59 research outputs found

    Towards Perceived Playfulness and Adoption of Hearables in Smart Cities of China

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    'Hearables' have become important in the aging population. This study investigates whether smart technologies help middle-aged and elderly people accept hearing aid devices in smart cities of China. The authors adopt the PLS-SEM framework to analyze the factors that affect behavioral intention towards adopting hearing aids in smart cities. In order to avoid common method bias, Harman's single factor method is also carried out to make sure the instrument does not introduce a bias. The findings suggest that perceived playfulness and perceived usefulness are principal determinants of hearing aids adoption. In contrast, perceived ease of use, a factor always stressed in literature, does not matter significantly. The results reveal that smart technologies enable patients to access professional services and instructions playfully, which reduces obstacles to adopt hearing aids. This study provides novel insights for policymakers and manufacturers to expand hearing aid adoption by facilitating smart infrastructure and technologies

    Geo-Information Harvesting from Social Media Data

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    As unconventional sources of geo-information, massive imagery and text messages from open platforms and social media form a temporally quasi-seamless, spatially multi-perspective stream, but with unknown and diverse quality. Due to its complementarity to remote sensing data, geo-information from these sources offers promising perspectives, but harvesting is not trivial due to its data characteristics. In this article, we address key aspects in the field, including data availability, analysis-ready data preparation and data management, geo-information extraction from social media text messages and images, and the fusion of social media and remote sensing data. We then showcase some exemplary geographic applications. In addition, we present the first extensive discussion of ethical considerations of social media data in the context of geo-information harvesting and geographic applications. With this effort, we wish to stimulate curiosity and lay the groundwork for researchers who intend to explore social media data for geo-applications. We encourage the community to join forces by sharing their code and data.Comment: Accepted for publication IEEE Geoscience and Remote Sensing Magazin

    Digitalization in omnichannel healthcare supply chain businesses: The role of smart wearable devices

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    The advancement in technology has fostered the prevalence of the Internet of Things (IoT), which enhances healthcare business quality, offers a seamless customer experience, and maximizes turnovers and profits. Consequently, omnichannel services have emerged by integrating online and offline channels and providing customers with more real-time information and services to increase their engagement. Healthcare wearable devices appear as a salient tool to connect healthcare providers and patients and thus become an essential part of the omnichannel environment. Along with this trend, the ethical concerns while using these devices have increasingly intensified and are significant barriers to market expansion. Nevertheless, there is a lack of studies discussing the role of wearables in omnichannel hospital supply chain management and examining the influence of those above concerns on healthcare wearables adoption. Therefore, this study explores these gaps through an integrated approach. Furthermore, we proposed a framework integrating the traditional statistical and machine learning-based approach to analyze a large amount of data; and thereby facilitate a data-driven analytic model to manage omnichannel healthcare supply chain businesses

    Geo-Information Harvesting from Social Media Data

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    As unconventional sources of geo-information, massive imagery and text messages from open platforms and social media form a temporally quasi-seamless, spatially multiperspective stream, but with unknown and diverse quality. Due to its complementarity to remote sensing data, geo-information from these sources offers promising perspectives, but harvesting is not trivial due to its data characteristics. In this article, we address key aspects in the field, including data availability, analysisready data preparation and data management, geo-information extraction from social media text messages and images, and the fusion of social media and remote sensing data. We then showcase some exemplary geographic applications. In addition, we present the first extensive discussion of ethical considerations of social media data in the context of geo-information harvesting and geographic applications. With this effort, we wish to stimulate curiosity and lay the groundwork for researchers who intend to explore social media data for geo-applications. We encourage the community to join forces by sharing their code and data

    Severe low back or lower limb pain is associated with recurrent falls among older Australians

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    Background: Few studies have explored the impact of low back or lower limb pain severity on recurrent (≥2) falls in older adults. Objectives: Investigate the association between the severity of low back or lower limb pain, and ≥2 falls or falls-related injuries. Methods: Community-dwelling Australian males and females in the ASPREE Longitudinal Study of Older Persons (ALSOP), aged ≥70 years. Self-reported, cross-sectional questionnaire data regarding number of falls and falls-related injuries in the last 12 months; and sites and severity of pain experienced on most days. Adjusted relative risks (RR) were estimated from multivariable Poisson regression models, for males and females separately. Results: Of 14,892 ALSOP participants, 13% (n = 1983) reported ≥2 falls (‘recurrent fallers’) in the last 12 months. Males and females who reported severe low back, or severe lower limb pain on most days were more likely to report ≥2 falls in the last 12 months compared to those with mild pain (lower back: males RR = 1.70 and females RR = 1.5, p = 0.001; lower limb: males RR = 2.0, p < 0.001 and females RR = 1.4, p = 0.003). Female recurrent fallers who reported severe low back (RR = 1.3, p = 0.029) or lower limb (RR = 1.2, p = 0.024) pain on most days were more likely to report a falls-related injury in the last 12 months compared to females with mild pain. Conclusion: Severe low back or lower limb pain was associated with an increased likelihood of recurrent falls (males/females) or falls-related injuries (females only). Assessment of severe low back and lower limb pain should be considered as a priority when undertaking falls-risk evaluation. Significance: Severe low back pain, or severe lower limb pain is associated with an increased likelihood of recurrent falls in older males and females, and an increased likelihood of falls-related injuries in older female recurrent fallers. Assessment and management of severe low back and lower limb pain should be prioritized when undertaking falls-risk assessment. Future longitudinal research is required to further interrogate this relationship and its underlying mechanisms

    De Novo Transcriptome of Safflower and the Identification of Putative Genes for Oleosin and the Biosynthesis of Flavonoids

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    Safflower (Carthamus tinctorius L.) is one of the most extensively used oil crops in the world. However, little is known about how its compounds are synthesized at the genetic level. In this study, Solexa-based deep sequencing on seed, leaf and petal of safflower produced a de novo transcriptome consisting of 153,769 unigenes. We annotated 82,916 of the unigenes with gene annotation and assigned functional terms and specific pathways to a subset of them. Metabolic pathway analysis revealed that 23 unigenes were predicted to be responsible for the biosynthesis of flavonoids and 8 were characterized as seed-specific oleosins. In addition, a large number of differentially expressed unigenes, for example, those annotated as participating in anthocyanin and chalcone synthesis, were predicted to be involved in flavonoid biosynthesis pathways. In conclusion, the de novo transcriptome investigation of the unique transcripts provided candidate gene resources for studying oleosin-coding genes and for investigating genes related to flavonoid biosynthesis and metabolism in safflower

    Metabolically Healthy Obesity and High Carotid Intima-Media Thickness in Children and Adolescents: International Childhood Vascular Structure Evaluation Consortium

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    OBJECTIVE It has been argued that metabolically healthy obesity (MHO) does not increase cardiovascular disease (CVD) risk. This study examines the association of MHO with carotid intima-media thickness (cIMT), a proxy of CVD risk, in children and adolescents. RESEARCH DESIGN AND METHODS Data were available for 3,497 children and adolescents aged 6–17 years from five population-based cross-sectional studies in Brazil, China, Greece, Italy, and Spain. Weight status categories (normal, overweight, and obese) were defined using BMI cutoffs from the International Obesity Task Force. Metabolic status (defined as "healthy" [no risk factors] or "unhealthy" [one or more risk factors]) was based on four CVD risk factors: elevated blood pressure, elevated triglyceride levels, reduced HDL cholesterol, and elevated fasting glucose. High cIMT was defined as cIMT ≥90th percentile for sex, age, and study population. Logistic regression model was used to examine the association of weight and metabolic status with high cIMT, with adjustment for sex, age, race/ethnicity, and study center. RESULTS In comparison with metabolically healthy normal weight, odds ratios (ORs) for high cIMT were 2.29 (95% CI 1.58–3.32) for metabolically healthy overweight and 3.91 (2.46–6.21) for MHO. ORs for high cIMT were 1.44 (1.03–2.02) for unhealthy normal weight, 3.49 (2.51–4.85) for unhealthy overweight, and 6.96 (5.05–9.61) for unhealthy obesity. CONCLUSIONS Among children and adolescents, cIMT was higher for both MHO and metabolically healthy overweight compared with metabolically healthy normal weight. Our findings reinforce the need for weight control in children and adolescents irrespective of their metabolic status

    The sustainable materials roadmap

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    Over the past 150 years, our ability to produce and transform engineered materials has been responsible for our current high standards of living, especially in developed economies. However, we must carefully think of the effects our addiction to creating and using materials at this fast rate will have on the future generations. The way we currently make and use materials detrimentally affects the planet Earth, creating many severe environmental problems. It affects the next generations by putting in danger the future of the economy, energy, and climate. We are at the point where something must drastically change, and it must change now. We must create more sustainable materials alternatives using natural raw materials and inspiration from nature while making sure not to deplete important resources, i.e. in competition with the food chain supply. We must use less materials, eliminate the use of toxic materials and create a circular materials economy where reuse and recycle are priorities. We must develop sustainable methods for materials recycling and encourage design for disassembly. We must look across the whole materials life cycle from raw resources till end of life and apply thorough life cycle assessments (LCAs) based on reliable and relevant data to quantify sustainability. We need to seriously start thinking of where our future materials will come from and how could we track them, given that we are confronted with resource scarcity and geographical constrains. This is particularly important for the development of new and sustainable energy technologies, key to our transition to net zero. Currently 'critical materials' are central components of sustainable energy systems because they are the best performing. A few examples include the permanent magnets based on rare earth metals (Dy, Nd, Pr) used in wind turbines, Li and Co in Li-ion batteries, Pt and Ir in fuel cells and electrolysers, Si in solar cells just to mention a few. These materials are classified as 'critical' by the European Union and Department of Energy. Except in sustainable energy, materials are also key components in packaging, construction, and textile industry along with many other industrial sectors. This roadmap authored by prominent researchers working across disciplines in the very important field of sustainable materials is intended to highlight the outstanding issues that must be addressed and provide an insight into the pathways towards solving them adopted by the sustainable materials community. In compiling this roadmap, we hope to aid the development of the wider sustainable materials research community, providing a guide for academia, industry, government, and funding agencies in this critically important and rapidly developing research space which is key to future sustainability.journal articl

    Robust estimation of bacterial cell count from optical density

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    Optical density (OD) is widely used to estimate the density of cells in liquid culture, but cannot be compared between instruments without a standardized calibration protocol and is challenging to relate to actual cell count. We address this with an interlaboratory study comparing three simple, low-cost, and highly accessible OD calibration protocols across 244 laboratories, applied to eight strains of constitutive GFP-expressing E. coli. Based on our results, we recommend calibrating OD to estimated cell count using serial dilution of silica microspheres, which produces highly precise calibration (95.5% of residuals &lt;1.2-fold), is easily assessed for quality control, also assesses instrument effective linear range, and can be combined with fluorescence calibration to obtain units of Molecules of Equivalent Fluorescein (MEFL) per cell, allowing direct comparison and data fusion with flow cytometry measurements: in our study, fluorescence per cell measurements showed only a 1.07-fold mean difference between plate reader and flow cytometry data
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