Korruption und Bürgereinstellungen zu Demokratie in Europa: Was ist der empirische Zusammenhang?
- Author
- Aksel Sundström
- Alexander F. Wagner
- André Blais
- Anna Persson
- Armin Schäfer
- Armin Schäfer
- Arnold J. Heidenheimer
- Bo Rothstein
- Bo Rothstein
- Bo Rothstein
- Bo Rothstein
- Bo Rothstein
- Boris Podobnik
- Bruce Gilley
- Bruce Gilley
- Christopher J. Anderson
- Christopher J. Anderson
- Christopher J. Anderson
- Damarys Canache
- Damarys Canache
- Daniel Stockemer
- Daniel Stockemer
- Daniel Treisman
- David Easton
- David Easton
- Eric C. C. Chang
- Eric Uslaner
- Frederick Solt
- G. Bingham Powell
- Gunnar Myrdal
- Jason M. Wells
- Jeffrey A. Karp
- Joel Hellman
- John A. Booth
- John Wilson
- Jonas Linde
- Joseph S Nye
- Kees Aarts
- Keith Jaggers
- Luigi Curini
- Margaret Levi
- Margaret Levi
- Maria Bäck
- Mark E Warren
- Michael Bratton
- Michael Gulbrandtsen
- Michael Johnston
- Mitchell A Seligson
- Paolo Mauro
- Pippa Norris
- Raymond Fisman
- Rebecca Weitz-Shapiro
- Samuel P Huntington
- Sanjeev Gupta
- Stephen Knack
- Susan J. Pharr
- Tatiana Kostadinova
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Feasibility of reporting results of large randomised controlled trials to participants:experience from the Fluoxetine or Control under supervision (FOCUS) trial
- Author
- A Abdul-Hamid
- A Ahmed
- A Ali
- A Annamalai
- A Anthony
- A Asokanathan
- A Azim
- A Bahk
- A Banaras
- A Barry
- A Barugh
- A Bell
- A Benford
- A Bhalla
- A Blight
- A Boulton
- A Bowring
- A Burns
- A Butler
- A Bwalya
- A Cape
- A Chakrabarti
- A Chamberlain
- A Cook
- A Culbert
- A Dainty
- A David
- A Deary
- A DeVeciana
- A Dunne
- A Edwards
- A Espanol
- A Fazal
- A Fields
- A Fleming
- A Frith
- A Gillian
- A Goff
- A Goulding
- A Hague
- A Hamilton
- A Hardwick
- A Hasan
- A Hashmi
- A Hassan
- A Hayes
- A Hedges
- A Hedstrom
- A Hemsley
- A Hill
- A Hogan
- A Holloway
- A House
- A Hynes
- A James
- A Johnson
- A Jones
- A Joyson
- A Keeling
- A Kent
- A Khan
- A Kundu
- A Lush
- A Lyle
- A Maatouk
- A MacRaild
- A Majid
- A Man
- A Maney
- A Manoj
- A Mate
- A Mckenna
- A McLoughlin
- A Metcalf
- A Misra
- A Mohd Nor
- A Mucha
- A Nair
- A Nallasivan
- A Nasar
- A Needle
- A Nicolson
- A OCallaghan
- A Oshodi
- A Pace
- A Parry
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- D Austin
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- David Burgess
- David Stott
- E Ahmed El Nour
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- J Cunningham
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- J Devine
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- J Dube
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- J Foot
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- J Graham
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- J Hakkak
- J Hiden
- J Hindle
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- J Kennedy
- J Keshet-Price
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- J Khaira
- J Laurence
- J Leonard
- J Lowe
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- J Margalef
- J Marigold
- J Mcgee
- J Mcilmoyle
- J Meir
- J Mitchell
- J Nevinson
- J Newman
- J Ngeh
- J OConnell
- J Pagan
- J Palmones
- J Paterson
- J Perry
- J Peters
- J Price
- J Pryor
- J Purcell
- J Putteril
- J Ritchie
- J Roberts
- J Rowe
- J Schmit
- J Scott
- J Selvarajah
- J Sesay
- J Sharma
- J Simpson
- J Skewes
- J Skwarski
- J Spurway
- J Stephenson
- J Stewart
- J Sword
- J Tandy
- J Thompson
- J Topliffe
- J Turfrey
- J Vassallo
- J Walford
- J Ward
- J Westcott
- J Westmoreland
- J White
- J Wightman
- J Willson
- J Wilson
- J Wong
- Judith Williamson
- K Adie
- K Ahlquist
- K Ali
- K Amor
- K Bharaj
- K Bond
- K Bunworth
- K Burton
- K Chan
- K Chatterjee
- K Collins
- K Crabtree
- K Dakin
- K Dennett
- K Dodsworth
- K Dynan
- K Elliott
- K Endean
- K Finney
- K Fotherby
- K Griffiths
- K Gupwell
- K Haque
- K Harkness
- K Harris
- K Hayes
- K Innes
- K Jennings-Preece
- K Jones
- K Kauldhar
- K Kavanagh
- K Kawafi
- K Kennedy
- K Littlewood
- K Mahawish
- K Marks
- K McCormick
- K McLeish
- K Mears
- K Miller
- K Mitchelson
- K Montgomery
- K Moore
- K Nagaratnam
- K Netherton
- K Ng
- K Norton
- K Nyo
- K Ofori
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- K Patel
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- K Subramanian
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- K Yip
- Karen Innes
- L Abbott
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- L Brookes
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- L Brown
- L Burgess
- L Carr
- L Choy
- L Connell
- L Cooper
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- L De Michele Hock
- L Denham
- L Denny
- L Dixon
- L Doughty
- L Dow
- L Eldridge
- L Fergey
- L Foote
- L Francis
- L Garcia-Alen
- L Goldenberg
- L Gordon
- L Graham
- L Greenhalgh
- L Guthrie
- L Harrison
- L Hazell
- L Hill
- L Hough
- L Howaniec
- L Hunt
- L hurley
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- L Jackson
- L Johnson
- L Kalathil
- L Kamuriwo
- L Kemp
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- L Lane
- L Latter
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- L Mokoena
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- L Southworth
- L Stephenson
- L Sykes
- L Thomas
- L Tonks
- L Trainor
- L Turner
- L Wade
- L Whitehead
- L Wilson
- L Wood
- L Wright
- L Zhang
- M Abdul-Saheb
- M Augustin
- M Barber
- M Bates
- M Bhandari
- M Bhargava
- M Bhattad
- M Bokhari
- M Bolton
- M Brezitski
- M Burn
- M Burova
- M Carpenter
- M Chauhan
- M Christie
- M Cooper
- M Couser
- M Crofts
- M Davy
- M Dhakal
- M Donninson
- M Drake
- M DSouza
- M Duffy
- M Eastwood
- M Edwards
- M Elliott
- M Fairweather
- M Goldsworthy
- M Goorah
- M Hackett
- M Haley
- M Hancevic
- M Haque
- M Hargreaves
- M Haritakis
- M Harper
- M Harvey
- M Hassan
- M Hawkes-Blackburn
- M Holden
- M Holland
- M Hooley
- M Hough
- M Hughes
- M Hussain
- M James
- M Kalita
- M Kambafwile
- M Keeling
- M Keltos
- M Khan
- M Kidd
- M Krasinska-Chavez
- M Krishnan
- M Kyu
- M Landicho
- M Lang
- M Langley
- M Lepore
- M MacLeod
- M Marner
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- M Naeem
- M O Neill
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- M Osborn
- M Pitt
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- M Randall
- M Robinson
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- M Scott
- M Sein
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- M Simpson
- M Soliman
- M Srinivasan
- M Stirling
- M Tate
- M Tribbeck
- M Villaruel
- M Wands
- M Ward
- M Weinling
- M Wilkinson
- M Williams
- M Willmot
- Maree Hackett
- Martin Dennis
- N Abano
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- N Al-Samarrai
- N Chapman
- N Chattha
- N Chopra
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- N Hannon
- N Haque
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- N Mohammed
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- N Sattar
- N Schumacher
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- N Smyth
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- N Upton
- N Weir
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- O Chohan
- O David
- O Omodunbi
- O Quinn
- O Redjep
- O Speirs
- P Aruldoss
- P Ashcroft
- P Baker
- P Brown
- P Clark Brown
- P Cook
- P Cooper
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- P Cottrell
- P Cox
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- P Dangri
- P Datta
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- P Ferdinand
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- P Gamble
- P Gompertz
- P Guyler
- P Harlekar
- P Harman
- P Hollinshead
- P Jacob
- P Jones
- P Kumar
- P Langhorne
- P Lopez
- P Mathieson
- P Mccann
- P Mudd
- P Murphy
- P Nair
- P Nicholas
- P OMahony
- P Rana
- P Reidy
- P Rushworth
- P Smalley
- P Sutton
- P Tam
- P Taylor
- P Thompson
- P Walker
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- P Whitmore
- P Wilkinson
- P Willcoxson
- P Wood
- Peter Sandercock
- Pippa Tyrrell
- R Anderson
- R Bakawala
- R Bathula
- R Beard
- R Bellfield
- R Blackburn
- R Boulton
- R Bower
- R Bowers
- R Brown
- R Buchan
- R Burnip
- R Butler
- R Cain
- R Carpio
- R Chapman
- R Clarke
- R Cowan
- R Creeden
- R Curwen
- R Davey
- R Durairaj
- R Erande
- R Evans
- R Fennelly
- R Fong
- R Fraser
- R Furness
- R Gallifent
- R Ghatala
- R Ghulam
- R Glover
- R Greenwood
- R Hayman
- R Hungwe
- R Keskeys
- R Kirthivasan
- R Krishnamurthy
- R Ladner
- R Lampard
- R Lindert
- R Loosley
- R Luder
- R Miller
- R Mir
- R Namushi
- R Nari
- R Needle
- R Nendick
- R Orath Prabakaran
- R Parakramawansha
- R Partridge
- R Patel
- R Pattni
- R Paulton
- R Pereira
- R Rangasamy
- R Rayessa
- R Robinson
- R Rodriguez
- R Said
- R Saksena
- R Sanyal
- R Scott
- R Shah
- R Sivakumar
- R Spencer
- R Tangney
- R Teal
- R Tongue
- R Varquez
- R Vowden
- R Walker
- R Warinton
- R Whiting
- R Williams
- R Wills
- R Wynn-Williams
- R Young
- Ray French
- S Abubakar
- S Ahmed
- S Al Hussayni
- S Alam
- S Amlani
- S Arif
- S Bell
- S Besley
- S Billingham
- S Blane
- S Bloom
- S Board
- S Bradfield
- S Brammer
- S Brotheridge
- S Brown
- S Burgess
- S Butler
- S Caine
- S Carson
- S Chandler
- S Chaplin
- S Clarke
- S Clayton
- S Collins
- S Cook
- S Crisp
- S Crothers
- S Cuddy
- S Dabbagh
- S Davenport
- S Dayal
- S De Bruijn
- S Dealing
- S Dhar
- S Dima
- S Donaldson
- S Duberley
- S Dunn
- S Duty
- S Dyer
- S Egerton
- S El Tawil
- S Elitova
- S Ellis
- S Evans
- S Finlay
- S Fung Lo
- S Funnell
- S Gohil
- S Goshawk
- S Graham
- S Hagan
- S Haider
- S Haigh
- S Hervey
- S Holland
- S Honour
- S Humphrey
- S Hurdowar
- S Ispoglou
- S Jackson
- S Johnston
- S Keenan
- S Kelavkar
- S Kelly
- S Khan
- S Kidd
- S Kullane
- S Kumar
- S Kunhunny
- S Leach
- S Leason
- S Levy
- S Lijko
- S Lock
- S Loganathan
- S Mahalingam
- S Maiden
- S Markova
- S Marshall
- S Mavinamane
- S Mawer
- S McAuley
- S Mcdonald
- S McKenna
- S Meenakshisundaram
- S Melander
- S Mintias
- S Morrison
- S Mumani
- S Mutton
- S Naqvi
- S Nelson
- S Noor
- S Oakley
- S OConnell
- S Omer
- S Orr
- S Parkinson
- S Patel
- S Pound
- S Power
- S Prasad
- S Punekar
- S Punnoose
- S Qamar
- S Ragab
- S Raj
- S Ramachandra
- S Rashmi
- S Raza
- S Razak
- S Ross
- S Sangaralingham
- S Seagrave
- S Sethuraman
- S Shah
- S Shahzad
- S Shanu
- S Sharon
- S Sharpe
- S Smolen
- S Stevens
- S Stevenson
- S Sultan
- S Sundayi
- S Tauro
- S Thornthwaite
- S Tilbey
- S Tinsley
- S Todd
- S Trippier
- S Tsang
- S Tucker
- S Tysoe
- S Valentine
- S Walker
- S Weatherby
- S Whitehouse
- S Whitworth
- S Williams
- S Williamson
- S Wong
- S Young
- Steff Lewis
- T Adedoyin
- T Anjum
- T Beadling
- T Black
- T Carter
- T Cassidy
- T Chapter
- T Corbett
- T Dowling
- T Duckett
- T Edmunds
- T England
- T Fluskey
- T Garcia
- T Hammond
- T Hlaing
- T Jackson
- T James
- T Jones
- T Khan
- T Lawrence
- T Levett
- T Loganathan
- T Nishiyama
- T Sandell
- T Sargent
- T Smith
- T Soe
- T Tarkas
- T Thirugnana-Chandran
- T Trugeon-Smith
- T Webb
- T Webster
- U Ghani
- U Hamid
- U Khan
- U Pallikona
- U Sukys
- U Umasankar
- V Balasubramanian
- V Croome
- V Cvoro
- V DiMartino
- V Hankin
- V Johnson
- V Jones
- V Le
- V Lowthorpe
- V Murray
- V Nadarajan
- V Pressly
- V Sudkeo
- V Sutton
- V Taylor
- V Withers
- Veronica Murray
- W Abbott
- W Alvares
- W Gaba
- W Golding
- W Rutherford
- W Smith
- W Wareing
- X Huang
- Y Abousleiman
- Y Begum
- Y Chin
- Y Chun
- Y Davies
- Y Neves-Silva
- Y Pai
- Z Ahmed
- Z Mellor
- Publication venue
- 'BMJ'
- Publication date
- 01/11/2020
- Field of study
Objectives Informing research participants of the results of studies in which they took part is viewed as an ethical imperative. However, there is little guidance in the literature about how to do this. The Fluoxetine Or Control Under Supervision trial randomised 3127 patients with a recent acute stroke to 6 months of fluoxetine or placebo and was published in the Lancet on 5 December 2018. The trial team decided to inform the participants of the results at exactly the same time as the Lancet publication, and also whether they had been allocated fluoxetine or placebo. In this report, we describe how we informed participants of the results.Design In the 6-month and 12-month follow-up questionnaires, we invited participants to provide an email address if they wished to be informed of the results of the trial. We re-opened our trial telephone helpline between 5 December 2018 and 31 March 2019.Setting UK stroke services.Participants 3127 participants were randomised. 2847 returned 6-month follow-up forms and 2703 returned 12-month follow-up forms; the remaining participants had died (380), withdrawn consent or did not respond.Results Of those returning follow-up questionnaires, a total of 1845 email addresses were provided and a further 50 people requested results to be sent by post. Results were sent to all email and postal addresses provided; 309 emails were returned unrecognised. Seventeen people replied, of whom three called the helpline and the rest responded by email.Conclusion It is feasible to disseminate results of large trials to research participants, though only around 60% of those randomised wanted to receive the results. The system we developed was efficient and required very little resource, and could be replicated by trialists in the future.Trial registration number ISRCTN83290762; Post-results
Methods to systematically review and meta-analyse observational studies: a systematic scoping review of recommendations
- Author
- A Blair
- A Khoshdel
- A Liberati
- A Thornton
- AC Tricco
- AD Furlan
- AF Hernandez
- AJ Sutton
- AJ Sutton
- AM O’Connor
- AR Lemeshow
- AS Doria
- B Takkouche
- BH Thomas
- C Fraser
- C Robertson
- C Stansfield
- C Tufanaru
- Catrina Mugglin
- CD Scales
- CE McCarron
- CM Friedenreich
- D Ashford
- D Chambers
- D Price
- DF Stroup
- DL Weeks
- DO Martin
- DS MacDonald-Jankowski
- EF Funai
- G Davey Smith
- G Davey Smith
- G Salanti
- G Salanti
- GA Colditz
- GA Wells
- GH Guyatt
- GH Guyatt
- GH Guyatt
- GH Guyatt
- GS Sagoo
- H Austin
- H Balshem
- H Kuper
- HJ Schünemann
- HL Colquhoun
- J Horton
- J Lau
- J Thompson
- JA Sterne
- JC Valentine
- JJ Shuster
- JP Ioannidis
- JPT Higgins
- K Abrams
- L Manchikanti
- LM Tak
- M Egger
- M Egger
- M Egger
- M Pladevall-Vila
- M Zwahlen
- Maddalena D’Addario
- Matthias Egger
- MDJ Peters
- MJ Page
- ML Winegardner
- Monika Mueller
- MP Zeegers
- Myriam Cevallos
- N Black
- N Chaiyakunapruk
- N Hartemink
- N Simunovic
- O Wong
- Olaf Dekkers
- OW Souverein
- P Herbison
- P Ravani
- P Wille-Jorgensen
- PE Verde
- Pippa Scott
- R Rosenthal
- RB Haynes
- RJ Lilford
- RL Tweedie
- S Golder
- S Greenland
- S Moola
- S Sanderson
- S Thompson
- SE Brockwell
- SG Thompson
- SJ Smith
- SL Normand
- SL Norris
- SS Mahid
- T Dwyer
- T Shamliyan
- TC Prevost
- V Moreno
- W Zingg
- WC Wong
- YK Loke
- YK Loke
- Z Munn
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Whole-genome sequencing reveals host factors underlying critical COVID-19
- Author
- Abd Elghafar Mohamed S.
- Abdel-Aziz Mahmoud
- Abdelrazik Marwa
- Abdollahi Hamed
- Abdullah T.
- Abecasis Goncalo
- Abedalthagafi M.
- Abel Lynn
- Abernathy C.
- Abraheem Azmeralde
- Abul-Husn Noura S.
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- Whiteley Simon
- Whiteside J.
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- Whitton Christopher
- Whyte Clare
- Wicks S.J.
- Wilby Elizabeth
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- Woodyatt Wiesia
- Woolley A.E.
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- Wrobel Nicola
- Wu Yang
- Wulandari R.
- Wyllie D.H.
- Wynter I.
- Xavier Kugan
- Xue X.
- Yadav A.
- Yang Jian
- Yassen Amr M.
- Yates Brian
- Ye C.
- Yun Nikki
- Zainy Tala
- Zak Anne
- Zaki Ahmed
- Zamikula J.
- Zanella I.
- Zborowski A.C.
- Zeberg Hugo
- Zechner Marie
- Zguro K.
- Zhang M.
- Zhao J.H.
- Zheng Chenqing
- Zhou W.
- Zitter L.
- Zlatopolsky Menachem
- Zongo Olivier
- Zucchi P.
- Zyndorf Marissa
- Zöllner S.
- Åsvold Bjørn Olav
- Publication venue
- Publication date
- 01/01/2022
- Field of study
Altres ajuts: Department of Health and Social Care (DHSC); Illumina; LifeArc; Medical Research Council (MRC); UKRI; Sepsis Research (the Fiona Elizabeth Agnew Trust); the Intensive Care Society, Wellcome Trust Senior Research Fellowship (223164/Z/21/Z); BBSRC Institute Program Support Grant to the Roslin Institute (BBS/E/D/20002172, BBS/E/D/10002070, BBS/E/D/30002275); UKRI grants (MC_PC_20004, MC_PC_19025, MC_PC_1905, MRNO2995X/1); UK Research and Innovation (MC_PC_20029); the Wellcome PhD training fellowship for clinicians (204979/Z/16/Z); the Edinburgh Clinical Academic Track (ECAT) programme; the National Institute for Health Research, the Wellcome Trust; the MRC; Cancer Research UK; the DHSC; NHS England; the Smilow family; the National Center for Advancing Translational Sciences of the National Institutes of Health (CTSA award number UL1TR001878); the Perelman School of Medicine at the University of Pennsylvania; National Institute on Aging (NIA U01AG009740); the National Institute on Aging (RC2 AG036495, RC4 AG039029); the Common Fund of the Office of the Director of the National Institutes of Health; NCI; NHGRI; NHLBI; NIDA; NIMH; NINDS.Critical COVID-19 is caused by immune-mediated inflammatory lung injury. Host genetic variation influences the development of illness requiring critical care or hospitalization after infection with SARS-CoV-2. The GenOMICC (Genetics of Mortality in Critical Care) study enables the comparison of genomes from individuals who are critically ill with those of population controls to find underlying disease mechanisms. Here we use whole-genome sequencing in 7,491 critically ill individuals compared with 48,400 controls to discover and replicate 23 independent variants that significantly predispose to critical COVID-19. We identify 16 new independent associations, including variants within genes that are involved in interferon signalling (IL10RB and PLSCR1), leucocyte differentiation (BCL11A) and blood-type antigen secretor status (FUT2). Using transcriptome-wide association and colocalization to infer the effect of gene expression on disease severity, we find evidence that implicates multiple genes-including reduced expression of a membrane flippase (ATP11A), and increased expression of a mucin (MUC1)-in critical disease. Mendelian randomization provides evidence in support of causal roles for myeloid cell adhesion molecules (SELE, ICAM5 and CD209) and the coagulation factor F8, all of which are potentially druggable targets. Our results are broadly consistent with a multi-component model of COVID-19 pathophysiology, in which at least two distinct mechanisms can predispose to life-threatening disease: failure to control viral replication; or an enhanced tendency towards pulmonary inflammation and intravascular coagulation. We show that comparison between cases of critical illness and population controls is highly efficient for the detection of therapeutically relevant mechanisms of disease
Multiple loci on 8q24 associated with prostate cancer susceptibility
- Author
- Abrams Paul H
- Adamson Andrew
- Adeyoju A
- Afzal N
- Ahiaku Ernest K. N
- Ahmed Munir
- Al Olama Ali Amin
- Al-Samerraie
- Alcock Christopher
- Anderson John
- Andrews Henry
- Andrews Steven
- Anjum Iqbal
- Anson Ken
- Apakama Ike
- Aparcia F
- Archbold J. A. A
- Ardern-Jones Audrey T
- Ash D
- Ashford Richard F. U
- Badenoch David
- Bahl Amit
- Bailey Karen
- Bailey M. J
- Ball Andrew J
- Bancroft E
- Banerjee G
- Barber Jim
- Barber N
- Baria
- Barnes Douglas G
- Barwell Julian
- Basu Pradip
- Bates Christopher A
- Bax N. A
- Baxter-Smith D
- Beacock Christopher
- Beaney Ronald P
- Beard Ralph
- Beck Rupert
- Beese Gail
- Beesley Sharon
- Bellringer James
- Benson Richard
- Bhatt R. I
- Birch Brian
- Birtle Alison
- Bishop M
- Biyani C. Shekhar
- Blacklock A. R. E
- Blades Rosemary
- Bloomfield David J
- Bollina Prasad
- Bonnington Sue
- Booth C. M
- Bose Pradeep
- Bottomley David
- Boucher Nigel R
- Bower Mark
- Bowsher W. G
- Boyd P. J. R
- Bramble F. James
- Brewster Simon F
- Briggs Tim
- Brock Cathryn
- Brock Sue
- Brough Richard
- Brown Paul M
- Brown Richard
- Brown Stephen
- Browning Tony J
- Butterworth Paul C
- Cahill D
- Callaghan P. S
- Calman Frances
- Campbell Alister
- Carnell Dawn M
- Carr T. W
- Carter Adam
- Carter Charles J. M
- Carter Simon
- Castle Bruce M
- Chadwick David
- Chakraborti P
- Charig C
- Chetiyawardana Anula D
- Chilton Christopher
- Chinegwundoh Francis I
- Chong Irene
- Chow Wai-Man
- Christmas Timothy J
- Churn Mark J
- Clarke Noel W
- Coe M
- Cohen N. P
- Coker C
- Cole David J
- Cole O
- Cole Trevor
- Collins Gerald
- Collinson Matthew
- Conn I
- Connell C
- Cooke Peter
- Coombs L
- Cooper Colin
- Cooper Debbie
- Copland Robert F
- Cornaby Andrew J
- Cornford P. A
- Corolis
- Corr John
- Costello C. B
- Cowan Richard
- Cox Robert
- Coyle C
- Crisp John C
- Cruger Dorthe
- Crundwell Malcolm
- Cummings
- Dahar Nazeer
- Daruwala Pallon
- Datta Shibendra
- Davidson S
- Davies Joseph
- Davis Michael
- Davison Owen W
- Dawkins Guy
- Dawson Chris
- De Bolla Alan R
- Dearnaley David P
- Desai Ken M
- Deutsch George P
- Dick John
- Dickinson Andrew J
- Dickson Jeanette
- Dinneen Michael
- Dixit Sanjay
- Dobbs H. Jane
- Doble Andrew
- Dodds David
- Doherty Alan
- Donaldson P
- Donovan Jenny L
- Douglas S. Fiona
- Drake
- Duchesne Gill M
- Duffy Peter
- Dunn Michael
- Dunsmuir W. D
- Durkan Garrett
- Easton Douglas F
- Eccles Diana
- Eden C. D
- Eeles Rosalind A
- El-Modir A
- Elkabir Jeremy
- Elliott Emma
- Ellis B. W
- Ellis R
- Elves Andrew W. S
- Elwell Christine
- Emberton Mark
- Emmerson Louise
- English Dallas R
- Errington R. D
- Evans D. Gareth
- Falconer Alison
- Fawcett Derek
- Featherston C
- Feggetter Jeremy
- Ferguson C
- Fermont D
- Ferro Michael
- Fletcher Matthew
- Folkes A
- Ford Trevor F
- Frim Olivera
- Gallegos Christopher
- Gelister James S
- George Anne
- Gibbs Stephanie
- Gilbert Hugh
- Giles Graham G
- Gillatt David
- Glaholm John
- Glass Jonathan M
- Glenister James
- Goode Thomas D
- Gordon E. M
- Gower Richard L
- Graham John
- Green Damian
- Greenland Jonathan
- Grieve Robert
- Griffiths Thomas R. L
- Gurun Riza Murat
- Guy Michelle
- Guy Peter J
- Hall Amanda L
- Hamdy F. C
- Hamilton C
- Hammonds John
- Hampson S. J
- Hanbury Damien C
- Hardman P. D. John
- Harland Stephen J
- Harney John M
- Harper Peter
- Harrison G. S. M
- Harriss D. R
- Harvey-Hills N
- Hawkyard Simon
- Heath Catherine M
- Hehir Michael
- Hendry David
- Henley Mike
- Herbert Pippa
- Hickish Tamas
- Hindmarsh John R
- Ho Edwin T. S
- Hodgson Shirley
- Holden David
- Holding Peter
- Hollins Graham W
- Holmes Simon A. V
- Hopper John L
- Horwich Alan
- Hoskin Peter
- Howell Graham P
- Howson Joanne
- Hrouda D
- Huddart Robert
- Hudson Liz
- Hughes Michael
- Hughes Owen
- Hughes Rob
- Humber Caroline
- Iacovou John W
- Ibrahim A
- Inglis John A
- Irving Stuart
- Irwin C
- Izatt Louise
- Izegbu Victor
- James Michael J
- James Michael J
- James R. Lester
- Javle Pradip
- Jenkins P
- Jhavar Sameer
- Jones Chris R
- Jones David A
- Jones Gareth
- Jones Mandy
- Joss Shelagh
- Kaisary Amir
- Karim O
- Karp Stephen J
- Keeley F. X
- Kelkar Anand R
- Kelleher J. P
- Kenwrick Sue
- Khan F
- Khoo Vincent
- Kirby Roger S
- Kirk David
- Kirkbride Peter
- Kirollos Magdi M
- Kockelbergh Roger
- Koreich O
- Kote-Jarai Zsofia
- Kourah Mohamed
- Kulkarni Ravi
- Kumar M
- Kunkler Ian H
- Kynaston Howard
- Laing Robert
- Lalloo Fiona
- Lancashire M
- Langley Stephen E. M
- Laniado Marc
- Larner T. R
- Lau Maurice W
- Lawrence W. T
- Lawson Anne
- Le Roux Pieter J
- Leader Mary
- Lee A
- Lee J. O
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- Lemburger R. John
- Lennon Teresa
- Leone Priscilla
- Leongamornlert Daniel A
- Lester Jason
- Leung Hing
- Lewis D. Christopher
- Lewis J
- Liston Thomas
- Livsey Jacqueline
- Lloyd S
- Locke Imogen
- Lodge Richard
- Logue John
- Longmuir Mark
- Lophatananon Artitaya
- Lucas Malcolm G
- Luscombe C. J
- Lydon Anna
- Lynch Michael
- Lyons Norma
- MacDermott James P. A
- Macdonagh Ruaraidh P
- Maher E. R
- Mahmood Rana
- Mair Graeme H. M
- Malone Peter R
- Mark I
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- Matenhelia Shyam
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- McFarlane Jonathan
- McGrath John
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- Mitra Anita
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- Mokete Moeketsi
- Money-Kyrle Julian
- Montgomery Bruce
- Moody Hilary
- Morley Roland
- Morris Sean B
- Morrison Jonathan
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- Mort Diana
- Mostafid Amir H
- Motiwala Hanif
- Mufti Gulzar
- Muir Gordon
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- Mumtaz Faiz
- Murphy Michael
- Murray Alexandra
- Murray Keith W
- Murrell Shirley
- Muthukumar D
- Naerger Harry
- Namasivayam Siva
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- Neilson Donald
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- Oakley Neil
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- Pantelides Michalakis L
- Parikh Omi
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- Parker Christopher C
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- Parys Bohdan T
- Pascoe Sarah
- Patel Anup
- Patterson Helen
- Payne Heather
- Peake David
- Pedley I
- Pengelly A
- Peracha A. M
- Perry Matthew
- Persad Raj
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- Pigott Katharine
- Plail R
- Plowman P. Nicholas
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- Pope A. J
- Popert Rick
- Porter Tim
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- Prasad Krishna
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- Prescott Stephen
- Protheroe Andrew
- Qureshi Khaver N
- Ragavan Narasimhan
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- Rowe Edward
- Rowley Kathryn
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- Srihari Narayana N
- Srinivasan
- Sriram Rajagopalan
- Stewart D
- Stockdale Andrew
- Stott Mark A
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- Strachan John R
- Subramonian K
- Sugden Elaine
- Sundar Santhanam
- Sundaram S. K
- Suresh Gokarakonda
- Susnerwala Shabbir
- Swami Kuchibhotla S
- Syndikus Isabel
- Tahir Saad
- Taylor John W
- Terry T
- Thomas Robert J
- Thomas Stephen A
- Thompson Alan
- Thompson Pauline
- Thomson Alastair H
- Thurston A
- Tilsley Owen
- Tindall Stuart F
- Tong
- Trembath Richard C
- Tulloch David N
- Tweedle James
- Tymrakiewicz Malgorzata
- Tyrell C. J
- Urwin Graeme H
- Van As Nicholas
- Vesey Sean
- Violet John
- Virdi Jaspal
- Waite Katherine
- Walker E. M
- Walker Roger
- Wallace David M. A
- Watkin Nicholas A
- Watson M. E
- Waxman J. H
- Waymont Brian
- Weaver Andrew
- Webb Ralph, J
- Wedderburn Andrew
- Wells Paula
- Wemyss-Holden G. D
- Weston P. M. T
- Wheatley Duncan
- Whelan P
- Whillis D
- Wiles Vicki
- Wilkins Marie
- Wilkinson Rosemary A
- Williams John H
- Williams Simon
- Willis Michael
- Wilson J. R
- Wilson Richard
- Wise Marcus
- Woodhams Simon
- Woodhouse C
- Woolfenden K. A
- Worlding Jane
- Wright Mark
- Wylie James P
- Wynne Chris
- Zang Angelika
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2009
- Field of study
Previous studies have identified multiple loci on 8q24 associated with prostate cancer risk. We performed a comprehensive analysis of SNP associations across 8q24 by genotyping tag SNPs in 5,504 prostate cancer cases and 5,834 controls. We confirmed associations at three previously reported loci and identified additional loci in two other linkage disequilibrium blocks (rs1006908: per-allele OR = 0.87, P = 7.9 x 10(-8); rs620861: OR = 0.90, P = 4.8 x 10(-8)). Eight SNPs in five linkage disequilibrium blocks were independently associated with prostate cancer susceptibility
Identification of seven new prostate cancer susceptibility loci through a genome-wide association study
- Author
- Abrams Paul H
- Adamson Andrew
- Adeyoju A
- Afzal N
- Ahiaku Ernest K. N
- Ahmed Munir
- Aitken Joanne
- Al Olama Ali Amin
- Al-Samerraie Dr
- Alcock Christopher
- Anderson John
- Andrews Henry
- Andrews Steven
- Anjum Iqbal
- Anson Ken
- Apakama Ike
- Aparcia F
- Archbold J. A. A
- Ardern-Jones Audrey T
- Arrand John
- Ash D
- Ashford Richard F. U
- Auvinen Anssi
- Badenoch David
- Bagnato Melisa
- Bahl Amit
- Bailey Karen
- Bailey M. J
- Ball Andrew J
- Bancroft E
- Banerjee G
- Banks Annette
- Barber Jim
- Barber N
- Baria Dr
- Barnes Douglas G
- Barrett Sandra
- Barwell Julian
- Basu Pradip
- Bates Christopher A
- Batra Jyotsna
- Bax N. A
- Baxter-Smith D
- Beacock Christopher
- Beaney Ronald P
- Beard Ralph
- Beck Rupert
- Beese Gail
- Beesley Sharon
- Belcheva Olga
- Bellringer James
- Benson Richard
- Bhatt R. I
- Biedermann Cédric
- Bieri Sabine
- Birch Brian
- Birtle Alison
- Bishop M
- Biyani C. Shekhar
- Blacklock A. R. E
- Blades Rosemary
- Blizzard Leigh
- Bloomfield David J
- Bollina Prasad
- Bonnington Sue
- Booth C. M
- Bose Pradeep
- Bottomley David
- Boucher Nigel R
- Bower Mark
- Bowsher W. G
- Boyd P. J. R
- Bradley Sita Ann
- Bramble F. James
- Bremer Michael
- Brewster Simon F
- Briggs Tim
- Brock Cathryn
- Brock Sue
- Brough Richard
- Brown Paul M
- Brown Richard
- Brown Stephen
- Browning Tony J
- Brugger Margot
- Butorac Kate
- Butterworth Paul C
- Cahill D
- Callaghan P. S
- Calman Frances
- Campbell Alister
- Cannon-Albright Lisa
- Cao Guangwen
- Carnell Dawn M
- Carr T. W
- Carter Adam C
- Carter Charles J. M
- Carter Simon
- Castle Bruce M
- Chadwick David
- Chakraborti P
- Challis David
- Chambers Suzanne
- Chang Wen-Jun
- Chappuis Pierre O
- Charig C
- Chetiyawardana Anula D
- Chilton Christopher
- Chinegwundoh F. I
- Chong Irene
- Chow Wai-Man
- Christmas Tim
- Christova Svetlana
- Churn Mark J
- Clarke Noel W
- Clements Judith
- Coe M
- Cohen N. P
- Coker C
- Cole David J
- Cole O
- Cole Trevor
- Collins Gerald
- Collinson Matthew
- Conn I
- Connell C
- Cooke Peter
- Coombs L
- Coomes Margerie
- Cooney Kathleen A
- Cooper Colin S
- Cooper Debbie
- Copland Robert F
- Cornaby Andrew J
- Cornford P. A
- Corolis Mr
- Corr John
- Corral Roman
- Costello C. B
- Cowan Richard
- Cox Angela
- Cox Robert
- Coyle C
- Crisp John C
- Cruger Dorthe
- Crundwell Malcolm
- Cummings Mr
- Cunningham Julie
- Dahar Nazeer
- Daruwala Pallon
- Datta Shibendra
- Davidson S
- Davies Joseph
- Davis Michael
- Davison Owen W
- Dawkins Guy
- Dawson Chris
- De Bolla Alan R
- Dearnaley David P
- Defabiani Nicolas
- Desai Ken M
- Deutsch George P
- Dick John
- Dickinson Andrew J
- Dickinson Joanne L
- Dickson Jeanette
- Dikov Tihomir
- Dinneen Michael
- Dixit Sanjay
- Dobbs H. Jane
- Doble Andrew
- Dodds David
- Dodova Rumjana
- Doherty Alan
- Donaldson P
- Donovan Jenny L
- Dork Thilo
- Douglas S. Fiona
- Drake Mr
- Dubrowinskaja Natalia
- Duchesne Gill M
- Duffy Peter
- Dunn Michael
- Dunsmuir W. D
- Durkan Garrett
- Easton Douglas F
- Eccles Diana
- Eden C. D
- Edwards Stephen M
- Eeles Rosalind A
- El-Modir A
- Elkabir Jeremy
- Elliott Emma
- Ellis B. W
- Ellis R
- Elves Andrew W. S
- Elwell Christine
- Emberton Mark
- Emmerson Louise
- English Dallas R
- Errington R. D
- Evans D. Gareth
- Falconer Alison
- Farnham Jim
- Fawcett Derek
- Featherston C
- Feggetter Jeremy
- Ferguson C
- Ferguson Megan
- Fermont D
- Ferro Michael
- Fisher Cyril
- Fitzgerald Liesel M
- Flanagan Louise
- Fletcher Matthew
- Folkes A
- Foote Simon
- Ford Trevor F
- Foulkes William D
- Frim Olivera
- Gallagher Stephen
- Gallegos Christopher
- Gardiner R. A. (Frank)
- Gelister James S
- George Anne
- Gibbs Stephanie
- Gilbert Hugh
- Giles Graham G
- Gillatt David
- Girardet Christophe
- Glaholm John
- Glass Jonathan M
- Glenister James
- Goode Thomas D
- Gordon E. M
- Gower Richard L
- Graham John
- Green Damian
- Greenland Jonathan
- Grieve Robert
- Griffiths Thomas R. L
- Gurun Riza Murat
- Guy Michelle
- Guy Peter J
- Haiman Christopher A
- Hall Amanda L
- Hamdy Freddie C
- Hamel Nancy
- Hamilton C
- Hammonds John
- Hampson S. J
- Hanbury Damien C
- Hardman P. D. John
- Harland Stephen J
- Harney John M
- Harper Peter
- Harrison G. S. M
- Harriss D. R
- Harvey-Hills N
- Hawkyard Simon
- Heath Catherine M
- Hehir Michael
- Henderson Brian E
- Hendry David
- Henley Mike
- Herbert Pippa
- Herkommer Kathleen
- Hickish Tamas
- Hillemanns Peter
- Hindmarsh John R
- Hinze Kimberly
- Ho Edwin T. S
- Hodgson Shirley
- Holden David
- Holding Peter
- Hollins Graham W
- Holmes Simon A. V
- Hopper John L
- Horwich Alan
- Hoskin Peter
- Hou Jian-Guo
- Howell Graham P
- Howson Joanne
- Hrouda D
- Huddart Robert A
- Hudson Liz
- Hughes Michael
- Hughes Owen
- Hughes Rob
- Humber Caroline
- Hutter Pierre
- Iacovou John W
- Ibrahim A
- Ingles Sue A
- Inglis John A
- Irving Stuart
- Irwin C
- Isotalo Jarkko
- Izatt Louise
- Izegbu Victor
- James Michael J
- James N
- James R. Lester
- Jameson Charles
- Javle Pradip
- Jenkins P
- Jhavar Sameer
- John Esther M
- Johnson Emilie K
- Jones Chris R
- Jones David A
- Jones Gareth
- Jones Mandy
- Joshi Amit D
- Joss Shelagh
- Kachakova Darina
- Kaisary Amir
- Kaneva Radka
- Karim O
- Karp Stephen J
- Karstens Johann H
- Karyadi Danielle M
- Kedda Mary Anne
- Keeley F. X
- Kelham Penelope
- Kelkar Anand R
- Kelleher J. P
- Kenwrick Sue
- Khan F
- Khan Humera
- Khoo Vincent S
- Kirby Roger S
- Kirk David
- Kirkbride Peter
- Kirollos Magdi M
- Kockelbergh Roger
- Kolonel Laurence N
- Konzelmann Isabelle
- Koopmeiners Joseph S
- Koreich O
- Kotar Kimberley
- Kote-Jarai Zsofia
- Kourah Mohamed
- Kuczyk Markus
- Kuefer Rainer
- Kulkarni Ravi
- Kumar M
- Kunkler Ian H
- Kwon Erika M
- Kynaston Howard
- Laing Robert
- Lalloo Fiona
- Lancashire M
- Lange Ethan M
- Langley Stephen E. M
- Laniado Marc
- Larner T. R
- Lau Maurice W
- Lawrence W. T
- Lawson Anne
- Le Marchand Loic
- Le Roux Pieter J
- Leader Mary
- Lee A
- Lee J. O
- Lee L
- Lemburger R .John
- Lennon Teresa
- Leone Priscilla
- Leongamornlert Daniel A
- Lester Jason
- Leung Hing
- Lewis D. Christopher
- Lewis J
- Lewis Sarah J
- Liston Thomas
- Liu Jo-Fen
- Livsey Jacqueline
- Lloyd S
- Locke Imogen
- Lodge Richard
- Logue John
- Longmuir Mark
- Lophatananon Artitaya
- Lose Felicity
- Lu Yong-Jie
- Lucas Malcolm G
- Luedeke Manuel
- Luscombe C. J
- Lydon Anna
- Lynch Michael
- Lyons Norma
- MacDermott James P. A
- Macdonagh Ruaraidh P
- Machtens Stefan
- Maher E. R
- Mahmood Rana
- Maier Christiane
- Mair Graeme H. M
- Malone Peter R
- Mark I
- Marsden Gemma
- Mason M. D
- Mason Robert
- Matenhelia Shyam
- Matikainen Mika
- Matthews Philip N
- Mattila Henna
- McArdle John
- McBride Donna
- McDonnell Shannon K
- McFarlane Jonathan
- McGrath John
- McInerney Paul
- McIntosh Gregor
- McKay James
- McKinna F
- McLaren Duncan
- McMenemin Rhona
- McNicholas T. A
- McWhirter Rebekah
- Meddings Robert N
- Mee A. David
- Meier Marie-Mathilde
- Memon Mr
- Menzes Pravin
- Meyer Andreas
- Mills Robert
- Mitchell S
- Mitev Vanio
- Mithal Natasha
- Mitkova Atanaska
- Mitra Anita
- Mobb Gillian E
- Moffat Leslie E. F
- Mokete Moeketsi
- Money-Kyrle Julian
- Montgomery Bruce
- Montie James E
- Moody Hilary
- Morley Roland
- Morris Sean B
- Morrison Jonathan
- Morrison Patrick
- Mort Diana
- Mostafid Amir H
- Motiwala Hanif
- Mufti Gulzar
- Muir Gordon
- Muir Kenneth
- Mumtaz Faiz
- Murphy Michael
- Murray Alexandra
- Murray Keith W
- Murrell Shirley
- Muthukumar D
- Naerger Harry
- Namasivayam Siva
- Nargund Vinod
- Nawrocki Jan
- Neal David E
- Neilson Donald
- Nelson Colleen
- Nethersell A
- Newman Beth
- Newman Hugh
- Newton R
- Nicol David
- Nikolov Momchil
- O'Boyle P. J
- O'Brien J
- O'Brien Lynne T
- O'Brien Tim S
- O'Donoghue E
- O'Donoghue Neil
- O'Mara Tracy
- O'Reilly P
- O'Rourke J. S
- O'Sullivan Joe
- Oakley Neil
- Ogden Chris
- Ohja Hemant
- Oliver Tim
- Osborn David
- Ostler Peter
- Ostrander Elaine A
- Page Elizabeth C
- Paiss Thomas
- Pakkanen Sanna
- Palfrey Edward
- Panades Miguel
- Pancharatnam M
- Pantelides Michalakis L
- Parikh Omi
- Park Hyun Y
- Park Jong Y
- Parker Christopher C
- Parker Christopher H
- Parys Bohdan T
- Pascoe Sarah
- Patel Anup
- Patterson Briony
- Patterson Helen
- Payne Heather
- Peake David
- Pedersen John
- Pedley I
- Pengelly A
- Peracha A. M
- Perry Matthew
- Persad Raj
- Peter Hans-Ulrich
- Philp N. H
- Philp T
- Pigott Katharine
- Plail R
- Plowman P. Nicholas
- Pocock Richard D
- Polanowski Andrea
- Pope A. J
- Popert Rick
- Popov Elenko
- Porter Tim
- Pow-Sang Julio
- Powell Christopher
- Powell Philip
- Prasad Krishna
- Prejbisz J. W
- Prescott Stephen
- Protheroe Andrew
- Qureshi Khaver N
- Radein Selina
- Ragavan Narasimhan
- Rankin Julia
- Rao Y
- Ravi Ramachandran
- Ray Anna M
- Read Graham
- Rebbeck Timothy R
- Reddy Paul J
- Rimington Peter R
- Rincon Maria
- Roberts J. Trevor
- Robertson Andrew
- Robinson Angus
- Robinson Anne C
- Robinson Lee Q
- Rogers P. B
- Rowbotham Carl
- Rowe Edward
- Rowley Kathryn
- Rundle John
- Russell John M
- Ryan P. G
- Saggar Anand K
- Samanci Ali
- Saunders Edward J
- Sawyer Emma J
- Saxby M. F
- Schaid Daniel
- Schleutker Johanna
- Schwaibold Hartwig
- Scoble John E
- Scrase Christopher
- Sellers Thomas A
- Sells Henry
- Serth Jürgen
- Sethia Krishna K
- Severi Gianluca
- Shah Nihil
- Shahabi Ahva
- Shanley Sue
- Sharma Neerah K
- Sheehan Denise J
- Sherwin Elizabeth
- Shum L
- Siltanen Sanna
- Simcock R
- Singh Pravin
- Siva M
- Slavov Chavdar
- Smark Heidi
- Smith Charmaine
- Smith James
- Smith Michael F
- Sokal Michael
- Sole Graham M
- Southey Melissa C
- Spangler Elaine
- Speakman Mark J
- Spurdle Amanda
- Sreenivasan Thiagarajan
- Srihari Narayanan N
- Srinivasan Mr
- Sriram Rajagopalan
- Stalder Michèle
- Stanford Janet L
- Stankovich James
- Stefflova Klara
- Stenman Ulf-HÃ¥kan
- Stern Mariana C
- Stewart D
- Stockdale Andrew
- Stott Mark A
- Stower M. J
- Strachan John R
- Subramonian K
- Sugden Elaine
- Sundar Santhanam
- Sundaram S. K
- Suresh Gokarakonda
- Surowy Harald
- Susnerwala Shabbir
- Swami Kuchibhotla S
- Syndikus Isabel
- Tahir Saad
- Tammela Teuvo L
- Taylor John W
- Terry T
- Thibodeau Stephen N
- Thomas Robert J
- Thomas Stephen A
- Thompson Alan
- Thompson Pauline
- Thomson Alastair H
- Thomson Russell
- Thurston A
- Tilsley Owen
- Tindall Stuart F
- Tong Dr
- Trembath Richard C
- Tulloch David N
- Tweedle James
- Tymrakiewicz Malgorzata
- Tyrell C. J
- Urwin Graeme H
- Van As Nicholas
- VandenBergh Patrica
- Vesey Sean
- Violet John
- Virdi Jaspal
- Vlahova Aleksandrina
- Vogel Walther
- von Klot Christoph
- Wahlfors Tiina
- Waite Katherine
- Walker Amy
- Walker E. M
- Walker Roger
- Wallace David M. A
- Wang Liang
- Watkin Nicholas A
- Watson M. E
- Waxman J. H
- Waymont Brian
- Weaver Andrew
- Webb Ralph J
- Weber Bärbel
- Wedderburn Andrew
- Wells Paula
- Wemyss-Holden G. D
- Weston P. M. T
- Wheatley Duncan
- Whelan P
- Whillis D
- Wiest Irina
- Wiles Vicki
- Wilkins Marie
- Wilkinson Rosemary A
- Williams John H
- Williams Simon
- Willis Michael
- Wilson J. R
- Wilson Richard
- Wise Marcus
- Woodhams Simon
- Woodhouse Christopher J
- Woolfenden K. A
- Worlding Jane
- Wright Mark
- Wylie James P
- Wynne Chris
- Xu Dan-Feng
- Xu Xing-Xing
- Yaxley John
- Zachariah Babu
- Zakariah Babu
- Zang Angelika
- Zeegers Maurice
- Zeigler-Johnson Charnita
- Zhang Hong-Wei
- Zuhlke Kimberly A
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2009
- Field of study
Prostate cancer (PrCa) is the most frequently diagnosed male cancer in developed countries. To identify common PrCa susceptibility alleles, we have previously conducted a genome-wide association study in which 541, 129 SNPs were genotyped in 1,854 PrCa cases with clinically detected disease and 1,894 controls. We have now evaluated promising associations in a second stage, in which we genotyped 43,671 SNPs in 3,650 PrCa cases and 3,940 controls, and a third stage, involving an additional 16,229 cases and 14,821 controls from 21 studies. In addition to previously identified loci, we identified a further seven new prostate cancer susceptibility loci on chromosomes 2, 4, 8, 11, and 22 (P=1.6×10−8 to P=2.7×10−33)