FBG-Based Creep Analysis of GFRP Materials Embedded in Concrete

This paper presents a typical study regarding the creep interaction behavior between prestressed glass fiber reinforced polymer (GFRP) bar and concrete when this GFRP bar is subjected to a constant external pullout force. A number of optical fiber Bragg grating (FBG) sensors were mounted on GFRP bar surface by using an innovative installation method to measure strain distributions. Test results indicate that the complicated interaction at GFRP bar-concrete interface can be evaluated using a transitional factor. Variation trends of this transitional factor indicate three typical zones characterized by different strain/stress variation trends of the GFRP bar when prestress values are sustained at specific levels. These three typical zones include stress release zone, stress transition zone, and continuous tension zone. Test results also suggest that the instant stress loss at the interaction interface between concrete and GFRP bar was quite limited (less than 5%) in present test. Contributed proportion of each GFRP bar section was obtained to represent the creep behavior of the GFRP bar embedded in concrete. This investigation improved the understanding of the short-term interaction behavior between prestressed GFRP bar and concrete

Ds0(2317)D_{s0}(2317) as a tetraquark state with QCD sum rules in heavy quark limit

In this article, we take the point of view that the charmed scalar meson $D_{s0}(2317)$ be a tetraquark state and devote to calculate its mass within the framework of the QCD sum rules approach in the heavy quark limit. The numerical values for the mass of the $D_{s0}(2317)$ are consistent with the experimental data, there must be some tetraquark component in the scalar meson $D_{s0}(2317)$. Detailed discussions about the threshold parameter and Borel parameter for the multiquark states are also presented.Comment: 9 pages, 1 figure, third versio

Decay constants of the pseudoscalar mesons in the framework of the coupled Schwinger-Dyson equation and Bethe-Salpeter equation

In this article, we investigate the structures of the pseudoscalar mesons ($\pi$, $K$, $D$, $D_s$, $B$ and $B_s$) in the framework of the coupled rainbow Schwinger-Dyson equation and ladder Bethe-Salpeter equation with the confining effective potential (infrared modified flat bottom potential). The Schwinger-Dyson functions for the $u$, $d$ and $s$ quarks are greatly renormalized at small momentum region and the curves are steep at about $q^2=1GeV^2$ which indicates an explicitly dynamical symmetry breaking. The Euclidean time fourier transformed quark propagators have no mass poles in the time-like region which naturally implements confinement. As for the $c$ and $b$ quarks, the current masses are very large, the renormalization are more tender, however, mass poles in the time-like region are also absent. The Bethe-Salpeter wavefunctions for those mesons have the same type (Gaussian type) momentum dependence and center around small momentum which indicate that the bound states exist in the infrared region. The decay constants for those pseudoscalar mesons are compatible with the values of experimental extractions and theoretical calculations, such as lattice simulations and QCD sum rules.Comment: 10 pages, 4 figures, Revised Versio

Decay constants of the pseudoscalar charmonium and bottomonium

In this article, we investigate the structures of the pseudoscalar charmonium and bottomonium in the framework of the coupled rainbow Schwinger-Dyson equation and ladder Bethe-Salpeter equation with the confining effective potential (infrared modified flat bottom potential). As the current masses are very large, the dressing or renormalization for the $c$ and $b$ quarks are tender, however, mass poles in the timelike region are absent. The Euclidean time fourier transformed quark propagator has no mass poles in the timelike region which naturally implements confinement. The Bethe-Salpeter wavefunctions for those mesons have the same type (Gaussian type) momentum dependence and center around zero momentum with spatial extension to about $q^2=1GeV^2$ which happen to be the energy scale for Chiral symmetry breaking, the strong interactions in the infrared region result in bound states. The decay constants for those pseudoscalar heavy quarkonia are compatible with the values of experimental extractions and theoretical calculations.Comment: 12 pages, 1 figure; Revised versio

Cryptochromes and Hormone Signal Transduction under Near-Zero Magnetic Fields: New Clues to Magnetic Field Effects in a Rice Planthopper

Although there are considerable reports of magnetic field effects (MFE) on organisms, very little is known so far about the MFE-related signal transduction pathways. Here we establish a manipulative near-zero magnetic field (NZMF) to investigate the potential signal transduction pathways involved in MFE. We show that exposure of migratory white-backed planthopper, Sogatella furcifera, to the NZMF results in delayed egg and nymphal development, increased frequency of brachypterous females, and reduced longevity of macropterous female adults. To understand the changes in gene expression underlying these phenotypes, we examined the temporal patterns of gene expression of (i) CRY1 and CRY2 as putative magnetosensors, (ii) JHAMT, FAMeT and JHEH in the juvenile hormone pathway, (iii) CYP307A1 in the ecdysone pathway, and (iv) reproduction-related Vitellogenin (Vg). The significantly altered gene expression of CRY1 and CRY2 under the NZMF suggest their developmental stage-specific patterns and potential upstream location in magnetic response. Gene expression patterns of JHAMT, JHEH and CYP307A1 were consistent with the NZMF-triggered delay in nymphal development, higher proportion of brachypterous female adults, and the shortened longevity of macropterous female adults, which show feasible links between hormone signal transduction and phenotypic MFE. By conducting manipulative NZMF experiments, our study suggests an important role of the geomagnetic field (GMF) in modulating development and physiology of insects, provides new insights into the complexity of MFE-magnetosensitivity interactions, and represents an initial but crucial step forward in understanding the molecular basis of cryptochromes and hormone signal transduction involved in MFE

Sarcocrassocolides M–O, Bioactive Cembranoids from the Dongsha Atoll Soft Coral Sarcophyton crassocaule

Three new cembranoids, sarcocrassocolides M–O (1–3), have been isolated from the soft coral Sarcophyton crassocaule. The structures of the metabolites were determined by extensive spectroscopic analysis. Compounds 1–3 were shown to exhibit moderate cytotoxicity toward a limited panel of cancer cell lines and display significant in vitro anti-inflammatory activity in LPS-stimulated RAW264.7 macrophage cells by inhibiting the expression of the iNOS protein

Two-year outcomes of ab interno trabeculectomy with the Trabectome for Chinese primary open angle glaucoma: a retrospective multicenter study

AIM: To evaluate the 2-year efficacy and safety of ab interno trabeculectomy with the Trabectome in Chinese primary open angle glaucoma (POAG) patients. METHODS: This was a multicenter, retrospective, observational study and included POAG patients with or without visually-significant cataracts. The Chinese patients were enrolled from three glaucoma centers and a group of comparable Japanese POAG patients was analyzed from our international Trabectome database. The patients received Trabectome or a combined surgery with phacoemulsification and intraocular lens implantation. The primary outcome was intraocular pressure (IOP) reduction. Secondary outcomes included reduction of glaucoma medications, surgical complications, and success at 2y. Success was defined as: 1) IOP≤21 mm Hg and at least 20% IOP reduction from baseline after 3mo at any two consecutive visits; 2) no additional glaucoma surgery required. RESULTS: A total of 42 Chinese POAG patients from three glaucoma centers were enrolled. Twelve patients underwent Trabectome surgery combined with phacoemulsification and intraocular lens implantation while the remainder underwent Trabectome surgery alone. Thirteen patients had a history of failed glaucoma surgery and were considered as complicated cases. In China data, the mean preoperative IOP was 21.4±1.23 mm Hg. The Trabectome lowered IOP to 17.9±1.8 mm Hg at 2y (P=0.05). The number of glaucoma medications also decreased significantly from a baseline of 2.0±0.9 to 1.1±0.8 at 2y post-surgery (P=0.04). The overall 2-year success rate was 78%, with patients undergoing combined surgery having a higher success rate compared with those undergoing Trabectome surgery alone (100% vs 76%). In Japan data, the mean preoperative IOP was 20.8±7.7 mm Hg. The Trabectome lowered IOP to 12.20±2.0 mm Hg at 2y. The number of glaucoma medications also decreased significantly from a baseline of 2.1±0.9 to 3.4±0.6 at 2y post-surgery. In all patients, no major complications were seen. CONCLUSION: Surgery with the Trabectome appears to be an efficient and safe procedure in Chinese POAG patients in the long-term

Functional building blocks for scalable multipartite entanglement in optical lattices

Featuring excellent coherence and operated parallelly, ultracold atoms in optical lattices form a competitive candidate for quantum computation. For this, a massive number of parallel entangled atom pairs have been realized in superlattices. However, the more formidable challenge is to scale-up and detect multipartite entanglement due to the lack of manipulations over local atomic spins in retro-reflected bichromatic superlattices. Here we developed a new architecture based on a cross-angle spin-dependent superlattice for implementing layers of quantum gates over moderately-separated atoms incorporated with a quantum gas microscope for single-atom manipulation. We created and verified functional building blocks for scalable multipartite entanglement by connecting Bell pairs to one-dimensional 10-atom chains and two-dimensional plaquettes of $2\times4$ atoms. This offers a new platform towards scalable quantum computation and simulation

Overexpression of Secreted Frizzled-Related Protein 1 Inhibits Bone Formation and Attenuates Parathyroid Hormone Bone Anabolic Effects

Secreted frizzled-related protein 1 (sFRP1) is an antagonist of Wnt signaling, an important pathway in maintaining bone homeostasis. In this study we evaluated the skeletal phenotype of mice overexpressing sFRP1 (sFRP1 Tg) and the interaction of parathyroid hormone (PTH) treatment and sFRP1 (over)expression. Bone mass and microarchitecture were measured by micro-computed tomography (µCT). Osteoblastic and osteoclastic cell maturation and function were assessed in primary bone marrow cell cultures. Bone turnover was assessed by biochemical markers and dynamic bone histomorphometry. Real-time PCR was used to monitor the expression of several genes that regulate osteoblast maturation and function in whole bone. We found that trabecular bone mass measurements in distal femurs and lumbar vertebral bodies were 22% and 51% lower in female and 9% and 33% lower in male sFRP1 Tg mice, respectively, compared with wild-type (WT) controls at 3 months of age. Genes associated with osteoblast maturation and function, serum bone formation markers, and surface based bone formation were significantly decreased in sFRP1 Tg mice of both sexes. Bone resorption was similar between sFRP1 Tg and WT females and was higher in sFRP1 Tg male mice. Treatment with hPTH(1-34) (40 µg/kg/d) for 2 weeks increased trabecular bone volume in WT mice (females: +30% to 50%; males: +35% to 150%) compared with sFRP1 Tg mice (females: +5%; males: +18% to 54%). Percentage increases in bone formation also were lower in PTH-treated sFRP1 Tg mice compared with PTH-treated WT mice. In conclusion, overexpression of sFRP1 inhibited bone formation as well as attenuated PTH anabolic action on bone. The gender differences in the bone phenotype of the sFRP1 Tg animal warrants further investigation. © 2010 American Society for Bone and Mineral Researc