An improved limit on the neutrino mass with CMB and redshift-dependent halo bias-mass relations from SDSS, DEEP2, and Lyman-Break Galaxies

We use measurements of luminosity-dependent galaxy bias at several different redshifts, SDSS at $z=0.05$, DEEP2 at $z=1$ and LBGs at $z=3.8$, combined with WMAP five-year cosmic microwave background anisotropy data and SDSS Red Luminous Galaxy survey three-dimensional clustering power spectrum to put constraints on cosmological parameters. Fitting this combined dataset, we show that the luminosity-dependent bias data that probe the relation between halo bias and halo mass and its redshift evolution are very sensitive to sum of the neutrino masses: in particular we obtain the upper limit of $\sum m_{\nu}<0.28$eV at the 95% confidence level for a $\Lambda CDM + m_{\nu}$ model, with a $\sigma_8$ equal to $\sigma_8=0.759\pm0.025$ (1$\sigma$). When we allow the dark energy equation of state parameter $w$ to vary we find $w=-1.30\pm0.19$ for a general $wCDM+m_{\nu}$ model with the 95% confidence level upper limit on the neutrino masses at $\sum m_{\nu}<0.59$eV. The constraint on the dark energy equation of state further improves to $w=-1.125\pm0.092$ when using also ACBAR and supernovae Union data, in addition to above, with a prior on the Hubble constant from the Hubble Space Telescope.Comment: 9 pages, 6 figures, submitted to PR

Exact relativistic beta decay endpoint spectrum

The exact relativistic form for the beta decay endpoint spectrum is derived and presented in a simple factorized form. We show that our exact formula can be well approximated to yield the endpoint form used in the fit method of the KATRIN collaboration. We also discuss the three neutrino case and how information from neutrino oscillation experiments may be useful in analyzing future beta decay endpoint experiments.Comment: 12 pages, 3 figure

APDs as Single-Photon Detectors for Visible and Near-Infrared Wavelenghts down to Hz Rates

For the SPECTRAP experiment at GSI, Germany, detectors with Single-Photon counting capability in the visible and near-infrared regime are required. For the wavelength region up to 1100 nm we investigate the performance of 2x2 mm^2 avalanche photo diodes (APDs) of type S0223 manufactured by Radiation Monitoring Devices. To minimize thermal noise, the APDs are cooled to approximately -170 deg. C using liquid nitrogen. By operating the diodes close to the breakdown voltage it is possible to achieve relative gains in excess of 2x10^4. Custom-made low noise preamplifiers are used to read out the devices. The measurements presented in this paper have been obtained at a relative gain of 2.2x10^4. At a discriminator threshold of 6 mV the resulting dark count rate is in the region of 230/s. With these settings the studied APDs are able to detect single photons at 628 nm wavelength with a photo detection efficiency of (67+-7)%. Measurements at 1020 nm wavelength have been performed using the attenuated output of a grating spectrograph with a light bulb as photon source. With this setup the photo detection efficiency at 1020 nm has been determined to be (13+-3)%, again at a threshold of 6 mV.Comment: 14 pages, 9 figures, submitted to Journal of Instrumentatio

APDs as Single-Photon Detectors for Visible and Near-Infrared Wavelenghts down to Hz Rates

For the SPECTRAP experiment at GSI, Germany, detectors with Single-Photon counting capability in the visible and near-infrared regime are required. For the wavelength region up to 1100 nm we investigate the performance of 2x2 mm^2 avalanche photo diodes (APDs) of type S0223 manufactured by Radiation Monitoring Devices. To minimize thermal noise, the APDs are cooled to approximately -170 deg. C using liquid nitrogen. By operating the diodes close to the breakdown voltage it is possible to achieve relative gains in excess of 2x10^4. Custom-made low noise preamplifiers are used to read out the devices. The measurements presented in this paper have been obtained at a relative gain of 2.2x10^4. At a discriminator threshold of 6 mV the resulting dark count rate is in the region of 230/s. With these settings the studied APDs are able to detect single photons at 628 nm wavelength with a photo detection efficiency of (67+-7)%. Measurements at 1020 nm wavelength have been performed using the attenuated output of a grating spectrograph with a light bulb as photon source. With this setup the photo detection efficiency at 1020 nm has been determined to be (13+-3)%, again at a threshold of 6 mV.Comment: 14 pages, 9 figures, submitted to Journal of Instrumentatio

APDs as Single-Photon Detectors for Visible and Near-Infrared Wavelenghts down to Hz Rates

For the SPECTRAP experiment at GSI, Germany, detectors with Single-Photon counting capability in the visible and near-infrared regime are required. For the wavelength region up to 1100 nm we investigate the performance of 2x2 mm^2 avalanche photo diodes (APDs) of type S0223 manufactured by Radiation Monitoring Devices. To minimize thermal noise, the APDs are cooled to approximately -170 deg. C using liquid nitrogen. By operating the diodes close to the breakdown voltage it is possible to achieve relative gains in excess of 2x10^4. Custom-made low noise preamplifiers are used to read out the devices. The measurements presented in this paper have been obtained at a relative gain of 2.2x10^4. At a discriminator threshold of 6 mV the resulting dark count rate is in the region of 230/s. With these settings the studied APDs are able to detect single photons at 628 nm wavelength with a photo detection efficiency of (67+-7)%. Measurements at 1020 nm wavelength have been performed using the attenuated output of a grating spectrograph with a light bulb as photon source. With this setup the photo detection efficiency at 1020 nm has been determined to be (13+-3)%, again at a threshold of 6 mV.Comment: 14 pages, 9 figures, submitted to Journal of Instrumentatio

Precision high voltage divider for the KATRIN experiment

The Karlsruhe Tritium Neutrino Experiment (KATRIN) aims to determine the absolute mass of the electron antineutrino from a precise measurement of the tritium beta-spectrum near its endpoint at 18.6 keV with a sensitivity of 0.2 eV. KATRIN uses an electrostatic retardation spectrometer of MAC-E filter type for which it is crucial to monitor high voltages of up to 35 kV with a precision and long-term stability at the ppm level. Since devices capable of this precision are not commercially available, a new high voltage divider for direct voltages of up to 35 kV has been designed, following the new concept of the standard divider for direct voltages of up to 100 kV developed at the Physikalisch-Technische Bundesanstalt (PTB). The electrical and mechanical design of the divider, the screening procedure for the selection of the precision resistors, and the results of the investigation and calibration at PTB are reported here. During the latter, uncertainties at the low ppm level have been deduced for the new divider, thus qualifying it for the precision measurements of the KATRIN experiment.Comment: 22 pages, 12 figure

Repetitive myocardial ischemia promotes coronary growth in the adult mammalian heart

BACKGROUND: Coronary artery disease and ischemic cardiomyopathy represent the leading cause of heart failure and continue to grow at exponential rates. Despite widespread availability of coronary bypass surgery and percutaneous coronary intervention, subsequent ischemic events and progression to heart failure continue to be common occurrences. Previous studies have shown that a subgroup of patients develop collateral blood vessels that serve to connect patent and occluded arteries and restore perfusion to ischemic territories. The presence of coronary collaterals has been correlated with improved clinical outcomes; however, the molecular mechanisms governing this process remain largely unknown. METHODS AND RESULTS: To date, no mouse models of coronary arterial growth have been described. Using a closed‐chest model of myocardial ischemia, we have demonstrated that brief episodes of repetitive ischemia are sufficient to promote the growth of both large coronary arteries and the microvasculature. Induction of large coronary artery and microvascular growth resulted in improvements in myocardial perfusion after prolonged ischemia and protected from subsequent myocardial infarction. We further show that repetitive ischemia did not lead to increased expression of classic proangiogenic factors but instead resulted in activation of the innate immune system and recruitment of macrophages to growing blood vessels. CONCLUSIONS: These studies describe a novel model of coronary angiogenesis and implicate the cardiac macrophage as a potential mediator of ischemia‐driven coronary growth

Improved treatment of the T2T_2 molecular final-states uncertainties for the KATRIN neutrino-mass measurement

The KArlsruhe TRItium Neutrino experiment (KATRIN) aims to determine the effective mass of the electron antineutrino via a high-precision measurement of the tritium beta-decay spectrum in its end-point region. The target neutrino-mass sensitivity of 0.2 eV / c^2 at 90% C.L. can only be achieved in the case of high statistics and a good control of the systematic uncertainties. One key systematic effect originates from the calculation of the molecular final states of T_2 beta decay. In the first neutrino-mass analyses of KATRIN the contribution of the uncertainty of the molecular final-states distribution (FSD) was estimated via a conservative phenomenological approach to be 0.02 eV^2 / c^4. In this paper a new procedure is presented for estimating the FSD-related uncertainties by considering the details of the final-states calculation, i.e. the uncertainties of constants, parameters, and functions used in the calculation as well as its convergence itself as a function of the basis-set size used in expanding the molecular wave functions. The calculated uncertainties are directly propagated into the experimental observable, the squared neutrino mass m_nu^2. With the new procedure the FSD-related uncertainty is constrained to 0.0013 eV^2 / c^4, for the experimental conditions of the first KATRIN measurement campaign