313 research outputs found
Ariel - Volume 4 Number 4
Editors
David A. Jacoby
Eugenia Miller
Tom Williams
Associate Editors
Paul Bialas
Terry Burt
Michael Leo
Gail Tenikat
Editor Emeritus and Business Manager
Richard J. Bonnano
Movie Editor
Robert Breckenridge
Staff
Richard Blutstein
Mary F. Buechler
Meg Brunt
Steve Glinks
Len Grasman
Alice M. Johnson
J.D. Kanofsky
Tom Lehman
Dave Mayer
Bernie Odd
Determination of uromodulin in human urine: influence of storage and processing
Background Uromodulin (Tamm-Horsfall protein) is the most abundant protein excreted in the urine under physiological conditions. It is exclusively produced in the kidney and secreted into the urine via proteolytic cleavage. The involvement of UMOD, the gene that encodes uromodulin, in rare autosomal dominant diseases, and its robust genome-wide association with the risk of chronic kidney disease suggest that the level of uromodulin in urine could represent a critical biomarker for kidney function. The structure of uromodulin is complex, with multiple disulfide bonds and typical domains of extracellular proteins. Methods Thus far, the conditions influencing stability and measurement of uromodulin in human urine have not been systematically investigated, giving inconsistent results. In this study, we used a robust, in-house ELISA to characterize the conditions of sampling and storage necessary to provide a faithful dosage of uromodulin in the urine. Results The levels of uromodulin in human urine were significantly affected by centrifugation and vortexing, as well as by the conditions and duration of storage. Conclusions These results validate a simple, low-cost ELISA and document the optimal conditions of processing and storage for measuring uromodulin in human urin
Campus Vol 1 N 2
Wise, Thea. Variation On A Theme . Prose. 2.
Findeisen, Bob. A Fine Art . Prose. 3.; Anonymous. Winter Moments On Campus . Picture. 4.
Anonymous. Transient Types . Cartoon. 6.
Smith, Winifred and Gloria Weber. A Sweetheart Serenade . Prose. 8.
Anonymous. High Man on A Bed Post . Prose. 9.
Thomas, John G. Campus Kaleidoscope . Prose. 10.
Anonymous. Fraternities: The Way We See \u27Em . 12.
Meyer, Marilynn. Study Time At East . Poem. 14.
Meyer, Marilynn. IF . Poem. 14.
Leonard, Judy. Magic Music . Poem. 14.
Teachnor, Janet. Weighty Words . Prose. 17
Colorado Native Plant Society Newsletter, Vol. 7 No. 2, March-April 1983
https://epublications.regis.edu/aquilegia/1166/thumbnail.jp
Colorado Native Plant Society Newsletter, Vol. 6 No. 3, July-September 1982
https://epublications.regis.edu/aquilegia/1162/thumbnail.jp
Aquilegia, Vol. 34 No. 5, Winter 2010, Newsletter of the Colorado Native Plant Society
https://epublications.regis.edu/aquilegia/1135/thumbnail.jp
Colorado Native Plant Society Newsletter, Vol. 6 No. 4, October-December 1982
https://epublications.regis.edu/aquilegia/1163/thumbnail.jp
A MediaWiki implementation of single-access keys
Design principles, features, and data exchange options of an
open source implementation of single access keys for the collaborative
MediaWiki platform are presented
The Ursinus Weekly, October 25, 1948
Ranung and Klein to offer musicale; program to feature folk songs, arias • Fowler, two profs give party views in opening forum • Campus election slated for Wednesday; enthusiasm runs high among students • \u27Y\u27 committees plan numerous activities • Sororities to begin sophomore rushing • Week-end cheerful despite grid loss • Luncheons attended by many ex-coeds • Curtain Club plans show for November presentation • Officers of IRC to attend conference at Penn State • Frosh bear fund reaches $28 in drive to buy new costume • Frosh hold annual banquet with Gene Glick as guest • Chem society begins year; executive committee voted • Ruby will conduct raffle in new subscription drive • Bachelors number 338 as total vets enrollment reaches 423 • Freshman relates experiences abroad • How to make your room inhabitable • Introducing Steve Arvanitis • Gridders to tackle Staten Island team • JVs held scoreless in Hill soccer tilt • Sam Gary tosses four touchdown aerials as Swarthmore wins old timers\u27 battle 24-7 • Seeders calls team for hoop practice • Co-ed JVs extend undefeated record • Lafayette tramples varsity booters 9-0 • Soccer squad clips alumni booters 4-0 • Varsity tripped 2-0 by hockey alumnae • Hayseed fans shine at junior shindig • WSGA names three women to nominating committee • Cub & Key holds first meeting; dinner in Philadelphia plannedhttps://digitalcommons.ursinus.edu/weekly/1599/thumbnail.jp
Ariel - Volume 4 Number 6
Editors
David A. Jacoby
Eugenia Miller
Tom Williams
Associate Editors
Paul Bialas
Terry Burt
Michael Leo
Gail Tenikat
Editor Emeritus and Business Manager
Richard J. Bonnano
Movie Editor
Robert Breckenridge
Staff
Richard Blutstein
Mary F. Buechler
J.D. Kanofsky
Rocket Weber
David Maye
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