Does Nursing Bias Affect Patients: A Quality Improvement Project

Nursing bias topics to be touched on will be bias from nurses towards patients with the following: • substance abuse history • mental disorders • different races/ethnicities • sexual orientations It is important to address the problem of nursing bias towards certain people primarily because it is affecting patient care/patient outcomes.https://scholarworks.moreheadstate.edu/celebration_posters_2024/1012/thumbnail.jp

Eating Pattern Response to a Low-Fat Diet Intervention and Cardiovascular Outcomes in Normotensive Women: The Women's Health Initiative.

BackgroundWomen without cardiovascular disease (CVD) or hypertension at baseline assigned to intervention in the Women's Health Initiative Dietary Modification (DM) trial experienced 30% lower risk of coronary heart disease (CHD), whereas results in women with hypertension or prior CVD could have been confounded by postrandomization use of statins.ObjectivesIntervention participants reported various self-selected changes to achieve the 20% total fat goals. Reviewed are intervention compared with comparison group HRs for CHD, stroke, and total CVD in relation to specific dietary changes in normotensive participants.MethodsDietary change was assessed by comparing baseline with year 1 FFQ data in women (n = 10,371) without hypertension or CVD at baseline with intake of total fat above the median to minimize biases due to use of the FFQ in trial eligibility screening.ResultsIntervention participants self-reported compensating reduced energy intake from total fat by increasing carbohydrate and protein. Specifically they increased plant protein, with those in the upper quartile (increased total protein by ≥3.3% of energy) having a CHD HR of 0.39 (95% CI: 0.22, 0.71), compared with 0.92 (95% CI: 0.57, 1.48) for those in the lower quartile of change (decreased total protein ≥0.6% of energy), with P-trend of 0.04. CHD HR did not vary significantly with change in percentage energy from carbohydrate, and stroke HR did not vary significantly with any macronutrient changes. Scores reflecting adherence to recommended dietary patterns including the Dietary Approaches to Stop Hypertension Trial and the Healthy Eating Index showed favorable changes in the intervention group.ConclusionsIntervention group total fat reduction replaced with increased carbohydrate and some protein, especially plant-based protein, was related to lower CHD risk in normotensive women without CVD who reported high baseline total fat intake. This trial was registered at clinicaltrials.gov as NCT00000611. Link to the WHI trial protocol: https://www.whi.org/about/SitePages/Dietary%20Trial.aspx

Fatores associados ao Aleitamento Materno Exclusivo na Amazônia Legal e no Nordeste, Brasil, 2010

OBJETIVO: O objetivo foi identificar fatores associados ao aleitamento materno exclusivo em crianças menores de seis meses de idade, residentes na Amazônia Legal e no Nordeste do Brasil, com base nos dados da pesquisa de avaliação da atenção ao pré-natal e aos menores de um ano de idade em 2010. MÉTODOS: Consideraram-se fatores associadas ao aleitamento exclusivo as variáveis sociodemográficos e de assistência ao pré-natal, parto e puerpério que mantiveram p<0,05 em análise multivariada. RESULTADOS: Em ambas as regiões, a prevalência de aleitamento materno exclusivo apresentou declínio com aumento da idade da criança, que se configurou na principal variável associada ao desmame precoce. Na Amazônia Legal, a probabilidade de aleitamento materno exclusivo foi maior para: mães com 35 ou mais anos de idade, mães que residiam nas capitais dos estados e mães que amamentaram na primeira hora de vida da criança. No Nordeste, a probabilidade de aleitamento materno exclusivo também foi maior para mães com 35 ou mais anos de idade. CONCLUSÃO: Os fatores associados ao aleitamento materno exclusivo foram idade da criança e idade da mãe nas duas regiões, localização de moradia e mamada na primeira hora na Amazônia Legal, o que sugere a necessidade de estratégias diferenciadas para a promoção do aleitamento materno.OBJECTIVE: The objective of this study was to identify the factors associated with exclusive breastfeeding in children aged less than six months from the Brazilian Legal Amazon and Northeast regions. METHODS: The study used data from a survey that assessed prenatal and infant (<1 year) care in 2010. Sociodemographic, prenatal, delivery, and puerperium care factors with p<0.05 in multivariate analysis were associated with exclusive breastfeeding. RESULTS: For both regions, the prevalence of exclusive breastfeeding decreased with age, which was the main variable associated with early weaning. In the Legal Amazon, exclusive breastfeeding prevailed among: mothers aged 35 years or more; mothers living in state capitals; and mothers who breastfed on the first hour of life. In the Northeast, the probability of exclusive breastfeeding was greater for mothers aged 35 years or more. CONCLUSION: The factors associated with exclusive breastfeeding were child's and mother's age in both regions; and residence location and breastfeeding in the first hour of life in the Legal Amazon, suggesting the need of differentiated strategies for the promotion of exclusive breastfeeding

Enteric Neurospheres Are Not Specific to Neural Crest Cultures: Implications for Neural Stem Cell Therapies

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited

Characterizing 51 Eri b from 1-5 μ\mum: a partly-cloudy exoplanet

We present spectro-photometry spanning 1-5 $\mu$m of 51 Eridani b, a 2-10 M$_\text{Jup}$ planet discovered by the Gemini Planet Imager Exoplanet Survey. In this study, we present new $K1$ (1.90-2.19 $\mu$m) and $K2$ (2.10-2.40 $\mu$m) spectra taken with the Gemini Planet Imager as well as an updated $L_P$ (3.76 $\mu$m) and new $M_S$ (4.67 $\mu$m) photometry from the NIRC2 Narrow camera. The new data were combined with $J$ (1.13-1.35 $\mu$m) and $H$ (1.50-1.80 $\mu$m) spectra from the discovery epoch with the goal of better characterizing the planet properties. 51 Eri b photometry is redder than field brown dwarfs as well as known young T-dwarfs with similar spectral type (between T4-T8) and we propose that 51 Eri b might be in the process of undergoing the transition from L-type to T-type. We used two complementary atmosphere model grids including either deep iron/silicate clouds or sulfide/salt clouds in the photosphere, spanning a range of cloud properties, including fully cloudy, cloud free and patchy/intermediate opacity clouds. Model fits suggest that 51 Eri b has an effective temperature ranging between 605-737 K, a solar metallicity, a surface gravity of $\log$(g) = 3.5-4.0 dex, and the atmosphere requires a patchy cloud atmosphere to model the SED. From the model atmospheres, we infer a luminosity for the planet of -5.83 to -5.93 ($\log L/L_{\odot}$), leaving 51 Eri b in the unique position as being one of the only directly imaged planet consistent with having formed via cold-start scenario. Comparisons of the planet SED against warm-start models indicates that the planet luminosity is best reproduced by a planet formed via core accretion with a core mass between 15 and 127 M$_{\oplus}$.Comment: 27 pages, 19 figures, Accepted for publication in The Astronomical Journa

Caveolae-dependent and -independent uptake of albumin in cultured rodent pulmonary endothelial cells

Although a critical role for caveolae-mediated albumin transcytosis in pulmonary endothelium is well established, considerably less is known about caveolae-independent pathways. In this current study, we confirmed that cultured rat pulmonary microvascular (RPMEC) and pulmonary artery (RPAEC) endothelium endocytosed Alexa488-labeled albumin in a saturable, temperature-sensitive mode and internalization resulted in co-localization by fluorescence microscopy with cholera B toxin and caveolin-1. Although siRNA to caveolin-1 (cav-1) in RPAEC significantly inhibited albumin uptake, a remnant portion of albumin uptake was cav-1-independent, suggesting alternative pathways for albumin uptake. Thus, we isolated and cultured mouse lung endothelial cells (MLEC) from wild type and cav-1-/- mice and noted that ∼ 65% of albumin uptake, as determined by confocal imaging or live cell total internal reflectance fluorescence microscopy (TIRF), persisted in total absence of cav-1. Uptake of colloidal gold labeled albumin was evaluated by electron microscopy and demonstrated that albumin uptake in MLEC from cav-1-/- mice was through caveolae-independent pathway(s) including clathrin-coated pits that resulted in endosomal accumulation of albumin. Finally, we noted that albumin uptake in RPMEC was in part sensitive to pharmacological agents (amiloride [sodium transport inhibitor], Gö6976 [protein kinase C inhibitor], and cytochalasin D [inhibitor of actin polymerization]) consistent with a macropinocytosis-like process. The amiloride sensitivity accounting for macropinocytosis also exists in albumin uptake by both wild type and cav-1 -/- MLEC. We conclude from these studies that in addition to the well described caveolar-dependent pulmonary endothelial cell endocytosis of albumin, a portion of overall uptake in pulmonary endothelial cells is cav-1 insensitive and appears to involve clathrin-mediated endocytosis and macropinocytosis-like process. © 2013 Li et al

Characterizing 51 Eri b from 1 to 5 μm : a partly cloudy exoplanet

Funding: This work was supported by NSF grants AST-1411868 (A.R., J.L.P., B.M.), AST-1518332 (R.J.D.R.), and DGE-1311230 (K.W.D.). F.M. and E.N. are supported by NASA Grant NNX14AJ80G. This work was supported by Fonds de Recherche du Québec (J.R., R.D., D.L.). K.M.M. and T.S.B. are supported by the NASA Exoplanets Research Program (XRP) by cooperative agreement NNX16AD44G. G.V. and J.K.W. acknowledge JPL’s ESI program for GPI-related funding.We present spectrophotometry spanning 1–5 μm of 51 Eridani b, a 2–10 MJup planet discovered by the Gemini Planet Imager Exoplanet Survey. In this study, we present new K1 (1.90–2.19 μm) and K2 (2.10–2.40 μm) spectra taken with the Gemini Planet Imager as well as an updated LP (3.76 μm) and new MS (4.67 μm) photometry from the NIRC2 Narrow camera. The new data were combined with J (1.13–1.35 μm) and H (1.50–1.80 μm) spectra from the discovery epoch with the goal of better characterizing the planet properties. The 51 Eri b photometry is redder than field brown dwarfs as well as known young T-dwarfs with similar spectral type (between T4 and T8), and we propose that 51 Eri b might be in the process of undergoing the transition from L-type to T-type. We used two complementary atmosphere model grids including either deep iron/silicate clouds or sulfide/salt clouds in the photosphere, spanning a range of cloud properties, including fully cloudy, cloud-free, and patchy/intermediate-opacity clouds. The model fits suggest that 51 Eri b has an effective temperature ranging between 605 and 737 K, a solar metallicity, and a surface gravity of log(g) = 3.5–4.0 dex, and the atmosphere requires a patchy cloud atmosphere to model the spectral energy distribution (SED). From the model atmospheres, we infer a luminosity for the planet of −5.83 to −5.93 (log L/L⊙), leaving 51 Eri b in the unique position of being one of the only directly imaged planets consistent with having formed via a cold-start scenario. Comparisons of the planet SED against warm-start models indicate that the planet luminosity is best reproduced by a planet formed via core accretion with a core mass between 15 and 127 M⊕.Publisher PDFPeer reviewe