129 research outputs found

    Aspect-oriented Modeling of Attacks in Automotive Cyber-Physical Systems

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    This paper introduces aspect-oriented modeling (AOM) as a powerful, model-based design technique to assess the secu- rity of Cyber-Physical Systems (CPS). Particularly in safety- critical CPS such as automotive control systems, the pro- tection against malicious design and interaction faults is paramount to guaranteeing correctness and reliable opera- tion. Essentially, attack models are associated with the CPS in an aspect-oriented manner to evaluate the system under attack. This modeling technique requires minimal changes to the model of the CPS. Using application-specic metrics, the designer can gain insights into the behavior of the CPS under attack. Copyright 2014 ACM

    Disease Specific Autoantibodies in Idiopathic Inflammatory Myopathies

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    Idiopathic inflammatory myopathies represent still a diagnostic and therapeutic challenge in different disciplines including neurology, rheumatology, and dermatology. In recent years, the spectrum of idiopathic inflammatory myopathies has been significantly extended and the different manifestations were described in more detail leading to new classification criteria. A major breakthrough has also occurred with respect to new biomarkers especially with the characterization of new autoantibody-antigen systems, which can be separated in myositis specific antibodies and myositis associated antibodies. These markers are detectable in approximately 80% of patients and facilitate not only the diagnostic procedures, but provide also important information on stratification of patients with respect to organ involvement, risk of cancer and overall prognosis of disease. Therefore, it is not only of importance to know the significance of these markers and to be familiar with the optimal diagnostic tests, but also with potential limitations in detection. This article focuses mainly on antibodies which are specific for myositis providing an overview on the targeted antigens, the available detection procedures and clinical association. As major tasks for the near future, the need of an international standardization is discussed for detection methods of autoantibodies in idiopathic inflammatory myopathies. Furthermore, additional investigations are required to improve stratification of patients with idiopathic inflammatory myopathies according to their antibody profile with respect to response to different treatment options

    A review of the evolution of spatio-temporal data types

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    Only the abstract and references were published in the proceedings. There is no full text.The motivation for this presentation is to show current approaches for modelling processes in time and space. Different approaches have taken place to extend existing RDBMS to spatio-temporal functionality. The re-examination of the relational model and the demand for spatial as well as temporal data types has driven the effort to create new types of databases. The capabilities of the spatial and temporal object database Tripod which is based on a spatio-temporal data type approach is the foundation for this study (Griffiths et al. 2001). A review of the moving-object model is made (Gueting et al. 2003) and its relation to the implemented Tripod data model is outlined, following the evolution on their common roots.PublishedNon Peer ReviewedGriffiths, T., Fernandes, A., Paton, N., Mason, K., Huang, B., Worboys, M. (2001) The Tripod Spatio-Historical Object Model, 20th International Conference on Conceptual Modelling (ER2001), Yokohama, Japan Gueting R. H., Boehlen M. H., Erwig M., Jensen C. S., Lorentzos N., Nardelli E., Schneider M., Viqueira J.R.R. (2003) Spatio-temporal Models: An Approach based on Data Types. Spatio-Temporal Databases – The Chorochronous Approach, T. Sellis et al. (Eds.): Spatio-temporal Databases, LNCS 2520, pp. 117-176, 200

    System simulation from operational data

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    A review of the evolution of spatio-temporal data types

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    Only the abstract and references were published in the proceedings. There is no full text.The motivation for this presentation is to show current approaches for modelling processes in time and space. Different approaches have taken place to extend existing RDBMS to spatio-temporal functionality. The re-examination of the relational model and the demand for spatial as well as temporal data types has driven the effort to create new types of databases. The capabilities of the spatial and temporal object database Tripod which is based on a spatio-temporal data type approach is the foundation for this study (Griffiths et al. 2001). A review of the moving-object model is made (Gueting et al. 2003) and its relation to the implemented Tripod data model is outlined, following the evolution on their common roots.PublishedNon Peer ReviewedGriffiths, T., Fernandes, A., Paton, N., Mason, K., Huang, B., Worboys, M. (2001) The Tripod Spatio-Historical Object Model, 20th International Conference on Conceptual Modelling (ER2001), Yokohama, Japan Gueting R. H., Boehlen M. H., Erwig M., Jensen C. S., Lorentzos N., Nardelli E., Schneider M., Viqueira J.R.R. (2003) Spatio-temporal Models: An Approach based on Data Types. Spatio-Temporal Databases – The Chorochronous Approach, T. Sellis et al. (Eds.): Spatio-temporal Databases, LNCS 2520, pp. 117-176, 200
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