90 research outputs found
Humanizing Student–Teacher Relationships for Black Children: Implications for Teachers’ Social–Emotional Training
A growing number of scholars in the field of urban education compellingly demonstrate the myriad ways U.S. schooling for Black youth is dehumanizing. Social and emotional learning (SEL), particularly, transformative social emotional learning (TSEL) has come to the fore as a promising intervention to promote positive inclusive school cultures and relationships while recognizing and accounting for the realities of racial oppression. Here, we discuss teachers’ capacity to develop and negotiate student–teacher relationships that acknowledge and actively confront the dehumanization of Black youth in schools. We provide recommendations for teachers’ social emotional training that can effectively humanize learning environments for Black youth
Rotational master equation for cold laser-driven molecules
The equations of motion for the molecular rotation are derived for
vibrationally cold dimers that are polarized by off-resonant laser light. It is
shown that, by eliminating electronic and vibrational degrees of freedom, a
quantum master equation for the reduced rotational density operator can be
obtained. The coherent rotational dynamics is caused by stimulated Raman
transitions, whereas spontaneous Raman transitions lead to decoherence in the
motion of the quantized angular momentum. As an example the molecular dynamics
for the optical Kerr effect is chosen, revealing decoherence and heating of the
molecular rotation.Comment: 11 pages, 5 figures, to appear in Phys. Rev.
Hopf algebras and Markov chains: Two examples and a theory
The operation of squaring (coproduct followed by product) in a combinatorial
Hopf algebra is shown to induce a Markov chain in natural bases. Chains
constructed in this way include widely studied methods of card shuffling, a
natural "rock-breaking" process, and Markov chains on simplicial complexes.
Many of these chains can be explictly diagonalized using the primitive elements
of the algebra and the combinatorics of the free Lie algebra. For card
shuffling, this gives an explicit description of the eigenvectors. For
rock-breaking, an explicit description of the quasi-stationary distribution and
sharp rates to absorption follow.Comment: 51 pages, 17 figures. (Typographical errors corrected. Further fixes
will only appear on the version on Amy Pang's website, the arXiv version will
not be updated.
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The Physarum polycephalum Genome Reveals Extensive Use of Prokaryotic Two-Component and Metazoan-Type Tyrosine Kinase Signaling
Physarum polycephalum is a well-studied microbial eukaryote with unique experimental attributes relative to other experimental
model organisms. It has a sophisticated life cycle with several distinct stages including amoebal, flagellated, and plasmodial cells. It is
unusual in switching between open and closed mitosis according to specific life-cycle stages. Here we present the analysis of the
genome of this enigmatic and important model organism and compare it with closely related species. The genome is littered with
simple and complex repeats and the coding regions are frequently interrupted by introns with a mean size of 100 bases.
Complemented with extensive transcriptome data, we define approximately 31,000 gene loci, providing unexpected insights into
earlyeukaryoteevolution.Wedescribeextensiveuseofhistidinekinase-basedtwo-componentsystemsandtyrosinekinasesignaling,
the presence of bacterial and plant type photoreceptors (phytochromes, cryptochrome, and phototropin) and of plant-type pentatricopeptide
repeat proteins, as well as metabolic pathways, and a cell cycle control system typically found in more complex eukaryotes.
Our analysis characterizes P. polycephalum as a prototypical eukaryote with features attributed to the last common ancestor of
Amorphea, that is, the Amoebozoa and Opisthokonts. Specifically, the presence of tyrosine kinases inAcanthamoeba and Physarum
as representatives of two distantly related subdivisions ofAmoebozoa argues against the later emergence of tyrosine kinase signaling
in the opisthokont lineage and also against the acquisition by horizontal gene transfe
Spatializing the Ecological Leviathan: Territorial Strategies and the Production of Regional Natures
This paper explores a dual absence – the absence of the state within contemporary geographical analyses of nature; and the absence of nature within contemporary explorations of state power. We argue that the modern state continues to play a crucial role in framing social interactions with nature, while nature is still vital to states within their realization of different forms of material and ideological power. In order to reconnect analyses of the state and nature, this paper combines work on the production of nature and state strategy with Lefebvre’s recently translated writings on state space and territory. By focusing on the production of territory (or state space), we explore the interaction of the state and nature in the context of the political management of social and ecological space. We unravel the spatial entanglements of the state and nature through an analysis of the British state’s territorial strategies within the West Midlands region. By considering three key historical periods within the history of the West Mid-lands we reveal how the emergence of the regional space called the West Midlands is a product of the ongoing spatial dialectics of state and nature therein
Whole genome analysis of a schistosomiasis-transmitting freshwater snail
Biomphalaria snails are instrumental in transmission of the human blood fluke Schistosoma mansoni. With the World Health Organization's goal to eliminate schistosomiasis as a global health problem by 2025, there is now renewed emphasis on snail control. Here, we characterize the genome of Biomphalaria glabrata, a lophotrochozoan protostome, and provide timely and important information on snail biology. We describe aspects of phero-perception, stress responses, immune function and regulation of gene expression that support the persistence of B. glabrata in the field and may define this species as a suitable snail host for S. mansoni. We identify several potential targets for developing novel control measures aimed at reducing snail-mediated transmission of schistosomiasis
Global data on earthworm abundance, biomass, diversity and corresponding environmental properties
14 p.Earthworms are an important soil taxon as ecosystem engineers, providing a variety of crucial ecosystem functions and services. Little is known about their diversity and distribution at large spatial scales, despite the availability of considerable amounts of local-scale data. Earthworm diversity data, obtained from the primary literature or provided directly by authors, were collated with information on site locations, including coordinates, habitat cover, and soil properties. Datasets were required, at a minimum, to include abundance or biomass of earthworms at a site. Where possible, site-level species lists were included, as well as the abundance and biomass of individual species and ecological groups. This global dataset contains 10,840 sites, with 184 species, from 60 countries and all continents except Antarctica. The data were obtained from 182 published articles, published between 1973 and 2017, and 17 unpublished datasets. Amalgamating data into a single global database will assist researchers in investigating and answering a wide variety of pressing questions, for example, jointly assessing aboveground and belowground biodiversity distributions and drivers of biodiversity change
New insights into the genetic etiology of Alzheimer's disease and related dementias
Characterization of the genetic landscape of Alzheimer's disease (AD) and related dementias (ADD) provides a unique opportunity for a better understanding of the associated pathophysiological processes. We performed a two-stage genome-wide association study totaling 111,326 clinically diagnosed/'proxy' AD cases and 677,663 controls. We found 75 risk loci, of which 42 were new at the time of analysis. Pathway enrichment analyses confirmed the involvement of amyloid/tau pathways and highlighted microglia implication. Gene prioritization in the new loci identified 31 genes that were suggestive of new genetically associated processes, including the tumor necrosis factor alpha pathway through the linear ubiquitin chain assembly complex. We also built a new genetic risk score associated with the risk of future AD/dementia or progression from mild cognitive impairment to AD/dementia. The improvement in prediction led to a 1.6- to 1.9-fold increase in AD risk from the lowest to the highest decile, in addition to effects of age and the APOE ε4 allele
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