449 research outputs found
Ranking the efficiency of gas hydrate anti agglomerants through molecular dynamic simulations
- Author
- Publication venue
- 'American Chemical Society (ACS)'
- Publication date
- 01/01/2021
- Field of study
Using both computational and experimental methods, the capacity of four
different surfactant molecules to inhibit the agglomeration of sII hydrate
particles was assessed. The computational simulations were carried out using
both steered and non-steered Molecular Dynamics (MD), simulating the
coalescence process of a hydrate slab and a water droplet, both covered with
surfactant molecules. The experimental work was based on rocking cell
measurements, determining the minimum effective dose necessary to inhibit
agglomeration. Overall, good agreement was obtained between the performance
predicted by the simulations and the experimental measurements. Moreover, the
simulations allowed to gain additional insights that are not directly
accessible via experiments, such as an analysis of the mass density profiles,
the diffusion coefficients, or the orientations of the long tails
Recommended from our members
Contribution of H. pylori and Smoking Trends to US Incidence of Intestinal-Type Noncardia Gastric Adenocarcinoma: A Microsimulation Model
- Author
- Publication venue
- 'Public Library of Science (PLoS)'
- Publication date
- 21/05/2013
- Field of study
Background: Although gastric cancer has declined dramatically in the US, the disease remains the second leading cause of cancer mortality worldwide. A better understanding of reasons for the decline can provide important insights into effective preventive strategies. We sought to estimate the contribution of risk factor trends on past and future intestinal-type noncardia gastric adenocarcinoma (NCGA) incidence. Methods and Findings: We developed a population-based microsimulation model of intestinal-type NCGA and calibrated it to US epidemiologic data on precancerous lesions and cancer. The model explicitly incorporated the impact of Helicobacter pylori and smoking on disease natural history, for which birth cohort-specific trends were derived from the National Health and Nutrition Examination Survey (NHANES) and National Health Interview Survey (NHIS). Between 1978 and 2008, the model estimated that intestinal-type NCGA incidence declined 60% from 11.0 to 4.4 per 100,000 men, <3% discrepancy from national statistics. H. pylori and smoking trends combined accounted for 47% (range = 30%–58%) of the observed decline. With no tobacco control, incidence would have declined only 56%, suggesting that lower smoking initiation and higher cessation rates observed after the 1960s accelerated the relative decline in cancer incidence by 7% (range = 0%–21%). With continued risk factor trends, incidence is projected to decline an additional 47% between 2008 and 2040, the majority of which will be attributable to H. pylori and smoking (81%; range = 61%–100%). Limitations include assuming all other risk factors influenced gastric carcinogenesis as one factor and restricting the analysis to men. Conclusions: Trends in modifiable risk factors explain a significant proportion of the decline of intestinal-type NCGA incidence in the US, and are projected to continue. Although past tobacco control efforts have hastened the decline, full benefits will take decades to be realized, and further discouragement of smoking and reduction of H. pylori should be priorities for gastric cancer control efforts. Please see later in the article for the Editors' Summar
SoK: Contemporary Issues and Challenges to Enable Cyber Situational Awareness for Network Security
- Author
- Ahmed Abdulghani Ali
- Albanese Massimiliano
- Albanese Massimiliano
- Barford Paul
- Brynielsson Joel
- Collier Zachary A.
- Cooke Ian A.
- Dijcks Jean-Pierre
- Du Haitao
- Edward J.
- Endsley Mica R.
- Evesti Antti
- Ganesan Rajesh
- Holsopple Jared
- Jajodia Sushil
- Jajodia Sushil
- Jirsík Tomáš
- Jones Debra G.
- Kott Alexander
- Laštovička Martin
- Moskal Stephen
- Noel Steven
- Noel Steven
- Okutan Ahmet
- Skopik Florian
- Ward Jonathan Stuart
- Publication venue
- 'Association for Computing Machinery (ACM)'
- Publication date
- 01/01/2020
- Field of study
Cyber situational awareness is an essential part of cyber defense that allows the cybersecurity operators to cope with the complexity of today's networks and threat landscape. Perceiving and comprehending the situation allow the operator to project upcoming events and make strategic decisions. In this paper, we recapitulate the fundamentals of cyber situational awareness and highlight its unique characteristics in comparison to generic situational awareness known from other fields. Subsequently, we provide an overview of existing research and trends in publishing on the topic, introduce front research groups, and highlight the impact of cyber situational awareness research. Further, we propose an updated taxonomy and enumeration of the components used for achieving cyber situational awareness. The updated taxonomy conforms to the widely-accepted three-level definition of cyber situational awareness and newly includes the projection level. Finally, we identify and discuss contemporary research and operational challenges, such as the need to cope with rising volume, velocity, and variety of cybersecurity data and the need to provide cybersecurity operators with the right data at the right time and increase their value through visualization
2016 Research & Innovation Day Program
- Author
- Aguillon Natalia
- Alias Mary
- Bailey Kayla
- Baumann Julie
- Beardshaw Victoria
- Benbow Sarah
- Benbow Sarah
- Bennett John
- Berman Helene
- Bethune-Davies Pat
- Bilyea Ashley
- Bondy Meghan
- Bouchard Jessica
- Bourret-Gheysen Jesse
- Bowering Julia
- Broadfoot Sarah
- Cameron Jaimie
- Cechetto Kim
- Chin Ryan
- Churchill Alyssa
- Clendinning Kristen
- Cliffen Richard
- Co Kevin
- Cooper Karlie
- Cullen Maureen
- Currie Anthony
- Cutting Jessica
- Dave Paryank
- Desjardins Adam
- Docking Craig
- Donelle Lorie
- Donovan Kelly
- Drake Cole
- Dunn Brendan
- Dykstra Sarah
- Etmanskie Candice
- Farrell Matt
- Farrington Deion
- Ferreira Jonathan
- Figueiredo Ryan
- Fischer Kelsey
- Fisher Teresa
- Forchuk Cheryl
- Garzon Johanna
- Giffin Michelle
- Goosheh Seyed
- Gorlick Carolyne
- Graham Taylor
- Greenspan-Praktik Kevin
- Haaf Robert
- Hall Jodi
- Harrison Helen
- Hollinger Nick
- Humphrey Allan
- Ireland Nicholas
- Jenkins Karen
- Jenkins Karen
- Johns Bronwyn
- Johnston William
- Jones Billy
- Katsademas Karen
- Khadelwal Mona
- Klassen Zachary Alexander
- Kok Cameron
- Lam Caitlin
- Lambert Melissa
- Laverty Aisling
- Law Elliott
- Leclerc Nolan
- Loucks Megan
- Louwagie Jamie
- Macdonald Marissa
- Mallinger Catherine
- Maloney Kelly
- Marks Cassandra
- Martin Rick
- Mason Paige
- Mayr Marguerite
- McDonald Jordan
- McDonald Ken
- McLean Christian
- McMillan Amy
- Melon Cassandra
- Milley Jesse
- Muselmani Amal
- Myers Taylor
- Ngo Victoria
- O\u27Brien Karen
- Okonji Onyekachukwo
- Olakanye Feyisayo
- Pai Amol
- Painter Robin
- Parkhiya Jayeshbhai
- Patel Kajal
- Payne Jacqueline
- Pepe Kristina
- Pesant-Simpson Jessica
- Puppalwar Samiksha
- Ramji Asha
- Ranieri Lori
- Rawson Kaitlynn
- Relekar Pooja
- Rensby Jenny
- Richter Allyson
- Robins Chris
- Rodrigues Victoria
- Roodi Sam
- Ross Andrew
- Rudman Debbie
- Sadler Kate
- Sarkar Krittika
- Sherry Ashley
- Siddall Haylee
- Sloan Mike
- Smith Brad
- Smith Linnea
- Speck Allison
- Ste. Croix Dominique
- Stegmann Alex
- Sturm Peter
- Sudnicka Katie
- Taylor Megan
- Teng Serena
- Third Sheryl
- Thomas Candice
- Tulett Erin
- Usher Brittany
- Vadhvana Romik
- Valle Anthony
- Vandelaar Alana
- VanDenBrink Mike
- Vey Russell
- Vignault Carly
- Vijayakumar Vimoshana
- Walcher Matthew
- Waldie Phil
- Ward-Griffin Catherine
- Ware Alexander
- Weaver Holly
- Wilkins Jessica
- Woloszyn Annette
- Yassine Jessica
- Yip Chuck Anthony
- Young Todd
- Zareardalan Ronak
- Zeledon Joshua
- Publication venue
- FIRST: Fanshawe Innovation, Research, Scholarship, Teaching
- Publication date
- 01/01/2016
- Field of study
A one day showcase of applied research, social innovation, scholarship projects and activities.https://first.fanshawec.ca/cri_cripublications/1003/thumbnail.jp
Development of a Definition of Postacute Sequelae of SARS-CoV-2 Infection
- Author
- Alba George A
- Alicic Radica
- Altman Natasha
- Anglin Khamal
- Argueta Urania
- Ashktorab Hassan
- Atchley-Challenner Rachel
- Baslet Gaston
- Bassett Ingrid V
- Bateman Lucinda
- Bedi Brahmchetna
- Bhattacharyya Shamik
- Bind Marie-Abele
- Blomkalns Andra L
- Bonilla Hector
- Brim Hassan
- Bush Patricia A
- Castro Mario
- Chan James
- Charney Alexander W
- Chen Peter
- Chibnik Lori B
- Chu Helen Y
- Clifton Rebecca G
- Costantine Maged M
- Cribbs Sushma K
- Davila Nieves Sylvia I
- Deeks Steven G
- Duven Alexandria
- Emery Ivette F
- Erdmann Nathan
- Erlandson Kristine M
- Ernst Kacey C
- Farah-Abraham Rachael
- Farner Cheryl E
- Feuerriegel Elen M
- Fleurimont Judes
- Fonseca Vivian
- Foulkes Andrea S
- Franko Nicholas
- Gainer Vivian
- Gander Jennifer C
- Gardner Edward M
- Geng Linda N
- Gibson Kelly S
- Go Minjoung
- Goldman Jason D
- Grebe Halle
- Greenway Frank L
- Habli Mounira
- Hafner John
- Han Jenny E
- Hanson Keith A
- Heath James
- Hernandez Carla
- Hess Rachel
- Hodder Sally L
- Hoffman Matthew K
- Hoover Susan E
- Horwitz Leora I
- Huang Beatrice
- Hughes Brenna L
- Jagannathan Prasanna
- John Janice
- Jolley Sarah E
- Jordan Michael R
- Karlson Elizabeth W
- Katz Stuart D
- Kaufman Elizabeth S
- Kelly John D
- Kelly Sara W
- Kemp Megan M
- Kirwan John P
- Klein Jonathan D
- Knox Kenneth S
- Krishnan Jerry A
- Kumar Andre
- Laiyemo Adeyinka O
- Lambert Allison A
- Lanca Margaret
- Lee-Iannotti Joyce K
- Levitan Emily B
- Levy Bruce
- Logarbo Brian P
- Longo Michele T
- Luciano Carlos A
- Lutrick Karen
- Maley Jason H
- Mallett Gail
- Marathe Jai G
- Marconi Vincent
- Marshall Gailen D
- Martin Christopher F
- Matusov Yuri
- McComsey Grace A
- McCorkell Lisa
- Mehari Alem
- Mendez-Figueroa Hector
- Mermelstein Robin
- Metz Torri D
- Morse Richard
- Mosier Jarrod
- Mouchati Christian
- Mullington Janet
- Murphy Shawn N
- Nadkarni Girish N
- Neuman Robert B
- Nikolich Janko Z
- Ofotokun Ighovwerha
- Ojemakinde Elizabeth
- Palatnik Anna
- Palomares Kristy
- Parimon Tanyalak
- Parry Samuel
- Parthasarathy Sairam
- Patterson Jan E
- Patterson Thomas F
- Patzer Rachel E
- Peluso Michael J
- Pemu Priscilla
- Pettker Christian M
- Plunkett Beth A
- Pogreba-Brown Kristen
- Poppas Athena
- Quigley John G
- Reddy Uma
- Reece Rebecca
- Reeder Harrison
- Reeves W B
- Reiman Eric M
- Rischard Franz
- Rosand Jonathan
- Rouse Dwight J
- Ruff Adam
- Saade George
- Sandoval Grecio J
- Santana Jorge L
- Schlater Shannon M
- Schulte Carolin C M
- Sciurba Frank C
- Selvaggi Caitlin A
- Shepherd Fitzgerald
- Sherif Zaki A
- Shinnick Daniel J
- Simhan Hyagriv
- Singer Nora G
- Singh Upinder
- Skupski Daniel W
- Sowles Amber
- Sparks Jeffrey A
- Sukhera Fatima I
- Taylor Barbara S
- Teunis Larissa
- Thaweethai Tanayott
- Thomas Robert J
- Thorp John M
- Thuluvath Paul
- Ticotsky Amberly
- Tita Alan T
- Tuttle Katherine R
- Urdaneta Alfredo E
- Valdivieso Daisy
- VanWagoner Timothy M
- Vasey Andrew
- Verduzco-Gutierrez Monica
- Walker Tiffany A
- Wallace Zachary S
- Ward Honorine D
- Warren David E
- Weiner Steven J
- Welch Shelley
- Whiteheart Sidney W
- Wiley Zanthia
- Wisnivesky Juan P
- Yee Lynn M
- Zisis Sokratis
- Publication venue
- DigitalCommons@TMC
- Publication date
- 13/06/2023
- Field of study
IMPORTANCE: SARS-CoV-2 infection is associated with persistent, relapsing, or new symptoms or other health effects occurring after acute infection, termed postacute sequelae of SARS-CoV-2 infection (PASC), also known as long COVID. Characterizing PASC requires analysis of prospectively and uniformly collected data from diverse uninfected and infected individuals.
OBJECTIVE: To develop a definition of PASC using self-reported symptoms and describe PASC frequencies across cohorts, vaccination status, and number of infections.
DESIGN, SETTING, AND PARTICIPANTS: Prospective observational cohort study of adults with and without SARS-CoV-2 infection at 85 enrolling sites (hospitals, health centers, community organizations) located in 33 states plus Washington, DC, and Puerto Rico. Participants who were enrolled in the RECOVER adult cohort before April 10, 2023, completed a symptom survey 6 months or more after acute symptom onset or test date. Selection included population-based, volunteer, and convenience sampling.
EXPOSURE: SARS-CoV-2 infection.
MAIN OUTCOMES AND MEASURES: PASC and 44 participant-reported symptoms (with severity thresholds).
RESULTS: A total of 9764 participants (89% SARS-CoV-2 infected; 71% female; 16% Hispanic/Latino; 15% non-Hispanic Black; median age, 47 years [IQR, 35-60]) met selection criteria. Adjusted odds ratios were 1.5 or greater (infected vs uninfected participants) for 37 symptoms. Symptoms contributing to PASC score included postexertional malaise, fatigue, brain fog, dizziness, gastrointestinal symptoms, palpitations, changes in sexual desire or capacity, loss of or change in smell or taste, thirst, chronic cough, chest pain, and abnormal movements. Among 2231 participants first infected on or after December 1, 2021, and enrolled within 30 days of infection, 224 (10% [95% CI, 8.8%-11%]) were PASC positive at 6 months.
CONCLUSIONS AND RELEVANCE: A definition of PASC was developed based on symptoms in a prospective cohort study. As a first step to providing a framework for other investigations, iterative refinement that further incorporates other clinical features is needed to support actionable definitions of PASC
Optimasi Portofolio Resiko Menggunakan Model Markowitz MVO Dikaitkan dengan Keterbatasan Manusia dalam Memprediksi Masa Depan dalam Perspektif Al-Qur`an
- Author
- Aarrestad Thea Klaeboe
- Abbaneo Duccio
- Abbiendi Giovanni
- Abbrescia Marcello
- Abdullin Salavat
- Abdulsalam Abdulla
- Abercrombie Daniel
- Abu Zeid Shimaa
- Ackert Andrew
- Acosta Darin
- Acosta John Gabriel
- Adair Antony
- Adam Wolfgang
- Adams Jordon Rowe
- Adams Mark Raymond
- Adams Todd
- Adzic Petar
- Agapitos Antonis
- Aggleton Robin
- Agram Jean-Laurent
- Ahmad Ashfaq
- Ahmad Muhammad
- Ahmad Muhammad
- Ahmed Ijaz
- Ahuja Sudha
- Akchurin Nural
- Akgun Bora
- Al-bataineh Ayman
- Albergo Sebastiano
- Albert Andreas
- Albrow Michael
- Alcaraz Maestre Juan
- Aldaya Martin Maria
- Alderweireldt Sara
- Aldá Júnior Walter Luiz
- Aleksandrov Aleksandar
- Alexakhin Vadim
- Alexander James
- Alimena Juliette
- Allen Brandon
- Almond John
- Alunni Solestizi Luisa
- Alverson George
- Alves Fábio Lúcio
- Alves Gilvan
- Alyari Maral
- Amapane Nicola
- Amsler Claude
- Anagnostou Georgios
- Anderson Dustin
- Anderson Ian
- Andrea Jeremy
- Andreev Vladimir
- Andreev Yuri
- Andrews Michael Benjamin
- Androsov Konstantin
- Anelli Christopher
- Antonelli Louis
- Antropov Iurii
- Antunovic Zeljko
- Apanasevich Leonard
- Apollinari Giorgio
- Apresyan Artur
- Apyan Aram
- Arcaro Daniel
- Arcidiacono Roberta
- Arenton Michael Wayne
- Argiro Stefano
- Arneodo Michele
- Asavapibhop Burin
- Asawatangtrakuldee Chayanit
- Askew Andrew
- Attikis Alexandros
- Aubin Alexandre
- Auffray Etiennette
- Autermann Christian
- Auzinger Georg
- Avdeeva Ekaterina
- Avery Paul
- Avetisyan Aram
- Avila Carlos
- Azarkin Maksim
- Azhgirey Igor
- Aziz Tariq
- Azzi Patrizia
- Azzolini Virginia
- Azzurri Paolo
- Aşılar Ece
- Baarmand Marc M
- Baber Mark
- Bacchetta Nicola
- Bachmair Felix
- Bachtis Michail
- Baden Drew
- Baffioni Stephanie
- Bagliesi Giuseppe
- Bahinipati Seema
- Baillon Paul
- Bainbridge Robert
- Bakhshiansohi Hamed
- Ball Austin
- Ball Fionn
- Ban Yong
- Banerjee Sudeshna
- Banerjee Sunanda
- Bansal Sunil
- Barbagli Giuseppe
- Barberis Emanuela
- Barbieri Richard
- Bargassa Pedrame
- Baringer Philip
- Barker Anthony
- Barnes Virgil E
- Barney David
- Baron Owen
- Barone Luciano
- Barria Patrizia
- Barrio Luna Mar
- Bartek Rachel
- Barth Christian
- Bartosik Nazar
- Bartók Márton
- Baskakov Alexey
- Battilana Carlo
- Baty Austin
- Bauerdick Lothar AT
- Baumgartel Darin
- Baus Colin
- Bayshev Igor
- Bean Alice
- Beauceron Stephanie
- Beaudette Florian
- Beck Lana
- Beernaert Kelly
- Behera Prafulla Kumar
- Behnamian Hadi
- Behnke Olaf
- Behrens Ulf
- Bein Samuel
- Beirão Da Cruz E Silva Cristóvão
- Belchior Batista Das Chagas Ewerton
- Belforte Stefano
- Beliy Nikita
- Belknap Donald
- Bell Ken W
- Bellan Riccardo
- Belloni Alberto
- Beluffi Camille
- Belyaev Alexander
- Belyaev Andrey
- Benato Lisa
- Bencze Gyorgy
- Bendavid Joshua
- Benelli Gabriele
- Beni Noemi
- Benussi Luigi
- Benvenuti Alberto
- Beranek Sarah
- Beretvas Andrew
- Bergauer Thomas
- Berger Joram
- Beri Suman Bala
- Bernardes Cesar Augusto
- Bernardini Jacopo
- Bernet Colin
- Berry Douglas
- Berry Edmund
- Berryhill Jeffrey
- Bertl Willi
- Besancon Marc
- Betchart Burton
- Betts Russell Richard
- Bhandari Rohan
- Bhardwaj Ashutosh
- Bhat Pushpalatha C
- Bhatnagar Vipin
- Bhattacharya Rajarshi
- Bhattacharya Saptaparna
- Bhattacharya Satyaki
- Bhawandeep Bhawandeep
- Bhopatkar Vallary
- Bhowmik Sandeep
- Bi Ran
- Bialkowska Helena
- Bian Jian-Guo
- Bianchini Lorenzo
- Bianco Stefano
- Bierwagen Katharina
- Biino Cristina
- Bilei Gian Mario
- Bilin Bugra
- Bilki Burak
- Bilmis Selcuk
- Bin Anuar Afiq Aizuddin
- Bisello Dario
- Bitioukov Sergei
- Blekman Freya
- Blinov Vladimir
- Blobel Volker
- Bloch Daniel
- Bloch Philippe
- Bloom Kenneth
- Bluj Michal
- Blumenfeld Barry
- Boccali Tommaso
- Bocci Andrea
- Bodek Arie
- Boimska Bożena
- Boletti Alessio
- Bolla Gino
- Bonacorsi Daniele
- Bonato Alessio
- Bondu Olivier
- Boos Edouard
- Boren Samuel
- Bornheim Adolf
- Borras Kerstin
- Bortignon Pierluigi
- Borzou Ahmad
- Bose Tulika
- Botta Cristina
- Boudoul Gaelle
- Bouhali Othmane
- Bourilkov Dimitri
- Bouvier Elvire
- Bowen James
- Bradmiller-Feld John
- Braghieri Alessandro
- Braibant-Giacomelli Sylvie
- Brandstetter Johannes
- Brandt Stephanie
- Branson James G
- Breedon Richard
- Breto Guillermo
- Brew Christopher
- Brianza Luca
- Brigliadori Luca
- Brigljevic Vuko
- Brinkerhoff Andrew
- Brinson Jessica
- Brito Lucas
- Brochero Cifuentes Javier Andres
- Brochet Sébastien
- Brodski Michael
- Brom Jean-Marie
- Brondolin Erica
- Brooke James John
- Brown Robert M
- Brun Hugues
- Bruner Christopher
- Bruno Giacomo
- Buchmuller Oliver
- Bucinskaite Inga
- Bundock Aaron
- Bunkowski Karol
- Bunn Julian
- Buontempo Salvatore
- Burkett Kevin
- Burns Douglas
- Burns Dustin
- Burt Kira
- Burton Darren
- Busson Philippe
- Busza Wit
- Butler Joel Nathan
- Butler Philip H
- Buttignol Michael
- Butz Erik
- Bylinkin Alexander
- Bylsma Ben
- Byszuk Adrian
- Bäni Lukas
- Cabrera Andrés
- Cabrillo Iban Jose
- Cadamuro Luca
- Caillol Cécile
- Cakir Altan
- Calabria Cesare
- Calderon De La Barca Sanchez Manuel
- Calderon Alicia
- Cali Ivan Amos
- Call Kenneth
- Calligaris Luigi
- Calpas Betty
- Calvelli Valerio
- Calvert Brian
- Calvo Enrique
- Caminada Lea
- Campagnari Claudio
- Campanini Renato
- Campbell Alan
- Camporesi Tiziano
- Candelise Vieri
- Canelli Maria Florencia
- Cankocak Kerem
- Capiluppi Paolo
- Caputo Claudio
- Carlin Roberto
- Carnes Andrew
- Carpinteyro Severiano
- Carrera Jarrin Edgar
- Carrillo Montoya Camilo Andres
- Carrillo Moreno Salvador
- Cartiglia Nicolo
- Carvalho Antunes De Oliveira Alexandra
- Carvalho Wagner
- Carver Matthew
- Casal Bruno
- Casarsa Massimo
- Casasso Stefano
- Castaldi Rino
- Castello Roberto
- Castilla-Valdez Heriberto
- Castiñeiras De Saa Juan Ramon
- Castle James
- Castro Andrea
- Caudron Adrien
- Cavallari Francesca
- Cavallo Francesca Romana
- Cavallo Nicola
- Cavanaugh Richard
- Celik Ali
- Centis Vignali Matteo
- Cepeda Maria
- Cerati Giuseppe Benedetto
- Cerci Salim
- Cerminara Gianluca
- Cerrada Marcos
- Chabert Eric Christian
- Chadeeva Marina
- Chamizo Llatas Maria
- Chang Paoti
- Chang You-Hao
- Chang Yu-Wei
- Chanon Nicolas
- Chao Yuan
- Chaparro Sierra Luisa Fernanda
- Chapon Emilien
- Charaf Otman
- Charlot Claude
- Chatterjee Kalyanmoy
- Chatterjee Rajdeep Mohan
- Chauhan Shubhanshu
- Chauhan Sushil
- Chaves Jorge
- Chawla Ridhi
- Chen Geng
- Chen Guo-Ming
- Chen He-Sheng
- Chen Kai-Feng
- Chen Mingshui
- Chen Po-Hsun
- Chen Ye
- Chen Yi
- Chen Zhenyu
- Chenarani Shirin
- Cheng Tongguang
- Cherepanov Vladimir
- Chertok Maxwell
- Cheung Harry
- Chhibra Simranjit Singh
- Chierici Roberto
- Chinellato Jose
- Chiorboli Massimiliano
- Chistov Ruslan
- Chlebana Frank
- Cho Sungwoong
- Choi Minkyoo
- Choi Suyong
- Choi Young-Il
- Chou John Paul
- Choudhary Brajesh C
- Choudhury Somnath
- Chtchipounov Leonid
- Chu Jennifer
- Chudasama Ruchi
- Chwalek Thorsten
- Ciangottini Diego
- Cieri Davide
- Cihangir Selcuk
- Cimmino Anna
- Ciocci Maria Agnese
- Cipriani Marco
- Cirkovic Predrag
- Citron Matthew
- Cittolin Sergio
- Ciulli Vitaliano
- Civinini Carlo
- Claes Daniel R
- Clare Robert
- Clarida Warren
- Clarke Christopher
- Clement Emyr
- Clerbaux Barbara
- Cockerill David JA
- Cocoros Alice
- Codispoti Giuseppe
- Colafranceschi Stefano
- Colaleo Anna
- Cole Joanne
- Colino Nicanor
- Collard Caroline
- Colling David
- Colombo Fabio
- Connor Patrick
- Contardo Didier
- Conte Eric
- Contreras-Campana Christian
- Contreras-Campana Emmanuel
- Conway John
- Conway Rylan
- Cooper Seth
- Cooperstein Stephane
- Cornelis Tom
- Corpe Louie
- Cossutti Fabio
- Costa Marco
- Costa Salvatore
- Costanza Francesco
- Coubez Xavier
- Couderc Fabrice
- Coughlan John A
- Courbon Benoit
- Cousins Robert
- Covarelli Roberto
- Cowden Christopher
- Cox Bradley
- Cox Peter Timothy
- Creanza Donato
- Cremonesi Matteo
- Cristella Leonardo
- Cuevas Javier
- Cuffiani Marco
- Cumalat John Perry
- Curras Esteban
- Curry David
- Cussans David
- Custódio Analu
- Cutts David
- Czellar Sandor
- D'Alessandro Raffaello
- D'Alfonso Mariarosaria
- D'Enterria David
- D'Hondt Jorgen
- D'imperio Giulia
- Da Silveira Gustavo Gil
- Dabrowski Anne
- Daci Nadir
- Dalchenko Mykhailo
- Dall'Osso Martino
- Dallavalle Gaetano-Marco
- Damarseckin Serdal
- Damgov Jordan
- Danilov Mikhail
- Daponte Vincenzo
- Das Souvik
- Daskalakis Georgios
- Dasu Sridhara
- Dauncey Paul
- David Tinoco Mendes Andre
- Davies Gavin
- Davignon Olivier
- de Barbaro Pawel
- De Boer Wim
- De Bruyn Isabelle
- De Castro Manzano Pablo
- De Cosa Annapaola
- De Filippis Nicola
- De Gruttola Michele
- De Guio Federico
- De Jesus Damiao Dilson
- De La Cruz Begona
- De La Cruz-Burelo Eduard
- De Lentdecker Gilles
- De Mattia Marco
- De Moraes Gregores Eduardo
- De Nardo Guglielmo
- De Oliveira Martins Carley
- De Palma Mauro
- De Remigis Paolo
- De Roeck Albert
- de Trocóniz Jorge F
- De Visscher Simon
- De Wit Adinda
- De Wolf Eddi A
- Degano Alessandro
- Deiters Konrad
- Dejardin Marc
- Del Re Daniele
- Delaere Christophe
- Delannoy Andrés G
- Delannoy Hugo
- Delcourt Martin
- Delgado Peris Antonio
- Delgado Andrea
- Dell'Orso Roberto
- Della Negra Michel
- Della Ricca Giuseppe
- Demaria Natale
- Demina Regina
- Demiragli Zeynep
- Demiroglu Zuhal Seyma
- Denegri Daniel
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- Northup Michael
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- Yazgan Efe
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- Yetkin Elif Asli
- Yetkin Taylan
- Yi Kai
- Yilmaz Yetkin
- Yohay Rachel
- Yonamine Ryo
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- Yoo Jaehyeok
- You Can
- Yu Geum Bong
- Yu Intae
- Yu Shin-Shan
- Yumiceva Francisco
- Yusli Mohd Nizam
- Zabel James
- Zabi Alexandre
- Zaganidis Nicolas
- Zagoździńska Agnieszka
- Zakaria Mohammed
- Zalewski Piotr
- Zanetti Anna
- Zanetti Marco
- Zarubin Anatoli
- Zeinali Maryam
- Zenoni Florian
- Zenz Seth Conrad
- Zeuner Wolfram Dietrich
- Zevi Della Porta Giovanni
- Zeyrek Mehmet
- Zghiche Amina
- Zhang Fengwangdong
- Zhang Huaqiao
- Zhang Jingyu
- Zhao Jingzhou
- Zhokin Alexander
- Zhu Ren-Yuan
- Zhukov Valery
- Zhukova Victoria
- Zientek Margaret
- Zolkapli Zukhaimira
- Zorbakir Ibrahim Soner
- Zorbilmez Caglar
- Zotto Pierluigi
- Zou David
- Zsigmond Anna Julia
- Zucchetta Alberto
- Zumerle Gianni
- Zuranski Andrzej
- Publication venue
- Sunan Kalijaga State Islamic University
- Publication date
- 01/01/2012
- Field of study
Risk portfolio on modern finance has become increasingly technical, requiring the use of sophisticated mathematical tools in both research and practice. Since companies cannot insure themselves completely against risk, as human incompetence in predicting the future precisely that written in Al-Quran surah Luqman verse 34, they have to manage it to yield an optimal portfolio. The objective here is to minimize the variance among all portfolios, or alternatively, to maximize expected return among all portfolios that has at least a certain expected return. Furthermore, this study focuses on optimizing risk portfolio so called Markowitz MVO (Mean-Variance Optimization). Some theoretical frameworks for analysis are arithmetic mean, geometric mean, variance, covariance, linear programming, and quadratic programming. Moreover, finding a minimum variance portfolio produces a convex quadratic programming, that is minimizing the objective function ðð¥with constraintsð ð 𥠥 ðandð´ð¥ = ð. The outcome of this research is the solution of optimal risk portofolio in some investments that could be finished smoothly using MATLAB R2007b software together with its graphic analysis
Impact of opioid-free analgesia on pain severity and patient satisfaction after discharge from surgery: multispecialty, prospective cohort study in 25 countries
- Author
- Aamir Faiqa Binte
- Aamir Syed Roohan
- Ababneh Adnan
- Abbal Muhammad Anas
- Abbas Ahmed M
- Abbas Mostafa
- Abd-Albain Montasir A
- Abdalei Abdulwahab
- Abdalla Ahmed
- Abdalla Ahmed Yassir
- Abdalla Mohamed Galal Ali
- Abdalla Zainab
- Abdallah Mohamed M
- Abdalmahmoud Noon Ezzeldien
- Abdalsadeg Rowa
- Abdelaal Ahmed M
- Abdelbagi Alnazeer Y
- Abdelbaky Mostafa
- Abdelbaset Doaa
- AbdElbaset Esraa
- Abdelbast Menhag
- Abdelfatah Mohammed Abdelnasser
- Abdelgawad Samia
- Abdelhamid Mohamed M
- Abdeljaber Mahmoud
- Abdelkhalig Mubarak
- Abdelmaksoud Mohamed
- Abdelmeguid Rana
- Abdelmelek Dhia Errahmane
- Abdelnaeam Samah
- Abdelnasser Mohammad K
- Abdelrahim Najwa
- Abdelrahman Amira
- Abdelrahman Ayman
- Abdelsalam Hebatalla
- Abdelsamed Enas Abdelbaset
- Abdelwahab Khaled
- Abdoun Meriem
- Abdulali Fatima
- Abdulaziz Mohamed
- Abdulla Dheba Almukhtar
- Abdullah Bahiyah
- Abdullah Bahiyah
- Abdullah Walaa
- Abdullahi Habiba Ibrahim
- Abdulrahman Ahmed
- Abdulrasheed Lubabatu
- Abdulwahed Eman
- Abdulwahed Eman
- Abeysirigunawardana Dewmi
- Abidin Muhammad Fihmi Zainal
- Abiola Olukayode
- Abiyere Henry
- Abodina Ahmed Mohammed
- Aboelela Reham
- AboElfarh Hadeer Elsaeed
- Aboudlal Husein
- AbouHiekal Osama
- Aboulfotouh Ahmed
- Abozid Anwaar
- Abubaker Noora
- Abubaker Noora
- Abufanas Asma
- Abughanima Mahmoud
- Abuhashem Shehab
- Abulafia Daniel
- Abushaala Fatima
- Abushanab Khaled
- AbuShawareb Issa
- Abuuqteish Hamza
- Abuzaho Amany
- Achem Arome
- Adam Eithar
- Adam Mohammed
- Adam Mohammed A
- Addalla Mohamed
- Addley Jordan
- Adeleye Gbadebo
- Adeniyi Adebayo
- Adewole Nathaniel
- Adeyemo Olabisi
- Adeyeye Ademola
- Adeyeye Ademola
- Adly Michael
- Adnan Siti Nasyirah Nisya
- Ads Adel Mohamed
- Ads Alaa Mohamed
- Adze Joel Amwe
- Afeikhena Ehis
- Agida Teddy
- Agilla Hamza
- Agnew Emilie
- Agu Joy Onyekachi
- Ahmad Zatul Akmar
- Ahmed Abdalla
- Ahmed Ahmed
- Ahmed Ahmed
- Ahmed Alaaaldeen
- Ahmed Entisar
- Ahmed Habeeba
- Ahmed Hatem
- Ahmed Reem
- Ahmed Rehab
- Ahmed Rihab
- Ahmed Rogia Ahmed Abdalla
- Ahmed Ruaa
- Ahmed Sharwany
- Ahmed Uzair
- Ahmed Wahiba
- Ahmeed Sultan
- Airede Lydia Regina
- Aitchison Lori
- Ajredini Mirac
- Ajulo Adeshina A
- Akaba Godwin
- Akasha Mazin
- Akbar Maha Ghulam
- Akbuz Seyma Orcan
- Akdere Hakan
- Akın Bilge
- Akkaya Ege Nur
- Akpamgbo Chukwunonso Nnamdi
- Akwaisah Ayoub
- Al Hammoud Amr
- Al Rawashdeh Toka
- Al-Baw Mahmoud
- Al-Dahdouh Mosheer
- Al-Haek Safa’
- Al-Hazaimeh Mo'ath
- Al-issawi Dima
- Al-Issawi Subhi
- Al-jammal Maryam
- Al-Juaifari Maytham A
- Al-Mwajeh Tesneem
- Al-Omary Sohaib
- Al-Quossi Mohammed
- Al-Shambaty Yasir Babkir Ali
- Al-Shami Qotadah
- Al-Smirat Heba
- Al-Tahayneh Sief-Addeen
- Al-Touny Aiman
- Al-Touny Shimaa
- Al-zawaydeh Alia
- Alaa Ali
- Alabed Ebtihal
- Alagelli Fatma
- Alagoz Ahmet Can
- Alameen Hind
- Alameen Maram
- Alamlih Laith
- Alaqoubi Retaj
- Alarabi Rehab
- Alariby Fatima
- Alatefi Dawood
- Alathameen Nassar
- Albakosh Bashir Abobaker
- Albanopoulos Konstantinos
- Albarhomy Osama
- Albarki Aisha
- Albashaireh Alaa
- Albatni Safa Sasi
- Albayadi Eslam
- Alboon Mosab
- Alboridy Muneera
- Alboueishi Asraa Ali
- Aldeges Marwan
- Aldreawi Mohammed
- Alflite Asil Omar Saleh
- Alfrijat Tamam
- Alfrjani Tariq
- Algabbasi Salima
- Algatanesh Nassib
- Alhadad Qamrah
- Alhaddad Hoda Salem
- Alhaleem Ayah
- Alhaleeq Saif
- Alharam Abtisam
- Alhashimi Abdulhadi Mohammed Alhadi
- Alhassan Monzer
- Alhudhairy Sara
- Ali Ahmed
- Ali Aml
- Ali Doua
- Ali Eithar M
- Ali Iqra Fatima Munawar
- Ali Maab
- Ali Manal
- Ali Muhammad
- Ali Radwa
- Ali Rawan Alsheikh
- Ali Rzan Ali Hamedelneel
- Ali Shehroz
- Aliosin Oleg
- Aljamal Mohammad
- Aljamal Sarah
- Alkaraja Layth
- Alkaseek Akram
- Alkazali Mustafa
- Alkchr Hayat Ben Hasan Mohamed A A
- Alkhatib Abed Alazeez
- Allam Shereen
- Almahroush Marin
- Almakki Doha Mohammed Ahmed
- Alnajjar Lara
- Alnajjar Majjd
- Alnatsheh Wesam
- Alnour Ammar
- Alomar Rabiaa
- Alomari Yazan
- Alqaarh Aya
- Alragig Zahra
- Alrifae Ghaliya Mohamed H
- Alrosan Risan
- Alsagoff Sharifah Nor Amirah Syed Abdul Latiff
- Alsaid Hamza
- Alsaify Esmat
- Alsaih Sawsan
- Alsari Najah
- Alshareea Entisar
- Alshawadfy Abdelrhman
- Alshawesh Aisha
- Alsheik Ahmad
- Alsori Mohamed
- Alsoudani Ali
- Altabbaa Hashem
- Altahir Mohamed
- Altair Mawadda
- Altaweel Ahmad
- Altughar Bushra
- Alvarez Matias
- Alvarez-Lozada Luis Adrian
- Alvarez-Lozada Luis Adrian
- Alwahaib Anas
- Alwash Mohammed
- Alzarga Ali
- Alzarouq Ebtisam
- Alzarroug Amal
- Alzghoul Bader
- Alzyoud Osama
- Amarasekara Mishka
- Amary Marwa
- Ametov Amet
- Amin Mostafa K
- Aminu Bashiru
- Aminu Muhammad Baffah
- Ammar Ahmed Siddique
- Amro Dana
- Ananthapadmanabhan Shravankrishna
- Anderson Paul
- Andrew Paul Chimezie
- Andriani Adelaide
- Anestiadou Elissavet
- Angelis Fragkiskos
- Angeslis Fragkiskos
- Aqeel Syed Talha Bin
- Aral Canan
- Arebi Jaber
- Arnaoutoglou Eleni
- Arslangilay Mert
- Arvanitaki Alexandra
- Asadyari-Lupo Shadie
- Ashar Nur Ayuni Khirul
- Ashour Amira
- Ashraf Hamza
- Ashur Abir Ben
- Asjad Imran
- Askar Aamal
- Askin Abdullah Emre
- Aslam Muhammad Nadeem
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- Zakaria Mohd Zaim
- Zalloum Jihad
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- Zambon Mattia
- Zapsalis Konstantinos
- Zargar Kamran
- Zarzour Mohamed A
- Zeng Raymond
- Zeng Raymond
- Zengin Kagan
- Zertuche Juventino Tadeo Guerrero
- Zhang Caitlin
- Zhang Edward
- Zhang Shane
- Zhang Yichi
- Zhao Hailin
- Zheng Helen
- Zhou Karen
- Zhou Yida
- Ziergiebel Felix
- Zou Peishan
- Zuylekom Kate Van
- Zuylekom Katie Van
- Zwain Yasir Adnan
- Zyul'korneeva Sof'ya
- Aladna Abdallah
- Aljoumaa Abdullah
- Nawfal Hamdi
- Niazi Ammar
- Publication venue
- Publication date
- 01/01/2024
- Field of study
Background: Balancing opioid stewardship and the need for adequate analgesia following discharge after surgery is challenging. This study aimed to compare the outcomes for patients discharged with opioid versus opioid-free analgesia after common surgical procedures.Methods: This international, multicentre, prospective cohort study collected data from patients undergoing common acute and elective general surgical, urological, gynaecological, and orthopaedic procedures. The primary outcomes were patient-reported time in severe pain measured on a numerical analogue scale from 0 to 100% and patient-reported satisfaction with pain relief during the first week following discharge. Data were collected by in-hospital chart review and patient telephone interview 1 week after discharge.Results: The study recruited 4273 patients from 144 centres in 25 countries; 1311 patients (30.7%) were prescribed opioid analgesia at discharge. Patients reported being in severe pain for 10 (i.q.r. 1-30)% of the first week after discharge and rated satisfaction with analgesia as 90 (i.q.r. 80-100) of 100. After adjustment for confounders, opioid analgesia on discharge was independently associated with increased pain severity (risk ratio 1.52, 95% c.i. 1.31 to 1.76; P < 0.001) and re-presentation to healthcare providers owing to side-effects of medication (OR 2.38, 95% c.i. 1.36 to 4.17; P = 0.004), but not with satisfaction with analgesia (beta coefficient 0.92, 95% c.i. -1.52 to 3.36; P = 0.468) compared with opioid-free analgesia. Although opioid prescribing varied greatly between high-income and low- and middle-income countries, patient-reported outcomes did not.Conclusion: Opioid analgesia prescription on surgical discharge is associated with a higher risk of re-presentation owing to side-effects of medication and increased patient-reported pain, but not with changes in patient-reported satisfaction. Opioid-free discharge analgesia should be adopted routinely
Finishing the euchromatic sequence of the human genome
- Author
- . Haifeng
- . Magner
- . Yin
- Abbott Scott
- Abbott-Ozersky Amanda
- Abdellah Zahra
- Abouelleil Amr
- Abrajano Anne
- Adachi Tamami
- Adam Catherine
- Adams Charles Q.
- Adamson Aaron
- Adekoya Emmanuel
- Adio-Oduola Babajide
- Aerts Andrea
- Aggarwal Arun
- Ahmadi Alireza
- Ahmed Shahana
- Aimable Matthew
- Ainscough Rachael
- Ait-Zahra Mostafa
- Aizu Tomoyuki
- Alcivare Dana
- Alegria Michelle
- Ali Alla
- Ali Johar
- Allegria-hartmann Michelle
- Alleman Jennifer
- Allen Carlana C.
- Allen Heather
- Allen Nicole R.
- Allen Susan
- Allen Thaddeus
- Almeida Jeff
- Almond Claire
- Alsbrooks Stephen L.
- Altherr Michael R.
- Amaratunge Harshinie C.
- Ambler Andrew
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- Amemiya Chris
- Amico-Keller Gina
- Amin Amita G.
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- Anderson Scott
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- Anthouard Véronique
- Antonarakis Stylianos E.
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- Dimitrijevic-Bussod Mira
- Ding Hao
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- Ding Li
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- Dinh Huyen H.
- Dixon Kami
- Do Long
- Dobbs Ruth
- Dobson Richard
- Dockree Catherine
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- Dodsworth Steven
- Doggett Norman
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- Dong Hui
- Dong Kimberly
- Dong Wei
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- Dong Xiaojia
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- Dorje Passang
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- Doucette-Stamm Lynn
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- Du Feiyu
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- Dubchak Inna
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- Dutta Ireena
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- Eckenberg Ralph
- Edgar Darren
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- Edwards Karen
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- Elkin Chris
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- Erler Anne Marie
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- Evans Gareth
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- Eveleth Gerald
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- Footman Simon
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- Fuller Liam
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- Garcia-Martinez Antonio
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- Gardner Alison
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- Han Guiqing
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- Hancock Julie
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- Hitchens Matthew Edward
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- Krawczyk Marie-Claude
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- Kube Michael
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- Pahlavan Shane
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- Tian Chaoguang
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- Togashi Naoko
- Tomizawa Iori
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- Wangdi Tsering
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- Wickremasinghe Manosha I.
- Widaa Sara
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- Wilkinson Jane
- Wilkinson Jane
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- Williams Andy
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- Williamson Helen
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- Wilson Steve
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- Wohldmann Patty
- Wollard Jessica
- Womack Andrew W.
- Wong Benjamin
- Wong Gane K-S
- Wood Diane
- Wood Emma
- Wood Joe
- Wooden Hailey S.
- Wooden Steven H.
- Woodeson Sharon
- Woodfine Kathryn
- Woodmansey Rebecca
- Woods Eric
- Woodwark Cara
- Wooster Richard
- Worley Kim Carlyle
- Woyke Tanja
- Wray Matthew
- Wray Paul
- Wright Charmain
- Wright Debbie
- Wright Kathrine
- Wright Kristin
- Wright Rita A.
- Wu Chungen
- Wu Dongying
- Wu Jiaqian
- Wu Jung-Rung
- Wu Kevin
- Wu Qingfa
- Wu Qingfa
- Wu Ruiming
- Wu Xiao
- Wu Xiaojing
- Wu Zaining
- Wyatt Julia
- Wycoff-Montenegro Melissa
- Wylie Kris
- Wyman Dudley
- Wyman Stacia
- Xi Yan
- Xi Yingying
- Xie Fei
- Xie Gary
- Xie Jane
- Xiong Hui
- Xiong Yuqing
- Xu Alex
- Xu Jing
- Xu Jing
- Xu Ruqin
- Xu Shuhua
- Xu Wei
- Xu Xinlai
- Xu Yan
- Xu Yuning
- Xu Zhihong
- Xu Zuyuan
- Xuan Yali
- Xuan Zhenyu
- Xue Rui
- Yada Tetsushi
- Yadav Shailendra
- Yakub Syed
- Yamamoto Lynn
- Yamamoto Noriko
- Yamamoto Yuko
- Yamashita Yasue
- Yamazaki Satoru
- Yang Hao
- Yang Huanming
- Yang Huanming
- Yang Joan
- Yang Shiaw-Pyng
- Yang Shudong
- Yang Xiaonan
- Yang Xiaonan
- Yang Xiaoping
- Yang Yongkui
- Yano Candance
- Yao Zhijian
- Yao Zhijian
- Yaspo Marie-Laure
- Ye Chen
- Yeager Shane
- Yeh Mimi
- Yen Jennifer
- Yeshitela Rahel Retta
- Yoakum Martin
- Yokobata Kathy
- Yokoyama Jennifer
- Yonezawa Miho
- Yoon Lillienne
- Yoon Vivienne
- Yoshida Satoru
- You Bo
- Young Geneva
- Young Louise
- Young Shelia
- Younger Ruth
- Yu Bing
- Yu Charles
- Yu Fuli
- Yu Jun
- Yu Jun
- Yu Jun
- Yuan Kaiwen
- Yuan Ye
- Yuan Yida
- Yue Shujie
- Yumae Brian
- Yun Rui
- Zainoun Joanne
- Zembeck Lisa
- Zeng Yixin
- Zhai Dong
- Zhan Guoping
- Zhang Bo
- Zhang Caimin
- Zhang Fengmei
- Zhang Guangyu
- Zhang Guohua
- Zhang Guohua
- Zhang Haiqing
- Zhang Haiqing
- Zhang Haiqing
- Zhang Hongbo
- Zhang Hongbo
- Zhang Jingjing
- Zhang Jingjing
- Zhang Jingkun
- Zhang Jiuchun
- Zhang Jiuchun
- Zhang Lanzhi
- Zhang Li
- Zhang Li
- Zhang Meihua
- Zhang Meng
- Zhang Ming
- Zhang Qing
- Zhang Ruhua
- Zhang Shaojie
- Zhang Tiezhen
- Zhang Wei
- Zhang Wei
- Zhang Xianglin
- Zhang Xianglin
- Zhang Xiaoliang
- Zhang Xiuqing
- Zhang Yan
- Zhang Yi
- Zhang Yilin
- Zhang Yilin
- Zhang Ying
- Zhang Yuansen
- Zhang Yuzhi
- Zhang Zhengdong
- Zhao Hongmei
- Zhao Lijian
- Zhao Shenru
- Zhao Zhijing
- Zhen Zhicheng
- Zheng Haibo
- Zhong Ming
- Zhou Carol
- Zhou Haixia
- Zhou Jianling
- Zhou Nannan
- Zhou Xinfeng
- Zhou Yan
- Zhou Yang
- Zhou Yi
- Zhu Bingying
- Zhu Bofeng
- Zhu Fenghua
- Zhu Genfeng
- Zhu Genfeng
- Zhu Miao
- Zhu Ning
- Zhu Yongge
- Zhu Zhen
- Zhuang Shitao
- Zierten Deborah
- Zimmer Andrew
- Zody Michael C.
- Zollo Massimo
- Zorrilla Sara E.
- Zuo Lin
- Publication venue
- LSU Digital Commons
- Publication date
- 21/10/2004
- Field of study
The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead
Physics case for an LHCb Upgrade II - Opportunities in flavour physics, and beyond, in the HL-LHC era
- Author
- Aaij Roel
- Adeva Bernardo
- Adinolfi Marco
- Aidala Christine Angela
- Ajaltouni Ziad
- Akar Simon
- Albicocco Pietro
- Albrecht Johannes
- Alessio Federico
- Alexander Michael
- Alfonso Albero Alejandro
- Ali Suvayu
- Alkhazov Georgy
- Alvarez Cartelle Paula
- Alves Jr Antonio Augusto
- Amato Sandra
- Amerio Silvia
- Amhis Yasmine
- An Liupan
- Anderlini Lucio
- Andreassi Guido
- Andreotti Mirco
- Andrews Jason
- Appleby Robert
- Archilli Flavio
- Arnau Romeu Joan
- Artamonov Alexander
- Artuso Marina
- Arzymatov Kenenbek
- Aslanides Elie
- Atzeni Michele
- Bachmann Sebastian
- Back John
- Baker Sophie
- Balagura Vladislav
- Baldini Wander
- Baranov Alexander
- Barlow Roger
- Barsuk Sergey
- Barter William
- Baryshnikov Fedor
- Batozskaya Varvara
- Batsukh Baasansuren
- Battista Vincenzo
- Bay Aurelio
- Beddow John
- Bedeschi Franco
- Bediaga Ignacio
- Beiter Andrew
- Bel Lennaert
- Beliy Nikita
- Bellee Violaine
- Belloli Nicoletta
- Belous Konstantin
- Belyaev Ivan
- Ben-Haim Eli
- Bencivenni Giovanni
- Benson Sean
- Beranek Sarah
- Berezhnoy Alexander
- Bernet Roland
- Berninghoff Daniel
- Bertholet Emilie
- Bertolin Alessandro
- Betancourt Christopher
- Betti Federico
- Bettler Marc-Olivier
- Bezshyiko Iaroslava
- Bhasin Srishti
- Bhom Jihyun
- Bifani Simone
- Billoir Pierre
- Birnkraut Alex
- Bizzeti Andrea
- Bjørn Mikkel
- Blago Michele Piero
- Blake Thomas
- Blanc Frederic
- Blusk Steven
- Bobulska Dana
- Bocci Valerio
- Boente Garcia Oscar
- Boettcher Thomas
- Bondar Alexander
- Bondar Nikolay
- Borghi Silvia
- Borisyak Maxim
- Borsato Martino
- Bossu Francesco
- Boubdir Meriem
- Bowcock Themistocles
- Bozzi Concezio
- Braun Svende
- Brodski Michael
- Brodzicka Jolanta
- Brossa Gonzalo Arnau
- Brundu Davide
- Buchanan Emma
- Buonaura Annarita
- Burr Christopher
- Bursche Albert
- Buytaert Jan
- Byczynski Wiktor
- Cadeddu Sandro
- Cai Hao
- Calabrese Roberto
- Calladine Ryan
- Calvi Marta
- Calvo Gomez Miriam
- Camboni Alessandro
- Campana Pierluigi
- Campora Perez Daniel Hugo
- Capriotti Lorenzo
- Carbone Angelo
- Carboni Giovanni
- Cardinale Roberta
- Cardini Alessandro
- Carniti Paolo
- Carson Laurence
- Carvalho Akiba Kazuyoshi
- Casse Gianluigi
- Cassina Lorenzo
- Cattaneo Marco
- Cavallero Giovanni
- Cenci Riccardo
- Chamont David
- Chapman Matthew George
- Charles Matthew
- Charpentier Philippe
- Chatzikonstantinidis Georgios
- Chefdeville Maximilien
- Chekalina Viktoriia
- Chen Chen
- Chen Shanzhen
- Chitic Stefan-Gabriel
- Chobanova Veronika
- Chrzaszcz Marcin
- Chubykin Alexsei
- Ciambrone Paolo
- Cid Vidal Xabier
- Ciezarek Gregory
- Clarke Peter
- Clemencic Marco
- Cliff Harry
- Closier Joel
- Coco Victor
- Coelho Joao A B
- Cogan Julien
- Cogneras Eric
- Cojocariu Lucian
- Collins Paula
- Colombo Tommaso
- Comerma-Montells Albert
- Contu Andrea
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- Vollhardt Achim
- Voneki Balazs
- Vorobyev Alexey
- Vorobyev Vitaly
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- Walsh John
- Wang Jianchun
- Wang Mengzhen
- Wang Yilong
- Wang Zhenzi
- Ward David
- Wark Heather Mckenzie
- Watson Nigel
- Websdale David
- Weiden Andreas
- Weisser Constantin
- Whitehead Mark
- Wicht Jean
- Wilkinson Guy
- Wilkinson Michael
- Williams Ifan
- Williams Mark Richard James
- Williams Mike
- Williams Timothy
- Wilson Fergus
- Wimberley Jack
- Winn Michael Andreas
- Wishahi Julian
- Wislicki Wojciech
- Witek Mariusz
- Wormser Guy
- Wotton Stephen
- Wyllie Kenneth
- Xiao Dong
- Xie Yuehong
- Xu Ao
- Xu Menglin
- Xu Qingnian
- Xu Zehua
- Xu Zhirui
- Yang Zhenwei
- Yang Zishuo
- Yao Yuezhe
- Yeomans Lauren Emma
- Yin Hang
- Yu Jiesheng
- Yuan Xuhao
- Yushchenko Oleg
- Zarebski Kristian Alexander
- Zavertyaev Mikhail
- Zhang Dongliang
- Zhang Liming
- Zhang Wen Chao
- Zhang Yanxi
- Zhelezov Alexey
- Zheng Yangheng
- Zhu Xianglei
- Zhukov Valery
- Zonneveld Jennifer Brigitta
- Zucchelli Stefano
- Publication venue
- Publication date
- 01/01/2018
- Field of study
The LHCb Upgrade II will fully exploit the flavour-physics opportunities of the HL-LHC, and study additional physics topics that take advantage of the forward acceptance of the LHCb spectrometer. The LHCb Upgrade I will begin operation in 2020. Consolidation will occur, and modest enhancements of the Upgrade I detector will be installed, in Long Shutdown 3 of the LHC (2025) and these are discussed here. The main Upgrade II detector will be installed in long shutdown 4 of the LHC (2030) and will build on the strengths of the current LHCb experiment and the Upgrade I. It will operate at a luminosity up to 2×1034
cm−2s−1, ten times that of the Upgrade I detector. New detector components will improve the intrinsic performance of the experiment in certain key areas. An Expression Of Interest proposing Upgrade II was submitted in February 2017. The physics case for the Upgrade II is presented here in more depth. CP-violating phases will be measured with precisions unattainable at any other envisaged facility. The experiment will probe b → sl+l−and b → dl+l− transitions in both muon and electron decays in modes not accessible at Upgrade I. Minimal flavour violation will be tested with a precision measurement of the ratio of B(B0 → μ+μ−)/B(Bs → μ+μ−). Probing charm CP violation at the 10−5 level may result in its long sought discovery. Major advances in hadron spectroscopy will be possible, which will be powerful probes of low energy QCD. Upgrade II potentially will have the highest sensitivity of all the LHC experiments on the Higgs to charm-quark couplings. Generically, the new physics mass scale probed, for fixed couplings, will almost double compared with the pre-HL-LHC era; this extended reach for flavour physics is similar to that which would be achieved by the HE-LHC proposal for the energy frontier
LHCb upgrade software and computing : technical design report
- Author
- Aaij Roel
- Adeva Bernardo
- Adinolfi Marco
- Aidala Christine Angela
- Ajaltouni Ziad
- Akar Simon
- Albicocco Pietro
- Albrecht Johannes
- Alessio Federico
- Alexander Michael
- Alfonso Albero Alejandro
- Ali Suvayu
- Alkhazov Georgy
- Alvarez Cartelle Paula
- Alves Jr Antonio Augusto
- Amato Sandra
- Amerio Silvia
- Amhis Yasmine
- An Liupan
- Anderlini Lucio
- Andreassi Guido
- Andreotti Mirco
- Andrews Jason
- Appleby Robert
- Archilli Flavio
- Arnau Romeu Joan
- Artamonov Alexander
- Artuso Marina
- Arzymatov Kenenbek
- Aslanides Elie
- Atzeni Michele
- Bachmann Sebastian
- Back John
- Baker Sophie
- Balagura Vladislav
- Baldini Wander
- Baranov Alexander
- Barlow Roger
- Barsuk Sergey
- Barter William
- Baryshnikov Fedor
- Batozskaya Varvara
- Batsukh Baasansuren
- Battista Vincenzo
- Bay Aurelio
- Beddow John
- Bedeschi Franco
- Bediaga Ignacio
- Beiter Andrew
- Bel Lennaert
- Beliy Nikita
- Bellee Violaine
- Belloli Nicoletta
- Belous Konstantin
- Belyaev Ivan
- Ben-Haim Eli
- Bencivenni Giovanni
- Benson Sean
- Beranek Sarah
- Berezhnoy Alexander
- Bernet Roland
- Berninghoff Daniel
- Bertholet Emilie
- Bertolin Alessandro
- Betancourt Christopher
- Betti Federico
- Bettler Marc-Olivier
- Bezshyiko Iaroslava
- Bhasin Srishti
- Bhom Jihyun
- Bifani Simone
- Billoir Pierre
- Birnkraut Alex
- Bizzeti Andrea
- Bjørn Mikkel
- Blago Michele Piero
- Blake Thomas
- Blanc Frederic
- Blusk Steven
- Bobulska Dana
- Bocci Valerio
- Boente Garcia Oscar
- Boettcher Thomas
- Bondar Alexander
- Bondar Nikolay
- Borghi Silvia
- Borisyak Maxim
- Borsato Martino
- Bossu Francesco
- Boubdir Meriem
- Bowcock Themistocles
- Bozzi Concezio
- Braun Svende
- Brodski Michael
- Brodzicka Jolanta
- Brossa Gonzalo Arnau
- Brundu Davide
- Buchanan Emma
- Buonaura Annarita
- Burr Christopher
- Bursche Albert
- Buytaert Jan
- Byczynski Wiktor
- Cadeddu Sandro
- Cai Hao
- Calabrese Roberto
- Calladine Ryan
- Calvi Marta
- Calvo Gomez Miriam
- Camboni Alessandro
- Campana Pierluigi
- Campora Perez Daniel Hugo
- Capriotti Lorenzo
- Carbone Angelo
- Carboni Giovanni
- Cardinale Roberta
- Cardini Alessandro
- Carniti Paolo
- Carson Laurence
- Carvalho Akiba Kazuyoshi
- Casse Gianluigi
- Cassina Lorenzo
- Cattaneo Marco
- Cavallero Giovanni
- Cenci Riccardo
- Chamont David
- Chapman Matthew George
- Charles Matthew
- Charpentier Philippe
- Chatzikonstantinidis Georgios
- Chefdeville Maximilien
- Chekalina Viktoriia
- Chen Chen
- Chen Shanzhen
- Chitic Stefan-Gabriel
- Chobanova Veronika
- Chrzaszcz Marcin
- Chubykin Alexsei
- Ciambrone Paolo
- Cid Vidal Xabier
- Ciezarek Gregory
- Clarke Peter
- Clemencic Marco
- Cliff Harry
- Closier Joel
- Coco Victor
- Coelho Joao A B
- Cogan Julien
- Cogneras Eric
- Cojocariu Lucian
- Collins Paula
- Colombo Tommaso
- Comerma-Montells Albert
- Contu Andrea
- Coombs George
- Coquereau Samuel
- Corti Gloria
- Corvo Marco
- Costa Sobral Cayo Mar
- Couturier Benjamin
- Cowan Greig
- Craik Daniel Charles
- Crocombe Andrew
- Cruz Torres Melissa Maria
- Currie Robert
- D'Ambrosio Carmelo
- d'Argent Philippe
- Da Cunha Marinho Franciole
- Da Silva Cesar Luiz
- Dall'Occo Elena
- Dalseno Jeremy
- Danilina Anna
- Davis Adam
- De Aguiar Francisco Oscar
- De Bruyn Kristof
- De Capua Stefano
- De Cian Michel
- De Miranda Jussara
- De Paula Leandro
- De Serio Marilisa
- De Simone Patrizia
- de Vries Jacco
- Dean Cameron Thomas
- Decamp Daniel
- Del Buono Luigi
- Delaney Blaise
- Dembinski Hans Peter
- Demmer Moritz
- Dendek Adam
- Derkach Denis
- Deschamps Olivier
- Desse Fabrice
- Dettori Francesco
- Dey Biplab
- Di Canto Angelo
- Di Nezza Pasquale
- Didenko Sergey
- Dijkstra Hans
- Dordei Francesca
- Dorigo Mirco
- dos Reis Alberto
- Dosil Suárez Alvaro
- Douglas Lauren
- Dovbnya Anatoliy
- Dreimanis Karlis
- Dufour Laurent
- Dujany Giulio
- Durante Paolo
- Durham John Matthew
- Dutta Deepanwita
- Dzhelyadin Rustem
- Dziewiecki Michal
- Dziurda Agnieszka
- Dzyuba Alexey
- Easo Sajan
- Egede Ulrik
- Egorychev Victor
- Eidelman Semen
- Eisenhardt Stephan
- Eitschberger Ulrich
- Ekelhof Robert
- Eklund Lars
- Ely Scott
- Ene Alexandru
- Escher Stephan
- Esen Sevda
- Evans Timothy
- Falabella Antonio
- Farley Nathanael
- Farry Stephen
- Fazzini Davide
- Färber Christian
- Federici Luca
- Fernandez Declara Placido
- Fernandez Gerard
- Fernandez Prieto Antonio
- Ferrari Fabio
- Ferreira Lopes Lino
- Ferreira Rodrigues Fernando
- Ferro-Luzzi Massimiliano
- Féo Mauricio
- Filippov Sergey
- Fini Rosa Anna
- Fiorini Massimiliano
- Firlej Miroslaw
- Fitzpatrick Conor
- Fiutowski Tomasz
- Fleuret Frederic
- Fontana Marianna
- Fontanelli Flavio
- Forty Roger
- Franco Lima Vinicius
- Frank Markus
- Frei Christoph
- Fu Jinlin
- Funk Wolfgang
- Gabriel Emmy
- Gallas Torreira Abraham
- Galli Domenico
- Gallorini Stefano
- Gambetta Silvia
- Gan Yuyue
- Gandelman Miriam
- Gandini Paolo
- Gao Yuanning
- Garcia Martin Luis Miguel
- Garcia Plana Beatriz
- García Pardiñas Julián
- Garra Tico Jordi
- Garrido Lluis
- Gascon David
- Gaspar Clara
- Gavardi Laura
- Gazzoni Giulio
- Gerick David
- Gersabeck Evelina
- Gersabeck Marco
- Gershon Timothy
- Gerstel Dawid
- Ghez Philippe
- Gianì Sebastiana
- Gibson Valerie
- Girard Olivier Göran
- Giubega Lavinia-Helena
- Gizdov Konstantin
- Gligorov Vladimir
- Golubkov Dmitry
- Golutvin Andrey
- Gomes Alvaro
- Gorelov Igor Vladimirovich
- Gotti Claudio
- Govorkova Ekaterina
- Göbel Carla
- Grabowski Jascha Peter
- Graciani Diaz Ricardo
- Granado Cardoso Luis Alberto
- Graugés Eugeni
- Graverini E
- Graziani Giacomo
- Grecu Alexandru
- Greim Roman
- Griffith Peter
- Grillo Lucia
- Gruber Lukas
- Gruberg Cazon Barak Raimond
- Grünberg Oliver
- Gu Chenxi
- Gushchin Evgeny
- Guz Yury
- Gys Thierry
- Hadavizadeh Thomas
- Hadjivasiliou Christos
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- Vollhardt Achim
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- Vorobyev Alexey
- Vorobyev Vitaly
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- Wilkinson Michael
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- Wimberley Jack
- Winn Michael Andreas
- Wishahi Julian
- Wislicki Wojciech
- Witek Mariusz
- Wormser Guy
- Wotton Stephen
- Wyllie Kenneth
- Xiao Dong
- Xie Yuehong
- Xu Ao
- Xu Menglin
- Xu Qingnian
- Xu Zehua
- Xu Zhirui
- Yang Zhenwei
- Yang Zishuo
- Yao Yuezhe
- Yeomans Lauren Emma
- Yin Hang
- Yu Jiesheng
- Yuan Xuhao
- Yushchenko Oleg
- Zarebski Kristian Alexander
- Zavertyaev Mikhail
- Zhang Dongliang
- Zhang Liming
- Zhang Wen Chao
- Zhang Yanxi
- Zhelezov Alexey
- Zheng Yangheng
- Zhu Xianglei
- Zhukov Valery
- Zonneveld Jennifer Brigitta
- Zucchelli Stefano
- Publication venue
- Publication date
- 01/01/2018
- Field of study
This document reports the Research and Development activities that are carried out in the software and computing domains in view of the upgrade of the LHCb experiment. The implementation of a full software trigger implies major changes in the core software framework, in the event data model, and in the reconstruction algorithms. The increase of the data volumes for both real and simulated datasets requires a corresponding scaling of the distributed computing infrastructure. An implementation plan in both domains is presented, together with a risk assessment analysis
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