Detection of a Substantial Molecular Gas Reservoir in a brightest cluster galaxy at z = 1.7

We report the detection of CO(2-1) emission coincident with the brightest cluster galaxy (BCG) of the high-redshift galaxy cluster SpARCS1049+56, with the Redshift Search Receiver (RSR) on the Large Millimetre Telescope (LMT). We confirm a spectroscopic redshift for the gas of z = 1.7091+/-0.0004, which is consistent with the systemic redshift of the cluster galaxies of z = 1.709. The line is well-fit by a single component Gaussian with a RSR resolution-corrected FWHM of 569+/-63 km/s. We see no evidence for multiple velocity components in the gas, as might be expected from the multiple image components seen in near-infrared imaging with the Hubble Space Telescope. We measure the integrated flux of the line to be 3.6+/-0.3 Jy km/s and, using alpha_CO = 0.8 Msun (K km s^-1 pc^2)^-1 we estimate a total molecular gas mass of 1.1+/-0.1x10^11 Msun and a M_H2/M_star ~ 0.4. This is the largest gas reservoir detected in a BCG above z > 1 to date. Given the infrared-estimated star formation rate of 860+/-130 Msun/yr, this corresponds to a gas depletion timescale of ~0.1Gyr. We discuss several possible mechanisms for depositing such a large gas reservoir to the cluster center -- e.g., a cooling flow, a major galaxy-galaxy merger or the stripping of gas from several galaxies -- but conclude that these LMT data are not sufficient to differentiate between them.Comment: accepted for publication in ApJ Letter

The Phase Space and Stellar Populations of Cluster Galaxies at z ~ 1: Simultaneous Constraints on the Location and Timescale of Satellite Quenching

We investigate the velocity vs. position phase space of z ~ 1 cluster galaxies using a set of 424 spectroscopic redshifts in 9 clusters drawn from the GCLASS survey. Dividing the galaxy population into three categories: quiescent, star-forming, and poststarburst, we find that these populations have distinct distributions in phase space. Most striking are the poststarburst galaxies, which are commonly found at small clustercentric radii with high clustercentric velocities, and appear to trace a coherent ``ring" in phase space. Using several zoom simulations of clusters we show that the coherent distribution of the poststarbursts can be reasonably well-reproduced using a simple quenching scenario. Specifically, the phase space is best reproduced if satellite quenching occurs on a rapid timescale (0.1 < tau_{Q} < 0.5 Gyr) after galaxies make their first passage of R ~ 0.5R_{200}, a process that takes a total time of ~ 1 Gyr after first infall. We compare this quenching timescale to the timescale implied by the stellar populations of the poststarburst galaxies and find that the poststarburst spectra are well-fit by a rapid quenching (tau_{Q} = 0.4^{+0.3}_{-0.4} Gyr) of a typical star-forming galaxy. The similarity between the quenching timescales derived from these independent indicators is a strong consistency check of the quenching model. Given that the model implies satellite quenching is rapid, and occurs well within R_{200}, this would suggest that ram-pressure stripping of either the hot or cold gas component of galaxies are the most plausible candidates for the physical mechanism. The high cold gas consumption rates at z ~ 1 make it difficult to determine if hot or cold gas stripping is dominant; however, measurements of the redshift evolution of the satellite quenching timescale and location may be capable of distinguishing between the two.Comment: 10 pages, 4 figures, submitted to the Ap

Comprehensive health assessments during de-institutionalization: An observational study

Background: People with intellectual disability (ID) leaving institutions pass through a transition stage that makes them vulnerable to inadequate health care. They enter into community care under general practitioners (GPs) who are often untrained and inexperienced in their needs. Specifically designed health reviews may be of assistance to both them and their new GPs as they go through that phase

“My journey map”: Developing a qualitative approach to mapping young people’s progress in residential rehabilitation

Young people with substance misuse issues are at risk of harm from significant negative health and life events. Contemporary research notes both a historical failure to recognize the unique needs of adolescents, and the ongoing need for dedicated adolescent treatment programs and outcome measures. It is concerning that there is so little literature assessing the quality, availability, and effectiveness of adolescent-focused treatment programs, and no adolescent-specific measurement tools centered on a young person’s progress in residential treatment. This article reports on the process of developing a qualitative approach to mapping progress in treatment over time. The research seeks to develop an approach that captures, at three points in time and from multiple viewpoints, the progress of young people in four residential rehabilitation services located in New South Wales and Western Australia, across several dimensions of the personal and social aspects of life. Our aim is to develop an approach that is accessible to the alcohol and other drug workforce, and that informs the development of a psychometrically robust quantitative measure of progress that is meaningful and useful both to practitioners and to the young people themselves

Galaxy Merger Candidates in High-Redshift Cluster Environments

We compile a sample of spectroscopically- and photometrically-selected cluster galaxies from four high-redshift galaxy clusters ($1.59 < z < 1.71$) from the Spitzer Adaptation of the Red-Sequence Cluster Survey (SpARCS), and a comparison field sample selected from the UKIDSS Deep Survey. Using near-infrared imaging from the \textit{Hubble Space Telescope} we classify potential mergers involving massive ($M_* \geq 3\times 10^{10}\mathrm{M}_\odot$) cluster members by eye, based on morphological properties such as tidal distortions, double nuclei, and projected near neighbors within 20 kpc. With a catalogue of 23 spectroscopic and 32 photometric massive cluster members across the four clusters and 65 spectroscopic and 26 photometric comparable field galaxies, we find that after taking into account contamination from interlopers, $11.0 ^{+7.0}_{-5.6}\%$ of the cluster members are involved in potential mergers, compared to $24.7^{+5.3}_{-4.6}\%$ of the field galaxies. We see no evidence of merger enhancement in the central cluster environment with respect to the field, suggesting that galaxy-galaxy merging is not a stronger source of galaxy evolution in cluster environments compared to the field at these redshifts.Comment: Accepted by Ap

Outcomes in treatment-resistant schizophrenia: symptoms, function and clozapine plasma concentrations

Background: Clozapine is the only medication licenced for treating patients with treatment-refractory schizophrenia. However, there are no evidence-based guidelines as to the optimal plasma level of clozapine to aim for, and their association with clinical and functional outcome. Objective: We assessed the relationship between clinical and functional outcome measures and blood concentrations of clozapine among patients with treatment-refractory psychosis. Methods: Data were reviewed in 82 patients with treatment-refractory psychosis admitted to a specialised tertiary-level service and treated with clozapine. Analysis focussed on the relationship between clozapine and norclozapine plasma concentrations and the patient’s clinical symptoms and functional status. Results: Clinical symptom improvement was positively correlated with norclozapine plasma concentrations and inversely correlated with clozapine to norclozapine plasma concentrations ratio. Clozapine concentrations showed a bimodal association with clinical improvement (peaks around 350 and 660 ng/ml). Clinical symptom improvement correlated with functional outcomes, although there was no significant correlation between the latter and clozapine or norclozapine plasma concentrations. Conclusion: Clozapine treatment was associated with optimal clinical improvement at two different peak plasma concentrations around 350 and 650 ng/ml. Clinical improvement was associated with functional outcome; however, functionality was not directly associated with clozapine concentrations. A subset of patients may require higher clozapine plasma concentrations to achieve clinical improvement

A Kinematic Approach To Assessing Environmental Effects: Star-Forming Galaxies in a z~0.9 SpARCS cluster using Spitzer 24um Observations

We present an infrared study of a z=0.872 cluster, SpARCS J161314+564930, with the primary aim of distinguishing the dynamical histories of spectroscopically confirmed star-forming members to assess the role of cluster environment. We utilize deep MIPS imaging and a mass-limited sample of 85 spectroscopic members to identify 16 24um-bright sources within the cluster, and measure their 24um star formation rates (SFRs) down to ~6 Msolar/year. Based on their line-of-sight velocities and stellar ages, MIPS cluster members appear to be an infalling population that was recently accreted from the field with minimal environmental dependency on their star formation. However, we identify a double-sequenced distribution of star-forming galaxies amongst the members, with one branch exhibiting declining specific SFRs with mass. The members along this sub-main sequence contain spectral features suggestive of passive galaxies. Using caustic diagrams, we kinematically identify these galaxies as a virialized and/or backsplash population. Moreover, we find a mix of dynamical histories at all projected radii, indicating that standard definitions of environment (i.e., radius and density) are contaminated with recently accreted interlopers, which could contribute to a lack of environmental trends for star-forming galaxies. A cleaner narrative of their dynamical past begins to unfold when using a proxy for accretion histories through profiles of constant (r/r_200)x(Delta v/sigma_v); galaxies accreted at earlier times possess lower values of (r/r_200)x(Delta v/sigma_v) with minimal contamination from the distinct infalling population. Therefore, adopting a time-averaged definition for density (as traced by accretion histories) rather than an instantaneous density yields a depressed specific SFR within the dynamical cluster core.Comment: 14 pages, 10 figures, 1 table; accepted for publication in Ap