527 research outputs found
The African-American Struggle for Equality: Two Divergent Approaches
This paper focuses on two leaders and how their divergent strategies for one goal led to them working together without actively coordinating their efforts. The research conducted in the paper is based primarily on the writings of Booker T. Washington and W. E. B. Du Bois. It examines their upbringing and their views on education, labor and voting rights
Carbonate-Clastic Synthems of the Middle Beekmantown Group in the Central and Southern Champlain Valley
Guidebook for field trips in Vermont: New England Intercollegiate Geological Conference, 79th annual meeting, October 16, 17 and 18, 1987: Trips C-4. Irregular pagination
Constructing Elliptic Curves over with Moderate Rank
We give several new constructions for moderate rank elliptic curves over
. In particular we construct infinitely many rational elliptic
surfaces (not in Weierstrass form) of rank 6 over using
polynomials of degree two in . While our method generates linearly
independent points, we are able to show the rank is exactly 6 \emph{without}
having to verify the points are independent. The method generalizes; however,
the higher rank surfaces are not rational, and we need to check that the
constructed points are linearly independent.Comment: 11 page
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Srs2 promotes synthesis-dependent strand annealing by disrupting DNA polymerase δ-extending D-loops.
Synthesis-dependent strand annealing (SDSA) is the preferred mode of homologous recombination in somatic cells leading to an obligatory non-crossover outcome, thus avoiding the potential for chromosomal rearrangements and loss of heterozygosity. Genetic analysis identified the Srs2 helicase as a prime candidate to promote SDSA. Here, we demonstrate that Srs2 disrupts D-loops in an ATP-dependent fashion and with a distinct polarity. Specifically, we partly reconstitute the SDSA pathway using Rad51, Rad54, RPA, RFC, DNA Polymerase δ with different forms of PCNA. Consistent with genetic data showing the requirement for SUMO and PCNA binding for the SDSA role of Srs2, Srs2 displays a slight but significant preference to disrupt extending D-loops over unextended D-loops when SUMOylated PCNA is present, compared to unmodified PCNA or monoubiquitinated PCNA. Our data establish a biochemical mechanism for the role of Srs2 in crossover suppression by promoting SDSA through disruption of extended D-loops
Valid and reliable assessment of wellness among adolescents: Do you know what you’re measuring?
Measuring wellness among adolescents is an emerging trend among professionals and researchers endeavouring to influence youth as they establish lifestyle patterns in this critical period of life. This discussion highlights instruments used to measure adolescents’ wellness, and considers the empirical data supporting the validity and reliability of those instruments. In summary, adolescents’ wellness is an important indicator of future health and lifestyle habits. There are a number of tools available to measure wellness, each with its own focus, depending on the definition or model from which it was developed. This might cause debate regarding the appropriateness of some instruments for evaluating wellness. The majority of wellness evaluation approaches used with adolescent populations have less than ideal validation. A ‘gold standard’ definition could lead to the standardisation of a theoretical model against which wellness instruments could be validated. The absence of peer-reviewed studies reporting psychometric testing for wellness evaluation instruments used with adolescents is of concern given their growing popularity and highlights a priority area for future research in this field
“Implementación de un sistema para control de posicionamiento angular de 1 eje en una estación fotovoltaica de 1 kw”
The purpose of this project is to implement a system to control the angular positioning of an axis, which will allow increasing the use of solar irradiance in a 1 kW photovoltaic station, due to the fact that currently the waste of solar energy captured by photovoltaic systems fixed is poor. In the first place, the research was carried out in bibliographic sources, where the solar inclination angles, types of tracking systems and range algorithms were studied.El propósito del presente proyecto es implementar un sistema para control de posicionamiento angular de un eje, el cual permitirá incrementar el aprovechamiento de la irradiancia solar en una estación fotovoltaica de 1 kW, debido a que actualmente el desaprovechamiento de la energía solar captada por sistemas fotovoltaicos fijos es deficiente. En primer lugar, se realizó la investigación en fuentes bibliográficas, donde se estudió los ángulos de inclinación solar, tipologías de sistemas de seguimiento y algoritmos de alcance
Spin-echo small-angle neutron scattering (SESANS) studies of diblock copolymer nanoparticles
Poly(glycerol monomethacrylate)–poly(benzyl methacrylate) (PGMA–PBzMA) diblock copolymer nanoparticles were synthesized via polymerization-induced self-assembly (PISA) using reversible addition–fragmentation chain-transfer (RAFT) aqueous emulsion polymerization in D2O. Such PISA syntheses produce sterically-stabilized nanoparticles in situ and can be performed at relatively high copolymer concentrations (up to 50 wt%). This PGMA–PBzMA formulation is known to form only spherical nanoparticles in water using aqueous emulsion polymerization (Macromolecules, 2014, 47, 5613–5623), which makes it an ideal model system for exploring new characterization methods. The polymer micelles were characterized using small-angle X-ray scattering (SAXS) and a recently developed form of neutron scattering, spin-echo small-angle neutron scattering (SESANS). As far as we are aware, this is the first report of a study of polymer micelles by SESANS, and the data agree well with reciprocal-space scattering. Using this technique enables characterization of the concentrated, as synthesized dispersions directly without dilution, and this will provide a method to study self-assembled polymer systems that have concentration dependent morphologies, while still maintaining the advantages of scattering techniques
Averting uncertainty: A practical guide to physical activity research in Australian schools
Preventative health has become central to contemporary health care, identifying youth physical activity as a key factor in determining health and functioning. Schools offer a unique research setting due to distinctive methodological circumstances. However, school-based researchers face several obstacles in their endeavour to complete successful research investigations; often confronted with complex research designs and methodological procedures that are not easily amenable to school contexts. The purpose of this paper is to provide a practical guide for teachers (both teacher educators and teaching practitioners) seeking to conduct physical activity-based research in Australian school settings, as well as discuss research practices. The research enabling process has been divided into six phases: preparation; design; outcome measures; procedures; participants; and feedback. Careful planning and consideration must be undertaken prior to the commencement of, and during the research process, due to the complex nature of school settings and research processes that exist in the Australian context
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