65,469 research outputs found
Internet Service Provider Liability for Contributory Trademark Infringement After Gucci
[I]f a manufacturer or distributor intentionally induces another to infringe a trademark, or if it continues to supply its product to one whom it knows or has reason to know is engaging in trademark infringement, the manufacturer or distributor is contributorially responsible for any harm done as a result of the deceit
Specific wavelength colorimeter
A self contained, specific wavelength, single beam colorimeter is described for direct spectrophotometric measurement of the concentration of a given solute in a test sample. An electrical circuit employing a photoconductive cell converts the optical output into a linear, directly readable meter output. The colorimeter is simple to operate and is adapted for use in zero gravity conditions. In a specific application, the colorimeter is designed to analyze the concentration of iodine in potable water carried aboard a space vehicle such as the 4B stage of Skylab
A Systems-Based Approach to the Identification of User/Infrastructure Interdependencies as a Precursor to Identifying Opportunities to Improve Infrastructure Project Value/Cost Ratios
The bulk of the investment needed for infrastructure renewal in the United Kingdom will have to come from private
sector investors, who will require attractive value/cost ratios. Government recognises infrastructure interdependencies
can help deliver these, but returns remain uncertain. New business models are required to overcome this problem,
which take account of enterprise-centred infrastructure interdependencies (interdependencies between social and
economic enterprises and the infrastructures they use). The complex and closely coupled nature of enterprise and
infrastructure systems can stand in the way of identifying these interdependencies; however, model-based systems
engineering techniques offer a framework for dealing with this complexity. This paper describes research that the
iBUILD project is doing to develop a methodology for modelling the interdependencies between infrastructure and
the enterprises that use it, as a precursor to identifying opportunities to improve infrastructure project value/cost
ratios. The methodology involves: identifying the suite of policy, strategy and operational documents relating to the
enterprise-of-interest; eliciting system data from the documents and integrating it to create an enterprise system
model; and, generating N2 diagrams from the model to identify the interdependencies
The “Irish Born” One American Citizenship Amendment
Our Constitution has a deferred maintenance problem because we have fallen out of the habit of tending to its upkeep ourselves. The silver lining is a double benefit from any constitutional maintenance projects that we undertake now. These projects are good not only for what they do to our Constitution, but also for making us exercise self-government muscles that have atrophied from civic sloth.
Fortunately, the time has never been better to repeal one of our Constitution’s most pointlessly exclusionary provisions. The President of the United States is married to a naturalized citizen. And nobody can legitimately question the patriotism of the First Lady of the United States, Melania Trump. She flies on Air Force One with the President and represents our country both at home and abroad. As an American citizen, she is as much an American as the President himself. This fortuitous circumstance is just one reason it might be possible to eliminate what the Supreme Court has identified as the only legal difference between naturalized and natural born citizens— eligibility for the presidency
Odyssey: a semi-automated pipeline for phasing, imputation, and analysis of genome-wide genetic data
BACKGROUND:
Genome imputation, admixture resolution and genome-wide association analyses are timely and computationally intensive processes with many composite and requisite steps. Analysis time increases further when building and installing the run programs required for these analyses. For scientists that may not be as versed in programing language, but want to perform these operations hands on, there is a lengthy learning curve to utilize the vast number of programs available for these analyses.
RESULTS:
In an effort to streamline the entire process with easy-to-use steps for scientists working with big data, the Odyssey pipeline was developed. Odyssey is a simplified, efficient, semi-automated genome-wide imputation and analysis pipeline, which prepares raw genetic data, performs pre-imputation quality control, phasing, imputation, post-imputation quality control, population stratification analysis, and genome-wide association with statistical data analysis, including result visualization. Odyssey is a pipeline that integrates programs such as PLINK, SHAPEIT, Eagle, IMPUTE, Minimac, and several R packages, to create a seamless, easy-to-use, and modular workflow controlled via a single user-friendly configuration file. Odyssey was built with compatibility in mind, and thus utilizes the Singularity container solution, which can be run on Linux, MacOS, and Windows platforms. It is also easily scalable from a simple desktop to a High-Performance System (HPS).
CONCLUSION:
Odyssey facilitates efficient and fast genome-wide association analysis automation and can go from raw genetic data to genome: phenome association visualization and analyses results in 3-8 h on average, depending on the input data, choice of programs within the pipeline and available computer resources. Odyssey was built to be flexible, portable, compatible, scalable, and easy to setup. Biologists less familiar with programing can now work hands on with their own big data using this easy-to-use pipeline
Maser Source Finding Methods in HOPS
The {\bf H}{\bf O} Southern Galactic {\bf P}lane {\bf S}urvey (HOPS) has
observed 100 square degrees of the Galactic plane, using the Mopra radio
telescope to search for emission from multiple spectral lines in the 12\,mm
band (19.5\,--\,27.5\,GHz). Perhaps the most important of these spectral lines
is the 22.2\,GHz water maser transition. We describe the methods used to
identify water maser candidates and subsequent confirmation of the sources. Our
methods involve a simple determination of likely candidates by searching peak
emission maps, utilising the intrinsic nature of water maser emission -
spatially unresolved and spectrally narrow-lined. We estimate completeness
limits and compare our method with results from the {\sc Duchamp} source
finder. We find that the two methods perform similarly. We conclude that the
similarity in performance is due to the intrinsic limitation of the noise
characteristics of the data. The advantages of our method are that it is
slightly more efficient in eliminating spurious detections and is simple to
implement. The disadvantage is that it is a manual method of finding sources
and so is not practical on datasets much larger than HOPS, or for datasets with
extended emission that needs to be characterised. We outline a two-stage method
for the most efficient means of finding masers, using {\sc Duchamp}.Comment: 8 pages, 1 table, 4 figures. Accepted for publication in PASA special
issue on Source Finding & Visualisatio
Policy coordination and financial intermediaries
Summary of proceedings from the 1986 Fall Academic Conference sponsored by the Federal Reserve Bank of San FranciscoMonetary policy ; Monetary policy - United States ; International economic relations ; Bank supervision ; Financial institutions
Kinematics of a hot massive accretion disk candidate
Characterizing rotation, infall and accretion disks around high-mass
protostars is an important topic in massive star formation research. With the
Australia Telescope Compact Array and the Very Large Array we studied a massive
disk candidate at high angular resolution in ammonia (NH3(4,4) & (5,5)) tracing
the warm disk but not the envelope. The observations resolved at ~0.4''
resolution (corresponding to ~1400AU) a velocity gradient indicative of
rotation perpendicular to the molecular outflow. Assuming a Keplerian accretion
disk, the estimated protostar-disk mass would be high, similar to the
protostellar mass. Furthermore, the position-velocity diagram exhibits
additional deviation from a Keplerian rotation profile which may be caused by
infalling gas and/or a self-gravitating disk. Moreover, a large fraction of the
rotating gas is at temperatures >100K, markedly different to typical low-mass
accretion disks. In addition, we resolve a central double-lobe cm continuum
structure perpendicular to the rotation. We identify this with an ionized,
optically thick jet.Comment: 5 pages, 3 figures, accepted for Astrophysical Journal Letters, a
high-resolution version of the draft can be found at
http://www.mpia.de/homes/beuther/papers.htm
Exercise rehabilitation for recovery from critical illness (Protocol)
Queen Margaret University, Edinburgh, UK.
As part of an ongoing research education programme.This is the protocol for a review and there is no abstract. The objectives are as follows:
The objective of this systematic review is to assess the effectiveness of exercise rehabilitation programmes, initiated after ICU discharge, on improving functional exercise capacity and quality of life in adult ICU survivors who have been mechanically ventilated for more than 24 hours.
We will compare an exercise intervention to any other intervention or a control or 'usual care' programme. Exercise includes any structured or taught programmes. Respiratory or inspiratory muscle training is excluded due to it being initiated within the ICU environment, for example with weaning from a ventilator, and not as post-discharge rehabilitation as required for this review.sch_phyAngus 1997
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Angus 2003
Angus DC, Carlet J, Brussels Roundtable 2002 Participants.
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[PUBMED: 12536269 ]
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Elliott D, McKinley S, Alison J, Aitken L, King M. Study protocol:
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Gill TM, Baker DI, Gottschalk M, Peduzzi PN, Allore H, Byers A.
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Higgins 2008
Higgins JPT, Green S, editors. Cochrane Handbook for Systematic
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Available from www.cochrane-handbook.org: The Cochrane
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Iversen 2003
Iversen MD, Fossel AH, Katz JN. Enhancing function in older
adults with chronic low back pain: a pilot study of endurance
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Jolliffe J, Rees K, Taylor RRS, Thompson DR, Oldridge N,
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Kouidi E. Exercise training in dialysis patients: why, when, and
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Krishnan 2002
Krishnan KR, Delong M, Kraemer H, Carney R, Spiegel D,
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Lavie 2009
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Martin M, Salim A, Murray J, Demetriades D, Belzberg H, Rhee P.
The decreasing incidence and mortality of acute respiratory distress
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Mazzeo RS, Tanaka H. Exercise prescription for the elderly: current
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RevMan 5.0
The Nordic Cochrane Centre, The Cochrane Collaboration.
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Cochrane Centre, The Cochrane Collaboration, 2008.
Schweickert 2009
Schweickert WD, Pohlman MC, Pohlman AS, Nigos C, Pawlik AJ,
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Smith TP, Kennedy SL, Smith M, Orent S, Fleshner M.
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Wiles L, Stiller K. Passive limb movements for patients in an
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[PUBMED: 10894639]
Indicates the major publication for the study8pub1756pubArt.
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